Result of FASTA (omim) for
pF1KSDA0275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0275, 424 aa
1>>>pF1KSDA0275 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8260+/-0.000326; mu= 10.6072+/- 0.020
mean_var=121.0661+/-23.317, 0's: 0 Z-trim(118.9): 94 B-trim: 71 in 1/53
Lambda= 0.116564
statistics sampled from 32148 (32249) to 32148 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.378), width: 16
Scan time: 8.760
The best scores are: opt bits E(85289)
NP_055582 (OMIM: 607988) testican-2 isoform 2 prec ( 424) 3005 516.3 5.8e-146
NP_001231879 (OMIM: 607988) testican-2 isoform 2 p ( 424) 3005 516.3 5.8e-146
XP_011538706 (OMIM: 607988) PREDICTED: testican-2 ( 421) 2972 510.7 2.7e-144
XP_011530320 (OMIM: 607989) PREDICTED: testican-3 ( 436) 1444 253.8 6.2e-67
NP_058646 (OMIM: 607989) testican-3 isoform 2 prec ( 436) 1444 253.8 6.2e-67
XP_016863747 (OMIM: 607989) PREDICTED: testican-3 ( 433) 1411 248.3 2.9e-65
NP_001035249 (OMIM: 607989) testican-3 isoform 1 p ( 433) 1411 248.3 2.9e-65
XP_016863746 (OMIM: 607989) PREDICTED: testican-3 ( 445) 1411 248.3 3e-65
NP_004589 (OMIM: 602264) testican-1 precursor [Hom ( 439) 1317 232.4 1.7e-60
NP_001191281 (OMIM: 607989) testican-3 isoform 3 [ ( 385) 1270 224.5 3.6e-58
NP_001191283 (OMIM: 607989) testican-3 isoform 5 [ ( 344) 1161 206.1 1.1e-52
NP_001191287 (OMIM: 607989) testican-3 isoform 9 p ( 313) 1067 190.3 5.8e-48
NP_001191284 (OMIM: 607989) testican-3 isoform 6 [ ( 340) 1025 183.3 8.3e-46
NP_001191282 (OMIM: 607989) testican-3 isoform 4 [ ( 316) 1024 183.1 8.8e-46
NP_001238896 (OMIM: 607989) testican-3 isoform 11 ( 338) 926 166.6 8.5e-41
NP_001191285 (OMIM: 607989) testican-3 isoform 7 p ( 393) 695 127.8 4.7e-29
XP_016872474 (OMIM: 607988) PREDICTED: testican-2 ( 77) 432 83.1 2.7e-16
NP_001127906 (OMIM: 607988) testican-2 isoform 1 p ( 77) 432 83.1 2.7e-16
NP_001159884 (OMIM: 125400,607223) SPARC-related m ( 446) 225 48.8 3.3e-05
XP_011534368 (OMIM: 125400,607223) PREDICTED: SPAR ( 464) 225 48.8 3.4e-05
NP_071421 (OMIM: 125400,607223) SPARC-related modu ( 457) 209 46.1 0.00021
XP_011534367 (OMIM: 125400,607223) PREDICTED: SPAR ( 475) 209 46.1 0.00022
NP_002499 (OMIM: 131390) nidogen-1 precursor [Homo (1247) 215 47.4 0.00024
NP_002169 (OMIM: 146735) insulin-like growth facto ( 240) 194 43.4 0.00074
XP_011542497 (OMIM: 131390) PREDICTED: nidogen-1 i (1205) 205 45.7 0.00074
NP_001020330 (OMIM: 142790) HLA class II histocomp ( 296) 194 43.5 0.00087
XP_016865578 (OMIM: 142790) PREDICTED: HLA class I ( 321) 194 43.5 0.00093
NP_001013416 (OMIM: 146732) insulin-like growth fa ( 297) 187 42.3 0.002
NP_071420 (OMIM: 206920,608488) SPARC-related modu ( 434) 188 42.6 0.0024
NP_001030024 (OMIM: 206920,608488) SPARC-related m ( 435) 188 42.6 0.0024
