Result of FASTA (omim) for
pF1KSDA0223
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0223, 1136 aa
1>>>pF1KSDA0223 1136 - 1136 aa - 1136 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2359+/-0.000406; mu= 8.9346+/- 0.025
mean_var=191.5881+/-39.290, 0's: 0 Z-trim(118.4): 263 B-trim: 929 in 1/56
Lambda= 0.092660
statistics sampled from 30890 (31223) to 30890 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.366), width: 16
Scan time: 12.740
The best scores are: opt bits E(85289)
NP_036424 (OMIM: 601155) minor histocompatibility (1136) 7490 1014.9 0
NP_001308161 (OMIM: 601155) minor histocompatibili (1140) 7306 990.3 0
NP_001245257 (OMIM: 601155) minor histocompatibili (1152) 7305 990.2 0
NP_001269264 (OMIM: 601155) minor histocompatibili (1019) 6563 890.9 0
XP_011526162 (OMIM: 601155) PREDICTED: minor histo ( 793) 4913 670.3 1.3e-191
NP_001269263 (OMIM: 601155) minor histocompatibili ( 771) 4908 669.6 2e-191
XP_006722776 (OMIM: 601155) PREDICTED: minor histo (1164) 4039 553.6 2.6e-156
XP_011526160 (OMIM: 601155) PREDICTED: minor histo (1168) 3855 529.0 6.5e-149
NP_001315595 (OMIM: 610496) rho GTPase-activating (1252) 1063 155.8 1.6e-36
XP_011540741 (OMIM: 610496) PREDICTED: rho GTPase- (1261) 1024 150.6 5.8e-35
NP_004806 (OMIM: 610496) rho GTPase-activating pro (1261) 1024 150.6 5.8e-35
NP_001315593 (OMIM: 610496) rho GTPase-activating (1261) 1024 150.6 5.8e-35
NP_001315594 (OMIM: 610496) rho GTPase-activating (1197) 986 145.5 1.9e-33
NP_001315596 (OMIM: 610496) rho GTPase-activating (1197) 986 145.5 1.9e-33
NP_001275928 (OMIM: 609694) GEM-interacting protei ( 944) 839 125.7 1.3e-27
XP_011526350 (OMIM: 609694) PREDICTED: GEM-interac ( 849) 833 124.9 2.1e-27
NP_001275927 (OMIM: 609694) GEM-interacting protei ( 941) 831 124.7 2.7e-27
XP_016882351 (OMIM: 609694) PREDICTED: GEM-interac ( 835) 829 124.4 3e-27
XP_016882350 (OMIM: 609694) PREDICTED: GEM-interac ( 884) 829 124.4 3.1e-27
NP_057657 (OMIM: 609694) GEM-interacting protein i ( 970) 829 124.4 3.3e-27
XP_005259984 (OMIM: 609694) PREDICTED: GEM-interac ( 967) 824 123.7 5.3e-27
XP_016880032 (OMIM: 600365) PREDICTED: active brea ( 660) 334 58.1 2.1e-07
XP_016880031 (OMIM: 600365) PREDICTED: active brea ( 663) 334 58.1 2.1e-07
XP_011522117 (OMIM: 600365) PREDICTED: active brea ( 832) 334 58.2 2.5e-07
XP_011522116 (OMIM: 600365) PREDICTED: active brea ( 832) 334 58.2 2.5e-07
XP_011522115 (OMIM: 600365) PREDICTED: active brea ( 841) 334 58.2 2.5e-07
XP_011522114 (OMIM: 600365) PREDICTED: active brea ( 865) 334 58.2 2.5e-07
XP_011522112 (OMIM: 600365) PREDICTED: active brea ( 878) 334 58.2 2.6e-07
XP_016880029 (OMIM: 600365) PREDICTED: active brea (1104) 334 58.3 3.1e-07
XP_016880028 (OMIM: 600365) PREDICTED: active brea (1137) 334 58.3 3.1e-07
XP_011519925 (OMIM: 604875) PREDICTED: unconventio (1737) 308 55.0 4.8e-06
XP_016877719 (OMIM: 604875) PREDICTED: unconventio (2547) 308 55.1 6.4e-06
NP_008832 (OMIM: 604875) unconventional myosin-IXa (2548) 308 55.1 6.4e-06
XP_011519924 (OMIM: 604875) PREDICTED: unconventio (2566) 308 55.1 6.5e-06
XP_016877718 (OMIM: 604875) PREDICTED: unconventio (2566) 308 55.1 6.5e-06
XP_011519923 (OMIM: 604875) PREDICTED: unconventio (2598) 308 55.1 6.5e-06
XP_011519922 (OMIM: 604875) PREDICTED: unconventio (2618) 308 55.1 6.6e-06
XP_011519921 (OMIM: 604875) PREDICTED: unconventio (2619) 308 55.1 6.6e-06
XP_006720602 (OMIM: 604875) PREDICTED: unconventio (2619) 308 55.1 6.6e-06
XP_016877717 (OMIM: 604875) PREDICTED: unconventio (2619) 308 55.1 6.6e-06
XP_011519920 (OMIM: 604875) PREDICTED: unconventio (2620) 308 55.1 6.6e-06
XP_011519919 (OMIM: 604875) PREDICTED: unconventio (2637) 308 55.1 6.6e-06
XP_011519915 (OMIM: 604875) PREDICTED: unconventio (2638) 308 55.1 6.6e-06
XP_011519917 (OMIM: 604875) PREDICTED: unconventio (2638) 308 55.1 6.6e-06
XP_011519916 (OMIM: 604875) PREDICTED: unconventio (2638) 308 55.1 6.6e-06
XP_011519918 (OMIM: 604875) PREDICTED: unconventio (2638) 308 55.1 6.6e-06
NP_001123537 (OMIM: 602129,609753) unconventional (2022) 289 52.5 3.1e-05
NP_004136 (OMIM: 602129,609753) unconventional myo (2157) 289 52.5 3.3e-05
NP_001306780 (OMIM: 610576) rho GTPase-activating ( 420) 268 49.1 6.6e-05
XP_016875291 (OMIM: 610576) PREDICTED: rho GTPase- ( 516) 268 49.2 7.7e-05
