FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0248, 1859 aa 1>>>pF1KSDA0248 1859 - 1859 aa - 1859 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.4637+/-0.000516; mu= -9.1886+/- 0.032 mean_var=381.2525+/-80.269, 0's: 0 Z-trim(118.5): 106 B-trim: 296 in 1/54 Lambda= 0.065685 statistics sampled from 31502 (31608) to 31502 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.371), width: 16 Scan time: 16.200 The best scores are: opt bits E(85289) NP_004184 (OMIM: 603698) Golgi-specific brefeldin (1859) 12326 1184.0 0 XP_005270318 (OMIM: 603698) PREDICTED: Golgi-speci (1860) 12314 1182.9 0 NP_001186308 (OMIM: 603698) Golgi-specific brefeld (1855) 12283 1179.9 0 NP_001186307 (OMIM: 603698) Golgi-specific brefeld (1856) 12271 1178.8 0 XP_006718111 (OMIM: 603698) PREDICTED: Golgi-speci (1892) 10961 1054.7 0 XP_016872350 (OMIM: 603698) PREDICTED: Golgi-speci (1885) 10950 1053.6 0 XP_006718110 (OMIM: 603698) PREDICTED: Golgi-speci (1893) 10949 1053.5 0 XP_006718112 (OMIM: 603698) PREDICTED: Golgi-speci (1889) 10906 1049.5 0 XP_011538616 (OMIM: 603698) PREDICTED: Golgi-speci (1416) 9299 897.1 0 XP_011538615 (OMIM: 603698) PREDICTED: Golgi-speci (1638) 9159 883.9 0 XP_016872352 (OMIM: 603698) PREDICTED: Golgi-speci (1847) 8258 798.5 0 XP_006718113 (OMIM: 603698) PREDICTED: Golgi-speci (1881) 8258 798.5 0 XP_016872351 (OMIM: 603698) PREDICTED: Golgi-speci (1877) 8215 794.5 0 XP_011538614 (OMIM: 603698) PREDICTED: Golgi-speci (1846) 7937 768.1 0 XP_016872353 (OMIM: 603698) PREDICTED: Golgi-speci (1028) 6870 666.8 3e-190 NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens ( 399) 508 63.7 4.2e-09 XP_011523778 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 497 62.6 7.3e-09 XP_011523777 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 497 62.6 7.3e-09 XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 ( 338) 497 62.6 7.6e-09 NP_001278948 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 497 62.6 7.6e-09 NP_001278947 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 497 62.6 7.6e-09 XP_011523779 (OMIM: 182115) PREDICTED: cytohesin-1 ( 339) 497 62.6 7.6e-09 XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 ( 380) 498 62.7 7.8e-09 NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Ho ( 397) 498 62.8 8.1e-09 NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Ho ( 398) 498 62.8 8.1e-09 XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 ( 399) 498 62.8 8.1e-09 XP_011515744 (OMIM: 604141) PREDICTED: brefeldin A (1649) 505 63.8 1.6e-08 XP_005260309 (OMIM: 605371,608097) PREDICTED: bref (1784) 505 63.8 1.7e-08 NP_006411 (OMIM: 605371,608097) brefeldin A-inhibi (1785) 505 63.8 1.8e-08 XP_005251193 (OMIM: 604141) PREDICTED: brefeldin A (1800) 505 63.8 1.8e-08 XP_005251192 (OMIM: 604141) PREDICTED: brefeldin A (1843) 505 63.8 1.8e-08 XP_005251191 (OMIM: 604141) PREDICTED: brefeldin A (1849) 505 63.8 1.8e-08 NP_006412 (OMIM: 604141) brefeldin A-inhibited gua (1849) 505 63.8 1.8e-08 NP_037517 (OMIM: 606514) cytohesin-4 isoform 1 [Ho ( 394) 484 61.4 2e-08 XP_006723536 (OMIM: 602488) PREDICTED: cytohesin-2 ( 394) 482 61.2 2.3e-08 NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Ho ( 399) 482 61.2 2.3e-08 NP_059431 (OMIM: 602488) cytohesin-2 isoform 1 [Ho ( 400) 482 61.2 2.3e-08 XP_006723535 (OMIM: 602488) PREDICTED: cytohesin-2 ( 421) 482 61.3 2.4e-08 XP_011528449 (OMIM: 606514) PREDICTED: cytohesin-4 ( 337) 474 60.4 3.4e-08 NP_001304953 (OMIM: 606514) cytohesin-4 isoform 2 ( 337) 474 60.4 3.4e-08 NP_056047 (OMIM: 612118) IQ motif and SEC7 domain- ( 759) 467 60.0 1.1e-07 XP_011519263 (OMIM: 612118) PREDICTED: IQ motif an ( 879) 467 60.0 1.2e-07 XP_016874800 (OMIM: 612118) PREDICTED: IQ motif an (1041) 467 60.1 1.4e-07 XP_016874799 (OMIM: 612118) PREDICTED: IQ motif an (1041) 467 60.1 1.4e-07 XP_011519262 (OMIM: 612118) PREDICTED: IQ motif an (1062) 467 60.1 1.4e-07 XP_011519261 (OMIM: 612118) PREDICTED: IQ motif an (1062) 467 60.1 1.4e-07 XP_011519260 (OMIM: 612118) PREDICTED: IQ motif an (1063) 467 60.1 1.4e-07 NP_001164209 (OMIM: 612118) IQ motif and SEC7 doma (1182) 467 60.1 1.5e-07 XP_011532617 (OMIM: 610166) PREDICTED: IQ motif an ( 814) 459 59.2 1.9e-07 NP_001317548 (OMIM: 610166) IQ motif and SEC7 doma ( 814) 459 59.2 1.9e-07 >>NP_004184 (OMIM: 603698) Golgi-specific brefeldin A-re (1859 aa) initn: 12326 init1: 12326 opt: 12326 Z-score: 6327.1 bits: 1184.0 E(85289): 0 Smith-Waterman score: 12326; 99.9% identity (100.0% similar) in 1859 aa overlap (1-1859:1-1859) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_004 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KSD PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1810 1820 1830 1840 1850 >>XP_005270318 (OMIM: 603698) PREDICTED: Golgi-specific (1860 aa) initn: 10147 init1: 10147 opt: 12314 Z-score: 6321.0 bits: 1182.9 E(85289): 0 Smith-Waterman score: 12314; 99.9% identity (99.9% similar) in 1860 aa overlap (1-1859:1-1860) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_005 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 250 260 270 280 290 300 310 320 330 340 350 pF1KSD TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQ-EGTHVEKSQSASVESIPEVLEE ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_005 TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQQEGTHVEKSQSASVESIPEVLEE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD CTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD RHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD INYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD LTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQ 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD FLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLD 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYV 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD WNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFR 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD KCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSF 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD VSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALV 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD SVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KSD VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHS 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KSD GDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSD 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KSD SEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKS 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KSD HKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KSD DLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KSD VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRA 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KSD STLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMD 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KSD TAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KSD HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KSD PPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1810 1820 1830 1840 1850 1860 >>NP_001186308 (OMIM: 603698) Golgi-specific brefeldin A (1855 aa) initn: 9896 init1: 9834 opt: 12283 Z-score: 6305.1 bits: 1179.9 E(85289): 0 Smith-Waterman score: 12283; 99.7% identity (99.8% similar) in 1859 aa overlap (1-1859:1-1855) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_001 KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQ----LLD 1450 1460 1470 1480 1490 1510 1520 1530 1540 1550 1560 pF1KSD LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV 1500 1510 1520 1530 1540 1550 1570 1580 1590 1600 1610 1620 pF1KSD RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS 1560 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KSD TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KSD AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 1790 1800 pF1KSD LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP 1740 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 pF1KSD PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1800 1810 1820 1830 1840 1850 >>NP_001186307 (OMIM: 603698) Golgi-specific brefeldin A (1856 aa) initn: 7717 init1: 7655 opt: 12271 Z-score: 6298.9 bits: 1178.8 E(85289): 0 Smith-Waterman score: 12271; 99.7% identity (99.7% similar) in 1860 aa overlap (1-1859:1-1856) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 250 260 270 280 290 300 310 320 330 340 350 pF1KSD TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQ-EGTHVEKSQSASVESIPEVLEE ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQQEGTHVEKSQSASVESIPEVLEE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD CTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD RHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELY 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD INYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD LTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQ 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD FLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLD 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYV 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD WNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFR 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD KCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSF 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD VSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALV 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD SVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KSD VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHS 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KSD GDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSD 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KSD SEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKS 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KSD HKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::: :: NP_001 HKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQ----LL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 pF1KSD DLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KSD VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRA 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 pF1KSD STLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMD 1620 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 pF1KSD TAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA 1680 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KSD HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG 1740 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KSD PPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1800 1810 1820 1830 1840 1850 >>XP_006718111 (OMIM: 603698) PREDICTED: Golgi-specific (1892 aa) initn: 10961 init1: 10961 opt: 10961 Z-score: 5627.9 bits: 1054.7 E(85289): 0 Smith-Waterman score: 12243; 98.2% identity (98.3% similar) in 1891 aa overlap (2-1859:2-1892) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_006 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKK--------------------------- ::::::::::::::::::::::::::::::::: XP_006 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKISPCLLNKLELSSGEQTKALNQLERVL 190 200 210 220 230 240 220 230 240 250 260 pF1KSD ------LKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKNLKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD LGVPEQPDLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGVPEQPDLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KSD SSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQ 430 440 450 460 470 480 450 460 470 480 490 500 pF1KSD TLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIIT 490 500 510 520 530 540 510 520 530 540 550 560 pF1KSD VENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVS 550 560 570 580 590 600 570 580 590 600 610 620 pF1KSD GQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTER 610 620 630 640 650 660 630 640 650 660 670 680 pF1KSD TASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLL 670 680 690 700 710 720 690 700 710 720 730 740 pF1KSD PDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLD 730 740 750 760 770 780 750 760 770 780 790 800 pF1KSD KKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTE 790 800 810 820 830 840 810 820 830 840 850 860 pF1KSD RWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDF 850 860 870 880 890 900 870 880 890 900 910 920 pF1KSD EQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLF 910 920 930 940 950 960 930 940 950 960 970 980 pF1KSD TMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTAL 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KSD SSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAM 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD IEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVA 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD LECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLEN 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD RDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRIL 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD LLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATA 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD RADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWL 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD VVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHIT 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD PDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQ 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KSD HASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGG 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 1580 pF1KSD QKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWES 1570 1580 1590 1600 1610 1620 1590 1600 1610 1620 1630 1640 pF1KSD CFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTI 1630 1640 1650 1660 1670 1680 1650 1660 1670 1680 1690 1700 pF1KSD LDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDC 1690 1700 1710 1720 1730 1740 1710 1720 1730 1740 1750 1760 pF1KSD FLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACD 1750 1760 1770 1780 1790 1800 1770 1780 1790 1800 1810 1820 pF1KSD FEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLP 1810 1820 1830 1840 1850 1860 1830 1840 1850 pF1KSD IILNPALIEATSPVPLLATPRPTDPIPTSEVN :::::::::::::::::::::::::::::::: XP_006 IILNPALIEATSPVPLLATPRPTDPIPTSEVN 1870 1880 1890 >>XP_016872350 (OMIM: 603698) PREDICTED: Golgi-specific (1885 aa) initn: 11506 init1: 10147 opt: 10950 Z-score: 5622.3 bits: 1053.6 E(85289): 0 Smith-Waterman score: 12254; 98.6% identity (98.6% similar) in 1885 aa overlap (1-1859:1-1885) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_016 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKK-------------------------LK ::::::::::::::::::::::::::::::::: :: XP_016 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKISPCLLNKLELSSGEQTKALNQLERLK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD MRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPIS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD SASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPD 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD LQ-EGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGT :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD ALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIK 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD DEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIITVENPKMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIITVENPKMP 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD YEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTH 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD LLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKA 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD VGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELI 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD EIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEF 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD VSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNG 790 800 810 820 830 840 820 830 840 850 860 870 pF1KSD SPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILED 850 860 870 880 890 900 880 890 900 910 920 930 pF1KSD MYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD IAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIEN 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD LPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFV 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD DPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQC 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD DPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCV 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD WQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSV 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD LSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDA 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KSD GAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDV 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KSD DNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELC 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD VKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQ 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD SDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADS 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KSD RTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLF 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KSD PLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKY 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KSD MHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRD 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KSD ELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESP 1750 1760 1770 1780 1790 1800 1780 1790 1800 1810 1820 1830 pF1KSD RAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPAL 1810 1820 1830 1840 1850 1860 1840 1850 pF1KSD IEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::: XP_016 IEATSPVPLLATPRPTDPIPTSEVN 