FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0286, 444 aa 1>>>pF1KSDA0286 444 - 444 aa - 444 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0875+/-0.000348; mu= 18.9735+/- 0.022 mean_var=67.6060+/-13.634, 0's: 0 Z-trim(114.2): 26 B-trim: 125 in 1/51 Lambda= 0.155985 statistics sampled from 23863 (23888) to 23863 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.28), width: 16 Scan time: 9.010 The best scores are: opt bits E(85289) NP_001124435 (OMIM: 616496) nuclear envelope integ ( 444) 2964 676.0 5.3e-194 XP_011536359 (OMIM: 616496) PREDICTED: nuclear env ( 452) 2680 612.1 9.3e-175 XP_016874566 (OMIM: 616496) PREDICTED: nuclear env ( 452) 2680 612.1 9.3e-175 XP_011536358 (OMIM: 616496) PREDICTED: nuclear env ( 492) 2680 612.1 9.9e-175 XP_016874567 (OMIM: 616496) PREDICTED: nuclear env ( 273) 1838 422.5 6.8e-118 XP_011536361 (OMIM: 616496) PREDICTED: nuclear env ( 273) 1838 422.5 6.8e-118 NP_056072 (OMIM: 616496) nuclear envelope integral ( 371) 1764 405.9 9e-113 XP_011536360 (OMIM: 616496) PREDICTED: nuclear env ( 419) 1764 406.0 9.9e-113 XP_016874568 (OMIM: 616496) PREDICTED: nuclear env ( 253) 1700 391.4 1.4e-108 XP_011536362 (OMIM: 616496) PREDICTED: nuclear env ( 269) 1110 258.7 1.4e-68 NP_001136117 (OMIM: 616497) nuclear envelope integ ( 417) 884 207.9 4e-53 XP_011508761 (OMIM: 616497) PREDICTED: nuclear env ( 348) 826 194.8 3e-49 XP_005246269 (OMIM: 616497) PREDICTED: nuclear env ( 348) 826 194.8 3e-49 XP_005246270 (OMIM: 616497) PREDICTED: nuclear env ( 276) 768 181.7 2.1e-45 XP_016858588 (OMIM: 616497) PREDICTED: nuclear env ( 389) 737 174.8 3.5e-43 XP_016858587 (OMIM: 616497) PREDICTED: nuclear env ( 392) 736 174.6 4.1e-43 XP_011508760 (OMIM: 616497) PREDICTED: nuclear env ( 377) 733 173.9 6.3e-43 XP_016858589 (OMIM: 616497) PREDICTED: nuclear env ( 387) 733 173.9 6.5e-43 >>NP_001124435 (OMIM: 616496) nuclear envelope integral (444 aa) initn: 2964 init1: 2964 opt: 2964 Z-score: 3604.0 bits: 676.0 E(85289): 5.3e-194 Smith-Waterman score: 2964; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KSD MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY 370 380 390 400 410 420 430 440 pF1KSD EEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::: NP_001 EEASSEEEDSYSRCPAITQNNFLT 430 440 >>XP_011536359 (OMIM: 616496) PREDICTED: nuclear envelop (452 aa) initn: 2680 init1: 2680 opt: 2680 Z-score: 3258.5 bits: 612.1 E(85289): 9.3e-175 Smith-Waterman score: 2680; 100.0% identity (100.0% similar) in 403 aa overlap (42-444:50-452) 20 30 40 50 60 70 pF1KSD AVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNV :::::::::::::::::::::::::::::: XP_011 LRTRNFQPVAKGKRQRQRRRPWETIEKHKETAETDVNVVMLQESQVCEKRASQQFCYTNV 20 30 40 50 60 70 80 90 100 110 120 130 pF1KSD LIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNV 80 90 100 110 120 130 140 150 160 170 180 190 pF1KSD GLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTG 140 150 160 170 180 190 200 210 220 230 240 250 pF1KSD MTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLL 200 210 220 230 240 250 260 270 280 290 300 310 pF1KSD SYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALC 260 270 280 290 300 310 320 330 340 350 360 370 pF1KSD TKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDC 320 330 340 350 360 370 380 390 400 410 420 430 pF1KSD SAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSY 380 390 400 410 420 430 440 pF1KSD SRCPAITQNNFLT ::::::::::::: XP_011 SRCPAITQNNFLT 440 450 >>XP_016874566 (OMIM: 616496) PREDICTED: nuclear envelop (452 aa) initn: 2680 init1: 2680 opt: 2680 Z-score: 3258.5 bits: 612.1 E(85289): 9.3e-175 Smith-Waterman score: 2680; 100.0% identity (100.0% similar) in 403 aa overlap (42-444:50-452) 20 30 40 50 60 70 pF1KSD AVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNV :::::::::::::::::::::::::::::: XP_016 LRTRNFQPVAKGKRQRQRRRPWETIEKHKETAETDVNVVMLQESQVCEKRASQQFCYTNV 20 30 40 50 60 70 80 90 100 110 120 130 pF1KSD LIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNV 80 90 100 110 120 130 140 150 160 170 180 190 pF1KSD GLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTG 140 150 160 170 180 190 200 210 220 230 240 250 pF1KSD MTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLL 200 210 220 230 240 250 260 270 280 290 300 310 pF1KSD SYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALC 260 270 280 290 300 310 320 330 340 350 360 370 pF1KSD TKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDC 320 330 340 350 360 370 380 390 400 410 420 430 pF1KSD SAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSY 380 390 400 410 420 430 440 pF1KSD SRCPAITQNNFLT ::::::::::::: XP_016 SRCPAITQNNFLT 440 450 >>XP_011536358 (OMIM: 616496) PREDICTED: nuclear envelop (492 aa) initn: 2680 init1: 2680 opt: 2680 Z-score: 3257.9 bits: 612.1 E(85289): 9.9e-175 Smith-Waterman score: 2687; 92.2% identity (93.9% similar) in 446 aa overlap (2-444:61-492) 10 20 pF1KSD MAGGMK---VAVSPAVGPGPWGSGVGGGGTV ::... . .: : :: : ..: XP_011 NPPPSPPLVSPSPIWFALHSRPRLGGLLGEAGALRARPIDSKPQGKEGGWGPGKASG--- 40 50 60 70 80 30 40 50 60 70 80 pF1KSD RLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN .::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----------LATAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN 90 100 110 120 130 90 100 110 120 130 140 pF1KSD SSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKD 140 150 160 170 180 190 150 160 170 180 190 200 pF1KSD TKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILS 200 210 220 230 240 250 210 220 230 240 250 260 pF1KSD KFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKY 260 270 280 290 300 310 270 280 290 300 310 320 pF1KSD GPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRK 320 330 340 350 360 370 330 340 350 360 370 380 pF1KSD VCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFAD 380 390 400 410 420 430 390 400 410 420 430 440 pF1KSD FVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT 440 450 460 470 480 490 >>XP_016874567 (OMIM: 616496) PREDICTED: nuclear envelop (273 aa) initn: 1838 init1: 1838 opt: 1838 Z-score: 2237.5 bits: 422.5 E(85289): 6.8e-118 Smith-Waterman score: 1838; 100.0% identity (100.0% similar) in 273 aa overlap (172-444:1-273) 150 160 170 180 190 200 pF1KSD VEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLL :::::::::::::::::::::::::::::: XP_016 MLFFCGDLLSRSQIFYYSTGMTVGIVASLL 10 20 30 210 220 230 240 250 260 pF1KSD IIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMS 40 50 60 70 80 90 270 280 290 300 310 320 pF1KSD FAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQW 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD LYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQ 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD SPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNN 220 230 240 250 260 270 pF1KSD FLT ::: XP_016 FLT >>XP_011536361 (OMIM: 616496) PREDICTED: nuclear envelop (273 aa) initn: 1838 init1: 1838 opt: 1838 Z-score: 2237.5 bits: 422.5 E(85289): 6.8e-118 Smith-Waterman score: 1838; 100.0% identity (100.0% similar) in 273 aa overlap (172-444:1-273) 150 160 170 180 190 200 pF1KSD VEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLL :::::::::::::::::::::::::::::: XP_011 MLFFCGDLLSRSQIFYYSTGMTVGIVASLL 10 20 30 210 220 230 240 250 260 pF1KSD IIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMS 40 50 60 70 80 90 270 280 290 300 310 320 pF1KSD FAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQW 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD LYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQ 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD SPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNN 220 230 240 250 260 270 pF1KSD FLT ::: XP_011 FLT >>NP_056072 (OMIM: 616496) nuclear envelope integral mem (371 aa) initn: 1764 init1: 1764 opt: 1764 Z-score: 2145.6 bits: 405.9 E(85289): 9e-113 Smith-Waterman score: 2331; 83.6% identity (83.6% similar) in 444 aa overlap (1-444:1-371) 10 20 30 40 50 60 pF1KSD MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQ----------- 70 80 90 100 130 140 150 160 170 180 pF1KSD KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL NP_056 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KSD SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 --SQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ 110 120 130 140 150 160 250 260 270 280 290 300 pF1KSD EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH 170 180 190 200 210 220 310 320 330 340 350 360 pF1KSD IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY 290 300 310 320 330 340 430 440 pF1KSD EEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::: NP_056 EEASSEEEDSYSRCPAITQNNFLT 350 360 370 >>XP_011536360 (OMIM: 616496) PREDICTED: nuclear envelop (419 aa) initn: 1764 init1: 1764 opt: 1764 Z-score: 2144.9 bits: 406.0 E(85289): 9.9e-113 Smith-Waterman score: 2054; 75.8% identity (77.6% similar) in 446 aa overlap (2-444:61-419) 10 20 pF1KSD MAGGMK---VAVSPAVGPGPWGSGVGGGGTV ::... . .: : :: : ..: XP_011 NPPPSPPLVSPSPIWFALHSRPRLGGLLGEAGALRARPIDSKPQGKEGGWGPGKASG--- 40 50 60 70 80 30 40 50 60 70 80 pF1KSD RLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN .::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----------LATAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN 90 100 110 120 130 90 100 110 120 130 140 pF1KSD SSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKD ::::::::::::::::::::: XP_011 SSRLVRVTQVENEEKLKELEQ--------------------------------------- 140 150 150 160 170 180 190 200 pF1KSD TKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILS :::::::::::::::::::::::::: XP_011 ----------------------------------SQIFYYSTGMTVGIVASLLIIIFILS 160 170 180 210 220 230 240 250 260 pF1KSD KFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKY 190 200 210 220 230 240 270 280 290 300 310 320 pF1KSD GPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRK 250 260 270 280 290 300 330 340 350 360 370 380 pF1KSD VCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFAD 310 320 330 340 350 360 390 400 410 420 430 440 pF1KSD FVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT 370 380 390 400 410 >>XP_016874568 (OMIM: 616496) PREDICTED: nuclear envelop (253 aa) initn: 1700 init1: 1700 opt: 1700 Z-score: 2070.2 bits: 391.4 E(85289): 1.4e-108 Smith-Waterman score: 1700; 100.0% identity (100.0% similar) in 253 aa overlap (192-444:1-253) 170 180 190 200 210 220 pF1KSD KLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVIL :::::::::::::::::::::::::::::: XP_016 MTVGIVASLLIIIFILSKFMPKKSPIYVIL 10 20 30 230 240 250 260 270 280 pF1KSD VGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLT 40 50 60 70 80 90 290 300 310 320 330 340 pF1KSD WTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRL 100 110 120 130 140 150 350 360 370 380 390 400 pF1KSD LTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEV 160 170 180 190 200 210 410 420 430 440 pF1KSD SVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT ::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT 220 230 240 250 >>XP_011536362 (OMIM: 616496) PREDICTED: nuclear envelop (269 aa) initn: 1110 init1: 1110 opt: 1110 Z-score: 1352.2 bits: 258.7 E(85289): 1.4e-68 Smith-Waterman score: 1117; 83.7% identity (87.4% similar) in 215 aa overlap (2-213:61-261) 10 20 pF1KSD MAGGMK---VAVSPAVGPGPWGSGVGGGGTV ::... . .: : :: : ..: XP_011 NPPPSPPLVSPSPIWFALHSRPRLGGLLGEAGALRARPIDSKPQGKEGGWGPGKASG--- 40 50 60 70 80 30 40 50 60 70 80 pF1KSD RLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN .::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----------LATAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVN 90 100 110 120 130 90 100 110 120 130 140 pF1KSD SSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKD 140 150 160 170 180 190 150 160 170 180 190 200 pF1KSD TKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILS 200 210 220 230 240 250 210 220 230 240 250 260 pF1KSD KFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKY ::::: XP_011 KFMPKVMSSQLDS 260 444 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:07:55 2016 done: Thu Nov 3 01:07:56 2016 Total Scan time: 9.010 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]