>>NP_036424 (OMIM: 601155) minor histocompatibility prot (1136 aa)
initn: 7490 init1: 7490 opt: 7490 Z-score: 5420.8 bits: 1014.9 E(85289): 0
Smith-Waterman score: 7490; 100.0% identity (100.0% similar) in 1136 aa overlap (1-1136:1-1136)
10 20 30 40 50 60
pF1KSD MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKAR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD FLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD EGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD RVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KSD TAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
1090 1100 1110 1120 1130
>>NP_001308161 (OMIM: 601155) minor histocompatibility p (1140 aa)
initn: 7291 init1: 7291 opt: 7306 Z-score: 5287.8 bits: 990.3 E(85289): 0
Smith-Waterman score: 7306; 98.8% identity (98.9% similar) in 1125 aa overlap (20-1136:16-1140)
10 20 30 40 50
pF1KSD MFSRKKRELMKTPSISKKNRAGSPSPQPSG--------ELPRKDGADAVFPGPSLEPPAG
::: .:: : ::::::::::::::::::::::
NP_001 MLGRRLGARASYSPYRAGRQGPQQRGRDPGIQLTELPRKDGADAVFPGPSLEPPAG
10 20 30 40 50
60 70 80 90 100 110
pF1KSD SSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD VEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD TVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD AVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD AKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGH
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD SMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD CEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVAD
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD AKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSK
480 490 500 510 520 530
540 550 560 570 580 590
pF1KSD LYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGS
540 550 560 570 580 590
600 610 620 630 640 650
pF1KSD PPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTM
600 610 620 630 640 650
660 670 680 690 700 710
pF1KSD SSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPA
660 670 680 690 700 710
720 730 740 750 760 770
pF1KSD KCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPD
720 730 740 750 760 770
780 790 800 810 820 830
pF1KSD GVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNV
780 790 800 810 820 830
840 850 860 870 880 890
pF1KSD LKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLR
840 850 860 870 880 890
900 910 920 930 940 950
pF1KSD ELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSS
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KSD LVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPL
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KSD QEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHS
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KSD GSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQ
1080 1090 1100 1110 1120 1130
pF1KSD PEFV
::::
NP_001 PEFV
1140
>>NP_001245257 (OMIM: 601155) minor histocompatibility p (1152 aa)
initn: 7305 init1: 7305 opt: 7305 Z-score: 5287.0 bits: 990.2 E(85289): 0
Smith-Waterman score: 7305; 99.7% identity (99.7% similar) in 1111 aa overlap (26-1136:42-1152)
10 20 30 40 50
pF1KSD MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSG
: : :::::::::::::::::::::::::
NP_001 LGWVCTWTWAWRARLGARGCGLHVLCPRDLPLPPEELPRKDGADAVFPGPSLEPPAGSSG
20 30 40 50 60 70
60 70 80 90 100 110
pF1KSD VKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVED
80 90 100 110 120 130
120 130 140 150 160 170
pF1KSD ISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVE
140 150 160 170 180 190
180 190 200 210 220 230
pF1KSD TLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVP
200 210 220 230 240 250
240 250 260 270 280 290
pF1KSD PGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKY
260 270 280 290 300 310
300 310 320 330 340 350
pF1KSD MKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMV
320 330 340 350 360 370
360 370 380 390 400 410
pF1KSD QAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCED
380 390 400 410 420 430
420 430 440 450 460 470
pF1KSD HDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKT
440 450 460 470 480 490
480 490 500 510 520 530
pF1KSD QKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYD
500 510 520 530 540 550
540 550 560 570 580 590
pF1KSD PGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPE
