Result of FASTA (omim) for
pF1KSDA0353
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0353, 1565 aa
1>>>pF1KSDA0353 1565 - 1565 aa - 1565 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6909+/-0.0005; mu= 3.1197+/- 0.031
mean_var=278.6261+/-57.741, 0's: 0 Z-trim(116.2): 148 B-trim: 332 in 1/55
Lambda= 0.076836
statistics sampled from 27104 (27252) to 27104 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.32), width: 16
Scan time: 15.750
The best scores are: opt bits E(85289)
NP_663780 (OMIM: 606087) synemin isoform A [Homo s (1565) 10099 1134.9 0
XP_016877524 (OMIM: 606087) PREDICTED: synemin iso (1200) 7384 833.9 0
NP_056101 (OMIM: 606087) synemin isoform B [Homo s (1253) 7384 833.9 0
XP_006717563 (OMIM: 116300,193060) PREDICTED: vime ( 466) 488 69.1 9.8e-11
NP_003371 (OMIM: 116300,193060) vimentin [Homo sap ( 466) 488 69.1 9.8e-11
NP_001124491 (OMIM: 137780,203450) glial fibrillar ( 431) 460 66.0 8e-10
NP_002046 (OMIM: 137780,203450) glial fibrillary a ( 432) 460 66.0 8e-10
NP_001229305 (OMIM: 137780,203450) glial fibrillar ( 438) 460 66.0 8e-10
XP_016879940 (OMIM: 137780,203450) PREDICTED: glia ( 472) 460 66.0 8.5e-10
NP_006253 (OMIM: 105400,170710) peripherin [Homo s ( 470) 457 65.7 1.1e-09
XP_005269082 (OMIM: 105400,170710) PREDICTED: peri ( 471) 457 65.7 1.1e-09
XP_011528502 (OMIM: 105400,162230,616924) PREDICTE ( 924) 441 64.1 6e-09
NP_001918 (OMIM: 125660,181400,601419,602067,60476 ( 470) 428 62.5 9.9e-09
NP_116116 (OMIM: 605338) alpha-internexin [Homo sa ( 499) 426 62.3 1.2e-08
NP_006608 (OMIM: 600915) nestin [Homo sapiens] (1621) 436 63.8 1.3e-08
NP_066554 (OMIM: 105400,162230,616924) neurofilame (1020) 431 63.1 1.4e-08
NP_006149 (OMIM: 162280,607684,607734) neurofilame ( 543) 412 60.7 3.8e-08
NP_005373 (OMIM: 162250) neurofilament medium poly ( 916) 395 59.0 2.1e-07
NP_000413 (OMIM: 148069,167210,184500) keratin, ty ( 432) 336 52.2 1.1e-05
NP_002270 (OMIM: 602762) keratin, type I cuticular ( 404) 312 49.5 6.6e-05
NP_005548 (OMIM: 148067,167200,613000) keratin, ty ( 473) 309 49.3 9.3e-05
NP_004129 (OMIM: 602761) keratin, type I cuticular ( 404) 306 48.9 0.0001
NP_000517 (OMIM: 125595,131760,131800,131900,14806 ( 472) 306 48.9 0.00012
NP_001243222 (OMIM: 148060) keratin, type II cytos ( 483) 303 48.6 0.00015
NP_002264 (OMIM: 148060) keratin, type II cytoskel ( 483) 303 48.6 0.00015
NP_001243211 (OMIM: 148060) keratin, type II cytos ( 511) 303 48.6 0.00016
NP_002268 (OMIM: 601077) keratin, type I cuticular ( 416) 301 48.3 0.00016
NP_002267 (OMIM: 148020) keratin, type I cytoskele ( 400) 291 47.2 0.00033
NP_003762 (OMIM: 604540) keratin, type I cuticular ( 467) 292 47.4 0.00034
NP_002271 (OMIM: 602764) keratin, type I cuticular ( 455) 289 47.0 0.00042
XP_011523096 (OMIM: 602764) PREDICTED: keratin, ty ( 455) 289 47.0 0.00042
NP_000412 (OMIM: 113800,148080,607602,609165) kera ( 584) 287 46.9 0.00059
XP_005257400 (OMIM: 113800,148080,607602,609165) P ( 624) 287 46.9 0.00062
XP_011523095 (OMIM: 602763) PREDICTED: keratin, ty ( 412) 279 45.9 0.00084
NP_066293 (OMIM: 602763) keratin, type I cuticular ( 436) 279 45.9 0.00088
NP_003761 (OMIM: 604541) keratin, type I cuticular ( 449) 279 45.9 0.0009
NP_002266 (OMIM: 148030) keratin, type I cytoskele ( 456) 279 45.9 0.00091
NP_778238 (OMIM: 608247) keratin, type II cytoskel ( 540) 280 46.1 0.00095
NP_705694 (OMIM: 148065,615785) keratin, type I cy ( 458) 278 45.8 0.00099
NP_002265 (OMIM: 148065,615785) keratin, type I cy ( 420) 277 45.7 0.001
NP_056932 (OMIM: 616671) keratin, type II cytoskel ( 638) 281 46.3 0.001
NP_002273 (OMIM: 158000,602765) keratin, type II c ( 493) 277 45.7 0.0011
NP_002269 (OMIM: 602760) keratin, type I cuticular ( 448) 275 45.5 0.0012
NP_778223 (OMIM: 194300,608248,613981,614929) kera ( 529) 275 45.5 0.0014
XP_016874785 (OMIM: 158000,601928) PREDICTED: kera ( 486) 274 45.4 0.0014
