FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0237, 308 aa 1>>>pF1KSDA0237 308 - 308 aa - 308 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5376+/-0.000318; mu= 14.9613+/- 0.020 mean_var=88.7846+/-18.116, 0's: 0 Z-trim(117.0): 236 B-trim: 0 in 0/53 Lambda= 0.136115 statistics sampled from 28322 (28594) to 28322 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.335), width: 16 Scan time: 8.030 The best scores are: opt bits E(85289) NP_055562 (OMIM: 611600) regulating synaptic membr ( 308) 1996 401.7 9.4e-112 XP_011540781 (OMIM: 611600) PREDICTED: regulating ( 312) 1545 313.2 4.4e-85 XP_006716761 (OMIM: 606630) PREDICTED: regulating ( 313) 1315 268.0 1.7e-71 XP_016869530 (OMIM: 606630) PREDICTED: regulating (1275) 1315 268.5 5e-71 XP_016869529 (OMIM: 606630) PREDICTED: regulating (1324) 1315 268.5 5.1e-71 XP_016869525 (OMIM: 606630) PREDICTED: regulating (1357) 1315 268.5 5.2e-71 XP_016869511 (OMIM: 606630) PREDICTED: regulating (1477) 1315 268.6 5.5e-71 XP_016869510 (OMIM: 606630) PREDICTED: regulating (1503) 1315 268.6 5.6e-71 XP_016869509 (OMIM: 606630) PREDICTED: regulating (1520) 1315 268.6 5.7e-71 XP_016869508 (OMIM: 606630) PREDICTED: regulating (1545) 1315 268.6 5.7e-71 XP_016869507 (OMIM: 606630) PREDICTED: regulating (1549) 1315 268.6 5.8e-71 XP_005251164 (OMIM: 606630) PREDICTED: regulating (1552) 1315 268.6 5.8e-71 XP_016869506 (OMIM: 606630) PREDICTED: regulating (1563) 1315 268.6 5.8e-71 XP_016869505 (OMIM: 606630) PREDICTED: regulating (1574) 1315 268.6 5.8e-71 XP_005251163 (OMIM: 606630) PREDICTED: regulating (1574) 1315 268.6 5.8e-71 XP_016869504 (OMIM: 606630) PREDICTED: regulating (1579) 1315 268.6 5.8e-71 XP_016869503 (OMIM: 606630) PREDICTED: regulating (1589) 1315 268.6 5.9e-71 XP_016869502 (OMIM: 606630) PREDICTED: regulating (1607) 1315 268.6 5.9e-71 XP_016869501 (OMIM: 606630) PREDICTED: regulating (1610) 1315 268.6 5.9e-71 XP_016869500 (OMIM: 606630) PREDICTED: regulating (1621) 1315 268.6 6e-71 XP_016869499 (OMIM: 606630) PREDICTED: regulating (1625) 1315 268.6 6e-71 XP_016869498 (OMIM: 606630) PREDICTED: regulating (1637) 1315 268.6 6e-71 XP_016869497 (OMIM: 606630) PREDICTED: regulating (1672) 1315 268.6 6.1e-71 XP_016869496 (OMIM: 606630) PREDICTED: regulating (1675) 1315 268.6 6.1e-71 XP_016869495 (OMIM: 606630) PREDICTED: regulating (1705) 1315 268.6 6.2e-71 XP_011515697 (OMIM: 606630) PREDICTED: regulating (1710) 1315 268.6 6.2e-71 XP_016866046 (OMIM: 603649,606629) PREDICTED: regu ( 342) 1295 264.1 2.8e-70 XP_016866047 (OMIM: 603649,606629) PREDICTED: regu ( 342) 1295 264.1 2.8e-70 XP_016866045 (OMIM: 603649,606629) PREDICTED: regu ( 398) 1291 263.4 5.4e-70 XP_016866038 (OMIM: 603649,606629) PREDICTED: regu ( 937) 1291 263.7 1e-69 XP_016866037 (OMIM: 603649,606629) PREDICTED: regu ( 938) 1291 263.7 1e-69 XP_016866036 (OMIM: 603649,606629) PREDICTED: regu ( 979) 1291 263.7 1.1e-69 XP_016866035 (OMIM: 603649,606629) PREDICTED: regu ( 980) 1291 263.7 1.1e-69 XP_016866034 (OMIM: 603649,606629) PREDICTED: regu ( 982) 1291 263.7 1.1e-69 XP_016866032 (OMIM: 603649,606629) PREDICTED: regu ( 988) 1291 263.7 1.1e-69 XP_016866033 (OMIM: 603649,606629) PREDICTED: regu ( 988) 1291 263.7 1.1e-69 XP_016866031 (OMIM: 603649,606629) PREDICTED: regu ( 989) 1291 263.7 1.1e-69 XP_016866030 (OMIM: 603649,606629) PREDICTED: regu ( 998) 1291 263.7 1.1e-69 XP_016866029 (OMIM: 603649,606629) PREDICTED: regu ( 999) 1291 263.7 1.1e-69 NP_001161879 (OMIM: 603649,606629) regulating syna (1012) 1291 263.7 1.1e-69 XP_016866028 (OMIM: 603649,606629) PREDICTED: regu (1013) 1291 263.7 1.1e-69 XP_016866027 (OMIM: 603649,606629) PREDICTED: regu (1014) 1291 263.7 1.1e-69 XP_016866026 (OMIM: 603649,606629) PREDICTED: regu (1040) 1291 263.7 1.1e-69 XP_016866025 (OMIM: 603649,606629) PREDICTED: regu (1044) 1291 263.7 1.1e-69 XP_016866024 (OMIM: 603649,606629) PREDICTED: regu (1073) 1291 263.7 1.1e-69 XP_016866023 (OMIM: 603649,606629) PREDICTED: regu (1074) 1291 263.7 1.1e-69 XP_011533913 (OMIM: 603649,606629) PREDICTED: regu (1463) 1291 263.8 1.4e-69 XP_016866018 (OMIM: 603649,606629) PREDICTED: regu (1464) 1291 263.8 1.4e-69 XP_016866017 (OMIM: 603649,606629) PREDICTED: regu (1473) 1291 263.8 1.5e-69 XP_016866016 (OMIM: 603649,606629) PREDICTED: regu (1514) 1291 263.9 1.5e-69 >>NP_055562 (OMIM: 611600) regulating synaptic