Result of FASTA (omim) for pF1KSDA0282
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0282, 664 aa
  1>>>pF1KSDA0282 664 - 664 aa - 664 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2280+/-0.000396; mu= 7.0013+/- 0.025
 mean_var=188.0698+/-39.441, 0's: 0 Z-trim(118.9): 138  B-trim: 702 in 1/54
 Lambda= 0.093522
 statistics sampled from 32108 (32262) to 32108 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.378), width:  16
 Scan time: 10.900

The best scores are:                                      opt bits E(85289)
NP_055978 (OMIM: 606555) E3 ubiquitin-protein liga ( 710) 4566 628.9 1.9e-179
XP_016876434 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 710) 4566 628.9 1.9e-179
XP_016876435 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 706) 4523 623.1 1.1e-177
XP_016876436 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 692) 4275 589.6 1.2e-167
XP_016876437 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 688) 4232 583.8 6.9e-166
XP_005267359 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 714) 3808 526.6 1.2e-148
NP_443210 (OMIM: 606555) E3 ubiquitin-protein liga ( 550) 3691 510.8 5.5e-144
XP_016876433 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 732) 3692 511.0 6.2e-144
XP_005267358 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 777) 3691 510.9 7.1e-144
XP_006720081 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 795) 3691 510.9 7.2e-144
XP_016876432 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 791) 3648 505.1  4e-142
XP_011534691 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 802) 3648 505.1 4.1e-142
XP_016876439 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 593) 3027 421.2 5.4e-117
XP_016876438 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 611) 3027 421.2 5.5e-117
NP_001287818 (OMIM: 610584) tripartite motif-conta ( 721) 2411 338.2 6.5e-92
NP_001004342 (OMIM: 610584) tripartite motif-conta ( 783) 2387 334.9 6.6e-91
XP_016856812 (OMIM: 610584) PREDICTED: tripartite  ( 854) 2387 335.0   7e-91
XP_011542494 (OMIM: 610584) PREDICTED: tripartite  ( 781) 2381 334.1 1.2e-90
NP_001287688 (OMIM: 609317) E3 ubiquitin-protein l ( 716)  610 95.2 9.2e-19
NP_061170 (OMIM: 609317) E3 ubiquitin-protein liga ( 728)  610 95.2 9.3e-19
XP_016865111 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 733)  607 94.8 1.2e-18
XP_016865110 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 745)  607 94.8 1.3e-18
XP_016865112 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 529)  596 93.2 2.7e-18
XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685)  562 88.7 7.9e-17
NP_438112 (OMIM: 300204,300928) probable E3 ubiqui ( 705)  562 88.7 8.1e-17
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552)  558 88.1 9.7e-17
NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667)  558 88.1 1.1e-16
NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667)  558 88.1 1.1e-16
XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667)  558 88.1 1.1e-16
NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667)  558 88.1 1.1e-16
NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667)  558 88.1 1.1e-16
XP_005262119 (OMIM: 300204,300928) PREDICTED: prob ( 715)  507 81.3 1.4e-14
NP_036348 (OMIM: 300204,300928) probable E3 ubiqui ( 735)  507 81.3 1.4e-14
NP_001287681 (OMIM: 609317) E3 ubiquitin-protein l ( 573)  487 78.5 7.7e-14
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489)  482 77.8 1.1e-13
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489)  482 77.8 1.1e-13
XP_011543828 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_006724555 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_016885023 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_011543829 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_005274594 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_011543827 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
XP_005274593 (OMIM: 189960,300000,300552) PREDICTE ( 718)  419 69.4 5.3e-11
NP_001269307 (OMIM: 600986) tripartite motif-conta ( 633)  402 67.1 2.3e-10
XP_016885030 (OMIM: 189960,300000,300552) PREDICTE ( 540)  342 58.9 5.7e-08
NP_001180207 (OMIM: 189960,300000,300552) E3 ubiqu ( 540)  342 58.9 5.7e-08
NP_997279 (OMIM: 616923) RING finger protein 207 [ ( 634)  315 55.3   8e-07
XP_016856748 (OMIM: 616923) PREDICTED: RING finger ( 656)  315 55.3 8.2e-07
NP_115977 (OMIM: 606131) E3 ubiquitin-protein liga ( 353)  296 52.6   3e-06
XP_016858048 (OMIM: 606131) PREDICTED: E3 ubiquiti ( 379)  296 52.6 3.2e-06