XP_005268053 (OMIM: 206920,608488) PREDICTED: SPAR ( 445) 186 42.3 0.0031
XP_005268052 (OMIM: 206920,608488) PREDICTED: SPAR ( 446) 186 42.3 0.0031
XP_016867641 (OMIM: 146732) PREDICTED: insulin-lik ( 291) 183 41.6 0.0031
NP_000589 (OMIM: 146732) insulin-like growth facto ( 291) 183 41.6 0.0031
NP_001278905 (OMIM: 606041) SPARC-like protein 1 i ( 539) 179 41.1 0.0081
NP_001278906 (OMIM: 606041) SPARC-like protein 1 i ( 539) 179 41.1 0.0081
NP_000590 (OMIM: 146734) insulin-like growth facto ( 272) 173 39.9 0.0094
NP_004675 (OMIM: 606041) SPARC-like protein 1 isof ( 664) 179 41.2 0.0095
NP_001121782 (OMIM: 606041) SPARC-like protein 1 i ( 664) 179 41.2 0.0095
>>NP_055582 (OMIM: 607988) testican-2 isoform 2 precurso (424 aa)
initn: 3005 init1: 3005 opt: 3005 Z-score: 2741.5 bits: 516.3 E(85289): 5.8e-146
Smith-Waterman score: 3005; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
370 380 390 400 410 420
pF1KSD GYIW
::::
NP_055 GYIW
>>NP_001231879 (OMIM: 607988) testican-2 isoform 2 precu (424 aa)
initn: 3005 init1: 3005 opt: 3005 Z-score: 2741.5 bits: 516.3 E(85289): 5.8e-146
Smith-Waterman score: 3005; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
370 380 390 400 410 420
pF1KSD GYIW
::::
NP_001 GYIW
>>XP_011538706 (OMIM: 607988) PREDICTED: testican-2 isof (421 aa)
initn: 2559 init1: 2559 opt: 2972 Z-score: 2711.5 bits: 510.7 E(85289): 2.7e-144
Smith-Waterman score: 2972; 99.3% identity (99.3% similar) in 424 aa overlap (1-424:1-421)
10 20 30 40 50 60
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRD---DDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
70 80 90 100 110
130 140 150 160 170 180
pF1KSD IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
360 370 380 390 400 410
pF1KSD GYIW
::::
XP_011 GYIW
420
>>XP_011530320 (OMIM: 607989) PREDICTED: testican-3 isof (436 aa)
initn: 849 init1: 559 opt: 1444 Z-score: 1322.6 bits: 253.8 E(85289): 6.2e-67
Smith-Waterman score: 1444; 49.5% identity (73.6% similar) in 416 aa overlap (15-421:20-429)
10 20 30 40 50
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKI
: ::::.: : : ..: :::..:.:::..::::. ..
XP_011 MLKVSAVLCVCAAAWCSQSLAAAAAVAA--AGGRSDG---GNFLDDKQWLTTISQYDKEV
10 20 30 40 50
60 70 80 90 100 110
pF1KSD KHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRK
.::.:::::::::...: .. :.::: .:::: :.::::::::::: : :.:::..
XP_011 GQWNKFRDEVEDDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD KLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL
.: ::.:. : . .: : :: : .. . :::::::::: :::: :::. .::.
XP_011 RLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD AVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVA
.:.::: ::::... :::. . ..:. .. ....::::::. :::...:: .....