NP_001307127 (OMIM: 158000,601928) keratin, type I ( 486) 274 45.4 0.0014
NP_000415 (OMIM: 131760,131800,131900,131960,14804 ( 590) 275 45.6 0.0015
XP_005268923 (OMIM: 158000,601928) PREDICTED: kera ( 563) 274 45.5 0.0016
NP_006762 (OMIM: 604542) keratin, type I cuticular ( 456) 270 44.9 0.0018
NP_775487 (OMIM: 611159) keratin, type II cytoskel ( 520) 271 45.1 0.0019
>>NP_663780 (OMIM: 606087) synemin isoform A [Homo sapie (1565 aa)
initn: 10099 init1: 10099 opt: 10099 Z-score: 6064.5 bits: 1134.9 E(85289): 0
Smith-Waterman score: 10099; 99.7% identity (99.9% similar) in 1565 aa overlap (1-1565:1-1565)
10 20 30 40 50 60
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCLEDEKATLTLAMADWLRDYQDLLQV
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_663 ALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENEWNLFSR
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_663 KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYISEDSTIARESYRDRRDKVA
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_663 SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD SYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAW
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GSPEPGPAESSADMDGSGRHSTFGCRQFHAEKEIIFQGPISAAGKVGDYFATEESVGTQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 GSPEPGPAESSADMDGSGRHSTFGCRQFHAEKEIIFQGPISAAGKVGDYFATEESVGTQT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD SVRQLQLGPKEGFSGQIQFTAPLSDKVELGVIGDSVHMEGLPGSSTSIRHISIGPQRHQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SVRQLQLGPKEGFSGQIQFTAPLSDKVELGVIGDSVHMEGLPGSSTSIRHISIGPQRHQT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TQQIVYHGLVPQLGESGDSESTVHGEGSADVHQATHSHTSGRQTVMTEKSTFQSVVSESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 TQQIVYHGLVPQLGESGDSESTVHGEGSADVHQATHSHTSGRQTVMTEKSTFQSVVSESP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QEDSAGDTSGAEMTSGVSRSFRHIRLGPTETETSEHIAIRGPVSRTFVLAGSADSPELGK
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 QEDSAEDTSGAEMTSGVSRSFRHIRLGPTETETSEHIAIRGPVSRTFVLAGSADSPELGK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD LADSSRTLRHIAPGPKETSFTFQMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LADSSRTLRHIAPGPKETSFTFQMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD VGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 VGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEEN
1510 1520 1530 1540 1550 1560
pF1KSD DGHWF
:::::
NP_663 DGHWF
>>XP_016877524 (OMIM: 606087) PREDICTED: synemin isoform (1200 aa)
initn: 7381 init1: 7381 opt: 7384 Z-score: 4439.5 bits: 833.9 E(85289): 0
Smith-Waterman score: 7384; 99.3% identity (99.6% similar) in 1158 aa overlap (1-1158:1-1158)
10 20 30 40 50 60
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCLEDEKATLTLAMADWLRDYQDLLQV
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_016 ALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENEWNLFSR
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYISEDSTIARESYRDRRDKVA
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD SYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAW
::::::::::: :.:
XP_016 SYEGPTAEVVEFWKLGSLKVPTVSFPGEGSLPGLQTAVFSLCPHMVEREIISLVSLLIKH
1150 1160 1170 1180 1190 1200
>>NP_056101 (OMIM: 606087) synemin isoform B [Homo sapie (1253 aa)
initn: 7456 init1: 7382 opt: 7384 Z-score: 4439.3 bits: 833.9 E(85289): 0
Smith-Waterman score: 7418; 79.9% identity (80.0% similar) in 1565 aa overlap (1-1565:1-1253)
10 20 30 40 50 60
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQREL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 REVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCLEDEKATLTLAMADWLRDYQDLLQV
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_056 ALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENEWNLFSR
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_056 KTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYISEDSTIARESYRDRRDKVA
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_056 SQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGES
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD SYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAW
:::::::::::
NP_056 SYEGPTAEVVE-------------------------------------------------
1150
1210 1220 1230 1240 1250 1260
pF1KSD GSPEPGPAESSADMDGSGRHSTFGCRQFHAEKEIIFQGPISAAGKVGDYFATEESVGTQT
NP_056 ------------------------------------------------------------
1270 1280 1290 1300 1310 1320
pF1KSD SVRQLQLGPKEGFSGQIQFTAPLSDKVELGVIGDSVHMEGLPGSSTSIRHISIGPQRHQT
NP_056 ------------------------------------------------------------
1330 1340 1350 1360 1370 1380
pF1KSD TQQIVYHGLVPQLGESGDSESTVHGEGSADVHQATHSHTSGRQTVMTEKSTFQSVVSESP
NP_056 ------------------------------------------------------------
1390 1400 1410 1420 1430 1440
pF1KSD QEDSAGDTSGAEMTSGVSRSFRHIRLGPTETETSEHIAIRGPVSRTFVLAGSADSPELGK
NP_056 ------------------------------------------------------------
1450 1460 1470 1480 1490 1500
pF1KSD LADSSRTLRHIAPGPKETSFTFQMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQA
:::::::::::::::::::::::::::::::::::::
NP_056 -----------------------MDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQA
1160 1170 1180
1510 1520 1530 1540 1550 1560
pF1KSD VGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEEN
1190 1200 1210 1220 1230 1240
pF1KSD DGHWF
:::::
NP_056 DGHWF
1250
>>XP_006717563 (OMIM: 116300,193060) PREDICTED: vimentin (466 aa)
initn: 494 init1: 269 opt: 488 Z-score: 313.7 bits: 69.1 E(85289): 9.8e-11
Smith-Waterman score: 488; 33.3% identity (64.1% similar) in 312 aa overlap (11-318:103-407)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
::.:::::: :. .:. .:: ::..: .:
XP_006 SVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILL
80 90 100 110 120 130
50 60 70 80 90
pF1KSD EELRGRRGREGLWAEGQARCA----EEARSLRQQLDELSWATALAEGERDALRRELRELQ
::. .: .:..: . :: : ::.:.:.:. : .: ::: : ... .:.
XP_006 AELEQLKG------QGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLR
140 150 160 170 180
100 110 120 130 140 150
pF1KSD RLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELR
. :: : . . : . ......: :: :: . :: : : ::....::.
XP_006 EKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQ
190 200 210 220 230 240
160 170 180 190 200 210
pF1KSD ARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRG
:. ... . .. : ::.:...: ..:.. .:. . :... .: :: :.
XP_006 AQIQEQHVQIDVDVSKPDLTAA-LRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KSD QESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCL
... ::..:. .....: :. .:. :: . .:.:.....: . : .: :
XP_006 NDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRL
310 320 330 340 350 360
280 290 300 310 320 330
pF1KSD EDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSE
.:: .. :: ::.:::::.:: .:..:.:::: :::::
XP_006 QDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRE
370 380 390 400 410 420
340 350 360 370 380 390
pF1KSD FRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARR
XP_006 TNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
430 440 450 460
>>NP_003371 (OMIM: 116300,193060) vimentin [Homo sapiens (466 aa)
initn: 494 init1: 269 opt: 488 Z-score: 313.7 bits: 69.1 E(85289): 9.8e-11
Smith-Waterman score: 488; 33.3% identity (64.1% similar) in 312 aa overlap (11-318:103-407)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
::.:::::: :. .:. .:: ::..: .:
NP_003 SVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILL
80 90 100 110 120 130
50 60 70 80 90
pF1KSD EELRGRRGREGLWAEGQARCA----EEARSLRQQLDELSWATALAEGERDALRRELRELQ
::. .: .:..: . :: : ::.:.:.:. : .: ::: : ... .:.
NP_003 AELEQLKG------QGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLR
140 150 160 170 180
100 110 120 130 140 150
pF1KSD RLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELR
. :: : . . : . ......: :: :: . :: : : ::....::.
