FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0245, 515 aa 1>>>pF1KSDA0245 515 - 515 aa - 515 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6422+/-0.000402; mu= 22.1718+/- 0.025 mean_var=64.6838+/-13.101, 0's: 0 Z-trim(110.7): 62 B-trim: 1107 in 1/53 Lambda= 0.159469 statistics sampled from 18993 (19059) to 18993 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.223), width: 16 Scan time: 7.840 The best scores are: opt bits E(85289) XP_011521736 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 3394 790.1 0 XP_011521735 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 3394 790.1 0 NP_001070253 (OMIM: 605641) Y+L amino acid transpo ( 515) 3394 790.1 0 NP_003974 (OMIM: 605641) Y+L amino acid transporte ( 515) 3394 790.1 0 XP_011521740 (OMIM: 605641) PREDICTED: Y+L amino a ( 515) 3394 790.1 0 XP_006720365 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 2522 589.5 8e-168 NP_001119577 (OMIM: 222700,603593) Y+L amino acid ( 511) 2522 589.5 8e-168 XP_011535600 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 2522 589.5 8e-168 NP_001119578 (OMIM: 222700,603593) Y+L amino acid ( 511) 2522 589.5 8e-168 XP_011535601 (OMIM: 222700,603593) PREDICTED: Y+L ( 511) 2522 589.5 8e-168 XP_016879340 (OMIM: 605641) PREDICTED: Y+L amino a ( 382) 2245 525.6 9.9e-149 XP_011521741 (OMIM: 605641) PREDICTED: Y+L amino a ( 307) 2036 477.5 2.5e-134 NP_036376 (OMIM: 604235) large neutral amino acids ( 535) 1665 392.3 1.9e-108 NP_003477 (OMIM: 600182) large neutral amino acids ( 507) 1621 382.2 2e-105 XP_016879224 (OMIM: 600182) PREDICTED: large neutr ( 509) 1621 382.2 2e-105 NP_062823 (OMIM: 607959) asc-type amino acid trans ( 523) 1544 364.5 4.4e-100 NP_055146 (OMIM: 607933) cystine/glutamate transpo ( 501) 1509 356.4 1.1e-97 XP_011530104 (OMIM: 607933) PREDICTED: cystine/glu ( 506) 1494 353.0 1.3e-96 NP_001119807 (OMIM: 220100,604144) B(0,+)-type ami ( 487) 1365 323.3 1e-87 NP_001229965 (OMIM: 220100,604144) B(0,+)-type ami ( 487) 1365 323.3 1e-87 XP_011524704 (OMIM: 220100,604144) PREDICTED: B(0, ( 487) 1365 323.3 1e-87 NP_055085 (OMIM: 220100,604144) B(0,+)-type amino ( 487) 1365 323.3 1e-87 XP_006723347 (OMIM: 607959) PREDICTED: asc-type am ( 444) 1102 262.7 1.6e-69 XP_016881719 (OMIM: 220100,604144) PREDICTED: B(0, ( 399) 1092 260.4 7.3e-69 NP_001253965 (OMIM: 604235) large neutral amino ac ( 430) 1086 259.0 2e-68 XP_016879226 (OMIM: 600182) PREDICTED: large neutr ( 332) 1061 253.2 8.9e-67 XP_006721349 (OMIM: 600182) PREDICTED: large neutr ( 352) 1061 253.2 9.3e-67 XP_011525421 (OMIM: 607959) PREDICTED: asc-type am ( 660) 968 232.0 4.1e-60 NP_877392 (OMIM: 604235) large neutral amino acids ( 332) 952 228.1 3.2e-59 XP_016879225 (OMIM: 600182) PREDICTED: large neutr ( 467) 940 225.5 2.8e-58 NP_001253966 (OMIM: 604235) large neutral amino ac ( 311) 809 195.2 2.4e-49 XP_006723055 (OMIM: 220100,604144) PREDICTED: B(0, ( 260) 654 159.4 1.1e-38 XP_011525422 (OMIM: 607959) PREDICTED: asc-type am ( 633) 451 113.1 2.5e-24 NP_004164 (OMIM: 603752) cationic amino acid trans ( 635) 193 53.7 1.9e-06 XP_005266564 (OMIM: 104615) PREDICTED: high affini ( 629) 192 53.5 2.2e-06 NP_003036 (OMIM: 104615) high affinity cationic am ( 629) 192 53.5 2.2e-06 XP_016876205 (OMIM: 104615) PREDICTED: high affini ( 629) 192 53.5 2.2e-06 XP_016876203 (OMIM: 104615) PREDICTED: high affini ( 643) 192 53.5 2.2e-06 XP_016876202 (OMIM: 104615) PREDICTED: high affini ( 643) 192 53.5 2.2e-06 XP_016876204 (OMIM: 104615) PREDICTED: high affini ( 643) 192 53.5 2.2e-06 XP_016869236 (OMIM: 601872) PREDICTED: cationic am ( 657) 184 51.7 8.1e-06 NP_001008539 (OMIM: 601872) cationic amino acid tr ( 658) 184 51.7 8.1e-06 XP_005273667 (OMIM: 601872) PREDICTED: cationic am ( 658) 184 51.7 8.1e-06 XP_005273668 (OMIM: 601872) PREDICTED: cationic am ( 658) 184 51.7 8.1e-06 XP_005273669 (OMIM: 601872) PREDICTED: cationic am ( 658) 184 51.7 8.1e-06 XP_016869235 (OMIM: 601872) PREDICTED: cationic am ( 658) 184 51.7 8.1e-06 NP_003037 (OMIM: 601872) cationic amino acid trans ( 697) 184 51.7 8.4e-06 NP_001158243 (OMIM: 601872) cationic amino acid tr ( 698) 184 51.7 8.5e-06 NP_066000 (OMIM: 615720,615725) probable cationic ( 771) 177 