XP_011 SVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDT
: : .: :. ::::.::::..:::. ::.:::.:: .: ::: : : . :::::::
XP_011 RPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD YKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQ
:::. .:. :::.:: :.. ::: .:: :: ....:: : .:: :::::::. ::
XP_011 YKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD SSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV--GWEDEEEKETEEAGEE--
: :.:::::. : :. :.: .: :: .::::.:: : :.:. : . ..:
XP_011 SVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE
360 370 380 390 400 410
410 420
pF1KSD AEEEEGEAGEADDGGYIW
:... . :. ::::
XP_011 IEDDDEDEGDDDDGGDDHDVYI
420 430
>>NP_058646 (OMIM: 607989) testican-3 isoform 2 precurso (436 aa)
initn: 849 init1: 559 opt: 1444 Z-score: 1322.6 bits: 253.8 E(85289): 6.2e-67
Smith-Waterman score: 1444; 49.5% identity (73.6% similar) in 416 aa overlap (15-421:20-429)
10 20 30 40 50
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKI
: ::::.: : : ..: :::..:.:::..::::. ..
NP_058 MLKVSAVLCVCAAAWCSQSLAAAAAVAA--AGGRSDG---GNFLDDKQWLTTISQYDKEV
10 20 30 40 50
60 70 80 90 100 110
pF1KSD KHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRK
.::.:::::::::...: .. :.::: .:::: :.::::::::::: : :.:::..
NP_058 GQWNKFRDEVEDDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD KLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL
.: ::.:. : . .: : :: : .. . :::::::::: :::: :::. .::.
NP_058 RLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD AVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVA
.:.::: ::::... :::. . ..:. .. ....::::::. :::...:: .....
NP_058 SVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDT
: : .: :. ::::.::::..:::. ::.:::.:: .: ::: : : . :::::::
NP_058 RPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD YKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQ
:::. .:. :::.:: :.. ::: .:: :: ....:: : .:: :::::::. ::
NP_058 YKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD SSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV--GWEDEEEKETEEAGEE--
: :.:::::. : :. :.: .: :: .::::.:: : :.:. : . ..:
NP_058 SVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE
360 370 380 390 400 410
410 420
pF1KSD AEEEEGEAGEADDGGYIW
:... . :. ::::
NP_058 IEDDDEDEGDDDDGGDDHDVYI
420 430
>>XP_016863747 (OMIM: 607989) PREDICTED: testican-3 isof (433 aa)
initn: 639 init1: 612 opt: 1411 Z-score: 1292.7 bits: 248.3 E(85289): 2.9e-65
Smith-Waterman score: 1411; 48.8% identity (72.8% similar) in 416 aa overlap (15-421:20-426)
10 20 30 40 50
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKI
: ::::.: : : ..: :::..:.:::..::::. ..
XP_016 MLKVSAVLCVCAAAWCSQSLAAAAAVAA--AGGRSDG---GNFLDDKQWLTTISQYDKEV
10 20 30 40 50
60 70 80 90 100 110
pF1KSD KHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRK
.::.::: :::...: .. :.::: .:::: :.::::::::::: : :.:::..
XP_016 GQWNKFRD---DDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD KLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL
.: ::.:. : . .: : :: : .. . :::::::::: :::: :::. .::.
XP_016 RLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD AVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVA
.:.::: ::::... :::. . ..:. .. ....::::::. :::...:: .....
XP_016 SVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDT
: : .: :. ::::.::::..:::. ::.:::.:: .: ::: : : . :::::::
XP_016 RPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD YKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQ
:::. .:. :::.:: :.. ::: .:: :: ....:: : .:: :::::::. ::
XP_016 YKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD SSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV--GWEDEEEKETEEAGEE--
: :.:::::. : :. :.: .: :: .::::.:: : :.:. : . ..:
XP_016 SVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE
360 370 380 390 400 410
410 420
pF1KSD AEEEEGEAGEADDGGYIW
:... . :. ::::
XP_016 IEDDDEDEGDDDDGGDDHDVYI
420 430
>>NP_001035249 (OMIM: 607989) testican-3 isoform 1 precu (433 aa)
initn: 639 init1: 612 opt: 1411 Z-score: 1292.7 bits: 248.3 E(85289): 2.9e-65
Smith-Waterman score: 1411; 48.8% identity (72.8% similar) in 416 aa overlap (15-421:20-426)
10 20 30 40 50
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKI
: ::::.: : : ..: :::..:.:::..::::. ..
