Result of FASTA (omim) for
pF1KSDA0250
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0250, 1091 aa
1>>>pF1KSDA0250 1091 - 1091 aa - 1091 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.8383+/-0.000525; mu= -23.4671+/- 0.032
mean_var=526.9921+/-111.671, 0's: 0 Z-trim(120.7): 46 B-trim: 722 in 1/54
Lambda= 0.055869
statistics sampled from 36190 (36241) to 36190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.425), width: 16
Scan time: 14.910
The best scores are: opt bits E(85289)
NP_963862 (OMIM: 610964) protein SMG7 isoform 2 [H (1091) 7384 610.9 1.2e-173
XP_011508511 (OMIM: 610964) PREDICTED: protein SMG (1120) 7333 606.8 2.2e-172
XP_016858456 (OMIM: 610964) PREDICTED: protein SMG (1120) 7333 606.8 2.2e-172
XP_016858457 (OMIM: 610964) PREDICTED: protein SMG (1049) 7116 589.3 3.8e-167
XP_006711741 (OMIM: 610964) PREDICTED: protein SMG (1141) 5879 489.6 4.2e-137
NP_963863 (OMIM: 610964) protein SMG7 isoform 4 [H (1178) 5879 489.7 4.4e-137
XP_016858455 (OMIM: 610964) PREDICTED: protein SMG (1170) 5828 485.5 7.5e-136
XP_011508508 (OMIM: 610964) PREDICTED: protein SMG (1170) 5828 485.5 7.5e-136
NP_001317936 (OMIM: 610964) protein SMG7 isoform 6 (1170) 5828 485.5 7.5e-136
XP_011508512 (OMIM: 610964) PREDICTED: protein SMG (1099) 5611 468.0 1.3e-130
XP_005245709 (OMIM: 610964) PREDICTED: protein SMG (1187) 3788 321.1 2.4e-86
NP_775179 (OMIM: 610964) protein SMG7 isoform 1 [H (1137) 3785 320.9 2.7e-86
XP_005245706 (OMIM: 610964) PREDICTED: protein SMG (1216) 3737 317.0 4.2e-85
XP_011508507 (OMIM: 610964) PREDICTED: protein SMG (1216) 3737 317.0 4.2e-85
XP_005245705 (OMIM: 610964) PREDICTED: protein SMG (1216) 3737 317.0 4.2e-85
XP_011508510 (OMIM: 610964) PREDICTED: protein SMG (1166) 3734 316.8 4.8e-85
XP_016858460 (OMIM: 610964) PREDICTED: protein SMG ( 806) 3684 312.6 5.8e-84
XP_005245710 (OMIM: 610964) PREDICTED: protein SMG (1169) 3680 312.4 9.8e-84
XP_011508509 (OMIM: 610964) PREDICTED: protein SMG (1169) 3680 312.4 9.8e-84
NP_001167532 (OMIM: 610964) protein SMG7 isoform 5 (1145) 3520 299.5 7.4e-80
XP_016858458 (OMIM: 610964) PREDICTED: protein SMG ( 852) 2137 188.0 2.1e-46
XP_016858459 (OMIM: 610964) PREDICTED: protein SMG ( 852) 2137 188.0 2.1e-46
>>NP_963862 (OMIM: 610964) protein SMG7 isoform 2 [Homo (1091 aa)
initn: 7384 init1: 7384 opt: 7384 Z-score: 3238.2 bits: 610.9 E(85289): 1.2e-173
Smith-Waterman score: 7384; 99.9% identity (100.0% similar) in 1091 aa overlap (1-1091:1-1091)
10 20 30 40 50 60
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QANIDRRGKRSPGIFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQ
1030 1040 1050 1060 1070 1080
1090
pF1KSD QRGQGTMNPPH
:::::::::::
NP_963 QRGQGTMNPPH
1090
>>XP_011508511 (OMIM: 610964) PREDICTED: protein SMG7 is (1120 aa)
initn: 7332 init1: 7332 opt: 7333 Z-score: 3215.8 bits: 606.8 E(85289): 2.2e-172
Smith-Waterman score: 7333; 99.4% identity (99.9% similar) in 1089 aa overlap (3-1091:33-1120)
10 20 30
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS
:.:.. .:::::::::::::::::::::::
XP_011 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFEKSLL
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLL
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD EKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLY
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD SLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNR
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD DRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMES
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090
pF1KSD LKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::::::::::::::::::::::::::::::
XP_011 LKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
1090 1100 1110 1120
>>XP_016858456 (OMIM: 610964) PREDICTED: protein SMG7 is (1120 aa)
initn: 7332 init1: 7332 opt: 7333 Z-score: 3215.8 bits: 606.8 E(85289): 2.2e-172
Smith-Waterman score: 7333; 99.4% identity (99.9% similar) in 1089 aa overlap (3-1091:33-1120)
10 20 30
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS
:.:.. .:::::::::::::::::::::::
XP_016 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFEKSLL
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLL
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD EKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLY
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD SLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNR
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD DRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMES
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090
pF1KSD LKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::::::::::::::::::::::::::::::
XP_016 LKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
1090 1100 1110 1120
>>XP_016858457 (OMIM: 610964) PREDICTED: protein SMG7 is (1049 aa)