NP_003 EKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQ
190 200 210 220 230 240
160 170 180 190 200 210
pF1KSD ARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRG
:. ... . .. : ::.:...: ..:.. .:. . :... .: :: :.
NP_003 AQIQEQHVQIDVDVSKPDLTAA-LRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KSD QESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCL
... ::..:. .....: :. .:. :: . .:.:.....: . : .: :
NP_003 NDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRL
310 320 330 340 350 360
280 290 300 310 320 330
pF1KSD EDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSE
.:: .. :: ::.:::::.:: .:..:.:::: :::::
NP_003 QDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRE
370 380 390 400 410 420
340 350 360 370 380 390
pF1KSD FRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARR
NP_003 TNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
430 440 450 460
>>NP_001124491 (OMIM: 137780,203450) glial fibrillary ac (431 aa)
initn: 389 init1: 159 opt: 460 Z-score: 297.4 bits: 66.0 E(85289): 8e-10
Smith-Waterman score: 460; 34.5% identity (60.4% similar) in 328 aa overlap (11-333:69-387)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
:.::..::: :. .:. .:: ::..: :
NP_001 LARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALA
40 50 60 70 80 90
50 60 70 80 90
pF1KSD EELRGRRGREG--LWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRL
:: :..: : :: : : :: .::.:. .: : ::: : ..: ...
NP_001 AELNQLRAKEPTKLADVYQA----ELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD DAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRAR
.: : . . .:.: ..: .:: :: :: . :. : : : ::..::::. .
NP_001 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD AASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQE
: .: . .. : :.:.. .: ... . .:. . :... .: .: :. :
NP_001 LARQQVHVELDVAKPDLTAA-LKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD SRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMRE--EYGI-QAEERQRAIDC
::..:. .. ..: . ::.::. :. .::: : . .: :.:.
NP_001 LLRQAKHEANDYRRQLQSL---TCDLESLRGTNESLERQMREQEERHVREAASYQEALAR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD LEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPS
::.: .: :: :..:::::.:: .:..:.:::: ::::: : .:.: .. :.
NP_001 LEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEEN-RITIPVQTFSNLQI
340 350 360 370 380
340 350 360 370 380 390
pF1KSD EFRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDAR
NP_001 RGGKSTKDGENHKVTRYLKSLTIRVIPIQAHQIVNGTPPARG
390 400 410 420 430
>>NP_002046 (OMIM: 137780,203450) glial fibrillary acidi (432 aa)
initn: 389 init1: 159 opt: 460 Z-score: 297.4 bits: 66.0 E(85289): 8e-10
Smith-Waterman score: 460; 34.5% identity (60.4% similar) in 328 aa overlap (11-333:69-387)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
:.::..::: :. .:. .:: ::..: :
NP_002 LARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALA
40 50 60 70 80 90
50 60 70 80 90
pF1KSD EELRGRRGREG--LWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRL
:: :..: : :: : : :: .::.:. .: : ::: : ..: ...
NP_002 AELNQLRAKEPTKLADVYQA----ELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD DAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRAR
.: : . . .:.: ..: .:: :: :: . :. : : : ::..::::. .
NP_002 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD AASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQE
: .: . .. : :.:.. .: ... . .:. . :... .: .: :. :
NP_002 LARQQVHVELDVAKPDLTAA-LKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD SRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMRE--EYGI-QAEERQRAIDC
::..:. .. ..: . ::.::. :. .::: : . .: :.:.
NP_002 LLRQAKHEANDYRRQLQSL---TCDLESLRGTNESLERQMREQEERHVREAASYQEALAR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD LEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPS
::.: .: :: :..:::::.:: .:..:.:::: ::::: : .:.: .. :.
NP_002 LEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEEN-RITIPVQTFSNLQI
340 350 360 370 380
340 350 360 370 380 390
pF1KSD EFRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDAR
NP_002 RETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
390 400 410 420 430
>>NP_001229305 (OMIM: 137780,203450) glial fibrillary ac (438 aa)
initn: 389 init1: 159 opt: 460 Z-score: 297.3 bits: 66.0 E(85289): 8e-10
Smith-Waterman score: 460; 34.5% identity (60.4% similar) in 328 aa overlap (11-333:69-387)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
:.::..::: :. .:. .:: ::..: :
NP_001 LARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALA
40 50 60 70 80 90
50 60 70 80 90
pF1KSD EELRGRRGREG--LWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRL
:: :..: : :: : : :: .::.:. .: : ::: : ..: ...