560 570 580 590 600 610
600 610 620 630 640 650
pF1KSD EGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSST
620 630 640 650 660 670
660 670 680 690 700 710
pF1KSD EELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCR
680 690 700 710 720 730
720 730 740 750 760 770
pF1KSD ECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVP
740 750 760 770 780 790
780 790 800 810 820 830
pF1KSD FIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKL
800 810 820 830 840 850
840 850 860 870 880 890
pF1KSD YLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELL
860 870 880 890 900 910
900 910 920 930 940 950
pF1KSD RDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVD
920 930 940 950 960 970
960 970 980 990 1000 1010
pF1KSD YPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEA
980 990 1000 1010 1020 1030
1020 1030 1040 1050 1060 1070
pF1KSD AADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSE
1040 1050 1060 1070 1080 1090
1080 1090 1100 1110 1120 1130
pF1KSD EQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEF
1100 1110 1120 1130 1140 1150
pF1KSD V
:
NP_001 V
>>NP_001269264 (OMIM: 601155) minor histocompatibility p (1019 aa)
initn: 6563 init1: 6563 opt: 6563 Z-score: 4751.7 bits: 890.9 E(85289): 0
Smith-Waterman score: 6563; 100.0% identity (100.0% similar) in 996 aa overlap (141-1136:24-1019)
120 130 140 150 160 170
pF1KSD DVVEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPL
::::::::::::::::::::::::::::::
NP_001 MCICGTAHPVLDEGPVRCRAGPRDLLEARRPRAHECLGEALRVMHQIISKYPL
10 20 30 40 50
180 190 200 210 220 230
pF1KSD LNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSST
60 70 80 90 100 110
240 250 260 270 280 290
pF1KSD LLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAK
120 130 140 150 160 170
300 310 320 330 340 350
pF1KSD NMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEF
180 190 200 210 220 230
360 370 380 390 400 410
pF1KSD GHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYV
240 250 260 270 280 290
420 430 440 450 460 470
pF1KSD QRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCV
300 310 320 330 340 350
480 490 500 510 520 530
pF1KSD ADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCES
360 370 380 390 400 410
540 550 560 570 580 590
pF1KSD SKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAA
420 430 440 450 460 470
600 610 620 630 640 650
pF1KSD GSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSG
480 490 500 510 520 530
660 670 680 690 700 710
pF1KSD TMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRT
540 550 560 570 580 590
720 730 740 750 760 770
pF1KSD PAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSA
600 610 620 630 640 650
780 790 800 810 820 830
pF1KSD PDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDIS
660 670 680 690 700 710
840 850 860 870 880 890
pF1KSD NVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGR
720 730 740 750 760 770
900 910 920 930 940 950
pF1KSD LRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSL
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KSD SSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVY
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KSD PLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGS
900 910 920 930 940 950
1080 1090 1100 1110 1120 1130
pF1KSD HSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRE
960 970 980 990 1000 1010
pF1KSD RQPEFV
::::::
NP_001 RQPEFV
>>XP_011526162 (OMIM: 601155) PREDICTED: minor histocomp (793 aa)
initn: 4909 init1: 4909 opt: 4913 Z-score: 3561.1 bits: 670.3 E(85289): 1.3e-191
Smith-Waterman score: 4913; 98.2% identity (99.1% similar) in 759 aa overlap (380-1136:35-793)
350 360 370 380 390 400
pF1KSD FGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIK-EAWHRA-QRKLQEAESNLRKAKQ
::. .. . : .: ..::::::::::::
XP_011 AGWAAPPNAKPGRRCSSPVAPSSAWKDPGARRSLLSLQKWGEAVPPSVQEAESNLRKAKQ
10 20 30 40 50 60
410 420 430 440 450 460
pF1KSD GYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYR
70 80 90 100 110 120
470 480 490 500 510 520
pF1KSD TCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQML
130 140 150 160 170 180
530 540 550 560 570 580
pF1KSD CESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARP
190 200 210 220 230 240
590 600 610 620 630 640
pF1KSD EAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTS
250 260 270 280 290 300
650 660 670 680 690 700
pF1KSD SSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRK
310 320 330 340 350 360
710 720 730 740 750 760
pF1KSD LRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAA
370 380 390 400 410 420
770 780 790 800 810 820
pF1KSD RSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPH
430 440 450 460 470 480
830 840 850 860 870 880
pF1KSD DISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVAL
490 500 510 520 530 540
890 900 910 920 930 940
pF1KSD AGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEAT
550 560 570 580 590 600
950 960 970 980 990 1000
pF1KSD VSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEA
610 620 630 640 650 660
1010 1020 1030 1040 1050 1060
pF1KSD VVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVA
670 680 690 700 710 720
1070 1080 1090 1100 1110 1120
pF1KSD SGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGS
730 740 750 760 770 780
1130
pF1KSD CRERQPEFV
:::::::::
XP_011 CRERQPEFV
790
>>NP_001269263 (OMIM: 601155) minor histocompatibility p (771 aa)
initn: 4908 init1: 4908 opt: 4908 Z-score: 3557.7 bits: 669.6 E(85289): 2e-191
Smith-Waterman score: 4908; 100.0% identity (100.0% similar) in 741 aa overlap (396-1136:31-771)
370 380 390 400 410 420
pF1KSD FMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAK
::::::::::::::::::::::::::::::
NP_001 MGVGRKGGAGETESHPRIGLELASWLPHPQQEAESNLRKAKQGYVQRCEDHDKARFLVAK
10 20 30 40 50 60
430 440 450 460 470 480
pF1KSD AEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKV
70 80 90 100 110 120
490 500 510 520 530 540
pF1KSD TALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVR
130 140 150 160 170 180
550 560 570 580 590 600
pF1KSD QLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPA
190 200 210 220 230 240
610 620 630 640 650 660
pF1KSD KDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGA
250 260 270 280 290 300
670 680 690 700 710 720
pF1KSD GASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQG
310 320 330 340 350 360
730 740 750 760 770 780
pF1KSD AECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEI
370 380 390 400 410 420
790 800 810 820 830 840
pF1KSD ERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLI
430 440 450 460 470 480
850 860 870 880 890 900
pF1KSD SFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRAS
490 500 510 520 530 540
910 920 930 940 950 960
pF1KSD LQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIET
550 560 570 580 590 600
970 980 990 1000 1010 1020
pF1KSD LIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRV
610 620 630 640 650 660
1030 1040 1050 1060 1070 1080
pF1KSD VSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATARED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATARED
670 680 690 700 710 720
1090 1100 1110 1120 1130
pF1KSD GDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
730 740 750 760 770
>>XP_006722776 (OMIM: 601155) PREDICTED: minor histocomp (1164 aa)
initn: 7476 init1: 4002 opt: 4039 Z-score: 2927.4 bits: 553.6 E(85289): 2.6e-156
Smith-Waterman score: 7424; 97.6% identity (97.6% similar) in 1164 aa overlap (1-1136:1-1164)
10 20 30 40 50 60
pF1KSD MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKAR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD FLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCT
550 560 570 580 590 600
610 620 630
pF1KSD EGTPAKDHR----------------------------AGRGHQVHKSWPLSISDSDSGLD
::::::::: :::::::::::::::::::::::
XP_006 EGTPAKDHRGECPAGPRGGRWLPATHPGPSPETPLSPAGRGHQVHKSWPLSISDSDSGLD
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD PGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD HEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAF
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD ENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD VFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQR
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD AEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHL
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KSD SFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAP
1090 1100 1110 1120 1130 1140
1120 1130
pF1KSD LPPMRLRGGRMTLGSCRERQPEFV
::::::::::::::::::::::::
XP_006 LPPMRLRGGRMTLGSCRERQPEFV
1150 1160
