FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0251, 788 aa
1>>>pF1KSDA0251 788 - 788 aa - 788 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3954+/-0.000345; mu= 15.8630+/- 0.022
mean_var=100.1377+/-20.252, 0's: 0 Z-trim(116.2): 55 B-trim: 0 in 0/56
Lambda= 0.128167
statistics sampled from 27098 (27153) to 27098 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.318), width: 16
Scan time: 12.950
The best scores are: opt bits E(85289)
NP_055842 (OMIM: 614244) pyridoxal-dependent decar ( 788) 5203 973.0 0
NP_001310948 (OMIM: 614244) pyridoxal-dependent de ( 787) 5184 969.5 0
XP_016878549 (OMIM: 614244) PREDICTED: pyridoxal-d ( 797) 5169 966.7 0
XP_005255230 (OMIM: 614244) PREDICTED: pyridoxal-d ( 806) 5162 965.4 0
XP_016878548 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1 0
XP_005255233 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1 0
XP_016878550 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1 0
NP_001272376 (OMIM: 614244) pyridoxal-dependent de ( 773) 5112 956.1 0
XP_016878551 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1 0
XP_016878553 (OMIM: 614244) PREDICTED: pyridoxal-d ( 746) 4693 878.7 0
XP_006720928 (OMIM: 614244) PREDICTED: pyridoxal-d ( 746) 4693 878.7 0
NP_001272374 (OMIM: 614244) pyridoxal-dependent de ( 760) 4693 878.7 0
NP_001272373 (OMIM: 614244) pyridoxal-dependent de ( 761) 4693 878.7 0
XP_016878552 (OMIM: 614244) PREDICTED: pyridoxal-d ( 708) 4540 850.4 0
NP_001272377 (OMIM: 614244) pyridoxal-dependent de ( 697) 4365 818.0 0
NP_001272378 (OMIM: 614244) pyridoxal-dependent de ( 498) 3120 587.7 4.1e-167
NP_001310949 (OMIM: 614244) pyridoxal-dependent de ( 497) 3101 584.2 4.7e-166
XP_016878554 (OMIM: 614244) PREDICTED: pyridoxal-d ( 483) 3029 570.9 4.6e-162
NP_001310950 (OMIM: 614244) pyridoxal-dependent de ( 471) 2610 493.4 9.5e-139
NP_001272379 (OMIM: 614244) pyridoxal-dependent de ( 429) 1431 275.3 3.7e-73
>>NP_055842 (OMIM: 614244) pyridoxal-dependent decarboxy (788 aa)
initn: 5203 init1: 5203 opt: 5203 Z-score: 5199.9 bits: 973.0 E(85289): 0
Smith-Waterman score: 5203; 100.0% identity (100.0% similar) in 788 aa overlap (1-788:1-788)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
730 740 750 760 770 780
pF1KSD VEGPESLR
::::::::
NP_055 VEGPESLR
>>NP_001310948 (OMIM: 614244) pyridoxal-dependent decarb (787 aa)
initn: 5009 init1: 5009 opt: 5184 Z-score: 5180.9 bits: 969.5 E(85289): 0
Smith-Waterman score: 5184; 99.9% identity (99.9% similar) in 788 aa overlap (1-788:1-787)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_001 MDASLEKIADPTLAEMGKNLKEAVKMLEDSQR-TEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40 50
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
720 730 740 750 760 770
pF1KSD VEGPESLR
::::::::
NP_001 VEGPESLR
780
>>XP_016878549 (OMIM: 614244) PREDICTED: pyridoxal-depen (797 aa)
initn: 5169 init1: 5169 opt: 5169 Z-score: 5165.8 bits: 966.7 E(85289): 0
Smith-Waterman score: 5169; 99.6% identity (99.7% similar) in 786 aa overlap (3-788:12-797)
10 20 30 40 50
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPL
:: . ::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPERSRSYFRASCKPIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD QGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD KLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD KKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIER
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD CDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD GFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD NMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD GEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD KSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVET
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD IAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWF
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD SPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSL
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD RGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGV
730 740 750 760 770 780
780
pF1KSD PHPEDDHSQVEGPESLR
:::::::::::::::::
XP_016 PHPEDDHSQVEGPESLR
790
>>XP_005255230 (OMIM: 614244) PREDICTED: pyridoxal-depen (806 aa)
initn: 5162 init1: 5162 opt: 5162 Z-score: 5158.8 bits: 965.4 E(85289): 0
Smith-Waterman score: 5162; 99.9% identity (100.0% similar) in 782 aa overlap (7-788:25-806)
10 20 30 40
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKL
.:::::::::::::::::::::::::::::::::::