NP_001 AELNQLRAKEPTKLADVYQA----ELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD DAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRAR
.: : . . .:.: ..: .:: :: :: . :. : : : ::..::::. .
NP_001 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD AASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQE
: .: . .. : :.:.. .: ... . .:. . :... .: .: :. :
NP_001 LARQQVHVELDVAKPDLTAA-LKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD SRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMRE--EYGI-QAEERQRAIDC
::..:. .. ..: . ::.::. :. .::: : . .: :.:.
NP_001 LLRQAKHEANDYRRQLQSL---TCDLESLRGTNESLERQMREQEERHVREAASYQEALAR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD LEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPS
::.: .: :: :..:::::.:: .:..:.:::: ::::: : .:.: .. :.
NP_001 LEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEEN-RITIPVQTFSNLQI
340 350 360 370 380
340 350 360 370 380 390
pF1KSD EFRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDAR
NP_001 RGQYSRASWEGHWSPAPSSRACRLLQTGTEDQGKGIQLSLGAFVTLQRS
390 400 410 420 430
>>XP_016879940 (OMIM: 137780,203450) PREDICTED: glial fi (472 aa)
initn: 389 init1: 159 opt: 460 Z-score: 296.9 bits: 66.0 E(85289): 8.5e-10
Smith-Waterman score: 460; 34.5% identity (60.4% similar) in 328 aa overlap (11-333:69-387)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
:.::..::: :. .:. .:: ::..: :
XP_016 LARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALA
40 50 60 70 80 90
50 60 70 80 90
pF1KSD EELRGRRGREG--LWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRL
:: :..: : :: : : :: .::.:. .: : ::: : ..: ...
XP_016 AELNQLRAKEPTKLADVYQA----ELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD DAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRAR
.: : . . .:.: ..: .:: :: :: . :. : : : ::..::::. .
XP_016 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD AASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQE
: .: . .. : :.:.. .: ... . .:. . :... .: .: :. :
XP_016 LARQQVHVELDVAKPDLTAA-LKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD SRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMRE--EYGI-QAEERQRAIDC
::..:. .. ..: . ::.::. :. .::: : . .: :.:.
XP_016 LLRQAKHEANDYRRQLQSL---TCDLESLRGTNESLERQMREQEERHVREAASYQEALAR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD LEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPS
::.: .: :: :..:::::.:: .:..:.:::: ::::: : .:.: .. :.
XP_016 LEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEEN-RITIPVQTFSNLQI
340 350 360 370 380
340 350 360 370 380 390
pF1KSD EFRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDAR
XP_016 RGGKSTKDGENHKVTRYLKSLTIRVIPIQAHQIVNGTPPARETSLDTKSVSEGHLKRNIV
390 400 410 420 430 440
>>NP_006253 (OMIM: 105400,170710) peripherin [Homo sapie (470 aa)
initn: 287 init1: 184 opt: 457 Z-score: 295.1 bits: 65.7 E(85289): 1.1e-09
Smith-Waterman score: 457; 33.7% identity (62.5% similar) in 312 aa overlap (11-318:97-403)
10 20 30 40
pF1KSD MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLE
:: :::::: :. ... .:: ::..: :.
NP_006 AGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALR
70 80 90 100 110 120
50 60 70 80 90
pF1KSD EELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELREL-QRLD
:: ::.: :... : .: : ::..:. :. .. :::.: ..: : :::.
NP_006 GELSQARGQEP--ARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KSD AEERAARGRLDAE--LGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRA
: .: : ::: : ......: .: :: . :. : . : ::...:.:..
NP_006 EE---TRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQV
190 200 210 220 230 240
160 170 180 190 200 210
pF1KSD RAASLTMH-FRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRG
. : .. ...:: ::... .: ..:.. .:. . :... .: .: :.
NP_006 SVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KSD QESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRAIDCL
.:. ::..: .. ..: :. ::. : : ...:.....: : . :
NP_006 HEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARL
310 320 330 340 350 360
280 290 300 310 320 330
pF1KSD EDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSE
:.: : :: ::.::.::.:: .:..:.:::: :::::
NP_006 EEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLNIKT
370 380 390 400 410 420
340 350 360 370 380 390
pF1KSD FRNKSYHYTDSLLQRENEWNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARR
NP_006 TVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSELDKSSAHSY
430 440 450 460 470
1565 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:22:28 2016 done: Thu Nov 3 01:22:31 2016
Total Scan time: 15.750 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]