initn: 7116 init1: 7116 opt: 7116 Z-score: 3121.7 bits: 589.3 E(85289): 3.8e-167
Smith-Waterman score: 7116; 99.9% identity (100.0% similar) in 1049 aa overlap (43-1091:1-1049)
20 30 40 50 60 70
pF1KSD EVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTL
::::::::::::::::::::::::::::::
XP_016 MLVTDLEYALDKKVEQDLWNHAFKNQITTL
10 20 30
80 90 100 110 120 130
pF1KSD QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPY
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD GKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPP
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD VMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSP
760 770 780 790 800 810
860 870 880 890 900 910
pF1KSD GIFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL
820 830 840 850 860 870
920 930 940 950 960 970
pF1KSD TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPT
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KSD HNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPS
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KSD GTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
1000 1010 1020 1030 1040
>>XP_006711741 (OMIM: 610964) PREDICTED: protein SMG7 is (1141 aa)
initn: 7370 init1: 5867 opt: 5879 Z-score: 2582.3 bits: 489.6 E(85289): 4.2e-137
Smith-Waterman score: 7141; 95.5% identity (95.5% similar) in 1123 aa overlap (1-1073:1-1123)
10 20 30 40 50 60
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
790 800 810 820 830 840
850 860
pF1KSD QANIDRRGKRSPGIFRPEQDPVPRMPFE--------------------------------
:::::::::::::.::::::::::::::
XP_006 QANIDRRGKRSPGVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPD
850 860 870 880 890 900
870 880 890 900 910
pF1KSD ------------------KSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK
::::::::::::::::::::::::::::::::::::::::::
XP_006 LYPALLGPLASLPGRSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK
910 920 930 940 950 960
920 930 940 950 960 970
pF1KSD NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KSD PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KSD PSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP
:::::::::::::::::::::::::::::::::::::::::::
XP_006 PSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP
1090 1100 1110 1120 1130 1140
pF1KSD H
XP_006 H
>>NP_963863 (OMIM: 610964) protein SMG7 isoform 4 [Homo (1178 aa)
initn: 7107 init1: 5867 opt: 5879 Z-score: 2582.1 bits: 489.7 E(85289): 4.4e-137
Smith-Waterman score: 7013; 94.5% identity (95.2% similar) in 1116 aa overlap (1-1066:1-1115)
10 20 30 40 50 60
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 IPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQ
790 800 810 820 830 840
850 860
pF1KSD QANIDRRGKRSPGIFRPEQDPVPRMPFE--------------------------------
:::::::::::::.::::::::::::::
NP_963 QANIDRRGKRSPGVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPD
850 860 870 880 890 900
870 880 890 900 910
pF1KSD ------------------KSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK
::::::::::::::::::::::::::::::::::::::::::
NP_963 LYPALLGPLASLPGRSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGK
910 920 930 940 950 960
920 930 940 950 960 970
pF1KSD NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KSD PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQAST
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KSD PSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP
::::::::::::::::::::::::. . .... ::
NP_963 PSGTWTGHGPSMEDSSAVLMESLKK-QQHGVQQLGPKRQSEEEGSSSICVAHRGPRPLPS
1090 1100 1110 1120 1130
pF1KSD H
NP_963 CSLPASTFRVKFKAARTCAHQAQKKTRRRPFWKRRKKGK
1140 1150 1160 1170
>>XP_016858455 (OMIM: 610964) PREDICTED: protein SMG7 is (1170 aa)
initn: 7318 init1: 5815 opt: 5828 Z-score: 2560.0 bits: 485.5 E(85289): 7.5e-136
Smith-Waterman score: 7090; 95.0% identity (95.5% similar) in 1121 aa overlap (3-1073:33-1152)
10 20 30
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS
:.:.. .:::::::::::::::::::::::
XP_016 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
790 800 810 820 830 840
820 830 840 850 860
pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFE----
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_016 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEDPKS
850 860 870 880 890 900
870 880
pF1KSD ----------------------------------------------KSLLEKPSELMSHS
::::::::::::::
XP_016 SPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHS
910 920 930 940 950 960
890 900 910 920 930 940
pF1KSD SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
970 980 990 1000 1010 1020
950 960 970 980 990 1000
pF1KSD SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
1030 1040 1050 1060 1070 1080
1010 1020 1030 1040 1050 1060
pF1KSD DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
1090 1100 1110 1120 1130 1140
