Result of FASTA (omim) for
pF1KSDA0239
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0239, 790 aa
1>>>pF1KSDA0239 790 - 790 aa - 790 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.6179+/-0.000402; mu= -12.1334+/- 0.025
mean_var=444.1440+/-92.716, 0's: 0 Z-trim(123.7): 90 B-trim: 0 in 0/62
Lambda= 0.060857
statistics sampled from 43975 (44072) to 43975 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.517), width: 16
Scan time: 11.410
The best scores are: opt bits E(85289)
NP_056103 (OMIM: 610515) protein Jade-2 isoform 3 ( 790) 5477 495.6 3.5e-139
NP_001276913 (OMIM: 610515) protein Jade-2 isoform ( 791) 5465 494.5 7.2e-139
XP_016864771 (OMIM: 610515) PREDICTED: protein Jad ( 833) 3581 329.1 4.7e-89
XP_005272005 (OMIM: 610515) PREDICTED: protein Jad ( 834) 3581 329.1 4.7e-89
NP_001295072 (OMIM: 610515) protein Jade-2 isoform ( 834) 3581 329.1 4.7e-89
XP_005272003 (OMIM: 610515) PREDICTED: protein Jad ( 834) 3581 329.1 4.7e-89
XP_005272002 (OMIM: 610515) PREDICTED: protein Jad ( 834) 3581 329.1 4.7e-89
XP_011541593 (OMIM: 610515) PREDICTED: protein Jad ( 834) 3581 329.1 4.7e-89
NP_001276914 (OMIM: 610515) protein Jade-2 isoform ( 850) 3581 329.1 4.7e-89
NP_001070913 (OMIM: 300618) protein Jade-3 [Homo s ( 823) 1810 173.6 3e-42
NP_055550 (OMIM: 300618) protein Jade-3 [Homo sapi ( 823) 1810 173.6 3e-42
NP_001274366 (OMIM: 610514) protein Jade-1 isoform ( 830) 1707 164.6 1.6e-39
NP_001274370 (OMIM: 610514) protein Jade-1 isoform ( 509) 1372 135.0 7.8e-31
NP_079176 (OMIM: 610514) protein Jade-1 isoform 2 ( 509) 1372 135.0 7.8e-31
XP_016864116 (OMIM: 610514) PREDICTED: protein Jad ( 529) 1372 135.0 8e-31
XP_016864115 (OMIM: 610514) PREDICTED: protein Jad ( 529) 1372 135.0 8e-31
NP_001274368 (OMIM: 610514) protein Jade-1 isoform ( 842) 1372 135.2 1.1e-30
XP_005263289 (OMIM: 610514) PREDICTED: protein Jad ( 842) 1372 135.2 1.1e-30
NP_001274369 (OMIM: 610514) protein Jade-1 isoform ( 842) 1372 135.2 1.1e-30
NP_001274372 (OMIM: 610514) protein Jade-1 isoform ( 842) 1372 135.2 1.1e-30
NP_955352 (OMIM: 610514) protein Jade-1 isoform 1 ( 842) 1372 135.2 1.1e-30
NP_001274371 (OMIM: 610514) protein Jade-1 isoform ( 842) 1372 135.2 1.1e-30
XP_016884210 (OMIM: 604589) PREDICTED: bromodomain ( 941) 694 75.7 1e-12
XP_016884209 (OMIM: 604589) PREDICTED: bromodomain ( 955) 694 75.7 1e-12
XP_016884208 (OMIM: 604589) PREDICTED: bromodomain ( 958) 694 75.7 1e-12
XP_016884207 (OMIM: 604589) PREDICTED: bromodomain (1023) 694 75.7 1.1e-12
NP_001291738 (OMIM: 604589) bromodomain-containing (1058) 694 75.7 1.1e-12
XP_016884203 (OMIM: 604589) PREDICTED: bromodomain (1187) 694 75.8 1.2e-12
NP_001291737 (OMIM: 604589) bromodomain-containing (1189) 694 75.8 1.2e-12
XP_016884204 (OMIM: 604589) PREDICTED: bromodomain (1189) 694 75.8 1.2e-12
XP_016884206 (OMIM: 604589) PREDICTED: bromodomain (1189) 694 75.8 1.2e-12
XP_016884205 (OMIM: 604589) PREDICTED: bromodomain (1189) 694 75.8 1.2e-12
NP_001305978 (OMIM: 602410) peregrin isoform 3 [Ho (1119) 643 71.3 2.6e-11
XP_005265509 (OMIM: 602410) PREDICTED: peregrin is (1125) 643 71.3 2.6e-11
NP_001305979 (OMIM: 602410) peregrin isoform 4 [Ho (1213) 643 71.3 2.8e-11
NP_004625 (OMIM: 602410) peregrin isoform 2 [Homo (1214) 643 71.3 2.8e-11
XP_005265507 (OMIM: 602410) PREDICTED: peregrin is (1219) 643 71.3 2.8e-11
NP_001003694 (OMIM: 602410) peregrin isoform 1 [Ho (1220) 643 71.3 2.8e-11
XP_005265506 (OMIM: 602410) PREDICTED: peregrin is (1247) 643 71.3 2.9e-11
XP_011532403 (OMIM: 602410) PREDICTED: peregrin is (1248) 643 71.3 2.9e-11
XP_011532404 (OMIM: 602410) PREDICTED: peregrin is (1248) 643 71.3 2.9e-11
XP_011512794 (OMIM: 616856) PREDICTED: bromodomain ( 832) 623 69.4 7.1e-11
XP_016866231 (OMIM: 616856) PREDICTED: bromodomain (1088) 623 69.5 8.7e-11
XP_011512793 (OMIM: 616856) PREDICTED: bromodomain (1131) 623 69.5 8.9e-11
XP_011512792 (OMIM: 616856) PREDICTED: bromodomain (1144) 623 69.5 9e-11
XP_005249067 (OMIM: 616856) PREDICTED: bromodomain (1205) 623 69.6 9.4e-11
XP_011512791 (OMIM: 616856) PREDICTED: bromodomain (1205) 623 69.6 9.4e-11
NP_056510 (OMIM: 616856) bromodomain and PHD finge (1205) 623 69.6 9.4e-11
XP_005249068 (OMIM: 616856) PREDICTED: bromodomain (1205) 623 69.6 9.4e-11
XP_016880139 (OMIM: 600328) PREDICTED: protein AF- ( 652) 492 57.8 1.7e-07
>>NP_056103 (OMIM: 610515) protein Jade-2 isoform 3 [Hom (790 aa)
initn: 5477 init1: 5477 opt: 5477 Z-score: 2619.8 bits: 495.6 E(85289): 3.5e-139
Smith-Waterman score: 5477; 99.9% identity (99.9% similar) in 790 aa overlap (1-790:1-790)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_056 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRGLSTSFPIDGTFFNSWLAQSVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRGLSTSFPIDGTFFNSWLAQSVQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD TAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD PGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAE
730 740 750 760 770 780
790
pF1KSD EVVRMGVLAS
::::::::::
NP_056 EVVRMGVLAS
790
>>NP_001276913 (OMIM: 610515) protein Jade-2 isoform 1 [ (791 aa)
initn: 5463 init1: 3581 opt: 5465 Z-score: 2614.1 bits: 494.5 E(85289): 7.2e-139
