FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0313, 1499 aa 1>>>pF1KSDA0313 1499 - 1499 aa - 1499 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8740+/-0.000463; mu= -2.7263+/- 0.029 mean_var=274.1095+/-56.179, 0's: 0 Z-trim(118.3): 208 B-trim: 508 in 1/54 Lambda= 0.077466 statistics sampled from 30866 (31085) to 30866 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.364), width: 16 Scan time: 14.340 The best scores are: opt bits E(85289) NP_055062 (OMIM: 609530) rap guanine nucleotide ex (1499) 9857 1116.4 0 XP_016864347 (OMIM: 609530) PREDICTED: rap guanine (1544) 9731 1102.4 0 XP_016864346 (OMIM: 609530) PREDICTED: rap guanine (1544) 9731 1102.4 0 XP_005263417 (OMIM: 609530) PREDICTED: rap guanine (1660) 9731 1102.4 0 XP_005263418 (OMIM: 609530) PREDICTED: rap guanine (1654) 9730 1102.3 0 XP_016864345 (OMIM: 609530) PREDICTED: rap guanine (1652) 9647 1093.0 0 XP_016864348 (OMIM: 609530) PREDICTED: rap guanine (1524) 7386 840.3 0 XP_011530729 (OMIM: 609530) PREDICTED: rap guanine (1540) 7380 839.6 0 XP_006714484 (OMIM: 609530) PREDICTED: rap guanine (1685) 7260 826.2 0 XP_011530728 (OMIM: 609530) PREDICTED: rap guanine (1585) 7254 825.5 0 XP_006714485 (OMIM: 609530) PREDICTED: rap guanine (1585) 7254 825.5 0 XP_011530727 (OMIM: 609530) PREDICTED: rap guanine (1589) 7254 825.5 0 XP_005263415 (OMIM: 609530) PREDICTED: rap guanine (1701) 7254 825.5 0 XP_006714483 (OMIM: 609530) PREDICTED: rap guanine (1695) 7253 825.4 0 XP_005263416 (OMIM: 609530) PREDICTED: rap guanine (1693) 7164 815.5 0 NP_001157859 (OMIM: 610499) rap guanine nucleotide (1509) 5188 594.6 1.9e-168 NP_001157860 (OMIM: 610499) rap guanine nucleotide (1504) 5084 583.0 6.1e-165 NP_001157858 (OMIM: 610499) rap guanine nucleotide (1609) 5084 583.0 6.4e-165 NP_057424 (OMIM: 610499) rap guanine nucleotide ex (1601) 4629 532.2 1.3e-149 NP_001157861 (OMIM: 610499) rap guanine nucleotide (1391) 4625 531.7 1.6e-149 NP_001157862 (OMIM: 610499) rap guanine nucleotide ( 827) 3242 377.0 3.4e-103 NP_001269830 (OMIM: 606058) rap guanine nucleotide ( 791) 594 81.0 4.1e-14 NP_001269829 (OMIM: 606058) rap guanine nucleotide ( 840) 594 81.1 4.3e-14 XP_006712268 (OMIM: 606058) PREDICTED: rap guanine ( 840) 594 81.1 4.3e-14 XP_016858686 (OMIM: 606058) PREDICTED: rap guanine ( 849) 594 81.1 4.3e-14 NP_001269828 (OMIM: 606058) rap guanine nucleotide ( 858) 594 81.1 4.3e-14 NP_001093867 (OMIM: 606058) rap guanine nucleotide ( 867) 594 81.1 4.4e-14 XP_011508807 (OMIM: 606058) PREDICTED: rap guanine ( 881) 594 81.1 4.4e-14 XP_005246303 (OMIM: 606058) PREDICTED: rap guanine ( 993) 594 81.1 4.9e-14 NP_008954 (OMIM: 606058) rap guanine nucleotide ex (1011) 594 81.1 5e-14 XP_011513954 (OMIM: 609527) PREDICTED: rap guanine ( 554) 576 79.0 1.2e-13 NP_036426 (OMIM: 609527) rap guanine nucleotide ex ( 730) 576 79.0 1.5e-13 XP_005249973 (OMIM: 609527) PREDICTED: rap guanine ( 730) 576 79.0 1.5e-13 XP_016868326 (OMIM: 609527) PREDICTED: rap guanine ( 758) 576 79.0 1.6e-13 XP_005249971 (OMIM: 609527) PREDICTED: rap guanine ( 883) 576 79.1 1.8e-13 XP_016858685 (OMIM: 606058) PREDICTED: rap guanine ( 960) 556 76.8 9.1e-13 XP_005268628 (OMIM: 606057) PREDICTED: rap guanine ( 495) 532 74.0 3.3e-12 XP_011536060 (OMIM: 606057) PREDICTED: rap guanine ( 779) 532 74.1 4.9e-12 NP_001092002 (OMIM: 606057) rap guanine nucleotide ( 881) 532 74.1 5.4e-12 NP_006096 (OMIM: 606057) rap guanine nucleotide ex ( 881) 532 74.1 5.4e-12 XP_011536057 (OMIM: 606057) PREDICTED: rap guanine ( 896) 532 74.1 5.5e-12 NP_001092001 (OMIM: 606057) rap guanine nucleotide ( 923) 532 74.2 5.6e-12 XP_011536054 (OMIM: 606057) PREDICTED: rap guanine ( 938) 532 74.2 5.7e-12 NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077) 355 54.4 5.8e-06 NP_001287665 (OMIM: 614532) ras-GEF domain-contain ( 431) 345 53.1 5.8e-06 XP_016863301 (OMIM: 614532) PREDICTED: ras-GEF dom ( 432) 345 53.1 5.8e-06 NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094) 355 54.4 5.8e-06 NP_941372 (OMIM: 600303) rap guanine nucleotide ex (1095) 355 54.4 5.8e-06 XP_006717137 (OMIM: 600303) PREDICTED: rap guanine (1100) 355 54.4 5.9e-06 XP_011516881 (OMIM: 600303) PREDICTED: rap guanine (1108) 355 54.4 5.9e-06 >>NP_055062 (OMIM: 609530) rap guanine nucleotide exchan (1499 aa) initn: 