1070 1080 1090
pF1KSD HPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::
XP_016 HPGPSALEQLLMQQKQKQQRGQGTMNPPH
1150 1160 1170
>>XP_011508508 (OMIM: 610964) PREDICTED: protein SMG7 is (1170 aa)
initn: 7318 init1: 5815 opt: 5828 Z-score: 2560.0 bits: 485.5 E(85289): 7.5e-136
Smith-Waterman score: 7090; 95.0% identity (95.5% similar) in 1121 aa overlap (3-1073:33-1152)
10 20 30
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS
:.:.. .:::::::::::::::::::::::
XP_011 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
790 800 810 820 830 840
820 830 840 850 860
pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFE----
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_011 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEDPKS
850 860 870 880 890 900
870 880
pF1KSD ----------------------------------------------KSLLEKPSELMSHS
::::::::::::::
XP_011 SPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHS
910 920 930 940 950 960
890 900 910 920 930 940
pF1KSD SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
970 980 990 1000 1010 1020
950 960 970 980 990 1000
pF1KSD SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
1030 1040 1050 1060 1070 1080
1010 1020 1030 1040 1050 1060
pF1KSD DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
1090 1100 1110 1120 1130 1140
1070 1080 1090
pF1KSD HPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::
XP_011 HPGPSALEQLLMQQKQKQQRGQGTMNPPH
1150 1160 1170
>>NP_001317936 (OMIM: 610964) protein SMG7 isoform 6 [Ho (1170 aa)
initn: 7318 init1: 5815 opt: 5828 Z-score: 2560.0 bits: 485.5 E(85289): 7.5e-136
Smith-Waterman score: 7090; 95.0% identity (95.5% similar) in 1121 aa overlap (3-1073:33-1152)
10 20 30
pF1KSD MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTS
:.:.. .:::::::::::::::::::::::
NP_001 NWMFLQIVIVGENVSFKSQMRTENLKSEEHLKSSN-IRQAEVLKADMTDSKLGPAEVWTS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPW
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQP
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYN
790 800 810 820 830 840
820 830 840 850 860
pF1KSD HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGIFRPEQDPVPRMPFE----
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_001 HNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEDPKS
850 860 870 880 890 900
870 880
pF1KSD ----------------------------------------------KSLLEKPSELMSHS
::::::::::::::
NP_001 SPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASLPGRSLFKSLLEKPSELMSHS
910 920 930 940 950 960
890 900 910 920 930 940
pF1KSD SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
970 980 990 1000 1010 1020
950 960 970 980 990 1000
pF1KSD SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
1030 1040 1050 1060 1070 1080
1010 1020 1030 1040 1050 1060
pF1KSD DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
1090 1100 1110 1120 1130 1140
1070 1080 1090
pF1KSD HPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::
NP_001 HPGPSALEQLLMQQKQKQQRGQGTMNPPH
1150 1160 1170
>>XP_011508512 (OMIM: 610964) PREDICTED: protein SMG7 is (1099 aa)
initn: 7102 init1: 5599 opt: 5611 Z-score: 2465.8 bits: 468.0 E(85289): 1.3e-130
Smith-Waterman score: 6873; 95.3% identity (95.4% similar) in 1081 aa overlap (43-1073:1-1081)
20 30 40 50 60 70
pF1KSD EVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTL
::::::::::::::::::::::::::::::
XP_011 MLVTDLEYALDKKVEQDLWNHAFKNQITTL
10 20 30
80 90 100 110 120 130
pF1KSD QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLR
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFR
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPY
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD GKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPP
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD VMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSP
760 770 780 790 800 810
860
pF1KSD GIFRPEQDPVPRMPFE--------------------------------------------
:.::::::::::::::
XP_011 GVFRPEQDPVPRMPFEDPKSSPLLPPDLLKSLAALEEEEELIFSNPPDLYPALLGPLASL
820 830 840 850 860 870
870 880 890 900 910 920
pF1KSD ------KSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGRSLFKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP
880 890 900 910 920 930
930 940 950 960 970 980
pF1KSD SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSN
940 950 960 970 980 990
990 1000 1010 1020 1030 1040
pF1KSD FGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSM
1000 1010 1020 1030 1040 1050
1050 1060 1070 1080 1090
pF1KSD EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
:::::::::::::::::::::::::::::::
XP_011 EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
1060 1070 1080 1090
1091 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:55:15 2016 done: Thu Nov 3 00:55:17 2016
Total Scan time: 14.910 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]