FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0263, 441 aa
1>>>pF1KSDA0263 441 - 441 aa - 441 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5119+/-0.000786; mu= 12.0676+/- 0.048
mean_var=88.8354+/-17.420, 0's: 0 Z-trim(109.6): 12 B-trim: 0 in 0/51
Lambda= 0.136076
statistics sampled from 11015 (11024) to 11015 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.339), width: 16
Scan time: 3.190
The best scores are: opt bits E(32554)
CCDS33760.1 IP6K1 gene_id:9807|Hs108|chr3 ( 441) 2991 597.0 1.2e-170
CCDS43092.1 IP6K1 gene_id:9807|Hs108|chr3 ( 276) 1875 377.8 7.3e-105
CCDS34435.1 IP6K3 gene_id:117283|Hs108|chr6 ( 410) 1179 241.3 1.4e-63
CCDS2777.1 IP6K2 gene_id:51447|Hs108|chr3 ( 426) 1156 236.7 3.3e-62
CCDS7250.1 IPMK gene_id:253430|Hs108|chr10 ( 416) 312 71.1 2.4e-12
CCDS54579.1 IP6K2 gene_id:51447|Hs108|chr3 ( 87) 288 66.1 1.6e-11
CCDS33752.1 IP6K2 gene_id:51447|Hs108|chr3 ( 97) 283 65.1 3.5e-11
CCDS54580.1 IP6K2 gene_id:51447|Hs108|chr3 ( 185) 283 65.2 6.2e-11
CCDS54581.1 IP6K2 gene_id:51447|Hs108|chr3 ( 188) 283 65.2 6.2e-11
>>CCDS33760.1 IP6K1 gene_id:9807|Hs108|chr3 (441 aa)
initn: 2991 init1: 2991 opt: 2991 Z-score: 3177.0 bits: 597.0 E(32554): 1.2e-170
Smith-Waterman score: 2991; 100.0% identity (100.0% similar) in 441 aa overlap (1-441:1-441)
10 20 30 40 50 60
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDR
370 380 390 400 410 420
430 440
pF1KSD GYVFGLENLISIMEQMRDENQ
:::::::::::::::::::::
CCDS33 GYVFGLENLISIMEQMRDENQ
430 440
>>CCDS43092.1 IP6K1 gene_id:9807|Hs108|chr3 (276 aa)
initn: 1875 init1: 1875 opt: 1875 Z-score: 1996.1 bits: 377.8 E(32554): 7.3e-105
Smith-Waterman score: 1875; 100.0% identity (100.0% similar) in 276 aa overlap (166-441:1-276)
140 150 160 170 180 190
pF1KSD ASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRM
::::::::::::::::::::::::::::::
CCDS43 MLDGNSGLSSEKISHNPWSLRCHKQQLSRM
10 20 30
200 210 220 230 240 250
pF1KSD RSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 RSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSAT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KSD LGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKL
100 110 120 130 140 150
320 330 340 350 360 370
pF1KSD RGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVASSCGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 RGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVASSCGPS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KSD TSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 TSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQ
220 230 240 250 260 270
440
pF1KSD MRDENQ
::::::
CCDS43 MRDENQ
>>CCDS34435.1 IP6K3 gene_id:117283|Hs108|chr6 (410 aa)
initn: 1361 init1: 791 opt: 1179 Z-score: 1255.0 bits: 241.3 E(32554): 1.4e-63
Smith-Waterman score: 1361; 50.6% identity (72.7% similar) in 433 aa overlap (14-438:4-408)
10 20 30 40 50
pF1KSD MCVCQTMEVGQYGKNASRAGDR--GVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRF
.:.. ::: :: ::::.:::::: :.:.::.:::::::.::::::
CCDS34 MVVQNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KSD YESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHS
::::: ::.:::.:::.:.: . :: :...::: : ::. . .: .
CCDS34 YESLPLAMKRFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD RRSLHRSGSGSDHKE-EKASLSLETSESSQEAKSPKVELHSHSEVP-FQMLDGNSGLSSE
... .:: . .:.:. .:: .: .. . : ..: :.... ..: . :
CCDS34 QQTTGSNGSDCTLAQWPHAQLARSPKESPAKAL---LRSEPHLNTPAFSLVEDTNGNQVE
120 130 140 150 160
180 190 200 210 220 230
pF1KSD KISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDA
. : :::.:.::. .:.:. :: . : ..:::::::: .. .:::::::::::::::::
CCDS34 RKSFNPWGLQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD SAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQY
: :: ::.:::: ::::: ::::.::::::: : ..::..::::: ::.::::.::::.
CCDS34 SEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQF
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD LHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEM
:::: :::.:.:::: .::.: .:.. :.:::::::::::::::.:
CCDS34 LHNGSHLRRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEP------------
290 300 310 320 330
360 370 380 390 400 410
pF1KSD RLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQP----KVDVRMIDFAHSTFKGFRDDP
:: : :.. . .:.:. .:.: :::.:::::::.:.::. ..
CCDS34 ---------PERA----PGSPHPHEAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEH
340 350 360 370 380
420 430 440
pF1KSD TVHDGPDRGYVFGLENLISIMEQMRDENQ
:..:::: ::.::::::: :......