>>XP_011526160 (OMIM: 601155) PREDICTED: minor histocomp (1168 aa)
initn: 7277 init1: 3803 opt: 3855 Z-score: 2794.4 bits: 529.0 E(85289): 6.5e-149
Smith-Waterman score: 7240; 96.4% identity (96.5% similar) in 1153 aa overlap (20-1136:16-1168)
10 20 30 40 50
pF1KSD MFSRKKRELMKTPSISKKNRAGSPSPQPSG--------ELPRKDGADAVFPGPSLEPPAG
::: .:: : ::::::::::::::::::::::
XP_011 MLGRRLGARASYSPYRAGRQGPQQRGRDPGIQLTELPRKDGADAVFPGPSLEPPAG
10 20 30 40 50
60 70 80 90 100 110
pF1KSD SSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD VEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD TVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD AVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD AKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGH
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD SMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD CEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVAD
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD AKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSK
480 490 500 510 520 530
540 550 560 570 580 590
pF1KSD LYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGS
540 550 560 570 580 590
600 610 620
pF1KSD PPEEGGCTEGTPAKDHR----------------------------AGRGHQVHKSWPLSI
::::::::::::::::: :::::::::::::::
XP_011 PPEEGGCTEGTPAKDHRGECPAGPRGGRWLPATHPGPSPETPLSPAGRGHQVHKSWPLSI
600 610 620 630 640 650
630 640 650 660 670 680
pF1KSD SDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPV
660 670 680 690 700 710
690 700 710 720 730 740
pF1KSD AVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLA
720 730 740 750 760 770
750 760 770 780 790 800
pF1KSD IQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTR
780 790 800 810 820 830
810 820 830 840 850 860
pF1KSD VEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAE
840 850 860 870 880 890
870 880 890 900 910 920
pF1KSD AEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNK
900 910 920 930 940 950
930 940 950 960 970 980
pF1KSD MTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGG
960 970 980 990 1000 1010
990 1000 1010 1020 1030 1040
pF1KSD QDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSS
1020 1030 1040 1050 1060 1070
1050 1060 1070 1080 1090 1100
pF1KSD EASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQ
1080 1090 1100 1110 1120 1130
1110 1120 1130
pF1KSD SNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
::::::::::::::::::::::::::::::::
XP_011 SNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
1140 1150 1160
>>NP_001315595 (OMIM: 610496) rho GTPase-activating prot (1252 aa)
initn: 1914 init1: 745 opt: 1063 Z-score: 776.9 bits: 155.8 E(85289): 1.6e-36
Smith-Waterman score: 1989; 36.2% identity (65.7% similar) in 1033 aa overlap (110-1119:42-1007)
80 90 100 110 120 130
pF1KSD SGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLR
:: ... :. :. .:.. : ::: ..
NP_001 KRAWASGQLSTDITTSEMGLKSLSSNSIFDPDYIKE---LVNDIRKFSHMLLYLKEAIFS
20 30 40 50 60
140 150 160 170 180 190
pF1KSD DDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHY-----ES
: . :. : : : :::...:..:. ::.:. .:: : ::::: .. :.
NP_001 DCFKEV----IHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEVNEEN
70 80 90 100 110 120
200 210 220 230 240 250
pF1KSD NNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGT
.::: .. : ...::.: .:.. ...::::.: ...:: .: . ..:.:.. . :..
NP_001 KNDLFQEVF-SSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENV---SVESV
130 140 150 160 170 180
260 270 280 290 300 310
pF1KSD PPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFA
: : : . :.: .: . ... :: :::. .:: :...:..::. .::.: .
NP_001 DSSSE---KGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELEST
190 200 210 220 230
320 330 340 350 360 370
pF1KSD KGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRR
... :.:. : .. . ::: :... :: .:.: .: . :....::.. :.::: :.
NP_001 RNMVKLAEATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRK
240 250 260 270 280 290
380 390 400 410 420 430
pF1KSD LEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSA
: ::.:::::: :.. : :. :::. :.::: .:: ....::. . .::::. .:.
NP_001 NEMEKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSS
300 310 320 330 340 350
440 450 460 470 480 490
pF1KSD PGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEV
: ... .: :.:.::::::: .:.::: :..::.... ....::.:: : :.. .