9857 init1: 9857 opt: 9857 Z-score: 5965.1 bits: 1116.4 E(85289): 0 Smith-Waterman score: 9857; 100.0% identity (100.0% similar) in 1499 aa overlap (1-1499:1-1499) 10 20 30 40 50 60 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGYTLAPSGTVDNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGYTLAPSGTVDNF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD SDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQY 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD QSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD ASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVAR 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KSD SSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV 1450 1460 1470 1480 1490 >>XP_016864347 (OMIM: 609530) PREDICTED: rap guanine nuc (1544 aa) initn: 9723 init1: 9723 opt: 9731 Z-score: 5888.8 bits: 1102.4 E(85289): 0 Smith-Waterman score: 9731; 99.3% identity (99.5% similar) in 1493 aa overlap (7-1499:52-1544) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_016 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 510 520 530 540 550 560 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 630 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 690 700 710 720 730 740 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 750 760 770 780 790 800 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 870 880 890 900 910 920 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ 930 940 950 960 970 980 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1110 1120 1130 1140 1150 1160 1120 1130 1140 1150 1160 1170 pF1KSD PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS 1170 1180 1190 1200 1210 1220 1180 1190 1200 1210 1220 1230 pF1KSD VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR 1230 1240 1250 1260 1270 1280 1240 1250 1260 1270 1280 1290 pF1KSD ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD 1290 1300 1310 1320 1330 1340 1300 1310 1320 1330 1340 1350 pF1KSD QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA 1350 1360 1370 1380 1390 1400 1360 1370 1380 1390 1400 1410 pF1KSD ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE 1410 1420 1430 1440 1450 1460 1420 1430 1440 1450 1460 1470 pF1KSD GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP 1470 1480 1490 1500 1510 1520 1480 1490 pF1KSD RLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::: XP_016 RLAPYQSQGFSTEEDEDEQVSAV 1530 1540 >>XP_016864346 (OMIM: 609530) PREDICTED: rap guanine nuc (1544 aa) initn: 9723 init1: 9723 opt: 9731 Z-score: 5888.8 bits: 1102.4 E(85289): 0 Smith-Waterman score: 9731; 99.3% identity (99.5% similar) in 1493 aa overlap (7-1499:52-1544) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_016 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 510 520 530 540 550 560 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 630 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 690 700 710 720 730 740 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 750 760 770 780 790 800 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 870 880 890 900 910 920 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ 930 940 950 960 970 980 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1110 1120 1130 1140 1150 1160 1120 1130 1140 1150 1160 1170 pF1KSD PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS 1170 1180 1190 1200 1210 1220 1180 1190 1200 1210 1220 1230 pF1KSD VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR 1230 1240 1250 1260 1270 1280 1240 1250 1260 1270 1280 1290 pF1KSD ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD 1290 1300 1310 1320 1330 1340 1300 1310 1320 1330 1340 1350 pF1KSD QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA 1350 1360 1370 1380 1390 1400 1360 1370 1380 1390 1400 1410 pF1KSD ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE 1410 1420 1430 1440 1450 1460 1420 1430 1440 1450 1460 1470 pF1KSD GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP 1470 1480 1490 1500 1510 1520 1480 1490 pF1KSD RLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::: XP_016 RLAPYQSQGFSTEEDEDEQVSAV 1530 1540 >>XP_005263417 (OMIM: 609530) PREDICTED: rap guanine nuc (1660 aa) initn: 9723 init1: 9723 opt: 9731 Z-score: 5888.4 bits: 1102.4 E(85289): 0 Smith-Waterman