FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0383, 1781 aa 1>>>pF1KSDA0383 1781 - 1781 aa - 1781 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.6828+/-0.000499; mu= -13.2029+/- 0.031 mean_var=526.3086+/-110.007, 0's: 0 Z-trim(122.0): 152 B-trim: 1165 in 2/60 Lambda= 0.055905 statistics sampled from 39163 (39360) to 39163 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.461), width: 16 Scan time: 16.920 The best scores are: opt bits E(85289) XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 12037 987.2 0 XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 12037 987.2 0 XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 12037 987.2 0 NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 12037 987.2 0 XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 9484 781.3 0 XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 9484 781.3 0 NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 9484 781.3 0 XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 9484 781.3 0 XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 9484 781.3 0 XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 9484 781.3 0 NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 9453 778.8 0 XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 9453 778.8 0 XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 8206 678.2 1.8e-193 XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 8206 678.2 2.1e-193 NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1767 158.9 4.4e-37 XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1767 158.9 4.4e-37 XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1767 158.9 4.4e-37 NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1694 152.7 1.3e-35 XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1702 153.7 1.7e-35 XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1702 153.7 1.7e-35 XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1702 153.7 1.7e-35 XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1702 153.7 1.7e-35 NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1206 113.3 7.5e-24 NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1202 112.8 7.7e-24 XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1196 112.2 8.1e-24 NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1196 112.3 1e-23 NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1196 112.4 1.1e-23 NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1196 112.4 1.3e-23 XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 963 93.4 3.4e-18 XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 963 93.4 3.4e-18 NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 963 93.6 4.8e-18 NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 950 92.5 9.9e-18 NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 950 92.5 1e-17 NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 942 91.9 1.7e-17 XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 942 91.9 1.7e-17 NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 940 91.7 1.7e-17 NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 942 91.9 1.8e-17 XP_016873590 (OMIM: 601671) PREDICTED: zinc finger ( 385) 511 57.0 3.9e-07 NP_001317237 (OMIM: 601671) zinc finger protein ub ( 405) 511 57.1 4.1e-07 XP_016873591 (OMIM: 601671) PREDICTED: zinc finger ( 371) 508 56.8 4.5e-07 NP_006259 (OMIM: 601671) zinc finger protein ubi-d ( 391) 508 56.8 4.7e-07 NP_001267471 (OMIM: 601672) zinc finger protein DP ( 378) 485 54.9 1.7e-06 XP_016877159 (OMIM: 601672) PREDICTED: zinc finger ( 378) 485 54.9 1.7e-06 XP_005259349 (OMIM: 601670) PREDICTED: zinc finger ( 369) 478 54.4 2.4e-06 XP_005259346 (OMIM: 601670) PREDICTED: zinc finger ( 397) 478 54.4 2.5e-06 NP_001128628 (OMIM: 601670) zinc finger protein ne ( 332) 475 54.1 2.6e-06 XP_005259347 (OMIM: 601670) PREDICTED: zinc finger ( 388) 475 54.1 3e-06 NP_001128627 (OMIM: 601670) zinc finger protein ne ( 414) 475 54.2 3.1e-06 NP_579866 (OMIM: 613069) PHD finger protein 10 iso ( 496) 432 50.8 4e-05 NP_060758 (OMIM: 613069) PHD finger protein 10 iso ( 498) 432 50.8 4e-05 >>XP_016871496 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa) initn: 12037 init1: 12037 opt: 12037 Z-score: 5264.0 bits: 987.2 E(85289): 0 Smith-Waterman score: 12037; 99.9% identity (100.0% similar) in 1781 aa overlap (1-1781:1-1781) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 pF1KSD YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::: XP_016 YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 1750 1760 1770 1780 >>XP_016871497 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa) initn: 12037 init1: 12037 opt: 12037 Z-score: 5264.0 bits: 987.2 E(85289): 0 Smith-Waterman score: 12037; 99.9% identity (100.0% similar) in 1781 aa overlap (1-1781:1-1781) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 pF1KSD YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::: XP_016 YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 1750 1760 1770 1780 >>XP_016871495 (OMIM: 603736,605880,606170) PREDICTED: h (1781 aa) initn: 12037 init1: 12037 opt: 12037 Z-score: 5264.0 bits: 987.2 E(85289): 0 Smith-Waterman score: 12037; 99.9% identity (100.0% similar) in 1781 aa overlap (1-1781:1-1781) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 pF1KSD YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::: XP_016 YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 1750 1760 1770 1780 >>NP_001243398 (OMIM: 603736,605880,606170) histone acet (1781 aa) initn: 12037 init1: 12037 opt: 12037 Z-score: 5264.0 bits: 987.2 E(85289): 0 Smith-Waterman score: 12037; 99.9% identity (100.0% similar) in 1781 aa overlap (1-1781:1-1781) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKEL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQES 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSC 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNANI 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQR 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLM 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 pF1KSD YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::: NP_001 YAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 1750 1760 1770 1780 >>XP_016871491 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: XP_016 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: XP_016 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ XP_016 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ XP_016 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ XP_016 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ XP_016 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: XP_016 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 >>XP_016871489 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: XP_016 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: XP_016 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ XP_016 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ XP_016 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ XP_016 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ XP_016 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: XP_016 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 >>NP_036462 (OMIM: 603736,605880,606170) histone acetylt (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: NP_036 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: NP_036 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ NP_036 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ NP_036 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ NP_036 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ NP_036 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: NP_036 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: NP_036 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: NP_036 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 >>XP_016871492 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: XP_016 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: XP_016 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ XP_016 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ XP_016 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ XP_016 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ XP_016 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: XP_016 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 >>XP_016871490 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: XP_016 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: XP_016 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ XP_016 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ XP_016 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ XP_016 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ XP_016 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: XP_016 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: XP_016 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 >>XP_005269721 (OMIM: 603736,605880,606170) PREDICTED: h (2073 aa) initn: 9453 init1: 9453 opt: 9484 Z-score: 4150.2 bits: 781.3 E(85289): 0 Smith-Waterman score: 9683; 83.8% identity (83.9% similar) in 1813 aa overlap (261-1781:261-2073) 240 250 260 270 280 290 pF1KSD PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS :::::::::::::::::::::::::::::: XP_005 PEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLK 300 310 320 330 340 350 360 370 pF1KSD QRLLSVTSDEGSMNAFTGRGSP-------------------------------------- :::::::::::::::::::::: XP_005 QRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGAT 360 370 380 390 400 410 pF1KSD ------------------------------------------------------------ XP_005 TKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQ 420 430 440 450 460 470 pF1KSD ------------------------------------------------------------ XP_005 KQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPS 480 490 500 510 520 530 pF1KSD ------------------------------------------------------------ XP_005 LSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGK 540 550 560 570 580 590 pF1KSD ------------------------------------------------------------ XP_005 RDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGK 600 610 620 630 640 650 380 390 400 410 pF1KSD --------------DTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE :::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECE 660 670 680 690 700 710 420 430 440 450 460 470 pF1KSD SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKK 720 730 740 750 760 770 480 490 500 510 520 530 pF1KSD CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLT 780 790 800 810 820 830 540 550 560 570 580 590 pF1KSD KNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSP 840 850 860 870 880 890 600 610 620 630 640 650 pF1KSD EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDK 900 910 920 930 940 950 660 670 680 690 700 710 pF1KSD RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAER 960 970 980 990 1000 1010 720 730 740 750 760 770 pF1KSD LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSE 1020 1030 1040 1050 1060 1070 780 790 800 810 820 830 pF1KSD EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1080 1090 1100 1110 1120 1130 840 850 860 870 880 890 pF1KSD KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLR 1140 1150 1160 1170 1180 1190 900 910 920 930 940 950 pF1KSD KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPK 1200 1210 1220 1230 1240 1250 960 970 980 990 1000 1010 pF1KSD GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEE 1260 1270 1280 1290 1300 1310 1020 1030 1040 1050 1060 1070 pF1KSD VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGE 1320 1330 1340 1350 1360 1370 1080 1090 1100 1110 1120 1130 pF1KSD EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDED 1380 1390 1400 1410 1420 1430 1140 1150 1160 1170 1180 1190 pF1KSD DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPK 1440 1450 1460 1470 1480 1490 1200 1210 1220 1230 1240 1250 pF1KSD ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQ 1500 1510 1520 1530 1540 1550 1260 1270 1280 1290 1300 1310 pF1KSD ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQS 1560 1570 1580 1590 1600 1610 1320 1330 1340 1350 1360 1370 pF1KSD VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDL 1620 1630 1640 1650 1660 1670 1380 1390 1400 1410 1420 1430 pF1KSD GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISG 1680 1690 1700 1710 1720 1730 1440 1450 1460 1470 1480 1490 pF1KSD SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETSNA 1740 1750 1760 1770 1780 1790 1500 1510 1520 1530 1540 1550 pF1KSD NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLS 1800 1810 1820 1830 1840 1850 1560 1570 1580 1590 1600 1610 pF1KSD TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHS 1860 1870 1880 1890 1900 1910 1620 1630 1640 1650 1660 1670 pF1KSD QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVN 1920 1930 1940 1950 1960 1970 1680 1690 1700 1710 1720 1730 pF1KSD LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGT 1980 1990 2000 2010 2020 2030 1740 1750 1760 1770 1780 pF1KSD QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR ::::::::::::::::::::::::::::::::::::::::::: XP_005 QPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR 2040 2050 2060 2070 >-- initn: 1760 init1: 1760 opt: 1760 Z-score: 783.4 bits: 158.4 E(85289): 6.7e-37 Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KSD MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC :::::::::::::::::::: XP_005 GSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECC 250 260 270 280 290 300 1781 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:32:05 2016 done: Thu Nov 3 01:32:08 2016 Total Scan time: 16.920 Total Display time: 1.340 Function used was FASTA [36.3.4 Apr, 2011]