Smith-Waterman score: 5465; 99.7% identity (99.7% similar) in 791 aa overlap (1-790:1-791)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510 520 530
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-GLSTSFPIDGTFFNSWLAQSVQ
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRAGLSTSFPIDGTFFNSWLAQSVQ
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD ITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD AAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRR
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD LPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGA
730 740 750 760 770 780
780 790
pF1KSD EEVVRMGVLAS
:::::::::::
NP_001 EEVVRMGVLAS
790
>>XP_016864771 (OMIM: 610515) PREDICTED: protein Jade-2 (833 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5317; 94.6% identity (94.6% similar) in 822 aa overlap (1-779:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
XP_016 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD --------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHR
::::::::::::::::::::::::::::::::::::::::
XP_016 GSTEKKEKVKAGPDSVLGQLGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHR
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD EDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGS
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD RTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLA
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD PETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAE
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD RPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
XP_016 RPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>XP_005272005 (OMIM: 610515) PREDICTED: protein Jade-2 (834 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_005 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
XP_005 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD ---------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
:::::::::::::::::::::::::::::::::::::::
XP_005 GSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
XP_005 ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>NP_001295072 (OMIM: 610515) protein Jade-2 isoform 4 [ (834 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
NP_001 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD ---------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
:::::::::::::::::::::::::::::::::::::::
NP_001 GSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>XP_005272003 (OMIM: 610515) PREDICTED: protein Jade-2 (834 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_005 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
XP_005 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD ---------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
:::::::::::::::::::::::::::::::::::::::
XP_005 GSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
XP_005 ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>XP_005272002 (OMIM: 610515) PREDICTED: protein Jade-2 (834 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_005 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
XP_005 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD ---------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
:::::::::::::::::::::::::::::::::::::::
XP_005 GSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
XP_005 ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>XP_011541593 (OMIM: 610515) PREDICTED: protein Jade-2 (834 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.8 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:1-822)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD HIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILADNDEVKFKSF
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 HIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVR
430 440 450 460 470 480
490 500 510
pF1KSD NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-----------------------
:::::::::::::::::::::::::::::::::::::
XP_011 NLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRAKGKKSDSKRKGCEGSK
490 500 510 520 530 540
520 530 540 550
pF1KSD ---------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
:::::::::::::::::::::::::::::::::::::::
XP_011 GSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGH
550 560 570 580 590 600
560 570 580 590 600 610
pF1KSD REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPG
610 620 630 640 650 660
620 630 640 650 660 670
pF1KSD SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KSD APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVA
730 740 750 760 770 780
740 750 760 770 780 790
pF1KSD ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
::::::::::::::::::::::::::::::::::::::::::
XP_011 ERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
790 800 810 820 830
>>NP_001276914 (OMIM: 610515) protein Jade-2 isoform 2 [ (850 aa)
initn: 5463 init1: 3581 opt: 3581 Z-score: 1719.7 bits: 329.1 E(85289): 4.7e-89
Smith-Waterman score: 5310; 94.5% identity (94.5% similar) in 822 aa overlap (1-778:17-838)
10 20 30 40