score: 9731; 99.3% identity (99.5% similar) in 1493 aa overlap (7-1499:168-1660) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_005 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 140 150 160 170 180 190 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 200 210 220 230 240 250 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 260 270 280 290 300 310 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 320 330 340 350 360 370 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 380 390 400 410 420 430 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 440 450 460 470 480 490 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 500 510 520 530 540 550 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 560 570 580 590 600 610 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 620 630 640 650 660 670 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 680 690 700 710 720 730 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 740 750 760 770 780 790 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 800 810 820 830 840 850 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 860 870 880 890 900 910 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 920 930 940 950 960 970 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 980 990 1000 1010 1020 1030 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1220 1230 1240 1250 1260 1270 1120 1130 1140 1150 1160 1170 pF1KSD PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS 1280 1290 1300 1310 1320 1330 1180 1190 1200 1210 1220 1230 pF1KSD VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR 1340 1350 1360 1370 1380 1390 1240 1250 1260 1270 1280 1290 pF1KSD ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD 1400 1410 1420 1430 1440 1450 1300 1310 1320 1330 1340 1350 pF1KSD QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA 1460 1470 1480 1490 1500 1510 1360 1370 1380 1390 1400 1410 pF1KSD ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE 1520 1530 1540 1550 1560 1570 1420 1430 1440 1450 1460 1470 pF1KSD GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP 1580 1590 1600 1610 1620 1630 1480 1490 pF1KSD RLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::: XP_005 RLAPYQSQGFSTEEDEDEQVSAV 1640 1650 1660 >>XP_005263418 (OMIM: 609530) PREDICTED: rap guanine nuc (1654 aa) initn: 9730 init1: 9730 opt: 9730 Z-score: 5887.8 bits: 1102.3 E(85289): 0 Smith-Waterman score: 9730; 99.9% identity (100.0% similar) in 1481 aa overlap (19-1499:174-1654) 10 20 30 40 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGC :.:::::::::::::::::::::::::::: XP_005 RKINQKGERQTIIDTVDPYPMGKPPLPRGYHTLPADFTKLHLTDSLHPQVTHVSSSHSGC 150 160 170 180 190 200 50 60 70 80 90 100 pF1KSD SITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVR 210 220 230 240 250 260 110 120 130 140 150 160 pF1KSD DCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGE 270 280 290 300 310 320 170 180 190 200 210 220 pF1KSD ELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQ 330 340 350 360 370 380 230 240 250 260 270 280 pF1KSD QDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHS 390 400 410 420 430 440 290 300 310 320 330 340 pF1KSD VVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDP 450 460 470 480 490 500 350 360 370 380 390 400 pF1KSD AMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKG 510 520 530 540 550 560 410 420 430 440 450 460 pF1KSD FGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLF 570 580 590 600 610 620 470 480 490 500 510 520 pF1KSD VFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVG 630 640 650 660 670 680 530 540 550 560 570 580 pF1KSD GRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPD 690 700 710 720 730 740 590 600 610 620 630 640 pF1KSD LLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPD 750 760 770 780 790 800 650 660 670 680 690 700 pF1KSD QYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRE 810 820 830 840 850 860 710 720 730 740 750 760 pF1KSD SQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQET 870 880 890 900 910 920 770 780 790 800 810 820 pF1KSD FWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEK 930 940 950 960 970 980 830 840 850 860 870 880 pF1KSD LPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKV 990 1000 