CCDS34 TTYDGPDPGYIFGLENLIRILQDIQEGE
390 400 410
>>CCDS2777.1 IP6K2 gene_id:51447|Hs108|chr3 (426 aa)
initn: 1316 init1: 809 opt: 1156 Z-score: 1230.3 bits: 236.7 E(32554): 3.3e-62
Smith-Waterman score: 1310; 49.3% identity (74.3% similar) in 424 aa overlap (22-440:15-424)
10 20 30 40 50 60
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
.:::::::.::::::: ..:... :.::::. ::..:::
CCDS27 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYE
10 20 30 40 50
70 80 90 100 110
pF1KSD SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYV-ESETVEQDDTTEREQPRRKHSR
.:: ::..:::.::::::: :: : : . :.::: . :. :... : :. : :
CCDS27 TLPAEMRKFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCE-PKSKLLR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD RSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELH----SHSEVPFQMLDGNSGLSS
. ... . :. . .. .. .. :: :.: . ..::: . .. ....::
CCDS27 WTTNKKHHVLE-TEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD EKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDD
. .::::..::.:::.::. ..: :. :::.::::.. ... ::::::::::::::::
CCDS27 QLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD ASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQ
:: :::: :.:::.:::::..::::::::::: .:. . :::.:: ::..::..::.:
CCDS27 ASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD YLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSE
..::: :::.:. :.:.:: :::::::: ::::::::::::::::: : : :: .:
CCDS27 FFHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE-RPEVVLDSDAE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD MRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVH
: : ... . .. . . : :: ::::::::::.: . . .: .::
CCDS27 ------D--LEDLSEESADESAGAYAYKPIGASS---VDVRMIDFAHTTCRLYGEDTVVH
360 370 380 390
420 430 440
pF1KSD DGPDRGYVFGLENLISIMEQMRDENQ
.: : ::.:::..::.:. .. .:.
CCDS27 EGQDAGYIFGLQSLIDIVTEISEESGE
400 410 420
>>CCDS7250.1 IPMK gene_id:253430|Hs108|chr10 (416 aa)
initn: 437 init1: 192 opt: 312 Z-score: 335.0 bits: 71.1 E(32554): 2.4e-12
Smith-Waterman score: 312; 33.1% identity (66.2% similar) in 148 aa overlap (207-354:127-272)
180 190 200 210 220 230
pF1KSD KISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDA
.: ::.:.:.:. ::..:.:.: ... :
CCDS72 DCFDGVLLELRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KSD SAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQY
:.:: .:. : .: : ::.::.. . : .:..:::.:. : ..... ..
CCDS72 SSEKIQQQVSK--YPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTKETIKDGVSRF
160 170 180 190 200 210
300 310 320 330 340 350
pF1KSD LHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEM
.::: ::.: ..:.. . .: : . ::.:::: .:.:. . . :. :.
CCDS72 FHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLA
220 230 240 250 260 270
360 370 380 390 400 410
pF1KSD RLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHD
CCDS72 EKFLSKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHRKIYTKKHHSQTS
280 290 300 310 320 330
>>CCDS54579.1 IP6K2 gene_id:51447|Hs108|chr3 (87 aa)
initn: 285 init1: 285 opt: 288 Z-score: 320.3 bits: 66.1 E(32554): 1.6e-11
Smith-Waterman score: 288; 63.2% identity (91.2% similar) in 57 aa overlap (22-78:15-71)
10 20 30 40 50 60
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
.:::::::.::::::: ..:... :.::::. ::..:::
CCDS54 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYE
10 20 30 40 50
70 80 90 100 110 120
pF1KSD SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
.:: ::..:::.::: .:
CCDS54 TLPAEMRKFTPQYKGDISSHQHGGVFVGEWGSLL
60 70 80
>>CCDS33752.1 IP6K2 gene_id:51447|Hs108|chr3 (97 aa)
initn: 300 init1: 283 opt: 283 Z-score: 314.3 bits: 65.1 E(32554): 3.5e-11
Smith-Waterman score: 283; 64.8% identity (92.6% similar) in 54 aa overlap (22-75:15-68)
10 20 30 40 50 60
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
.:::::::.::::::: ..:... :.::::. ::..:::
CCDS33 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYE
10 20 30 40 50
70 80 90 100 110 120
pF1KSD SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRR
.:: ::..:::.:::
CCDS33 TLPAEMRKFTPQYKGQSQRPLVSWPSLPHFFPWSFPLWPQGSVA
60 70 80 90
>>CCDS54580.1 IP6K2 gene_id:51447|Hs108|chr3 (185 aa)
initn: 301 init1: 283 opt: 283 Z-score: 309.8 bits: 65.2 E(32554): 6.2e-11
Smith-Waterman score: 283; 64.8% identity (92.6% similar) in 54 aa overlap (22-75:70-123)
10 20 30 40 50
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPL
.:::::::.::::::: ..:... :.::::
CCDS54 AGLRCLPHLPAICARRMSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KSD ISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTERE
. ::..:::.:: ::..:::.:::
CCDS54 VPREHQFYETLPAEMRKFTPQYKGKSQLLEGLPHWRGDVRDRGHGRPWQPSLEPSLPPTL
100 110 120 130 140 150
>>CCDS54581.1 IP6K2 gene_id:51447|Hs108|chr3 (188 aa)
initn: 301 init1: 283 opt: 283 Z-score: 309.7 bits: 65.2 E(32554): 6.2e-11
Smith-Waterman score: 283; 64.8% identity (92.6% similar) in 54 aa overlap (22-75:73-126)
10 20 30 40 50
pF1KSD MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPL
.:::::::.::::::: ..:... :.::::
CCDS54 AGLRCLPHLPAICARRMSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPL
50 60 70 80 90 100
60 70 80 90 100 110
pF1KSD ISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTERE
. ::..:::.:: ::..:::.:::
CCDS54 VPREHQFYETLPAEMRKFTPQYKGKSQLLEGLPHWRGDVRDRGHGRPWQPSLEPSLPPTL
110 120 130 140 150 160
441 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:29:31 2016 done: Thu Nov 3 18:29:32 2016
Total Scan time: 3.190 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]