FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0315, 1838 aa 1>>>pF1KSDA0315 1838 - 1838 aa - 1838 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6188+/-0.000419; mu= 23.8132+/- 0.026 mean_var=97.1334+/-19.628, 0's: 0 Z-trim(113.2): 173 B-trim: 16 in 1/54 Lambda= 0.130134 statistics sampled from 22174 (22367) to 22174 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.262), width: 16 Scan time: 17.920 The best scores are: opt bits E(85289) XP_016884192 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 NP_036533 (OMIM: 604293) plexin-B2 precursor [Homo (1838) 12379 2336.1 0 XP_005261968 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 XP_005261966 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 XP_006724476 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 XP_005261967 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 XP_016884193 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 12379 2336.1 0 XP_011528984 (OMIM: 604293) PREDICTED: plexin-B2 i (1901) 12379 2336.1 0 NP_055918 (OMIM: 604282) plexin-D1 precursor [Homo (1925) 1979 383.6 1e-104 XP_011510890 (OMIM: 604282) PREDICTED: plexin-D1 i (1894) 1895 367.8 5.5e-100 XP_005273222 (OMIM: 601054) PREDICTED: plexin-A2 i (1823) 1676 326.7 1.3e-87 NP_002664 (OMIM: 601053) plexin-B1 precursor [Homo (2135) 1671 325.8 2.8e-87 NP_001123554 (OMIM: 601053) plexin-B1 precursor [H (2135) 1671 325.8 2.8e-87 XP_016862120 (OMIM: 601053) PREDICTED: plexin-B1 i (2135) 1671 325.8 2.8e-87 XP_011532136 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_011532137 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_011532135 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_011532139 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_016862119 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_011532138 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 1659 323.6 1.3e-86 XP_005274762 (OMIM: 300022) PREDICTED: plexin-A3 i (1853) 1635 319.0 2.7e-85 XP_006724892 (OMIM: 300022) PREDICTED: plexin-A3 i (1841) 1430 280.5 1e-73 XP_011510891 (OMIM: 604282) PREDICTED: plexin-D1 i (1795) 1414 277.5 8.1e-73 NP_115618 (OMIM: 601055) plexin-A1 precursor [Homo (1896) 1282 252.8 2.4e-65 XP_011511210 (OMIM: 601055) PREDICTED: plexin-A1 i (1914) 1282 252.8 2.5e-65 XP_011511211 (OMIM: 601055) PREDICTED: plexin-A1 i (1914) 1282 252.8 2.5e-65 XP_011510892 (OMIM: 604282) PREDICTED: plexin-D1 i (1467) 1251 246.8 1.1e-63 XP_011529485 (OMIM: 300022) PREDICTED: plexin-A3 i (1684) 1235 243.9 1e-62 XP_005274763 (OMIM: 300022) PREDICTED: plexin-A3 i (1789) 1235 243.9 1.1e-62 NP_059984 (OMIM: 300022) plexin-A3 precursor [Homo (1871) 1235 243.9 1.1e-62 XP_011510894 (OMIM: 604282) PREDICTED: plexin-D1 i ( 981) 1130 224.0 5.9e-57 NP_079455 (OMIM: 601054) plexin-A2 precursor [Homo (1894) 1128 223.8 1.2e-56 XP_006719249 (OMIM: 604259) PREDICTED: plexin-C1 i (1555) 1126 223.4 1.4e-56 NP_005752 (OMIM: 604259) plexin-C1 precursor [Homo (1568) 1126 223.4 1.4e-56 XP_016868268 (OMIM: 604280) PREDICTED: plexin-A4 i (1827) 1114 221.2 7.4e-56 XP_005250743 (OMIM: 604280) PREDICTED: plexin-A4 i (1894) 1114 221.2 7.6e-56 NP_065962 (OMIM: 604280) plexin-A4 isoform 1 precu (1894) 1114 221.2 7.6e-56 XP_006716234 (OMIM: 604280) PREDICTED: plexin-A4 i (1894) 1114 221.2 7.6e-56 NP_005384 (OMIM: 300214) plexin-B3 isoform 1 precu (1909) 1005 200.7 1.1e-49 NP_001156729 (OMIM: 300214) plexin-B3 isoform 2 [H (1932) 1005 200.8 1.1e-49 XP_011514978 (OMIM: 604280) PREDICTED: plexin-A4 i (1437) 991 198.0 5.6e-49 XP_005273221 (OMIM: 601054) PREDICTED: plexin-A2 i (1974) 807 163.6 1.8e-38 XP_016874161 (OMIM: 604259) PREDICTED: plexin-C1 i (1315) 663 136.4 1.8e-30 XP_011536032 (OMIM: 604259) PREDICTED: plexin-C1 i (1322) 641 132.3 3.2e-29 XP_016874160 (OMIM: 604259) PREDICTED: plexin-C1 i (1323) 641 132.3 3.2e-29 NP_001311330 (OMIM: 