1010 1020 1030 1040 890 900 910 920 930 940 pF1KSD DGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQ 1050 1060 1070 1080 1090 1100 950 960 970 980 990 1000 pF1KSD TGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLP 1110 1120 1130 1140 1150 1160 1010 1020 1030 1040 1050 1060 pF1KSD KNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKV 1170 1180 1190 1200 1210 1220 1070 1080 1090 1100 1110 1120 pF1KSD PVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKG 1230 1240 1250 1260 1270 1280 1130 1140 1150 1160 1170 1180 pF1KSD YTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGR 1290 1300 1310 1320 1330 1340 1190 1200 1210 1220 1230 1240 pF1KSD MERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGS 1350 1360 1370 1380 1390 1400 1250 1260 1270 1280 1290 1300 pF1KSD WTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYN 1410 1420 1430 1440 1450 1460 1310 1320 1330 1340 1350 1360 pF1KSD RQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEE 1470 1480 1490 1500 1510 1520 1370 1380 1390 1400 1410 1420 pF1KSD TKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDY 1530 1540 1550 1560 1570 1580 1430 1440 1450 1460 1470 1480 pF1KSD NVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFST 1590 1600 1610 1620 1630 1640 1490 pF1KSD EEDEDEQVSAV ::::::::::: XP_005 EEDEDEQVSAV 1650 >>XP_016864345 (OMIM: 609530) PREDICTED: rap guanine nuc (1652 aa) initn: 9651 init1: 5891 opt: 9647 Z-score: 5837.7 bits: 1093.0 E(85289): 0 Smith-Waterman score: 9647; 98.7% identity (98.9% similar) in 1493 aa overlap (7-1499:168-1652) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_016 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 140 150 160 170 180 190 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 200 210 220 230 240 250 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 260 270 280 290 300 310 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 320 330 340 350 360 370 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 380 390 400 410 420 430 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 440 450 460 470 480 490 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 500 510 520 530 540 550 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 560 570 580 590 600 610 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 620 630 640 650 660 670 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 680 690 700 710 720 730 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 740 750 760 770 780 790 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 800 810 820 830 840 850 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 860 870 880 890 900 910 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 920 930 940 950 960 970 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 980 990 1000 1010 1020 1030 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::: :::: XP_016 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTR--------SLSQ 1040 1050 1060 1070 1080 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 1090 1100 1110 1120 1130 1140 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1150 1160 1170 1180 1190 1200 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1210 1220 1230 1240 1250 1260 1120 1130 1140 1150 1160 1170 pF1KSD PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHS 1270 1280 1290 1300 1310 1320 1180 1190 1200 1210 1220 1230 pF1KSD VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDR 1330 1340 1350 1360 1370 1380 1240 1250 1260 1270 1280 1290 pF1KSD ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMD 1390 1400 1410 1420 1430 1440 1300 1310 1320 1330 1340 1350 pF1KSD QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEA 1450 1460 1470 1480 1490 1500 1360 1370 1380 1390 1400 1410 pF1KSD ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPE 1510 1520 1530 1540 1550 1560 1420 1430 1440 1450 1460 1470 pF1KSD GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDP 1570 1580 1590 1600 1610 1620 1480 1490 pF1KSD RLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::: XP_016 RLAPYQSQGFSTEEDEDEQVSAV 1630 1640 1650 >>XP_016864348 (OMIM: 609530) PREDICTED: rap guanine nuc (1524 aa) initn: 7356 init1: 7356 opt: 7386 Z-score: 4472.5 bits: 840.3 E(85289): 0 Smith-Waterman score: 9797; 98.4% identity (98.4% similar) in 1524 aa overlap (1-1499:1-1524) 10 20 30 40 50 60 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKG------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGGSGNQLRSFGSG 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 pF1KSD -------------YTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRH ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLDLTSSSSSLGSYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRH 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD SVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGD 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD RASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHM 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KSD DQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIE 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KSD AESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFP 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD EGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESD 1450 1460 1470 1480 1490 1500 1480 1490 pF1KSD PRLAPYQSQGFSTEEDEDEQVSAV :::::::::::::::::::::::: XP_016 PRLAPYQSQGFSTEEDEDEQVSAV 1510 1520 >>XP_011530729 (OMIM: 609530) PREDICTED: rap guanine nuc (1540 aa) initn: 7356 init1: 7356 opt: 7380 Z-score: 4468.8 bits: 839.6 E(85289): 0 Smith-Waterman score: 9710; 97.3% identity (97.3% similar) in 1531 aa overlap (1-1490:1-1531) 10 20 30 40 50 60 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKG------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGGSGNQLRSFGSG 1090 1100 1110 1120 1130 1140 1130 1140 1150 pF1KSD -----------------------------YTLAPSGTVDNFSDSGHSEISSRSSIVSNSS ::::::::::::::::::::::::::::::: XP_011 QLDLTSSSSSLGSENSNKNNNAPRTYGIGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSS 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KSD FDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATAT 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KSD VISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHF 1270 1280 1290 1300 1310 1320 1280 1290 1300 1310 1320 1330 pF1KSD DYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEG 1330 1340 1350 1360 1370 1380 1340 1350 1360 1370 1380 1390 pF1KSD DTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREP 1390 1400 1410 1420 1430 1440 1400 1410 1420 1430 1440 1450 pF1KSD PPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTS 1450 1460 1470 1480 1490 1500 1460 1470 1480 1490 pF1KSD SRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV ::::::::::::::::::::::::::::::: XP_011 SRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV 1510 1520 1530 1540 >>XP_006714484 (OMIM: 609530) PREDICTED: rap guanine nuc (1685 aa) initn: 7222 init1: 7222 opt: 7260 Z-score: 4395.8 bits: 826.2 E(85289): 0 Smith-Waterman score: 9671; 97.6% identity (97.8% similar) in 1518 aa overlap (7-1499:168-1685) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_006 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 140 150 160 170 180 190 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 200 210 220 230 240 250 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 260 270 280 290 300 310 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 320 330 340 350 360 370 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 380 390 400 410 420 430 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 440 450 460 470 480 490 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 500 510 520 530 540 550 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 560 570 580 590 600 610 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 620 630 640 650 660 670 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 680 690 700 710 720 730 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 740 750 760 770 780 790 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 800 810 820 830 840 850 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 860 870 880 890 900 910 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 920 930 940 950 960 970 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 980 990 1000 1010 1020 1030 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ 1040 1050 1060 1070 1080 1090 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 1100 1110 1120 1130 