50.1 2.8e-05 NP_001041629 (OMIM: 300443) cationic amino acid tr ( 619) 174 49.3 3.8e-05 >>XP_011521736 (OMIM: 605641) PREDICTED: Y+L amino acid (515 aa) initn: 3394 init1: 3394 opt: 3394 Z-score: 4218.1 bits: 790.1 E(85289): 0 Smith-Waterman score: 3394; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 430 440 450 460 470 480 490 500 510 pF1KSD RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::::::::::::::::::::::::::::::::::: XP_011 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 490 500 510 >>XP_011521735 (OMIM: 605641) PREDICTED: Y+L amino acid (515 aa) initn: 3394 init1: 3394 opt: 3394 Z-score: 4218.1 bits: 790.1 E(85289): 0 Smith-Waterman score: 3394; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 430 440 450 460 470 480 490 500 510 pF1KSD RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::::::::::::::::::::::::::::::::::: XP_011 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 490 500 510 >>NP_001070253 (OMIM: 605641) Y+L amino acid transporter (515 aa) initn: 3394 init1: 3394 opt: 3394 Z-score: 4218.1 bits: 790.1 E(85289): 0 Smith-Waterman score: 3394; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 430 440 450 460 470 480 490 500 510 pF1KSD RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::::::::::::::::::::::::::::::::::: NP_001 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 490 500 510 >>NP_003974 (OMIM: 605641) Y+L amino acid transporter 2 (515 aa) initn: 3394 init1: 3394 opt: 3394 Z-score: 4218.1 bits: 790.1 E(85289): 0 Smith-Waterman score: 3394; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 430 440 450 460 470 480 490 500 510 pF1KSD RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::::::::::::::::::::::::::::::::::: NP_003 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 490 500 510 >>XP_011521740 (OMIM: 605641) PREDICTED: Y+L amino acid (515 aa) initn: 3394 init1: 3394 opt: 3394 Z-score: 4218.1 bits: 790.1 E(85289): 0 Smith-Waterman score: 3394; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 430 440 450 460 470 480 490 500 510 pF1KSD RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::::::::::::::::::::::::::::::::::: XP_011 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 490 500 510 >>XP_006720365 (OMIM: 222700,603593) PREDICTED: Y+L amin (511 aa) initn: 2530 init1: 2503 opt: 2522 Z-score: 3133.9 bits: 589.5 E(85289): 8e-168 Smith-Waterman score: 2522; 73.6% identity (89.2% similar) in 500 aa overlap (20-515:11-507) 10 20 30 40 50 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVG :: .:: : .:: . : ..::::::::::: :.:: XP_006 MVDSTEYEVASQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVG 10 20 30 40 60 70 80 90 100 110 pF1KSD NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYIL :::::::::::::::...::.:.::..::.:::::: :::::::::::: :::::::::: XP_006 NMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD EAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICL ::::::.::::::.:::..:::.:::::::::::..:: :::: :: : :::::::::: XP_006 EAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD LTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNL :::.::::::::: ::: ::::::.::::.:: :.:.: :: : ::...:::::. .:.. XP_006 LTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD SLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIS .:::::::::::::::::.::::::::::::::.:::::::::.:::::::::::::.. XP_006 ALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD DVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLL :.:.::::::::::: ::.:.: ::..::::::::::::: :.::::::::::::::: . XP_006 DILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAI 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD SMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEP :::.:::::.:.:::: :::::: :::.::::::.:::::::::::.::::::::::: XP_006 CMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEP 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRR ::::::::::::::::.:..::: :::..:::::::::.:::::.::::. . .:: .: XP_006 DRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKR 410 420 430 440 450 460 480 490 500 510 pF1KSD PLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::..: .... :: : ::. : .:.:. . . .. : XP_006 PLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 470 480 490 500 510 >>NP_001119577 (OMIM: 222700,603593) Y+L amino acid tran (511 aa) initn: 2530 init1: 2503 opt: 2522 Z-score: 3133.9 bits: 589.5 E(85289): 8e-168 Smith-Waterman score: 2522; 73.6% identity (89.2% similar) in 500 aa overlap (20-515:11-507) 10 20 30 40 50 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVG :: .:: : .:: . : ..::::::::::: :.:: NP_001 MVDSTEYEVASQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVG 10 20 30 40 60 70 80 90 100 110 pF1KSD NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYIL :::::::::::::::...::.:.::..::.:::::: :::::::::::: :::::::::: NP_001 NMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD EAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICL ::::::.::::::.:::..:::.:::::::::::..:: :::: :: : :::::::::: NP_001 EAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD LTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNL :::.::::::::: ::: ::::::.::::.:: :.:.: :: : ::...:::::. .:.. NP_001 LTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD SLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIS .:::::::::::::::::.::::::::::::::.:::::::::.:::::::::::::.. NP_001 ALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD DVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLL :.:.::::::::::: ::.:.: ::..::::::::::::: :.::::::::::::::: . NP_001 DILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAI 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD SMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEP :::.:::::.:.:::: :::::: :::.::::::.:::::::::::.::::::::::: NP_001 CMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEP 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRR ::::::::::::::::.:..::: :::..:::::::::.:::::.::::. . .:: .: NP_001 DRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKR 410 420 430 440 450 460 480 490 500 510 pF1KSD PLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::..: .... :: : ::. : .:.:. . . .. : NP_001 PLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 470 480 490 500 510 >>XP_011535600 (OMIM: 222700,603593) PREDICTED: Y+L amin (511 aa) initn: 2530 init1: 2503 opt: 2522 Z-score: 3133.9 bits: 589.5 E(85289): 8e-168 Smith-Waterman score: 2522; 73.6% identity (89.2% similar) in 500 aa overlap (20-515:11-507) 10 20 30 40 50 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVG :: .:: : .:: . : ..::::::::::: :.:: XP_011 MVDSTEYEVASQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVG 10 20 30 40 60 70 80 90 100 110 pF1KSD NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYIL :::::::::::::::...::.:.::..::.:::::: :::::::::::: :::::::::: XP_011 NMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD EAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICL ::::::.::::::.:::..:::.:::::::::::..:: :::: :: : :::::::::: XP_011 EAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD LTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNL :::.::::::::: ::: ::::::.::::.:: :.:.: :: : ::...:::::. .:.. XP_011 LTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD SLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIS .:::::::::::::::::.::::::::::::::.:::::::::.:::::::::::::.. XP_011 ALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD DVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLL :.:.::::::::::: ::.:.: ::..::::::::::::: :.::::::::::::::: . XP_011 DILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAI 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD SMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEP :::.:::::.:.:::: :::::: :::.::::::.:::::::::::.::::::::::: XP_011 CMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEP 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRR ::::::::::::::::.:..::: :::..:::::::::.:::::.::::. . .:: .: XP_011 DRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKR 410 420 430 440 450 460 480 490 500 510 pF1KSD PLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::..: .... :: : ::. : .:.:. . . .. : XP_011 PLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 470 480 490 500 510 >>NP_001119578 (OMIM: 222700,603593) Y+L amino acid tran (511 aa) initn: 