114550,164860,605074,607278,61 ( 934) 378 82.8 1.8e-14 NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 378 82.8 1.8e-14 XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 378 82.8 1.8e-14 NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 378 82.9 2.4e-14 XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 378 82.9 2.4e-14 >>XP_016884192 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_016 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>NP_036533 (OMIM: 604293) plexin-B2 precursor [Homo sap (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: NP_036 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_005261968 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_005 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_005261966 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_005 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_006724476 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_006 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_005261967 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_005 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_016884193 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1838 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.8 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:1-1838) 10 20 30 40 50 60 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK 1750 1760 1770 1780 1790 1800 1810 1820 1830 pF1KSD YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :::::::::::::::::::::::::::::::::::::: XP_016 YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1810 1820 1830 >>XP_011528984 (OMIM: 604293) PREDICTED: plexin-B2 isofo (1901 aa) initn: 12379 init1: 12379 opt: 12379 Z-score: 12553.6 bits: 2336.1 E(85289): 0 Smith-Waterman score: 12379; 100.0% identity (100.0% similar) in 1838 aa overlap (1-1838:64-1901) 10 20 30 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRS :::::::::::::::::::::::::::::: XP_011 EARRHRESRCWPGAETELDHWSLGEGVRGAMALQLWALTLLGLLGAGASLRPRKLDFFRS 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD EKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEA 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEG 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD VATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGY 220 230 240 250 260 270 220 230 240 250 260 270 pF1KSD LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARNRTLLARMCREDPNYYSYLEMDLQCRDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARNRTLLARMCREDPNYYSYLEMDLQCRDPD 280 290 300 310 320 330 280 290 300 310 320 330 pF1KSD IHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNAC 340 350 360 370 380 390 340 350 360 370 380 390 pF1KSD YTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGL 400 410 420 430 440 450 400 410 420 430 440 450 pF1KSD NLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDL 460 470 480 490 500 510 460 470 480 490 500 510 pF1KSD GSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHW 520 530 540 550 560 570 520 530 540 550 560 570 pF1KSD LWSRSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWSRSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGE 580 590 600 610 620 630 580 590 600 610 620 630 pF1KSD AVICNSPSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVICNSPSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISC 640 650 660 670 680 690 640 650 660 670 680 690 pF1KSD VSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGK 700 710 720 730 740 750 700 710 720 730 740 750 pF1KSD NLDTVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSYGKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLDTVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSYGKNID 760 770 780 790 800 810 760 770 780 790 800 810 pF1KSD SKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNTTSECPPPVITRIQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNTTSECPPPVITRIQP 820 830 840 850 860 870 820 830 840 850 860 870 pF1KSD ETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIVCVIEAAETPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIVCVIEAAETPFT 880 890 900 910 920 930 880 890 900 910 920 930 pF1KSD GGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRV 940 950 960 970 980 990 940 950 960 970 980 990 pF1KSD TLNGVPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNGVPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEP 1000 1010 1020 1030 1040 1050 1000 1010 1020 1030 1040 1050 pF1KSD LRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHND 1060 1070 1080 1090 1100 1110 1060 1070 1080 1090 1100 1110 pF1KSD TKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNK 1120 1130 1140 1150 1160 1170 1120 1130 1140 1150 1160 1170 pF1KSD LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNL 1180 1190 1200 1210 1220 1230 1180 1190 1200 1210 1220 1230 pF1KSD PEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAERE 1240 1250 1260 1270 1280 1290 1240 1250 1260 1270 1280 1290 pF1KSD YEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSK 1300 1310 1320 1330 1340 1350 1300 1310 1320 1330 1340 1350 pF1KSD DGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYF 1360 1370 1380 1390 1400 1410 1360 1370 1380 1390 1400 1410 pF1KSD ASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSICLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSICLY 1420 1430 1440 1450 1460 1470 1420 1430 1440 1450 1460 1470 pF1KSD QYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQ 1480 1490 1500 1510 1520 1530 1480 1490 1500 1510 1520 1530 pF1KSD DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQILSDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQILSDLD 1540 1550 1560 1570 1580 1590 1540 1550 1560 1570 1580 1590 pF1KSD LTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLEEENRVWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLEEENRVWH 1600 1610 1620 1630 1640 1650 1600 1610 1620 1630 1640 1650 pF1KSD LVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAV 1660 1670 1680 1690 1700 1710 1660 1670 1680 1690 1700 1710 pF1KSD PPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDA 1720 1730 1740 1750 1760 1770 1720 1730 1740 1750 1760 1770 pF1KSD SLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDM 1780 1790 1800 1810 1820 1830 1780 1790 1800 1810 1820 1830 pF1KSD NTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAA 1840 1850 1860 1870 1880 1890 pF1KSD LENKVTDL :::::::: XP_011 LENKVTDL 1900 >>NP_055918 (OMIM: 604282) plexin-D1 precursor [Homo sap (1925 aa) initn: 2140 init1: 725 opt: 1979 Z-score: 2001.1 bits: 383.6 E(85289): 1e-104 Smith-Waterman score: 3335; 34.7% identity (62.6% similar) in 1931 aa overlap (28-1835:53-1918) 10 20 30 40 50 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQL : : :..:.: :.:.:::.::: :::: NP_055 FQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTNNFALDGAAGTVYLAAVNRLYQL 30 40 50 60 70 80 60 70 80 90 100 110 pF1KSD D-AKLQLEQQVATGPALDNKKC-TPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGS . :.:.:: ..:.::. :. : .: . ..: : ..::: :..: ::: . .: ::: NP_055 SGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGS 90 100 110 120 130 140 120 130 140 150 160 pF1KSD LFKGICALRALSNIS---LRLFYEDGSGEKSFV-------ASNDEGVATVGLV--SSTGP ...:.: :: .::: .:. .: : :.: ...::::: ..: NP_055 IYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGA 150 160 170 180 190 200 170 180 190 200 pF1KSD GGDRVL----FVGKGNG--PHD---------NGIIVSTRLLD-RTDSREAF----EAYTD ::.:.: ..: :.. :.. : .. : :: : : . : . : NP_055 GGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDD 210 220 230 240 250 260 210 220 230 240 pF1KSD HAT-YKAGYLSTNTQQFVAAF---EDGP-----YVFFVFNQQ----DKHPARNRTLLARM . : : . ::.:: : : :.....:.. ::. .. :.::::. NP_055 NILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKE-SQARSLLARI 270 280 290 300 310 320 250 260 270 280 290 300 pF1KSD CRE-----DPNYY--SYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSR : : . ::... ::: .:. : . :.. . . :.::: : . NP_055 CLPHGAGGDAKKLTESYIQLGLQCAG----GAGRGDLYSRLVSVFPARERLFAVFERPQG 330 340 350 360 370 310 320 330 340 350 pF1KSD SSGGPGA--GLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHA----- : .. .: .:: : . :.: ..: :.::. .. : :. . . .: : : NP_055 SPAARAAPAALCAFRFADVRAAIRAARTACF--VEPAPDVV-AVLDSVVQGTGPACERKL 380 390 400 410 420 430 360 370 380 390 400 410 pF1KSD --PGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDG . ... ::. :: .::. . :..: :.. :: :.:.::. ::.:..:::: .: NP_055 NIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGL--TSVAVASVNNYTAVFLGTVNG 440 450 460 470 480 490 420 430 440 450 460 470 pF1KSD RILKVYLTPDGTSSEYDSILVEINKRVKRDLVLS-GDLGSLYAMTQDKVFRLPVQECLSY :.::. :. . . : .. :.. . .. .: : :: ::. .. :. : : . NP_055 RLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVH 500 510 520 530 540 550 480 490 500 510 520 530 pF1KSD PTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWL-WSRSKS-CVAVTSAQPQNMS :: .: . : :::::..: ::: . .: . . : :.. : : :.: . :.... NP_055 STCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMT-VLPSEID 560 570 580 590 600 610 540 550 560 570 580 pF1KSD RRAQ--GEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGEA-----VICNS-P-SSIP : . : . . ::.:: :. : .:.. ::: : : . :: : ...: NP_055 VRQEYPGMILQISGSLPSLSGM-EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFP 620 630 640 650 660 670 590 600 610 620 630 640 pF1KSD VTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDL ::.:::: :... .: .. ... .. .::: .. .. . : ::.: .: : : NP_055 PFPPNQDHV--TVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCS 680 690 700 710 720 650 660 670 680 690 pF1KSD RYHECR------EASPNPEDGIVRAHMEDSCPQFLGPSPLV-IPMNHETDVNFQGKNLDT . : : :::::: . ..::. : :::. .: . .. : NP_055 QQHSCVSNQSRCEASPNPTS-------PQDCPRTLL-SPLAPVPTGGSQNILVPLANTAF 730 740 750 760 770 780 700 710 720 730 740 750 pF1KSD VKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSY-GKNIDSK- .:..:. . : ...: : ..:: . .. . ....:: : .:. .. .:: NP_055 FQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPE 790 800 810 820 830 840 760 770 780 790 800 pF1KSD -LHVTLYNCSFGRSDCSLCRAANP-DYRCAWCGGQSRCVYEA-LCNTTSECPPPVITRIQ . : .:::..: ::: : . . . : : : : .. : .. :: : : :. NP_055 PMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDG---CRLRGPLQPMAGTCPAPEIRAIE 850 860 870 880 890 810 820 830 840 850 860 pF1KSD PETGPLGGGIRITILGSNLGVQAGDIQR-ISVAGRNCSFQPERYSVSTRIVCVIEAAETP : .::: :: .:: : ::: . .:. . . ..: : :.::.:: .:::: : : NP_055 PLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGP 900 910 920 930 940 950 870 880 890 900 910 920 pF1KSD FTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDV ..: : :.. .: :.: .:.. : :.:: .::.:::: .::::. : .::. .: NP_055 LSGVVTVNA-SKEGKSRD--RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQV 960 970 980 990 1000 1010 930 940 950 960 970 980 pF1KSD RVTLNGVPC-KVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRA :. . :: .. . ... :. : . . . : . . .. : : .:::. : NP_055 LVN-DTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITA 1020 1030 1040 1050 1060 1070 990 1000 1010 1020 1030 1040 pF1KSD FEPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQP--MTVVGTDY . : :: .::::.:.:.:. : ..: .:.: . . : . :. .: . NP_055 ISPRRSPVSGGRTITVAGERFHMVQNVSMAV----HHIGREPTLCKVLNSTLITCPSPGA 1080 1090 1100 1110 1120 1050 1060 1070 1080 1090 1100 pF1KSD VFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVK . . .. : :. . . : ...: :. . : ..:.:.: : :. . NP_055 LSNASAPVDFF---INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFS--TAKRE 1130 1140 1150 1160 1170 1180 1110 1120 1130 1140 1150 pF1KSD KQVNK--------LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPP : ... .:: . .: .. .: .. .: : .. ... ..: : NP_055 KWIKHHPGEPLTLVIHKEQDSL--GLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGA 1190 1200 1210 1220 1230 1240 1160 1170 1180 1190 1200 1210 pF1KSD PKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSV .. .:: . .. :. . ... .. . . .:... :.. .. :.:. : NP_055 --------AVGQLP-ITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLL-LLSVVALFV 1250 1260 1270 1280 1290 1220 1230 1240 1250 1260 1270 pF1KSD YCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEA-GIPVLD .: ::..::: ..: :.: .: ..:.. .: :..:. .: : :...... ::: :. NP_055 FC--TKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLE 1300 1310 1320 1330 1340 1350 1280 1290 1300 1310 pF1KSD YKTYTDRVFF------------LPSK----DGDKDVMIT----GKLDIPEPRRPVVEQAL :: .. :.:: :::. .:..... : :. ::: :: .:... NP_055 YKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGI 1360 1370 1380 1390 1400 1410 1320 1330 1340 1350 1360 1370 pF1KSD YQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLEL ::.:::.: ::: :.:.::.:..:..: . .:::::.::::::::::.::. :...: NP_055 SLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDL 1420 1430 1440 1450 1460 1470 1380 1390 1400 1410 1420 1430 pF1KSD LEQYVVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGP .. . ::::::::::.:.:::.::.::::::.:. :....:::.. :. :::.:..:: NP_055 IDASA-AKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGS 1480 1490 1500 1510 1520 1440 1450 1460 1470 1480 1490 pF1KSD VDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIID .::. ::.::::. :: ...: : ...: : :.:.. :.... ::..::::::.. NP_055 IDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILE 1530 1540 1550 1560 1570 1580 1500 1510 1520 1530 1540 1550 pF1KSD QVYRGQPCSCWPRPDSVVLEWRPGST-AQILSDLDLTSQREGRWKRVNTLMHYNVRDGAT .. : : ::: ..: ::: .:: . :: ::: :: : :..::: ::.. .::. NP_055 AFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGAS 1590 1600 1610 1620 1630 1640 1560 1570 1580 1590 1600 1610 pF1KSD LILSKVGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTK : .: . ... .:: :.. .::: ::::. : :. : ....: : NP_055 LAMSLIDKKDNTLGRVKDLDTEKY---------FHLVLPTDELAEPKK---SHRQSHRKK 1650 1660 1670 1680 1690 1620 1630 1640 1650 1660 1670 pF1KSD AITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPP-AVKYFFDFLDEQAEKHNIQDED .. :::::::::.:::::.:.:..:...:. . :: :::::::::.:::::..:.: : NP_055 VLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPD 1700 1710 1720 1730 1740 1750 1680 1690 1700 1710 1720 1730 pF1KSD TIHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDS :.::::::::::::::::::::.:.::. . .:: ::::::.:.:::. .. .:..:: NP_055 TLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDS 1760 1770 1780 1790 1800 1810 1740 1750 1760 1770 1780 1790 pF1KSD PSNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQL :.::::::::: :.:.:. ::: :..:. .:.:.::.:::: :: . . .:: ::. .. NP_055 PTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEI 1820 1830 1840 1850 1860 1870 1800 1810 1820 1830 pF1KSD YQYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL :.:...: .:. ::: .:.:.. :: ...:..: .:... NP_055 YKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYECYSEA 1880 1890 1900 1910 1920 >>XP_011510890 (OMIM: 604282) PREDICTED: plexin-D1 isofo (1894 aa) initn: 2047 init1: 639 opt: 1895 Z-score: 1916.0 bits: 367.8 E(85289): 5.5e-100 Smith-Waterman score: 3242; 34.7% identity (62.3% similar) in 1896 aa overlap (28-1801:53-1884) 10 20 30 40 50 pF1KSD MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQL : : :..:.: :.:.:::.::: :::: XP_011 FQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTNNFALDGAAGTVYLAAVNRLYQL 30 40 50 60 70 80 60 70 80 90 100 110 pF1KSD D-AKLQLEQQVATGPALDNKKC-TPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGS . :.:.:: ..:.::. :. : .: . ..: : ..::: :..: ::: . .: ::: XP_011 SGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGS 90 100 110 120 130 140 120 130 140 150 160 pF1KSD LFKGICALRALSNIS---LRLFYEDGSGEKSFV-------ASNDEGVATVGLV--SSTGP ...:.: :: .::: .:. .: : :.: ...::::: ..: XP_011 IYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGA 150 160 170 180 190 200 170 180 190 200 pF1KSD GGDRVL----FVGKGNG--PHD---------NGIIVSTRLLD-RTDSREAF----EAYTD ::.:.: ..: :.. :.. : .. : :: : : . : . : XP_011 GGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDD 210 220 230 240 250 260 210 220 230 240 250 pF1KSD HAT-YKAGYLSTNTQQFVAAF---EDGP-----YVFFVFNQQDK---HPARNRTLLARMC . : : . ::.:: : : :.....:.. . . .. :.::::.: XP_011 NILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARIC 270 280 290 300 310 320 260 270 280 290 300 pF1KSD RE-----DPNYY--SYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRS : . ::... ::: .:. : . :.. . . :.::: : . : XP_011 LPHGAGGDAKKLTESYIQLGLQCAG----GAGRGDLYSRLVSVFPARERLFAVFERPQGS 330 340 350 360 370 310 320 330 340 350 pF1KSD SGGPGA--GLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHA------ .. .: .:: : . :.: ..: :.::.. . : :. . . .: : : XP_011 PAARAAPAALCAFRFADVRAAIRAARTACFV--EPAPDVV-AVLDSVVQGTGPACERKLN 380 390 400 410 420 430 360 370 380 390 400 410 pF1KSD -PGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGR . ... ::. :: .::. . :..: :.. : ::.:.::. ::.:..:::: .:: XP_011 IQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGR 440 450 460 470 480 490 420 430 440 450 460 470 pF1KSD ILKVYLTPDGTSSEYDSILVEINKRVKRDLVLS-GDLGSLYAMTQDKVFRLPVQECLSYP .::. :. . . : .. :.. . .. .: : :: ::. .. :. : : . XP_011 LLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHS 500 510 520 530 540 550 480 490 500 510 520 530 pF1KSD TCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWL-WSRSKS-CVAVTSAQPQNMSR :: .: . : :::::..: ::: . .: . . : :.. : : :.: . :.... XP_011 TCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMT-VLPSEIDV 560 570 580 590 600 610 540 550 560 570 580 pF1KSD RAQ--GEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGEA-----VICNS-P-SSIPV : . : . . ::.:: :. : .:.. ::: : : . :: : ...: XP_011 RQEYPGMILQISGSLPSLSGM-EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPP 620 630 640 650 660 670 590 600 610 620 630 640 pF1KSD TPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLR ::.:::: :... .: .. ... .. .::: .. .. . : ::.: .: : : . XP_011 FPPNQDHV--TVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQ 680 690 700 710 720 650 660 670 680 690 pF1KSD YHECR------EASPNPEDGIVRAHMEDSCPQFLGPSPLV-IPMNHETDVNFQGKNLDTV : : :::::: . ..::. : :::. .: . .. : XP_011 QHSCVSNQSRCEASPNPTS-------PQDCPRTLL-SPLAPVPTGGSQNILVPLANTAFF 730 740 750 760 770 780 700 710 720 730 740 750 pF1KSD KGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSY-GKNIDSK-- .:..:. . : ...: : ..:: . .. . ....:: : .:. .. .:: XP_011 QGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEP 790 800 810 820 830 840 760 770 780 790 800 810 pF1KSD LHVTLYNCSFGRSDCSLCRAANP-DYRCAWCGGQSRCVYEA-LCNTTSECPPPVITRIQP . : .:::..: ::: : . . . : : : : .. : .. :: : : :.: XP_011 MTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDG---CRLRGPLQPMAGTCPAPEIHAIEP 850 860 870 880 890 820 830 840 850 860 pF1KSD ETGPLGGGIRITILGSNLGVQAGDIQR-ISVAGRNCSFQPERYSVSTRIVCVIEAAETPF .::: :: .:: : ::: . .:. . . ..: : :.::.:: .:::: : :. XP_011 LSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPL 900 910 920 930 940 950 870 880 890 900 910 920 pF1KSD TGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVR .: : :.. .: :.: .:.. : :.:: .::.:::: .::::. : .::. .: XP_011 SGVVTVNA-SKEGKSRD--RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVL 960 970 980 990 1000 1010 930 940 950 960 970 980 pF1KSD VTLNGVPC-KVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAF :. . :: .. . ... :. : . . . : . . .. : : .:::. :. XP_011 VN-DTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAI 1020 1030 1040 1050 1060 1070 990 1000 