1140 1150 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1160 1170 1180 1190 1200 1210 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1220 1230 1240 1250 1260 1270 1120 1130 1140 1150 pF1KSD PPTSPQSSPRKG-------------------------YTLAPSGTVDNFSDSGHSEISSR :::::::::::: ::::::::::::::::::::::: XP_006 PPTSPQSSPRKGGSGNQLRSFGSGQLDLTSSSSSLGSYTLAPSGTVDNFSDSGHSEISSR 1280 1290 1300 1310 1320 1330 1160 1170 1180 1190 1200 1210 pF1KSD SSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEG 1340 1350 1360 1370 1380 1390 1220 1230 1240 1250 1260 1270 pF1KSD RGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWET 1400 1410 1420 1430 1440 1450 1280 1290 1300 1310 1320 1330 pF1KSD LPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTG 1460 1470 1480 1490 1500 1510 1340 1350 1360 1370 1380 1390 pF1KSD YWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIAR 1520 1530 1540 1550 1560 1570 1400 1410 1420 1430 1440 1450 pF1KSD KEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQ 1580 1590 1600 1610 1620 1630 1460 1470 1480 1490 pF1KSD QPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV 1640 1650 1660 1670 1680 >>XP_011530728 (OMIM: 609530) PREDICTED: rap guanine nuc (1585 aa) initn: 7222 init1: 7222 opt: 7254 Z-score: 4392.5 bits: 825.5 E(85289): 0 Smith-Waterman score: 9584; 96.6% identity (96.8% similar) in 1525 aa overlap (7-1490:52-1576) 10 20 30 pF1KSD MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHP : .: . : .:::::::::::::::: XP_011 QSRRRFRKINQKGERQTIIDTVDPYPMGKPPLPRGYHTECTKSQLPADFTKLHLTDSLHP 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIER 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRT 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTS 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLW 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAP 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNN 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLE 510 520 530 540 550 560 520 530 540 550 560 570 pF1KSD KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTAL 570 580 590 600 610 620 580 590 600 610 620 630 pF1KSD PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQ 630 640 650 660 670 680 640 650 660 670 680 690 pF1KSD AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETL 690 700 710 720 730 740 700 710 720 730 740 750 pF1KSD CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCAN 750 760 770 780 790 800 760 770 780 790 800 810 pF1KSD LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNL 810 820 830 840 850 860 820 830 840 850 860 870 pF1KSD APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKD 870 880 890 900 910 920 880 890 900 910 920 930 pF1KSD LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQ 930 940 950 960 970 980 940 950 960 970 980 990 pF1KSD GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTL 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KSD SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQV 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KSD PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSS 1110 1120 1130 1140 1150 1160 1120 1130 pF1KSD PPTSPQSSPRKG-----------------------------------------YTLAPSG :::::::::::: ::::::: XP_011 PPTSPQSSPRKGGSGNQLRSFGSGQLDLTSSSSSLGSENSNKNNNAPRTYGIGYTLAPSG 1170 1180 1190 1200 1210 1220 1140 1150 1160 1170 1180 1190 pF1KSD TVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMI 1230 1240 1250 1260 1270 1280 1200 1210 1220 1230 1240 1250 pF1KSD EPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSG 1290 1300 1310 1320 1330 1340 1260 1270 1280 1290 1300 1310 pF1KSD SHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRE 1350 1360 1370 1380 1390 1400 1320 1330 1340 1350 1360 1370 pF1KSD SLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMP 1410 1420 1430 1440 1450 1460 1380 1390 1400 1410 1420 1430 pF1KSD AHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRS 1470 1480 1490 1500 1510 1520 1440 1450 1460 1470 1480 1490 pF1KSD RMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQ 1530 1540 1550 1560 1570 1580 pF1KSD VSAV XP_011 VSAV 1499 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:12:42 2016 done: Thu Nov 3 01:12:44 2016 Total Scan time: 14.340 Total Display time: 0.980 Function used was FASTA [36.3.4 Apr, 2011]