>>NP_055978 (OMIM: 606555) E3 ubiquitin-protein ligase T  (710 aa)
 initn: 4566 init1: 4566 opt: 4566  Z-score: 3342.6  bits: 628.9 E(85289): 1.9e-179
Smith-Waterman score: 4566; 99.8% identity (100.0% similar) in 661 aa overlap (1-661:1-661)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKNLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_055 MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF
              610       620       630       640       650       660

                                                         
pF1KSD FYQR                                              
       :                                                 
NP_055 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
              670       680       690       700       710

>>XP_016876434 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (710 aa)
 initn: 4566 init1: 4566 opt: 4566  Z-score: 3342.6  bits: 628.9 E(85289): 1.9e-179
Smith-Waterman score: 4566; 99.8% identity (100.0% similar) in 661 aa overlap (1-661:1-661)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKNLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF
              610       620       630       640       650       660

                                                         
pF1KSD FYQR                                              
       :                                                 
XP_016 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
              670       680       690       700       710

>>XP_016876435 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (706 aa)
 initn: 4527 init1: 3026 opt: 4523  Z-score: 3311.2  bits: 623.1 E(85289): 1.1e-177
Smith-Waterman score: 4523; 99.2% identity (99.4% similar) in 661 aa overlap (1-661:1-657)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       :::::::::::::::    :::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSIHQLDFVQVK----VPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430           440       450       460       470      

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
        480       490       500       510       520       530      

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
        540       550       560       570       580       590      

              610       620       630       640       650       660
pF1KSD MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKNLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF
        600       610       620       630       640       650      

                                                         
pF1KSD FYQR                                              
       :                                                 
XP_016 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
        660       670       680       690       700      

>>XP_016876436 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (692 aa)
 initn: 4442 init1: 4275 opt: 4275  Z-score: 3130.5  bits: 589.6 E(85289): 1.2e-167
Smith-Waterman score: 4380; 97.0% identity (97.3% similar) in 661 aa overlap (1-661:1-643)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKNLTF
       :::::::::::::::::.                  ::::::::::::::::.:::::::
XP_016 MDVMKDVMLGKDDKAWAI------------------TEGGITKGATIGVLLDLNRKNLTF
              610                         620       630       640  

                                                         
pF1KSD FYQR                                              
       :                                                 
XP_016 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
            650       660       670       680       690  

>>XP_016876437 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (688 aa)
 initn: 4373 init1: 3026 opt: 4232  Z-score: 3099.2  bits: 583.8 E(85289): 6.9e-166
Smith-Waterman score: 4337; 96.4% identity (96.7% similar) in 661 aa overlap (1-661:1-639)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       :::::::::::::::    :::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSIHQLDFVQVK----VPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430           440       450       460       470      

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
        480       490       500       510       520       530      

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
        540       550       560       570       580       590      

              610       620       630       640       650       660
pF1KSD MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKNLTF
       :::::::::::::::::.                  ::::::::::::::::.:::::::
XP_016 MDVMKDVMLGKDDKAWAI------------------TEGGITKGATIGVLLDLNRKNLTF
        600       610                         620       630        

                                                         
pF1KSD FYQR                                              
       :                                                 
XP_016 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
      640       650       660       670       680        

>>XP_005267359 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (714 aa)
 initn: 4398 init1: 3691 opt: 3808  Z-score: 2789.8  bits: 526.6 E(85289): 1.2e-148
Smith-Waterman score: 4326; 93.9% identity (94.1% similar) in 683 aa overlap (1-661:1-665)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_005 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGCNFET
              490       500       510       520       530       540

                          540       550       560       570        
pF1KSD ----------------VAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSAPYSQLVDIKKLLAVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI
              550       560       570       580       590       600

      580       590       600       610       620       630        
pF1KSD HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTE
       :::::::::::::::::::::::::::::::::::::::.                  ::
XP_005 HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAI------------------TE
              610       620       630       640                    

      640       650       660                                      
pF1KSD GGITKGATIGVLLDFNRKNLTFFYQR                                  
       ::::::::::::::.::::::::                                     
XP_005 GGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLP
            650       660       670       680       690       700  