XP_005 MACSILEGCRREVRRETWKPGPGSEIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD ISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD STLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD VDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD KLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD SSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLW
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD LSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSD
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD PVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD MTAAVLGTRGEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAAVLGTRGEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD VRYEHANDDKSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRYEHANDDKSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDN
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD VDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD VVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD GQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTD
730 740 750 760 770 780
770 780
pF1KSD QTEAFQKGVPHPEDDHSQVEGPESLR
::::::::::::::::::::::::::
XP_005 QTEAFQKGVPHPEDDHSQVEGPESLR
790 800
>>XP_016878548 (OMIM: 614244) PREDICTED: pyridoxal-depen (773 aa)
initn: 5112 init1: 5112 opt: 5112 Z-score: 5109.1 bits: 956.1 E(85289): 0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
710 720 730 740 750 760
pF1KSD VEGPESLR
::::::::
XP_016 VEGPESLR
770
>>XP_005255233 (OMIM: 614244) PREDICTED: pyridoxal-depen (773 aa)
initn: 5112 init1: 5112 opt: 5112 Z-score: 5109.1 bits: 956.1 E(85289): 0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
710 720 730 740 750 760
pF1KSD VEGPESLR
::::::::
XP_005 VEGPESLR
770
>>XP_016878550 (OMIM: 614244) PREDICTED: pyridoxal-depen (773 aa)
initn: 5112 init1: 5112 opt: 5112 Z-score: 5109.1 bits: 956.1 E(85289): 0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
710 720 730 740 750 760
pF1KSD VEGPESLR
::::::::
XP_016 VEGPESLR
770
>>NP_001272376 (OMIM: 614244) pyridoxal-dependent decarb (773 aa)
initn: 5112 init1: 5112 opt: 5112 Z-score: 5109.1 bits: 956.1 E(85289): 0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
710 720 730 740 750 760
pF1KSD VEGPESLR
::::::::
NP_001 VEGPESLR
770
>>XP_016878551 (OMIM: 614244) PREDICTED: pyridoxal-depen (773 aa)
initn: 5112 init1: 5112 opt: 5112 Z-score: 5109.1 bits: 956.1 E(85289): 0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
10 20 30 40
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
710 720 730 740 750 760
pF1KSD VEGPESLR
::::::::
XP_016 VEGPESLR
770
>>XP_016878553 (OMIM: 614244) PREDICTED: pyridoxal-depen (746 aa)
initn: 4689 init1: 4689 opt: 4693 Z-score: 4690.6 bits: 878.7 E(85289): 0
Smith-Waterman score: 4866; 96.5% identity (96.5% similar) in 773 aa overlap (16-788:1-746)
10 20 30 40 50 60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
::::::::::::::::::::::::::::::::::::::
XP_016 MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQG-------
10 20 30
70 80 90 100 110 120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------RIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
40 50 60 70
130 140 150 160 170 180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
80 90 100 110 120 130
190 200 210 220 230 240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
140 150 160 170 180 190
250 260 270 280 290 300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
200 210 220 230 240 250
310 320 330 340 350 360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
260 270 280 290 300 310
370 380 390 400 410 420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
320 330 340 350 360 370
430 440 450 460 470 480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
380 390 400 410 420 430
490 500 510 520 530 540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
440 450 460 470 480 490
550 560 570 580 590 600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
500 510 520 530 540 550
610 620 630 640 650 660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
560 570 580 590 600 610
670 680 690 700 710 720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
620 630 640 650 660 670
730 740 750 760 770 780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
680 690 700 710 720 730
pF1KSD VEGPESLR
::::::::
XP_016 VEGPESLR
740
788 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:55:57 2016 done: Thu Nov 3 00:55:59 2016
Total Scan time: 12.950 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]