FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0250, 1091 aa 1>>>pF1KSDA0250 1091 - 1091 aa - 1091 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.3056+/-0.00132; mu= -14.7383+/- 0.079 mean_var=417.2243+/-87.223, 0's: 0 Z-trim(112.7): 40 B-trim: 374 in 1/50 Lambda= 0.062790 statistics sampled from 13415 (13440) to 13415 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.413), width: 16 Scan time: 4.690 The best scores are: opt bits E(32554) CCDS53444.1 SMG7 gene_id:9887|Hs108|chr1 (1091) 7384 684.1 4.5e-196 CCDS41445.2 SMG7 gene_id:9887|Hs108|chr1 (1178) 5879 547.8 5.3e-155 CCDS81410.1 SMG7 gene_id:9887|Hs108|chr1 (1170) 5828 543.2 1.3e-153 CCDS1355.1 SMG7 gene_id:9887|Hs108|chr1 (1137) 3785 358.1 6.5e-98 CCDS53445.1 SMG7 gene_id:9887|Hs108|chr1 (1145) 3520 334.1 1.1e-90 >>CCDS53444.1 SMG7 gene_id:9887|Hs108|chr1 (1091 aa) initn: 7384 init1: 7384 opt: 7384 Z-score: 3633.5 bits: 684.1 E(32554): 4.5e-196 Smith-Waterman score: 7384; 99.9% identity (100.0% similar) in 1091 aa overlap (1-1091:1-1091) 10 20 30 40 50 60 pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QANIDRRGKRSPGIFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ 1030 1040 1050 1060 1070 1080 1090 pF1KSD QRGQGTMNPPH ::::::::::: CCDS53 QRGQGTMNPPH 1090 >>CCDS41445.2 SMG7 gene_id:9887|Hs108|chr1 (1178 aa) initn: 7107 init1: 5867 opt: 5879 Z-score: 2896.2 bits: 547.8 E(32554): 5.3e-155 Smith-Waterman score: 7013; 94.5% identity (95.2% similar) in 1116 aa overlap (1-1066:1-1115) 10 20 30 40 50 60 pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ 790 800 810 820 830 840 850 860 pF1KSD QANIDRRGKRSPGIFRPEQDPVPRMPFE-------------------------------- :::::::::::::.:::::::::::::: CCDS41 QANIDRRGKRSPGVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPD 850 860 870 880 890 900 870 880 890 900 910 pF1KSD ------------------KSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK :::::::::::::::::::::::::::::::::::::::::: CCDS41 LYPALLGPLASLPGRSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK 910 920 930 940 950 960 920 930 940 950 960 970 pF1KSD NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KSD PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KSD PSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP ::::::::::::::::::::::::. . .... :: CCDS41 PSGTWTGHGPSMEDSSAVLMESLKK-QQHGVQQLGPKRQSEEEGSSSICVAHRGPRPLPS 1090 1100 1110 1120 1130 pF1KSD H CCDS41 CSLPASTFRVKFKAARTCAHQAQKKTRRRPFWKRRKKGK 1140 1150 1160 1170 >>CCDS81410.1 SMG7 gene_id:9887|Hs108|chr1 (1170 aa) initn: 7318 init1: 5815 opt: 5828 Z-score: 2871.3 bits: 543.2 E(32554): 1.3e-153 Smith-Waterman score: 7090; 95.0% identity (95.5% similar) in 1121 aa overlap (3-1073:33-1152) 10 20 30 pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS :.:.. .::::::::::::::::::::::: CCDS81 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN 790 800 810 820 830 840 820 830 840 850 860 pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFE---- :::::::::::::::::::::::::::::::::::::::::.:::::::::::::: CCDS81 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEDPKS 850 860 870 880 890 900 870 880 pF1KSD ----------------------------------------------KSLLEKPSELMSHS :::::::::::::: CCDS81 SPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHS 910 920 930 940 950 960 890 900 910 920 930 940 pF1KSD SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 970 980 990 1000 1010 1020 950 960 970 980 990 1000 pF1KSD SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 1030 1040 1050 1060 1070 1080 1010 1020 1030 1040 1050 1060 pF1KSD DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1090 1100 1110 1120 1130 1140 1070 1080 1090 pF1KSD HPGPSALEQLLMQQKQKQQRGQGTMNPPH ::::::::::: CCDS81 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1150 1160 1170 >>CCDS1355.1 SMG7 gene_id:9887|Hs108|chr1 (1137 aa) initn: 3854 init1: 3762 opt: 3785 Z-score: 1871.3 bits: 358.1 E(32554): 6.5e-98 Smith-Waterman score: 7176; 95.8% identity (95.9% similar) in 1123 aa overlap (1-1077:1-1123) 10 20 30 40 50 60 pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 490 500 510 520 530 540 550 560 pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEV------------------------------- ::::::::::::::::::::::::::::: CCDS13 EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 550 560 570 580 590 600 570 580 590 600 610 pF1KSD ---------------KSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS ::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 610 620 630 640 650 660 620 630 640 650 660 670 pF1KSD RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 670 680 690 700 710 720 680 690 700 710 720 730 pF1KSD QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 730 740 750 760 770 780 740 750 760 770 780 790 pF1KSD SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 790 800 810 820 830 840 800 810 820 830 840 850 pF1KSD QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS13 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 850 860 870 880 890 900 860 870 880 890 900 910 pF1KSD FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 910 920 930 940 950 960 920 930 940 950 960 970 pF1KSD SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KSD HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KSD WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH ::::::::::::::::::::::::::::::::::::::::::: CCDS13 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1090 1100 1110 1120 1130 >>CCDS53445.1 SMG7 gene_id:9887|Hs108|chr1 (1145 aa) initn: 5084 init1: 3494 opt: 3520 Z-score: 1741.5 bits: 334.1 E(32554): 1.1e-90 Smith-Waterman score: 6462; 91.0% identity (91.1% similar) in 1081 aa overlap (43-1027:1-1081) 20 30 40 50 60 70 pF1KSD EVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTL :::::::::::::::::::::::::::::: CCDS53 MLVTDLEYALDKKVEQDLWNHAFKNQITTL 10 20 30 80 90 100 110 120 130 pF1KSD QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KSD AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KSD FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS 220 230 240 250 260 270 320 330 340 350 360 370 pF1KSD NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR 280 290 300 310 320 330 380 390 400 410 420 430 pF1KSD LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR 340 350 360 370 380 390 440 450 460 470 480 490 pF1KSD NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL 400 410 420 430 440 450 500 510 520 530 540 550 pF1KSD ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK 460 470 480 490 500 510 560 pF1KSD TREVNRDQGRSFPPKEV------------------------------------------- ::::::::::::::::: CCDS53 TREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVA 520 530 540 550 560 570 570 580 590 600 610 620 pF1KSD ---KSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIP 580 590 600 610 620 630 630 640 650 660 670 680 pF1KSD PPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQG 640 650 660 670 680 690 690 700 710 720 730 740 pF1KSD PQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQ 700 710 720 730 740 750 750 760 770 780 790 800 pF1KSD QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPF 760 770 780 790 800 810 810 820 830 840 850 860 pF1KSD PMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMP :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: CCDS53 PMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMP 820 830 840 850 860 870 870 pF1KSD FE--------------------------------------------------KSLLEKPS :: :::::::: CCDS53 FEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPS 880 890 900 910 920 930 880 890 900 910 920 930 pF1KSD ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFE 940 950 960 970 980 990 940 950 960 970 980 990 pF1KSD GTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRT 1000 1010 1020 1030 1040 1050 1000 1010 1020 1030 1040 1050 pF1KSD ADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSI ::::::::::::::::::::::::::::::: CCDS53 ADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSI 1060 1070 1080 1090 1100 1110 1060 1070 1080 1090 pF1KSD WSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH CCDS53 WSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1120 1130 1140 1091 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:55:13 2016 done: Thu Nov 3 00:55:14 2016 Total Scan time: 4.690 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]