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVPTAAIAVGGYFLGGMEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD NEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD ILPPLEGPPAQASPSSTMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPPLEGPPAQASPSSTMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD LTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD CVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPE
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD VSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 VSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD MRTILADNDEVKFKSFCQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRTILADNDEVKFKSFCQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDF
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD YELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYR
430 440 450 460 470 480
470 480 490 500 510
pF1KSD RLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRRA
490 500 510 520 530 540
520 530 540
pF1KSD -------------------------------------GLSTSFPIDGTFFNSWLAQSVQI
:::::::::::::::::::::::
NP_001 KGKKSDSKRKGCEGSKGSTEKKEKVKAGPDSVLGQLAGLSTSFPIDGTFFNSWLAQSVQI
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD TAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRL
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD PAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPA
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD AGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRL
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD PGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAE
790 800 810 820 830 840
790
pF1KSD EVVRMGVLAS
NP_001 EVVRMGVLAS
850
>>NP_001070913 (OMIM: 300618) protein Jade-3 [Homo sapie (823 aa)
initn: 2148 init1: 1273 opt: 1810 Z-score: 879.6 bits: 173.6 E(85289): 3e-42
Smith-Waterman score: 2078; 43.6% identity (67.4% similar) in 803 aa overlap (4-772:2-786)
10 20 30 40 50 60
pF1KSD MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITA
::.. :::.:: .: .:: ... .. :: : .. :::.:::: :::.:
NP_001 MKRHRPVSSSDSSD--ESPSTSFTSGSMYRI----KSKIPNEH-KKPAEVFRKDLISA
10 20 30 40 50
70 80 90 100 110
pF1KSD MKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPP-----LEGPPAQ
::.:::....::.::..:: :..::::::::::. ...:.: .::. : : .
NP_001 MKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD ----ASPSSTMLGEGSQPDWPGG-SRYDLDEIDAYWLELINSELKEMERPELDELTLERV
.::..: : . . .. :::::..: .::. .: .: :: .:: .:..
NP_001 YIHCSSPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD LEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQAC
.: :: ::.:: .::::.:::::::::::.:::::::..:.::.:::::::::::::::
NP_001 VEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQAC
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD YGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCP
::::::: ::::::.:.::. :.:.::::.::::: :..::::.:::::::::::::.::
NP_001 YGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD EKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVIAFHVTCAFDHGLEMRTILA
:.::::::::::: ::::: :.::: ::.:::::. ::. ::::::::.:::::.:::
NP_001 ERMEPITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILD
300 310 320 330 340 350
360 370 380 390 400
pF1KSD DNDEVKFKSFCQEHSDG----GPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYE
..:::::::.: .::.. : . : . : ::: ::..:: :.:..:::.::
NP_001 EGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKS--EKTSLRAQKLRELEEEFYS
360 370 380 390 400
410 420 430 440 450 460
pF1KSD LVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRL
::. .:: .: . :::::.:::::::.: :.::. :: :: ..:.: ... .. :.
NP_001 LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRM
410 420 430 440 450 460
470 480 490 500 510 520
pF1KSD KLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRGLSTSFPID
..: :::::::::::::::..:::. : . :.::::: ::..:..:.. :: . ..
NP_001 RMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALE
470 480 490 500 510 520
530 540 550 560 570
pF1KSD GTFFNSWLAQSVQI-----TAENMAMSEWPLNNG-HREDPAPGLLSEELLQ-DEETLL--
...: .... : :. : .. : : . .. : . .: .:.:
NP_001 NSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
530 540 550 560 570 580
580 590 600 610 620 630
pF1KSD --SFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGSRTTPDKA-PKKTWGQDAG
:. : : .. . ...: ::.. : :.:. .. : : :
NP_001 TKSYPRYPLESKNNRLLASLSHSRSEAKESS---PAWRTPSSECYHGQSLGKPLVLQAAL
590 600 610 620 630 640
640 650 660 670 680 690
pF1KSD SGKGGQGPPTRKPPRR--TSSHLPSSPAAGDCPILATPESPPPLAPETPDEAASVAADSD
:... : .: . :. : .: .:. . : . . : . ......
NP_001 HGQSSIGNGKSQPNSKFAKSNGLEGS-WSGN--VTQKDSSSEMFCDQEPVFSPHLVSQGS
650 660 670 680 690 700
700 710 720 730 740
pF1KSD VQVPGPAASPKPLGRLRPPRESKVTRRLPG-ARPDAGMGPPSA-----VAERPKVSLHFD
. . . . : : :. : ..: .:.: : .: ..
NP_001 FRKSTVEHFSRSF-KETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQ
710 720 730 740 750 760
750 760 770 780 790
pF1KSD TETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS
:.::: : :.:::..:. ::. ..
NP_001 -ENDGYCPDLELSDSEAES-DGNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSS
770 780 790 800 810 820
790 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:52:55 2016 done: Thu Nov 3 00:52:57 2016
Total Scan time: 11.410 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]