membrane (308 aa) initn: 1996 init1: 1996 opt: 1996 Z-score: 2127.3 bits: 401.7 E(85289): 9.4e-112 Smith-Waterman score: 1996; 99.7% identity (100.0% similar) in 308 aa overlap (1-308:1-308) 10 20 30 40 50 60 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_055 MFNGEPGPASSGASRNVVRSSSISGEICGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQGKVLQVI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLE 250 260 270 280 290 300 pF1KSD SATSPSCS :::::::: NP_055 SATSPSCS >>XP_011540781 (OMIM: 611600) PREDICTED: regulating syna (312 aa) initn: 1545 init1: 1545 opt: 1545 Z-score: 1648.6 bits: 313.2 E(85289): 4.4e-85 Smith-Waterman score: 1545; 98.8% identity (99.2% similar) in 241 aa overlap (68-308:72-312) 40 50 60 70 80 90 pF1KSD GTTTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRS :. : ::::::::::::::::::::::::: XP_011 CFGRSQLKPCANALGVCCWEAAPCDAEHQAQIHQFEGATKKLRSNIRRSTETGIAVEMRS 50 60 70 80 90 100 100 110 120 130 140 150 pF1KSD RVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPM 110 120 130 140 150 160 160 170 180 190 200 210 pF1KSD GDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKT 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD CDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLF 230 240 250 260 270 280 280 290 300 pF1KSD PTSSVADSTLGSLTRRLSQSSLESATSPSCS ::::::::::::::::::::::::::::::: XP_011 PTSSVADSTLGSLTRRLSQSSLESATSPSCS 290 300 310 >>XP_006716761 (OMIM: 606630) PREDICTED: regulating syna (313 aa) initn: 1290 init1: 1265 opt: 1315 Z-score: 1404.5 bits: 268.0 E(85289): 1.7e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:9-311) 10 20 30 40 50 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----AGT--TTAKKRRSSLGAKM ...:...:.::.:..:. .. :. .:: :..::::::::::: XP_006 MQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAVGTLGTSGKKRRSSLGAKM 10 20 30 40 50 60 70 80 90 100 110 pF1KSD VAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTN ::::::.. :.:. :: : :.. :::::...::::::.:::::. .:::.:::::::: : XP_006 VAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEV : ::.:..::: .::...::::::::::::::.::::::::: :::.....::..::::: XP_006 SYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD EVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQ :.:.::::. :::::.::: :.:::::.::.:.::::::...:: .::::: : :.:.:: XP_006 EIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD GKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRR :::::.:::::::::::: :::.:::.::::.:: : ::.:::: ::..: ::. :::: XP_006 GKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRR 240 250 260 270 280 290 300 pF1KSD LSQSSLESATSPSCS :::::::.:.:: : XP_006 ASQSSLESSTGPSYSRS 300 310 >>XP_016869530 (OMIM: 606630) PREDICTED: regulating syna (1275 aa) initn: 1321 init1: 1265 opt: 1315 Z-score: 1396.2 bits: 268.5 E(85289): 5e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:971-1273) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 950 960 970 980 990 1000 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1010 1020 1030 1040 1050 1060 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1070 1080 1090 1100 1110 1120 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1130 1140 1150 1160 1170 1180 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1190 1200 1210 1220 1230 1240 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1250 1260 1270 >>XP_016869529 (OMIM: 606630) PREDICTED: regulating syna (1324 aa) initn: 1302 init1: 1265 opt: 1315 Z-score: 1396.0 bits: 268.5 E(85289): 5.1e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1020-1322) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 990 1000 1010 1020 1030 1040 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1050 1060 1070 1080 1090 1100 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1110 1120 1130 1140 1150 1160 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1170 1180 1190 1200 1210 1220 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1230 1240 1250 1260 1270 1280 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1290 1300 1310 1320 >>XP_016869525 (OMIM: 606630) PREDICTED: regulating syna (1357 aa) initn: 1321 init1: 1265 opt: 1315 Z-score: 1395.8 bits: 268.5 E(85289): 5.2e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1053-1355) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 1030 1040 1050 1060 1070 1080 