NP_001 GGLAKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTL
360 370 380 390 400 410
500 510 520 530 540 550
pF1KSD IRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPD
. : : :.:. :.:.: : .: ::.:.:::::::.:. :. . .:
NP_001 VFQCDLTLKA---------HLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTEEEK
420 430 440 450 460
560 570 580 590 600 610
pF1KSD VHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGH
: . . :. :. .: . .:.. ::.: ... :: :.... :
NP_001 VDGNVNKHL--NSSQPSGFGPANSLE--DVVRLPDSSNKIEEDRCSNSADIT------GP
470 480 490 500 510
620 630 640 650 660
pF1KSD QVHKSWPLSI-SDSDS--------GLDP-GPGAGDF-KKFERTSSSGTMSSTEELVDPDG
. .:: ... :::.: .:: . . ::: .:. :: :::::::..
NP_001 SFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSAD-------
520 530 540 550 560 570
670 680 690 700 710 720
pF1KSD GAGASAFEQADLNGMTPELPVAV-PS--GPFRHEGLSKAARTHRLRKLRTPAKCRECNSY
::. : : . :. : :.. .:::: ::..::::.:.:::.:..
NP_001 ----------DLDEREPPSPSETGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGI
580 590 600 610 620
730 740 750 760 770 780
pF1KSD VYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKK
: :::.::::: :.::.::::.:.: :::.:: :...::: .:...:.. :::.:::.:
NP_001 VVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKI
630 640 650 660 670 680
790 800 810 820 830 840
pF1KSD CVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQL
:. ::: ::: .::::: : : ..::::::.::: .::..:. : ::: .:::::::::
NP_001 CASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQL
690 700 710 720 730 740
850 860 870 880 890
pF1KSD PEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGS-ESEAVAVA-LAGRLRELLRDL
:::.: ::::.:.. :::. ... : .. . . .: . . . . . . ..:::.:
NP_001 PEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQL
750 760 770 780 790 800
900 910 920 930 940 950
pF1KSD PPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPH
: : ::..:. ::.:.:. ..:::. :::..:::.:.::::: : ...:::..: .
NP_001 PASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSN
810 820 830 840 850 860
960 970 980 990 1000 1010
pF1KSD QARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAAD
:::..: ::.. .:. .: : .:. .. .. : :. :
NP_001 QARLVEFLITYSQKIFD------------GSLQPQDVMCSIGVVDQGCFPKPLLSPEERD
870 880 890 900
1020 1030 1040 1050 1060 1070
pF1KSD GCRESRVVSNDSDSDLEEASELLSSSEASALGH-LSFLEQQQSEASLEVASGSHSGSEEQ
: . . .: :.. : ::.. . . :: :..... .: .. : . .
NP_001 IERSMKSLFFSSKEDIHT-----SESESKIFERATSFEESERKQNALGKCDACLSDKAQL
910 920 930 940 950 960
1080 1090 1100 1110 1120 1130
pF1KSD L-EATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
: . :. .. ::: . . ......:.: .. : ..:
NP_001 LLDQEAESASQKIEDGKTPKPLSLKSDRSTNNVERHTPRTKIRPVSLPVDRLLLASPPNE
970 980 990 1000 1010 1020
NP_001 RNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNGFDQQTLQKIQDKQYEQNSLTAK
1030 1040 1050 1060 1070 1080
>>XP_011540741 (OMIM: 610496) PREDICTED: rho GTPase-acti (1261 aa)
initn: 1972 init1: 749 opt: 1024 Z-score: 748.7 bits: 150.6 E(85289): 5.8e-35
Smith-Waterman score: 2038; 36.4% identity (66.5% similar) in 1033 aa overlap (110-1119:42-1016)
80 90 100 110 120 130
pF1KSD SGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLR
:: ... :. :. .:.. : ::: ..
XP_011 KRAWASGQLSTDITTSEMGLKSLSSNSIFDPDYIKE---LVNDIRKFSHMLLYLKEAIFS
20 30 40 50 60
140 150 160 170 180 190
pF1KSD DDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHY-----ES
: . :. : : : :::...:..:. ::.:. .:: : ::::: .. :.
XP_011 DCFKEV----IHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEVNEEN
70 80 90 100 110 120
200 210 220 230 240 250
pF1KSD NNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGT
.::: .. : ...::.: .:.. ...::::.: ...:: .: . ..:.:.. . :..