1010 1020 1030 1040 pF1KSD EPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQP--MTVVGTDYV : :: .::::.:.:.:. : ..: .:.: . . : . :. .: . . XP_011 SPRRSPVSGGRTITVAGERFHMVQNVSMAV----HHIGREPTLCKVLNSTLITCPSPGAL 1080 1090 1100 1110 1120 1130 1050 1060 1070 1080 1090 1100 pF1KSD FHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKK . .. : :. . . : ...: :. . : ..:.:.: : :. .: XP_011 SNASAPVDFF---INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFS--TAKREK 1140 1150 1160 1170 1180 1110 1120 1130 1140 1150 pF1KSD QVNK--------LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPP ... .:: . .: .. .: .. .: : .. ... ..: : XP_011 WIKHHPGEPLTLVIHKEQDSL--GLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGA- 1190 1200 1210 1220 1230 1240 1160 1170 1180 1190 1200 1210 pF1KSD KRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVY .. .:: . .. :. . ... .. . . .:... :.. .. :.:. :. XP_011 -------AVGQLP-ITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLL-LLSVVALFVF 1250 1260 1270 1280 1290 1220 1230 1240 1250 1260 1270 pF1KSD CYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEA-GIPVLDY : ::..::: ..: :.: .: ..:.. .: :..:. .: : :...... ::: :.: XP_011 C--TKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEY 1300 1310 1320 1330 1340 1350 1280 1290 1300 1310 pF1KSD KTYTDRVFF------------LPSK----DGDKDVMIT----GKLDIPEPRRPVVEQALY : .. :.:: :::. .:..... : :. ::: :: .:... XP_011 KHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGIS 1360 1370 1380 1390 1400 1410 1320 1330 1340 1350 1360 1370 pF1KSD QFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELL ::.:::.: ::: :.:.::.:..:..: . .:::::.::::::::::.::. :...:. XP_011 LFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLI 1420 1430 1440 1450 1460 1470 1380 1390 1400 1410 1420 1430 pF1KSD EQYVVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPV . . ::::::::::.:.:::.::.::::::.:. :....:::.. :. :::.:..:: . XP_011 DASA-AKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSI 1480 1490 1500 1510 1520 1530 1440 1450 1460 1470 1480 1490 pF1KSD DAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQ ::. ::.:::.. :: ...: : ...: : :.:.. :.... ::..::::::.. XP_011 DAITGKARYTLSEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEA 1540 1550 1560 1570 1580 1590 1500 1510 1520 1530 1540 1550 pF1KSD VYRGQPCSCWPRPDSVVLEWRPGST-AQILSDLDLTSQREGRWKRVNTLMHYNVRDGATL .. : : ::: ..: ::: .:: . :: ::: :: : :..::: ::.. .::.: XP_011 FCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASL 1600 1610 1620 1630 1640 1650 1560 1570 1580 1590 1600 1610 pF1KSD ILSKVGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKA .: . ... .:: :.. .::: ::::. : :. : ....: :. XP_011 AMSLIDKKDNTLGRVKDLDTEKY---------FHLVLPTDELAEPKK---SHRQSHRKKV 1660 1670 1680 1690 1620 1630 1640 1650 1660 1670 pF1KSD ITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPP-AVKYFFDFLDEQAEKHNIQDEDT . :::::::::.:::::.:.:..:...:. . :: :::::::::.:::::..:.: :: XP_011 LPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDT 1700 1710 1720 1730 1740 1750 1680 1690 1700 1710 1720 1730 pF1KSD IHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSP .::::::::::::::::::::.:.::. . .:: ::::::.:.:::. .. .:..::: XP_011 LHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSP 1760 1770 1780 1790 1800 1810 1740 1750 1760 1770 1780 1790 pF1KSD SNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLY .::::::::: :.:.:. ::: :..:. .:.:.::.:::: :: . . .:: ::. ..: XP_011 TNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIY 1820 1830 1840 1850 1860 1870 1800 1810 1820 1830 pF1KSD QYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL .:...: XP_011 KYAKRYRPQGYRPWPG 1880 1890 1838 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:13:34 2016 done: Thu Nov 3 01:13:36 2016 Total Scan time: 17.920 Total Display time: 1.040 Function used was FASTA [36.3.4 Apr, 2011]