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1090 1100 1110 1120 1130 1140 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1150 1160 1170 1180 1190 1200 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1210 1220 1230 1240 1250 1260 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1270 1280 1290 1300 1310 1320 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1330 1340 1350 >>XP_016869511 (OMIM: 606630) PREDICTED: regulating syna (1477 aa) initn: 1302 init1: 1265 opt: 1315 Z-score: 1395.3 bits: 268.6 E(85289): 5.5e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1173-1475) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 QWNKEDLQRRFSQDDTSVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 1150 1160 1170 1180 1190 1200 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1210 1220 1230 1240 1250 1260 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1270 1280 1290 1300 1310 1320 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1330 1340 1350 1360 1370 1380 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1390 1400 1410 1420 1430 1440 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1450 1460 1470 >>XP_016869510 (OMIM: 606630) PREDICTED: regulating syna (1503 aa) initn: 1302 init1: 1265 opt: 1315 Z-score: 1395.2 bits: 268.6 E(85289): 5.6e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1199-1501) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 1170 1180 1190 1200 1210 1220 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1230 1240 1250 1260 1270 1280 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1290 1300 1310 1320 1330 1340 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1350 1360 1370 1380 1390 1400 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1410 1420 1430 1440 1450 1460 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1470 1480 1490 1500 >>XP_016869509 (OMIM: 606630) PREDICTED: regulating syna (1520 aa) initn: 1302 init1: 1265 opt: 1315 Z-score: 1395.2 bits: 268.6 E(85289): 5.7e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1216-1518) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 1190 1200 1210 1220 1230 1240 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1250 1260 1270 1280 1290 1300 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1310 1320 1330 1340 1350 1360 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1370 1380 1390 1400 1410 1420 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1430 1440 1450 1460 1470 1480 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1490 1500 1510 1520 >>XP_016869508 (OMIM: 606630) PREDICTED: regulating syna (1545 aa) initn: 1302 init1: 1265 opt: 1315 Z-score: 1395.1 bits: 268.6 E(85289): 5.7e-71 Smith-Waterman score: 1315; 66.0% identity (88.8% similar) in 303 aa overlap (13-308:1241-1543) 10 20 30 pF1KSD MFNGEPGPASSGASRNVVRSSSIGGEICGSQQAGGG-----A ...:...:.::.:..:. .. :. . XP_016 SYMSVQSERPGGNKKISVFTSKMQSRQMGISGKNMTKSTSISGDMCSLEKNDGSQSDTAV 1220 1230 1240 1250 1260 1270 40 50 60 70 80 90 pF1KSD GT--TTAKKRRSSLGAKMVAIVGLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEM :: :..:::::::::::::::::.. :.:. :: : :.. :::::...::::::.:::: XP_016 GTLGTSGKKRRSSLGAKMVAIVGLSRKSRSASQLSQTEAGGKKLRSTVQRSTETGLAVEM 1280 1290 1300 1310 1320 1330 100 110 120 130 140 150 pF1KSD RSRVTRQGSRESTDGSTNSNSSDGTFIFPTTRLGAESQFSDFLDGLGPAQIVGRQTLATP :. .:::.:::::::: :: ::.:..::: .::...::::::::::::::.::::::::: XP_016 RNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATP 1340 1350 1360 1370 1380 1390 160 170 180 190 200 210 pF1KSD PMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKVYLLENGACLAKKKTKMTK :::.....::..::::::.:.::::. :::::.::: :.:::::.::.:.::::::... XP_016 AMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVAR 1400 1410 1420 1430 1440 1450 220 230 240 250 260 270 pF1KSD KTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYK :: .::::: : :.:.:::::::.:::::::::::: :::.:::.::::.:: : ::.: XP_016 KTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFK 1460 1470 1480 1490 1500 1510 280 290 300 pF1KSD LFPTSSVADSTLGSLTRRLSQSSLESATSPSCS ::: ::..: ::. :::: :::::::.:.:: : XP_016 LFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1520 1530 1540 308 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:50:58 2016 done: Thu Nov 3 00:50:59 2016 Total Scan time: 8.030 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]