NP_001 MLKVSAVLCVCAAAWCSQSLAAAAAVAA--AGGRSDG---GNFLDDKQWLTTISQYDKEV
10 20 30 40 50
60 70 80 90 100 110
pF1KSD KHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRK
.::.::: :::...: .. :.::: .:::: :.::::::::::: : :.:::..
NP_001 GQWNKFRD---DDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD KLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQL
.: ::.:. : . .: : :: : .. . :::::::::: :::: :::. .::.
NP_001 RLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD AVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVA
.:.::: ::::... :::. . ..:. .. ....::::::. :::...:: .....
NP_001 SVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDT
: : .: :. ::::.::::..:::. ::.:::.:: .: ::: : : . :::::::
NP_001 RPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD YKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQ
:::. .:. :::.:: :.. ::: .:: :: ....:: : .:: :::::::. ::
NP_001 YKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD SSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV--GWEDEEEKETEEAGEE--
: :.:::::. : :. :.: .: :: .::::.:: : :.:. : . ..:
NP_001 SVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDE
360 370 380 390 400 410
410 420
pF1KSD AEEEEGEAGEADDGGYIW
:... . :. ::::
NP_001 IEDDDEDEGDDDDGGDDHDVYI
420 430
>>XP_016863746 (OMIM: 607989) PREDICTED: testican-3 isof (445 aa)
initn: 639 init1: 612 opt: 1411 Z-score: 1292.5 bits: 248.3 E(85289): 3e-65
Smith-Waterman score: 1411; 48.8% identity (72.8% similar) in 416 aa overlap (15-421:32-438)
10 20 30 40
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQW
: ::::.: : : ..: :::..:.::
XP_016 PPHPPLCLLSQMLKVSAVLCVCAAAWCSQSLAAAAAVAA--AGGRSDG---GNFLDDKQW
10 20 30 40 50
50 60 70 80 90 100
pF1KSD LSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQ
:..::::. .. .::.::: :::...: .. :.::: .:::: :.:::::::::::
XP_016 LTTISQYDKEVGQWNKFRD---DDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KSD GYQRAMCISRKKLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKL
: :.:::...: ::.:. : . .: : :: : .. . :::::::::: :::
XP_016 DSQTAVCISHRRLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KSD EQQACLSSKQLAVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHEN
: :::. .::..:.::: ::::... :::. . ..:. .. ....::::::. :::.
XP_016 EYQACVLGKQISVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLRDWFKALHES
180 190 200 210 220 230
230 240 250 260 270 280
pF1KSD SKQNGSASSVAGPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEV
..:: ..... : : .: :. ::::.::::..:::. ::.:::.:: .: ::: :
XP_016 GSQNKKTKTLLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQ
240 250 260 270 280 290
290 300 310 320 330
pF1KSD CIRPFFNSCDTYKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKPGIFIPSCDE
: . ::::::::::. .:. :::.:: :.. ::: .:: :: ....:: : .:: :::
XP_016 CTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KSD DGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV--GWEDEEE
::::. :: : :.:::::. : :. :.: .: :: .::::.:: : :.:.