>>NP_443210 (OMIM: 606555) E3 ubiquitin-protein ligase T  (550 aa)
 initn: 3691 init1: 3691 opt: 3691  Z-score: 2706.1  bits: 510.8 E(85289): 5.5e-144
Smith-Waterman score: 3691; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_443 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGKALQQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
                                                                   
NP_443 YPSERELRGI                                                  
              550                                                  

>>XP_016876433 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (732 aa)
 initn: 4552 init1: 3691 opt: 3692  Z-score: 2705.1  bits: 511.0 E(85289): 6.2e-144
Smith-Waterman score: 4512; 96.6% identity (96.8% similar) in 683 aa overlap (1-661:1-683)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGCNFET
              490       500       510       520       530       540

                          540       550       560       570        
pF1KSD ----------------VAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSAPYSQLVDIKKLLAVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI
              550       560       570       580       590       600

      580       590       600       610       620       630        
pF1KSD HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTE
              610       620       630       640       650       660

      640       650       660                                      
pF1KSD GGITKGATIGVLLDFNRKNLTFFYQR                                  
       ::::::::::::::.::::::::                                     
XP_016 GGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLP
              670       680       690       700       710       720

>>XP_005267358 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (777 aa)
 initn: 4398 init1: 3691 opt: 3691  Z-score: 2704.0  bits: 510.9 E(85289): 7.1e-144
Smith-Waterman score: 4046; 87.8% identity (87.8% similar) in 696 aa overlap (1-611:1-696)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_005 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEDTDSEE
              490       500       510       520       530       540

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_005 QTLPFPVPSERLPLRRMSPFSSTLNLQPSFPGRSYFDFRSSPHQLSLHSSLQSLNAPGCN
              550       560       570       580       590       600

                             540       550       560       570     
pF1KSD -------------------VAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFS
                          :::::::::::::::::::::::::::::::::::::::::
XP_005 FETQSAPYSQLVDIKKLLAVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFS
              610       620       630       640       650       660

         580       590       600       610       620       630     
pF1KSD KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTN
       ::::::::::::::::::::::::::::::::::::                        
XP_005 KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAITEGGITKGATIGVLLDL
              670       680       690       700       710       720

         640       650       660                                
pF1KSD RTEGGITKGATIGVLLDFNRKNLTFFYQR                            
                                                                
XP_005 NRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
              730       740       750       760       770       

>>XP_006720081 (OMIM: 606555) PREDICTED: E3 ubiquitin-pr  (795 aa)
 initn: 4552 init1: 3691 opt: 3691  Z-score: 2703.8  bits: 510.9 E(85289): 7.2e-144
Smith-Waterman score: 4046; 87.8% identity (87.8% similar) in 696 aa overlap (1-611:1-696)

               10        20        30        40        50        60
pF1KSD MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
              430       440       450       460       470       480

              490       500       510       520       530          
pF1KSD DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_006 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEDTDSEE
              490       500       510       520       530       540

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 QTLPFPVPSERLPLRRMSPFSSTLNLQPSFPGRSYFDFRSSPHQLSLHSSLQSLNAPGCN
              550       560       570       580       590       600

                             540       550       560       570     
pF1KSD -------------------VAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFS
                          :::::::::::::::::::::::::::::::::::::::::
XP_006 FETQSAPYSQLVDIKKLLAVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFS
              610       620       630       640       650       660

         580       590       600       610       620       630     
pF1KSD KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTN
       ::::::::::::::::::::::::::::::::::::                        
XP_006 KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTN
              670       680       690       700       710       720

         640       650       660                                   
pF1KSD RTEGGITKGATIGVLLDFNRKNLTFFYQR                               
                                                                   
XP_006 RTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHT
              730       740       750       760       770       780

>--
 initn: 340 init1: 340 opt: 340  Z-score: 260.3  bits: 58.8 E(85289): 9.2e-08
Smith-Waterman score: 340; 98.0% identity (100.0% similar) in 50 aa overlap (612-661:697-746)

             590       600       610       620       630       640 
pF1KSD ELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGI
                                     ::::::::::::::::::::::::::::::
XP_006 ELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGI
        670       680       690       700       710       720      

             650       660                                         
pF1KSD TKGATIGVLLDFNRKNLTFFYQR                                     
       :::::::::::.::::::::                                        
XP_006 TKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPD
        730       740       750       760       770       780      




664 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:06:14 2016 done: Thu Nov  3 01:06:16 2016
 Total Scan time: 10.900 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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