FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0387, 1038 aa 1>>>pF1KSDA0387 1038 - 1038 aa - 1038 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5632+/-0.000401; mu= 7.2335+/- 0.025 mean_var=193.2360+/-39.522, 0's: 0 Z-trim(118.9): 415 B-trim: 330 in 1/55 Lambda= 0.092264 statistics sampled from 31801 (32252) to 31801 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.378), width: 16 Scan time: 14.930 The best scores are: opt bits E(85289) NP_001295197 (OMIM: 601698) receptor-type tyrosine (1038) 6944 937.7 0 NP_002838 (OMIM: 601698) receptor-type tyrosine-pr (1015) 6527 882.2 0 NP_570857 (OMIM: 601698) receptor-type tyrosine-pr ( 998) 6404 865.8 0 XP_016867964 (OMIM: 601698) PREDICTED: receptor-ty ( 949) 6314 853.8 0 NP_001295196 (OMIM: 601698) receptor-type tyrosine ( 977) 6150 832.0 0 XP_016867965 (OMIM: 601698) PREDICTED: receptor-ty ( 866) 5300 718.8 3.2e-206 XP_011514748 (OMIM: 601698) PREDICTED: receptor-ty ( 834) 5281 716.3 1.8e-205 XP_011514750 (OMIM: 601698) PREDICTED: receptor-ty ( 663) 3565 487.8 8.5e-137 XP_011514749 (OMIM: 601698) PREDICTED: receptor-ty ( 703) 3565 487.8 8.9e-137 XP_011514751 (OMIM: 601698) PREDICTED: receptor-ty ( 593) 3424 469.0 3.5e-131 NP_570858 (OMIM: 601698) receptor-type tyrosine-pr ( 986) 3228 443.1 3.7e-123 NP_001186693 (OMIM: 601773) receptor-type tyrosine ( 889) 2253 313.2 4e-84 NP_002837 (OMIM: 601773) receptor-type tyrosine-pr ( 979) 2253 313.3 4.3e-84 XP_016860098 (OMIM: 601773) PREDICTED: receptor-ty ( 980) 2249 312.7 6.2e-84 NP_001186692 (OMIM: 601773) receptor-type tyrosine ( 950) 2131 297.0 3.3e-79 XP_016860099 (OMIM: 601773) PREDICTED: receptor-ty ( 951) 2128 296.6 4.3e-79 XP_016860101 (OMIM: 601773) PREDICTED: receptor-ty ( 877) 1890 264.9 1.4e-69 XP_011509868 (OMIM: 601773) PREDICTED: receptor-ty ( 906) 1862 261.2 1.9e-68 XP_016860100 (OMIM: 601773) PREDICTED: receptor-ty ( 907) 1862 261.2 1.9e-68 XP_016883101 (OMIM: 608712) PREDICTED: receptor-ty (1455) 666 102.1 2.3e-20 NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 664 101.9 2.7e-20 XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 662 101.6 3.2e-20 NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 662 101.6 3.3e-20 XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436) 656 100.8 5.7e-20 XP_011534318 (OMIM: 602545) PREDICTED: receptor-ty (1456) 656 100.8 5.8e-20 XP_011526459 (OMIM: 601576) PREDICTED: receptor-ty (1517) 656 100.8 6e-20 XP_016882563 (OMIM: 601576) PREDICTED: receptor-ty (1521) 656 100.8 6e-20 XP_016882558 (OMIM: 601576) PREDICTED: receptor-ty (1930) 656 100.9 7.2e-20 XP_005259657 (OMIM: 601576) PREDICTED: receptor-ty (1935) 656 100.9 7.2e-20 XP_005259667 (OMIM: 601576) PREDICTED: receptor-ty (1497) 653 100.4 7.8e-20 XP_016866639 (OMIM: 602545) PREDICTED: receptor-ty ( 723) 646 99.3 8.4e-20 XP_016866638 (OMIM: 602545) PREDICTED: receptor-ty ( 727) 646 99.3 8.4e-20 XP_005259664 (OMIM: 601576) PREDICTED: receptor-ty (1906) 653 100.5 9.4e-20 XP_016882561 (OMIM: 601576) PREDICTED: receptor-ty (1910) 653 100.5 9.4e-20 NP_573400 (OMIM: 608712) receptor-type tyrosine-pr (1460) 649 99.9 1.1e-19 XP_016866636 (OMIM: 602545) PREDICTED: receptor-ty (1374) 646 99.5 1.4e-19 XP_016866635 (OMIM: 602545) PREDICTED: receptor-ty (1375) 646 99.5 1.4e-19 XP_016866634 (OMIM: 602545) PREDICTED: receptor-ty (1375) 646 99.5 1.4e-19 XP_011534319 (OMIM: 602545) PREDICTED: receptor-ty (1391) 646 99.5 1.4e-19 XP_011534320 (OMIM: 602545) PREDICTED: receptor-ty (1391) 646 99.5 1.4e-19 XP_006715600 (OMIM: 602545) PREDICTED: receptor-ty (1445) 646 99.5 1.4e-19 NP_001129120 (OMIM: 602545) receptor-type tyrosine (1446) 646 99.5 1.4e-19 XP_011534317 (OMIM: 602545) PREDICTED: receptor-ty (1458) 646 99.5 1.5e-19 XP_011534316 (OMIM: 602545) PREDICTED: receptor-ty (1461) 646 99.5 1.5e-19 NP_001278910 (OMIM: 602545) receptor-type tyrosine (1462) 646 99.5 1.5e-19 NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441) 645 99.4 1.6e-19 XP_011524018 (OMIM: 176888) PREDICTED: receptor-ty (1239) 640 98.6 2.2e-19 XP_016881398 (OMIM: 176888) PREDICTED: receptor-ty (1248) 640 98.6 2.2e-19 XP_011524024 (OMIM: 176888) PREDICTED: receptor-ty (1252) 640 98.6 2.2e-19 XP_016881397 (OMIM: 176888) PREDICTED: receptor-ty (1264) 640 98.6 2.3e-19 >>NP_001295197 (OMIM: 601698) receptor-type tyrosine-pro (1038 aa) initn: 6944 init1: 6944 opt: 6944 Z-score: 5004.9 bits: 937.7 E(85289): 0 Smith-Waterman score: 6944; 99.8% identity (99.9% similar) in 1038 aa overlap (1-1038:1-1038) 10 20 30 40 50 60 pF1KSD MAVESEYSLLRTEASFPTMKMFCVSHTLPRVEVMFVSGPQTRERTEPVDPRWQCLVQMWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVESEYSLLRTEASFPTMKMFCVSHTLPRVEVMFVSGPQTRERTEPVDPRWQCLVQMWA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQLHEDLL :::::::::::::::::::::::::::::::::::::::::::::::::: ::::.:::: NP_001 LEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGSRTQLREDLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVTD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQNVTTEDVEKATVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQNVTTEDVEKATVDN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD CLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEF 970 980 990 1000 1010 1020 1030 pF1KSD ALTAVAEEVNAILKALPQ :::::::::::::::::: NP_001 ALTAVAEEVNAILKALPQ 1030 >>NP_002838 (OMIM: 601698) receptor-type tyrosine-protei (1015 aa) initn: 6527 init1: 6527 opt: 6527 Z-score: 4705.1 bits: 882.2 E(85289): 0 Smith-Waterman score: 6527; 99.8% identity (99.9% similar) in 978 aa overlap (61-1038:38-1015) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: NP_002 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: NP_002 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA 550 560 570 580 590 600 640 650 660 670 680 690 pF1KSD EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ 610 620 630 640 650 660 700 710 720 730 740 750 pF1KSD ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST 670 680 690 700 710 720 760 770 780 790 800 810 pF1KSD GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV 730 740 750 760 770 780 820 830 840 850 860 870 pF1KSD LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP 790 800 810 820 830 840 880 890 900 910 920 930 pF1KSD LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH 850 860 870 880 890 900 940 950 960 970 980 990 pF1KSD FLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAK 910 920 930 940 950 960 1000 1010 1020 1030 pF1KSD GAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ :::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 970 980 990 1000 1010 >>NP_570857 (OMIM: 601698) receptor-type tyrosine-protei (998 aa) initn: 6404 init1: 6404 opt: 6404 Z-score: 4616.7 bits: 865.8 E(85289): 0 Smith-Waterman score: 6404; 99.8% identity (99.9% similar) in 961 aa overlap (78-1038:38-998) 50 60 70 80 90 100 pF1KSD VDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRV :::::::::::::::::::::::::::::: NP_570 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLDGVFGRCQKVPAMDFYRYEVSPVALQRLRV 10 20 30 40 50 60 110 120 130 140 150 160 pF1KSD ALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 ALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGG 70 80 90 100 110 120 170 180 190 200 210 220 pF1KSD AALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 AALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTY 130 140 150 160 170 180 230 240 250 260 270 280 pF1KSD PPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLE ::: ::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 PPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLE 190 200 210 220 230 240 290 300 310 320 330 340 pF1KSD PQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 PQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGL 250 260 270 280 290 300 350 360 370 380 390 400 pF1KSD SGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 SGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDD 310 320 330 340 350 360 410 420 430 440 450 460 pF1KSD DDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 DDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGV 370 380 390 400 410 420 470 480 490 500 510 520 pF1KSD ENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 ENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQ 430 440 450 460 470 480 530 540 550 560 570 580 pF1KSD PSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 PSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQN 490 500 510 520 530 540 590 600 610 620 630 640 pF1KSD VTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 VTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLA 550 560 570 580 590 600 650 660 670 680 690 700 pF1KSD CILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 CILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEG 610 620 630 640 650 660 710 720 730 740 750 760 pF1KSD PHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 PHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNR 670 680 690 700 710 720 770 780 790 800 810 820 pF1KSD LEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 LEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINAS 730 740 750 760 770 780 830 840 850 860 870 880 pF1KSD PIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 PIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEG 790 800 810 820 830 840 890 900 910 920 930 940 pF1KSD SNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 SNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLL 850 860 870 880 890 900 950 960 970 980 990 1000 pF1KSD DFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_570 DFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQ 910 920 930 940 950 960 1010 1020 1030 pF1KSD RPGMVQTKEQFEFALTAVAEEVNAILKALPQ ::::::::::::::::::::::::::::::: NP_570 RPGMVQTKEQFEFALTAVAEEVNAILKALPQ 970 980 990 >>XP_016867964 (OMIM: 601698) PREDICTED: receptor-type t (949 aa) initn: 6314 init1: 6314 opt: 6314 Z-score: 4552.3 bits: 853.8 E(85289): 0 Smith-Waterman score: 6314; 99.8% identity (99.9% similar) in 949 aa overlap (90-1038:1-949) 60 70 80 90 100 110 pF1KSD AGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTW :::::::::::::::::::::::::::::: XP_016 MDFYRYEVSPVALQRLRVALQKLSGTGFTW 10 20 30 120 130 140 150 160 170 pF1KSD QDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD FLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQLHEDL ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::.::: XP_016 FLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGSRTQLREDL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD LPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMP 160 170 180 190 200 210 300 310 320 330 340 350 pF1KSD RPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELM 220 230 240 250 260 270 360 370 380 390 400 410 pF1KSD AGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLS 280 290 300 310 320 330 420 430 440 450 460 470 pF1KSD ATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDL 340 350 360 370 380 390 480 490 500 510 520 530 pF1KSD LGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVT 400 410 420 430 440 450 540 550 560 570 580 590 pF1KSD DRDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQNVTTEDVEKATVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQNVTTEDVEKATVD 460 470 480 490 500 510 600 610 620 630 640 650 pF1KSD NKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLI 520 530 540 550 560 570 660 670 680 690 700 710 pF1KSD YCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQ 580 590 600 610 620 630 720 730 740 750 760 770 pF1KSD FSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQ 640 650 660 670 680 690 780 790 800 810 820 830 pF1KSD AEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAY 700 710 720 730 740 750 840 850 860 870 880 890 pF1KSD IATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLV 760 770 780 790 800 810 900 910 920 930 940 950 pF1KSD SEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRG 820 830 840 850 860 870 960 970 980 990 1000 1010 pF1KSD RSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFE 880 890 900 910 920 930 1020 1030 pF1KSD FALTAVAEEVNAILKALPQ ::::::::::::::::::: XP_016 FALTAVAEEVNAILKALPQ 940 >>NP_001295196 (OMIM: 601698) receptor-type tyrosine-pro (977 aa) initn: 6259 init1: 6150 opt: 6150 Z-score: 4434.1 bits: 832.0 E(85289): 0 Smith-Waterman score: 6187; 95.9% identity (96.0% similar) in 978 aa overlap (61-1038:38-977) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM ::::::::::::::::: NP_001 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVN------------- 10 20 30 40 50 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR ::::::::::::::::::::::::::::::::::: NP_001 -------------------------GFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 60 70 80 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 90 100 110 120 130 140 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: NP_001 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 150 160 170 180 190 200 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 210 220 230 240 250 260 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 270 280 290 300 310 320 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 330 340 350 360 370 380 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 390 400 410 420 430 440 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 450 460 470 480 490 500 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA 510 520 530 540 550 560 640 650 660 670 680 690 pF1KSD EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ 570 580 590 600 610 620 700 710 720 730 740 750 pF1KSD ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST 630 640 650 660 670 680 760 770 780 790 800 810 pF1KSD GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV 690 700 710 720 730 740 820 830 840 850 860 870 pF1KSD LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP 750 760 770 780 790 800 880 890 900 910 920 930 pF1KSD LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH 810 820 830 840 850 860 940 950 960 970 980 990 pF1KSD FLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAK 870 880 890 900 910 920 1000 1010 1020 1030 pF1KSD GAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 930 940 950 960 970 >>XP_016867965 (OMIM: 601698) PREDICTED: receptor-type t (866 aa) initn: 5280 init1: 5280 opt: 5300 Z-score: 3823.4 bits: 718.8 E(85289): 3.2e-206 Smith-Waterman score: 5300; 97.4% identity (98.5% similar) in 820 aa overlap (61-880:38-856) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: XP_016 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: XP_016 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA 550 560 570 580 590 600 640 650 660 670 680 690 pF1KSD EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ 610 620 630 640 650 660 700 710 720 730 740 750 pF1KSD ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST 670 680 690 700 710 720 760 770 780 790 800 810 pF1KSD GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV 730 740 750 760 770 780 820 830 840 850 860 870 pF1KSD LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP :::::::::::::::::::::::::::::::::::::::::::::. : ::. .: XP_016 LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQQD-PSTSSVILSWSP 790 800 810 820 830 840 880 890 900 910 920 930 pF1KSD LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH ... .: :. XP_016 VGHLKARPCFSTRRKPRSHR 850 860 >>XP_011514748 (OMIM: 601698) PREDICTED: receptor-type t (834 aa) initn: 5355 init1: 5281 opt: 5281 Z-score: 3810.0 bits: 716.3 E(85289): 1.8e-205 Smith-Waterman score: 5281; 99.5% identity (99.7% similar) in 797 aa overlap (61-857:38-834) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: XP_011 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: XP_011 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA 550 560 570 580 590 600 640 650 660 670 680 690 pF1KSD EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQ 610 620 630 640 650 660 700 710 720 730 740 750 pF1KSD ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDIST 670 680 690 700 710 720 760 770 780 790 800 810 pF1KSD GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRV 730 740 750 760 770 780 820 830 840 850 860 870 pF1KSD LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTP ::::::::::::::::::::::::::::::::::::::::::::: . XP_011 LLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQGI 790 800 810 820 830 880 890 900 910 920 930 pF1KSD LAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFH >>XP_011514750 (OMIM: 601698) PREDICTED: receptor-type t (663 aa) initn: 3565 init1: 3565 opt: 3565 Z-score: 2576.9 bits: 487.8 E(85289): 8.5e-137 Smith-Waterman score: 3565; 99.6% identity (99.8% similar) in 537 aa overlap (61-597:38-574) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: XP_011 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: XP_011 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA ::::::::::::::::::::::::::: XP_011 EVLGPAVTFKVSANVQNVTTEDVEKATARECQSSEGPFLKIYMMIHTARLASESPGPVIV 550 560 570 580 590 600 >>XP_011514749 (OMIM: 601698) PREDICTED: receptor-type t (703 aa) initn: 3565 init1: 3565 opt: 3565 Z-score: 2576.6 bits: 487.8 E(85289): 8.9e-137 Smith-Waterman score: 3565; 99.6% identity (99.8% similar) in 537 aa overlap (61-597:38-574) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: XP_011 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: XP_011 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KSD EVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQA ::::::::::::::::::::::::::: XP_011 EVLGPAVTFKVSANVQNVTTEDVEKATAFATGRAAWSRWTARPTKPPTLTLQPVTETFSQ 550 560 570 580 590 600 >>XP_011514751 (OMIM: 601698) PREDICTED: receptor-type t (593 aa) initn: 3481 init1: 3407 opt: 3424 Z-score: 2476.2 bits: 469.0 E(85289): 3.5e-131 Smith-Waterman score: 3424; 92.6% identity (96.4% similar) in 557 aa overlap (61-611:38-592) 40 50 60 70 80 90 pF1KSD VEVMFVSGPQTRERTEPVDPRWQCLVQMWAGCLLEEGLCGASEACVNDGVFGRCQKVPAM :::::::::::::::::::::::::::::: XP_011 LLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAM 10 20 30 40 50 60 100 110 120 130 140 150 pF1KSD DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPAR 70 80 90 100 110 120 160 170 180 190 200 210 pF1KSD PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDR 130 140 150 160 170 180 220 230 240 250 260 270 pF1KSD FSESILTYVAHTSALTYPPGPRTQLHEDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS :::::::::::::::::::: ::::.:::::::::::::::::::::::::::::::::: XP_011 FSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALS 190 200 210 220 230 240 280 290 300 310 320 330 pF1KSD AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARI 250 260 270 280 290 300 340 350 360 370 380 390 pF1KSD HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGP 310 320 330 340 350 360 400 410 420 430 440 450 pF1KSD KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKK 370 380 390 400 410 420 460 470 480 490 500 510 pF1KSD SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSL 430 440 450 460 470 480 520 530 540 550 560 570 pF1KSD PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADV 490 500 510 520 530 540 580 590 600 610 620 pF1KSD EVLGPAVTFKVSANV------QNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLK . . .: .: :. :... . .... ...:. . ..::: XP_011 DSI--QTTQRVRKNLHDLYIRQKTNIQTLQRTHISKKQTVPSNNGLKT 550 560 570 580 590 630 640 650 660 670 680 pF1KSD FLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGAD 1038 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:34:22 2016 done: Thu Nov 3 01:34:24 2016 Total Scan time: 14.930 Total Display time: 0.310 Function used was FASTA [36.3.4 Apr, 2011]