XP_016 DGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDED
360 370 380 390 400 410
400 410 420
pF1KSD KETEEAGEE--AEEEEGEAGEADDGGYIW
: . ..: :... . :. ::::
XP_016 DEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVYI
420 430 440
>>NP_004589 (OMIM: 602264) testican-1 precursor [Homo sa (439 aa)
initn: 709 init1: 427 opt: 1317 Z-score: 1207.1 bits: 232.4 E(85289): 1.7e-60
Smith-Waterman score: 1333; 46.6% identity (70.4% similar) in 425 aa overlap (25-424:25-439)
10 20 30 40 50 60
pF1KSD MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
:: . : . :::....::::..:::. . :.:::
NP_004 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNR
10 20 30 40 50
70 80 90 100 110 120
pF1KSD FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
::: :::...:. :. :.::: .:::: ::::: ::::..: :: :.:.:::.: :
NP_004 FRD---DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPR
60 70 80 90 100 110
130 140 150 160 170
pF1KSD IKQPTV-KLH--GNKDSI-CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRC
:. .: . : : .. . :::: .:: : :::::::.:.: :::: .:: ..:.::. :
NP_004 QKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD EGPCPC-PTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPA
.::::: : . :. . .:: ..: .:..::.::: :::.... . .:
NP_004 DGPCPCLPEPEPPKHKAERS--ACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDG
. .: :. ::::.::::.::: . ::.:: .:. :: ::::: ::.:.:::::..:::
NP_004 GRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD RVSTAEWCFCFWREKP---PCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSS
..:. :::.:: .:: :: :..::: .:. : ::: :.:.:::. :: :.
NP_004 KLSNNEWCYCF--QKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGST
300 310 320 330 340 350
360 370 380 390
pF1KSD GDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSG--------------VGWEDEEEK
:.:::::. : ::.:.: .:. .:.. ::::::: .: .:.: :
NP_004 GQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGK
360 370 380 390 400 410
400 410 420
pF1KSD ---ETEEAGEEAEEEEGEAGEADDGGYIW
.:. . :. :.:. . . :. ::::
NP_004 LRVHTRAVTEDDEDEDDD--KEDEVGYIW
420 430
>>NP_001191281 (OMIM: 607989) testican-3 isoform 3 [Homo (385 aa)
initn: 734 init1: 559 opt: 1270 Z-score: 1165.2 bits: 224.5 E(85289): 3.6e-58
Smith-Waterman score: 1270; 48.8% identity (72.9% similar) in 365 aa overlap (66-421:15-378)
40 50 60 70 80 90
pF1KSD GNFMEDEQWLSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKC
.:::...: .. :.::: .:::: :.::
NP_001 MITQDHIHMSSGLSQDDYFRTWSPGKPFDQALDPAKDPCLKMKC
10 20 30 40
100 110 120 130 140 150
pF1KSD SRHKVCIAQGYQRAMCISRKKLEHRIKQPTV---KLHGNKDSICKPCHMAQLASVCGSDG
::::::::: : :.:::...: ::.:. : . .: : :: : .. . ::::::
NP_001 SRHKVCIAQDSQTAVCISHRRLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDG
50 60 70 80 90 100
160 170 180 190 200 210
pF1KSD HTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADGKPETCTGQDLADLGDRLR
:::: :::: :::. .::..:.::: ::::... :::. . ..:. .. ....:::
NP_001 HTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKP-TSTSRNVKRACSDLEFREVANRLR
110 120 130 140 150 160
220 230 240 250 260 270
pF1KSD DWFQLLHENSKQNGSASSVAGPA-SGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELA
:::. :::...:: ..... : : .: :. ::::.::::..:::. ::.:::.::
NP_001 DWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELR
170 180 190 200 210 220
280 290 300 310 320 330
pF1KSD AINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREK-PPCLAELERIQIQEAAKKKP
.: ::: : : . ::::::::::. .:. :::.:: :.. ::: .:: :: ....::
NP_001 SIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLL
230 240 250 260 270 280
340 350 360 370 380 390
pF1KSD GIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSGV
: .:: :::::::. :: : :.:::::. : :. :.: .: :: .::::.::
NP_001 GQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGD
290 300 310 320 330 340
400 410 420
pF1KSD --GWEDEEEKETEEAGEE--AEEEEGEAGEADDGGYIW
: :.:. : . ..: :... . :. ::::
NP_001 FHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVYI
350 360 370 380
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:03:08 2016 done: Thu Nov 3 01:03:09 2016
Total Scan time: 8.760 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]