FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0286, 444 aa 1>>>pF1KSDA0286 444 - 444 aa - 444 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4305+/-0.000811; mu= 17.2222+/- 0.049 mean_var=70.3243+/-14.066, 0's: 0 Z-trim(107.8): 15 B-trim: 0 in 0/49 Lambda= 0.152940 statistics sampled from 9815 (9820) to 9815 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.302), width: 16 Scan time: 2.780 The best scores are: opt bits E(32554) CCDS44927.1 NEMP1 gene_id:23306|Hs108|chr12 ( 444) 2964 663.0 1.6e-190 CCDS31841.1 NEMP1 gene_id:23306|Hs108|chr12 ( 371) 1764 398.2 7.1e-111 CCDS46476.1 NEMP2 gene_id:100131211|Hs108|chr2 ( 417) 884 204.1 2.2e-52 >>CCDS44927.1 NEMP1 gene_id:23306|Hs108|chr12 (444 aa) initn: 2964 init1: 2964 opt: 2964 Z-score: 3533.8 bits: 663.0 E(32554): 1.6e-190 Smith-Waterman score: 2964; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KSD MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY 370 380 390 400 410 420 430 440 pF1KSD EEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::: CCDS44 EEASSEEEDSYSRCPAITQNNFLT 430 440 >>CCDS31841.1 NEMP1 gene_id:23306|Hs108|chr12 (371 aa) initn: 1764 init1: 1764 opt: 1764 Z-score: 2104.0 bits: 398.2 E(32554): 7.1e-111 Smith-Waterman score: 2331; 83.6% identity (83.6% similar) in 444 aa overlap (1-444:1-371) 10 20 30 40 50 60 pF1KSD MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQ----------- 70 80 90 100 130 140 150 160 170 180 pF1KSD KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL CCDS31 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KSD SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 --SQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ 110 120 130 140 150 160 250 260 270 280 290 300 pF1KSD EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH 170 180 190 200 210 220 310 320 330 340 350 360 pF1KSD IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY 290 300 310 320 330 340 430 440 pF1KSD EEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::: CCDS31 EEASSEEEDSYSRCPAITQNNFLT 350 360 370 >>CCDS46476.1 NEMP2 gene_id:100131211|Hs108|chr2 (417 aa) initn: 894 init1: 480 opt: 884 Z-score: 1053.9 bits: 204.1 E(32554): 2.2e-52 Smith-Waterman score: 884; 34.9% identity (72.4% similar) in 381 aa overlap (52-425:39-417) 30 40 50 60 70 80 pF1KSD VGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWT :.:... . :. .::.. .:. ::. CCDS46 WLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWS 10 20 30 40 50 60 90 100 110 120 130 pF1KSD RIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSS-----FLKEKLNDTYVNVGLYST .:....: : :.. . .... . : .: .:.. .. .. :. . .. : CCDS46 TMQVKITSPGLFRIVYIAERHNCQYPE--NILSFIKCVIHNFWIPKESNEITIIINPYRE 70 80 90 100 110 120 140 150 160 170 180 190 pF1KSD KTCLKVEIIEKDTKYSVIVIRRF-DPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVG .:..:: ..: .: . : : . : ::::::. :..::: . ::.: ::::.: ..: CCDS46 TVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLG 130 140 150 160 170 180 200 210 220 230 240 250 pF1KSD IVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVL .. .:.........:.:: : .....:: : :.:.. ....:. .: :.:.::: CCDS46 VLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVL 190 200 210 220 230 240 260 270 280 290 300 310 pF1KSD TVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNL :::.::.::::.::: ..:: .:: : :.:..: ..:.:. .:..: : ::. . . .: CCDS46 IVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSSWSL 250 260 270 280 290 300 320 330 340 350 360 370 pF1KSD EHPIQWLYITCRKVCKG-AEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAW ..:.. :. . . : . . :::.::: :...:: .::::::. : .:: .: CCDS46 HYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSW 310 320 330 340 350 360 380 390 400 410 420 430 pF1KSD KTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRC .:::...:..::::: :.:::.:.:.:.::..::::. . ...... ... CCDS46 LVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA 370 380 390 400 410 440 pF1KSD PAITQNNFLT 444 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:07:54 2016 done: Thu Nov 3 01:07:54 2016 Total Scan time: 2.780 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]