FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0272, 729 aa 1>>>pF1KSDA0272 729 - 729 aa - 729 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5315+/-0.000924; mu= 6.0770+/- 0.056 mean_var=169.2065+/-34.088, 0's: 0 Z-trim(111.6): 23 B-trim: 0 in 0/52 Lambda= 0.098597 statistics sampled from 12514 (12527) to 12514 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.385), width: 16 Scan time: 3.550 The best scores are: opt bits E(32554) CCDS2853.1 BAP1 gene_id:8314|Hs108|chr3 ( 729) 4825 698.7 8.1e-201 CCDS55669.1 UCHL5 gene_id:51377|Hs108|chr1 ( 316) 583 95.1 1.8e-19 CCDS55670.1 UCHL5 gene_id:51377|Hs108|chr1 ( 326) 583 95.1 1.8e-19 CCDS55668.1 UCHL5 gene_id:51377|Hs108|chr1 ( 328) 583 95.1 1.8e-19 CCDS1378.1 UCHL5 gene_id:51377|Hs108|chr1 ( 329) 572 93.5 5.4e-19 >>CCDS2853.1 BAP1 gene_id:8314|Hs108|chr3 (729 aa) initn: 4825 init1: 4825 opt: 4825 Z-score: 3718.8 bits: 698.7 E(32554): 8.1e-201 Smith-Waterman score: 4825; 100.0% identity (100.0% similar) in 729 aa overlap (1-729:1-729) 10 20 30 40 50 60 pF1KSD MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR 670 680 690 700 710 720 pF1KSD SRPYKAKRQ ::::::::: CCDS28 SRPYKAKRQ >>CCDS55669.1 UCHL5 gene_id:51377|Hs108|chr1 (316 aa) initn: 725 init1: 149 opt: 583 Z-score: 463.2 bits: 95.1 E(32554): 1.8e-19 Smith-Waterman score: 644; 40.5% identity (68.2% similar) in 289 aa overlap (2-284:4-272) 10 20 30 40 50 pF1KSD MNKG-WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIE : : : .:::::.:: :.. :: .:.:::::..:. . ::.:.:::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD ERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTL .. ::..:. ....:::.:.: :.:::.:..::::::. : :: :: CCDS55 GEEPA---------GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETL 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVS :..:.:...:. :: :..:. . ..::: :: . .. : .... .:::::: CCDS55 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVS 120 130 140 150 160 180 190 200 210 220 230 pF1KSD YVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMA :::..:::.:::::. ::: : ..:. : . .: :: .:: . :: ::::::: CCDS55 YVPVNGRLYELDGLREGPIDLGACNQDD-WISAVRPVIEKRIQKYSEGE----IRFNLMA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD VVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKS .: ::.. :: . . ...:: . : .. .. ::.. .....: :: CCDS55 IVSDRKMIYEQK--IAELQRQLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD PLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTP CCDS55 KIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKGK 290 300 310 >>CCDS55670.1 UCHL5 gene_id:51377|Hs108|chr1 (326 aa) initn: 725 init1: 149 opt: 583 Z-score: 463.0 bits: 95.1 E(32554): 1.8e-19 Smith-Waterman score: 644; 40.5% identity (68.2% similar) in 289 aa overlap (2-284:4-272) 10 20 30 40 50 pF1KSD MNKG-WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIE : : : .:::::.:: :.. :: .:.:::::..:. . ::.:.:::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD ERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTL .. ::..:. ....:::.:.: :.:::.:..::::::. : :: :: CCDS55 GEEPA---------GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETL 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVS :..:.:...:. :: :..:. . ..::: :: . .. : .... .:::::: CCDS55 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVS 120 130 140 150 160 180 190 200 210 220 230 pF1KSD YVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMA :::..:::.:::::. ::: : ..:. : . .: :: .:: . :: ::::::: CCDS55 YVPVNGRLYELDGLREGPIDLGACNQDD-WISAVRPVIEKRIQKYSEGE----IRFNLMA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD VVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKS .: ::.. :: . . ...:: . : .. .. ::.. .....: :: CCDS55 IVSDRKMIYEQK--IAELQRQLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD PLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTP CCDS55 KIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKFEKHFEKTLLGK 290 300 310 320 >>CCDS55668.1 UCHL5 gene_id:51377|Hs108|chr1 (328 aa) initn: 725 init1: 149 opt: 583 Z-score: 463.0 bits: 95.1 E(32554): 1.8e-19 Smith-Waterman score: 644; 40.5% identity (68.2% similar) in 289 aa overlap (2-284:4-272) 10 20 30 40 50 pF1KSD MNKG-WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIE : : : .:::::.:: :.. :: .:.:::::..:. . ::.:.:::::: CCDS55 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD ERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTL .. ::..:. ....:::.:.: :.:::.:..::::::. : :: :: CCDS55 GEEPA---------GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETL 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVS :..:.:...:. :: :..:. . ..::: :: . .. : .... .:::::: CCDS55 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVS 120 130 140 150 160 180 190 200 210 220 230 pF1KSD YVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMA :::..:::.:::::. ::: : ..:. : . .: :: .:: . :: ::::::: CCDS55 YVPVNGRLYELDGLREGPIDLGACNQDD-WISAVRPVIEKRIQKYSEGE----IRFNLMA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD VVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKS .: ::.. :: . . ...:: . : .. .. ::.. .....: :: CCDS55 IVSDRKMIYEQK--IAELQRQLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRY 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD PLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTP CCDS55 KIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 290 300 310 320 >>CCDS1378.1 UCHL5 gene_id:51377|Hs108|chr1 (329 aa) initn: 725 init1: 149 opt: 572 Z-score: 454.5 bits: 93.5 E(32554): 5.4e-19 Smith-Waterman score: 633; 43.1% identity (68.7% similar) in 262 aa overlap (2-257:4-245) 10 20 30 40 50 pF1KSD MNKG-WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIE : : : .:::::.:: :.. :: .:.:::::..:. . ::.:.:::::: CCDS13 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD ERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTL .. ::..:. ....:::.:.: :.:::.:..::::::. : :: :: CCDS13 GEEPA---------GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETL 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVS :..:.:...:. :: :..:. . ..::: :: . .. : .... .:::::: CCDS13 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVS 120 130 140 150 160 180 190 200 210 220 230 pF1KSD YVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMA :::..:::.:::::. ::: : ..:. : . .: :: .:: . :: ::::::: CCDS13 YVPVNGRLYELDGLREGPIDLGACNQDD-WISAVRPVIEKRIQKYSEGE----IRFNLMA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD VVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKS .: ::.. :: .. :. :: . : CCDS13 IVSDRKMIYEQKIAELQ--RQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKR 230 240 250 260 270 280 729 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:01:19 2016 done: Thu Nov 3 01:01:19 2016 Total Scan time: 3.550 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]