2530 init1: 2503 opt: 2522 Z-score: 3133.9 bits: 589.5 E(85289): 8e-168 Smith-Waterman score: 2522; 73.6% identity (89.2% similar) in 500 aa overlap (20-515:11-507) 10 20 30 40 50 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVG :: .:: : .:: . : ..::::::::::: :.:: NP_001 MVDSTEYEVASQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVG 10 20 30 40 60 70 80 90 100 110 pF1KSD NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYIL :::::::::::::::...::.:.::..::.:::::: :::::::::::: :::::::::: NP_001 NMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD EAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICL ::::::.::::::.:::..:::.:::::::::::..:: :::: :: : :::::::::: NP_001 EAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD LTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNL :::.::::::::: ::: ::::::.::::.:: :.:.: :: : ::...:::::. .:.. NP_001 LTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD SLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIS .:::::::::::::::::.::::::::::::::.:::::::::.:::::::::::::.. NP_001 ALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD DVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLL :.:.::::::::::: ::.:.: ::..::::::::::::: :.::::::::::::::: . NP_001 DILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAI 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD SMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEP :::.:::::.:.:::: :::::: :::.::::::.:::::::::::.::::::::::: NP_001 CMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEP 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRR ::::::::::::::::.:..::: :::..:::::::::.:::::.::::. . .:: .: NP_001 DRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKR 410 420 430 440 450 460 480 490 500 510 pF1KSD PLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::..: .... :: : ::. : .:.:. . . .. : NP_001 PLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 470 480 490 500 510 >>XP_011535601 (OMIM: 222700,603593) PREDICTED: Y+L amin (511 aa) initn: 2530 init1: 2503 opt: 2522 Z-score: 3133.9 bits: 589.5 E(85289): 8e-168 Smith-Waterman score: 2522; 73.6% identity (89.2% similar) in 500 aa overlap (20-515:11-507) 10 20 30 40 50 pF1KSD MEAREPGRPTPTYHLVPNTSQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVG :: .:: : .:: . : ..::::::::::: :.:: XP_011 MVDSTEYEVASQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVG 10 20 30 40 60 70 80 90 100 110 pF1KSD NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYIL :::::::::::::::...::.:.::..::.:::::: :::::::::::: :::::::::: XP_011 NMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD EAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICL ::::::.::::::.:::..:::.:::::::::::..:: :::: :: : :::::::::: XP_011 EAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD LTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNL :::.::::::::: ::: ::::::.::::.:: :.:.: :: : ::...:::::. .:.. XP_011 LTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD SLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIS .:::::::::::::::::.::::::::::::::.:::::::::.:::::::::::::.. XP_011 ALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD DVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLL :.:.::::::::::: ::.:.: ::..::::::::::::: :.::::::::::::::: . XP_011 DILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAI 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD SMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEP :::.:::::.:.:::: :::::: :::.::::::.:::::::::::.::::::::::: XP_011 CMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEP 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRR ::::::::::::::::.:..::: :::..:::::::::.:::::.::::. . .:: .: XP_011 DRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKR 410 420 430 440 450 460 480 490 500 510 pF1KSD PLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD ::..: .... :: : ::. : .:.:. . . .. : XP_011 PLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN 470 480 490 500 510 515 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:53:28 2016 done: Thu Nov 3 00:53:29 2016 Total Scan time: 7.840 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]