1870 1880 >>XP_006718110 (OMIM: 603698) PREDICTED: Golgi-specific (1893 aa) initn: 11506 init1: 10147 opt: 10949 Z-score: 5621.8 bits: 1053.5 E(85289): 0 Smith-Waterman score: 12226; 98.1% identity (98.2% similar) in 1891 aa overlap (3-1859:3-1893) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_006 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKK--------------------------- ::::::::::::::::::::::::::::::::: XP_006 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKISPCLLNKLELSSGEQTKALNQLERVL 190 200 210 220 230 240 220 230 240 250 260 pF1KSD ------LKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKNLKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD LGVPEQPDLQ-EGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGVPEQPDLQQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT 370 380 390 400 410 420 390 400 410 420 430 440 pF1KSD QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC 430 440 450 460 470 480 450 460 470 480 490 500 pF1KSD QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII 490 500 510 520 530 540 510 520 530 540 550 560 pF1KSD TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV 550 560 570 580 590 600 570 580 590 600 610 620 pF1KSD SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KSD RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL 670 680 690 700 710 720 690 700 710 720 730 740 pF1KSD LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL 730 740 750 760 770 780 750 760 770 780 790 800 pF1KSD DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT 790 800 810 820 830 840 810 820 830 840 850 860 pF1KSD ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD 850 860 870 880 890 900 870 880 890 900 910 920 pF1KSD FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL 910 920 930 940 950 960 930 940 950 960 970 980 pF1KSD FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KSD LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KSD QHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETG 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 1580 pF1KSD GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE 1570 1580 1590 1600 1610 1620 1590 1600 1610 1620 1630 1640 pF1KSD SCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLT 1630 1640 1650 1660 1670 1680 1650 1660 1670 1680 1690 1700 pF1KSD ILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERID 1690 1700 1710 1720 1730 1740 1710 1720 1730 1740 1750 1760 pF1KSD CFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGAC 1750 1760 1770 1780 1790 1800 1770 1780 1790 1800 1810 1820 pF1KSD DFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTL 1810 1820 1830 1840 1850 1860 1830 1840 1850 pF1KSD PIILNPALIEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::::::::::: XP_006 PIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1870 1880 1890 >>XP_006718112 (OMIM: 603698) PREDICTED: Golgi-specific (1889 aa) initn: 9076 init1: 7655 opt: 10906 Z-score: 5599.8 bits: 1049.5 E(85289): 0 Smith-Waterman score: 12183; 97.9% identity (98.0% similar) in 1891 aa overlap (3-1859:3-1889) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_006 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKK--------------------------- ::::::::::::::::::::::::::::::::: XP_006 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKISPCLLNKLELSSGEQTKALNQLERVL 190 200 210 220 230 240 220 230 240 250 260 pF1KSD ------LKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFKNLKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD LGVPEQPDLQ-EGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGVPEQPDLQQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT 370 380 390 400 410 420 390 400 410 420 430 440 pF1KSD QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC 430 440 450 460 470 480 450 460 470 480 490 500 pF1KSD QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII 490 500 510 520 530 540 510 520 530 540 550 560 pF1KSD TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV 550 560 570 580 590 600 570 580 590 600 610 620 pF1KSD SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KSD RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL 670 680 690 700 710 720 690 700 710 720 730 740 pF1KSD LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL 730 740 750 760 770 780 750 760 770 780 790 800 pF1KSD DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT 790 800 810 820 830 840 810 820 830 840 850 860 pF1KSD ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD 850 860 870 880 890 900 870 880 890 900 910 920 pF1KSD FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL 910 920 930 940 950 960 930 940 950 960 970 980 pF1KSD FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KSD LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KSD QHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETG ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_006 QHASRGGQSDDDEDEGVPASYHTVSLQ----LLDLMHTLHTRAASIYSSWAEEQRHLETG 1510 1520 1530 1540 1550 1530 1540 1550 1560 1570 1580 pF1KSD GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE 1560 1570 1580 1590 1600 1610 1590 1600 1610 1620 1630 1640 pF1KSD SCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLT 1620 1630 1640 1650 1660 1670 1650 1660 1670 1680 1690 1700 pF1KSD ILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERID 1680 1690 1700 1710 1720 1730 1710 1720 1730 1740 1750 1760 pF1KSD CFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGAC 1740 1750 1760 1770 1780 1790 1770 1780 1790 1800 1810 1820 pF1KSD DFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTL 1800 1810 1820 1830 1840 1850 1830 1840 1850 pF1KSD PIILNPALIEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::::::::::: XP_006 PIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1860 1870 1880 >>XP_011538616 (OMIM: 603698) PREDICTED: Golgi-specific (1416 aa) initn: 9299 init1: 9299 opt: 9299 Z-score: 4778.6 bits: 897.1 E(85289): 0 Smith-Waterman score: 9299; 99.9% identity (100.0% similar) in 1397 aa overlap (463-1859:20-1416) 440 450 460 470 480 490 pF1KSD LLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLK .::::::::::::::::::::::::::::: XP_011 MTWITSIPGACALHSPPRKKLLSIERLNLYAASLRVCFLLFESMREHLK 10 20 30 40 500 510 520 530 540 550 pF1KSD FQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLF 50 60 70 80 90 100 560 570 580 590 600 610 pF1KSD EELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPS 110 120 130 140 150 160 620 630 640 650 660 670 pF1KSD CEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGA 170 180 190 200 210 220 680 690 700 710 720 730 pF1KSD DKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMD 230 240 250 260 270 280 740 750 760 770 780 790 pF1KSD NTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLP 290 300 310 320 330 340 800 810 820 830 840 850 pF1KSD GEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLE 350 360 370 380 390 400 860 870 880 890 900 910 pF1KSD EFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEG 410 420 430 440 450 460 920 930 940 950 960 970 pF1KSD IFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSD 470 480 490 500 510 520 980 990 1000 1010 1020 1030 pF1KSD VFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIME 530 540 550 560 570 580 1040 1050 1060 1070 1080 1090 pF1KSD AMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSS 590 600 610 620 630 640 1100 1110 1120 1130 1140 1150 pF1KSD VRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEED 650 660 670 680 690 700 1160 1170 1180 1190 1200 1210 pF1KSD AAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLR 710 720 730 740 750 760 1220 1230 1240 1250 1260 1270 pF1KSD REEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLEC 770 780 790 800 810 820 1280 1290 1300 1310 1320 1330 pF1KSD IGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKI 830 840 850 860 870 880 1340 1350 1360 1370 1380 1390 pF1KSD HRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKC 890 900 910 920 930 940 1400 1410 1420 1430 1440 1450 pF1KSD VESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKK 950 960 970 980 990 1000 1460 1470 1480 1490 1500 1510 pF1KSD SKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASI 1010 1020 1030 1040 1050 1060 1520 1530 1540 1550 1560 1570 pF1KSD YSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRAL 1070 1080 1090 1100 1110 1120 1580 1590 1600 1610 1620 1630 pF1KSD LVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLS 1130 1140 1150 1160 1170 1180 1640 1650 1660 1670 1680 1690 pF1KSD PLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGG 1190 1200 1210 1220 1230 1240 1700 1710 1720 1730 1740 1750 pF1KSD GPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPG 1250 1260 1270 1280 1290 1300 1760 1770 1780 1790 1800 1810 pF1KSD HPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQP 1310 1320 1330 1340 1350 1360 1820 1830 1840 1850 pF1KSD LASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1370 1380 1390 1400 1410 >>XP_011538615 (OMIM: 603698) PREDICTED: Golgi-specific (1638 aa) initn: 9714 init1: 8355 opt: 9159 Z-score: 4705.9 bits: 883.9 E(85289): 0 Smith-Waterman score: 10436; 97.5% identity (97.7% similar) in 1632 aa overlap (3-1600:3-1634) 10 20 30 40 50 60 pF1KSD MVDKNIYIIQGEINIVVGAIKRNSRWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 130 140 150 160 170 180 190 200 210 pF1KSD AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKK--------------------------- ::::::::::::::::::::::::::::::::: XP_011 AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKISPCLLNKLELSSGEQTKALNQLERVL 190 200 210 220 230 240 220 230 240 250 260 pF1KSD ------LKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFKNLKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDVPTPISSASSEAASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD LGVPEQPDLQ-EGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGVPEQPDLQQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFT 370 380 390 400 410 420 390 400 410 420 430 440 pF1KSD QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQC 430 440 450 460 470 480 450 460 470 480 490 500 pF1KSD QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEII 490 500 510 520 530 540 510 520 530 540 550 560 pF1KSD TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPV 550 560 570 580 590 600 570 580 590 600 610 620 pF1KSD SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KSD RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCL 670 680 690 700 710 720 690 700 710 720 730 740 pF1KSD LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRL 730 740 750 760 770 780 750 760 770 780 790 800 pF1KSD DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFT 790 800 810 820 830 840 810 820 830 840 850 860 pF1KSD ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKD 850 860 870 880 890 900 870 880 890 900 910 920 pF1KSD FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDL 910 920 930 940 950 960 930 940 950 960 970 980 pF1KSD FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTA 970 980 990 1000 1010 1020 990 1000 1010 1020 1030 1040 pF1KSD LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKA 1030 1040 1050 1060 1070 1080 1050 1060 1070 1080 1090 1100 pF1KSD MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRV 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLE 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISAQVLLSLRI 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQAT 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGW 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHI 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSS 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KSD QHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETG 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 1580 pF1KSD GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWE 1570 1580 1590 1600 1610 1620 1590 1600 1610 1620 1630 1640 pF1KSD SCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLT :::::: .: :. XP_011 SCFNKVGLPTGLKIKFKS 1630 1859 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:54:20 2016 done: Thu Nov 3 00:54:22 2016 Total Scan time: 16.200 Total Display time: 1.210 Function used was FASTA [36.3.4 Apr, 2011]