XP_011 KNDLFQEVF-SSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENV---SVESV
130 140 150 160 170 180
260 270 280 290 300 310
pF1KSD PPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFA
: : : . :.: .: . ... :: :::. .:: :...:..::. .::.: .
XP_011 DSSSE---KGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELEST
190 200 210 220 230
320 330 340 350 360 370
pF1KSD KGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRR
... :.:. : .. . ::: :... :: .:.: .: . :....::.. :.::: :.
XP_011 RNMVKLAEATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRK
240 250 260 270 280 290
380 390 400 410 420 430
pF1KSD LEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSA
: ::.:::::: :.. : :. :::. :.::: .:: ....::. . .::::. .:.
XP_011 NEMEKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSS
300 310 320 330 340 350
440 450 460 470 480 490
pF1KSD PGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEV
: ... .: :.:.::::::: .:.::: :..::.... ....::.:: : :.. .
XP_011 GGLAKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTL
360 370 380 390 400 410
500 510 520 530 540 550
pF1KSD IRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPD
. : : :.:..:.. ..:.:.:.: : .: ::.:.:::::::.:. :. . .:
XP_011 VFQCDLTLKAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTEEEK
420 430 440 450 460 470
560 570 580 590 600 610
pF1KSD VHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGH
: . . :. :. .: . .:.. ::.: ... :: :.... :
XP_011 VDGNVNKHL--NSSQPSGFGPANSLE--DVVRLPDSSNKIEEDRCSNSADIT------GP
480 490 500 510 520
620 630 640 650 660
pF1KSD QVHKSWPLSI-SDSDS--------GLDP-GPGAGDF-KKFERTSSSGTMSSTEELVDPDG
. .:: ... :::.: .:: . . ::: .:. :: :::::::..
XP_011 SFIRSWTFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSAD-------
530 540 550 560 570 580
670 680 690 700 710 720
pF1KSD GAGASAFEQADLNGMTPELPVAV-PS--GPFRHEGLSKAARTHRLRKLRTPAKCRECNSY
::. : : . :. : :.. .:::: ::..::::.:.:::.:..
XP_011 ----------DLDEREPPSPSETGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGI
590 600 610 620 630
730 740 750 760 770 780
pF1KSD VYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKK
: :::.::::: :.::.::::.:.: :::.:: :...::: .:...:.. :::.:::.:
XP_011 VVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKI
640 650 660 670 680 690
790 800 810 820 830 840
pF1KSD CVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQL
:. ::: ::: .::::: : : ..::::::.::: .::..:. : ::: .:::::::::
XP_011 CASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQL
700 710 720 730 740 750
850 860 870 880 890
pF1KSD PEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGS-ESEAVAVA-LAGRLRELLRDL
:::.: ::::.:.. :::. ... : .. . . .: . . . . . . ..:::.:
XP_011 PEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQL
760 770 780 790 800 810
900 910 920 930 940 950
pF1KSD PPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPH
: : ::..:. ::.:.:. ..:::. :::..:::.:.::::: : ...:::..: .
XP_011 PASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSN
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KSD QARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAAD
:::..: ::.. .:. .: : .:. .. .. : :. :
XP_011 QARLVEFLITYSQKIFD------------GSLQPQDVMCSIGVVDQGCFPKPLLSPEERD
880 890 900 910
1020 1030 1040 1050 1060 1070
pF1KSD GCRESRVVSNDSDSDLEEASELLSSSEASALGH-LSFLEQQQSEASLEVASGSHSGSEEQ
: . . .: :.. : ::.. . . :: :..... .: .. : . .
XP_011 IERSMKSLFFSSKEDIHT-----SESESKIFERATSFEESERKQNALGKCDACLSDKAQL
920 930 940 950 960 970
1080 1090 1100 1110 1120 1130
pF1KSD L-EATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV
: . :. .. ::: . . ......:.: .. : ..:
XP_011 LLDQEAESASQKIEDGKTPKPLSLKSDRSTNNVERHTPRTKIRPVSLPVDRLLLASPPNE
980 990 1000 1010 1020 1030
XP_011 RNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNGFDQQTLQKIQDKQYEQNSLTAK
1040 1050 1060 1070 1080 1090
1136 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:47:10 2016 done: Thu Nov 3 00:47:12 2016
Total Scan time: 12.740 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]