FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0457, 832 aa 1>>>pF1KSDA0457 832 - 832 aa - 832 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3184+/-0.000843; mu= 8.3918+/- 0.051 mean_var=198.5762+/-39.199, 0's: 0 Z-trim(114.0): 40 B-trim: 0 in 0/55 Lambda= 0.091015 statistics sampled from 14608 (14635) to 14608 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.45), width: 16 Scan time: 3.420 The best scores are: opt bits E(32554) CCDS53483.1 DISC1 gene_id:27185|Hs108|chr1 ( 695) 4429 594.4 2.2e-169 CCDS53482.1 DISC1 gene_id:27185|Hs108|chr1 ( 755) 4420 593.3 5.2e-169 CCDS59205.1 DISC1 gene_id:27185|Hs108|chr1 ( 662) 4418 593.0 5.6e-169 CCDS31055.1 DISC1 gene_id:27185|Hs108|chr1 ( 678) 4418 593.0 5.7e-169 CCDS53484.1 DISC1 gene_id:27185|Hs108|chr1 ( 579) 3814 513.6 3.8e-145 CCDS53485.1 DISC1 gene_id:27185|Hs108|chr1 ( 559) 3697 498.2 1.6e-140 CCDS59206.1 DISC1 gene_id:27185|Hs108|chr1 ( 356) 2436 332.5 7.8e-91 CCDS31056.1 DISC1 gene_id:27185|Hs108|chr1 ( 369) 2436 332.5 8e-91 CCDS59207.1 DISC1 gene_id:27185|Hs108|chr1 ( 201) 1119 159.4 5.7e-39 >>CCDS53483.1 DISC1 gene_id:27185|Hs108|chr1 (695 aa) initn: 4427 init1: 4427 opt: 4429 Z-score: 3154.6 bits: 594.4 E(32554): 2.2e-169 Smith-Waterman score: 4429; 97.5% identity (98.2% similar) in 682 aa overlap (1-682:1-680) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS53 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER .:: . . : :: .: CCDS53 AASV--HCLGKCGKLTWKLVDCLSRAYSSRKPGEACL 670 680 690 >>CCDS53482.1 DISC1 gene_id:27185|Hs108|chr1 (755 aa) initn: 4456 init1: 4420 opt: 4420 Z-score: 3147.8 bits: 593.3 E(32554): 5.2e-169 Smith-Waterman score: 4420; 99.7% identity (100.0% similar) in 661 aa overlap (1-661:1-661) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS53 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER . CCDS53 DGVSLCRPVWSAVVRSCSLQPLPPEFKQFSCLSLRSSWDYRCPPPCLANFVFLVEMGFYH 670 680 690 700 710 720 >>CCDS59205.1 DISC1 gene_id:27185|Hs108|chr1 (662 aa) initn: 4418 init1: 4418 opt: 4418 Z-score: 3147.1 bits: 593.0 E(32554): 5.6e-169 Smith-Waterman score: 4418; 99.8% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS59 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER CCDS59 GR >>CCDS31055.1 DISC1 gene_id:27185|Hs108|chr1 (678 aa) initn: 4418 init1: 4418 opt: 4418 Z-score: 3147.0 bits: 593.0 E(32554): 5.7e-169 Smith-Waterman score: 4418; 99.8% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS31 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER CCDS31 GYKYCDAESWTQRSQQLA 670 >>CCDS53484.1 DISC1 gene_id:27185|Hs108|chr1 (579 aa) initn: 3850 init1: 3814 opt: 3814 Z-score: 2719.3 bits: 513.6 E(32554): 3.8e-145 Smith-Waterman score: 3814; 97.9% identity (99.1% similar) in 576 aa overlap (1-576:1-576) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS53 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH ::::::::::::::::::::::: .: .. .. :. CCDS53 ETIRSLQERIKSLNLSLKEITTKETISGRLKTSPRRLDH 550 560 570 610 620 630 640 650 660 pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY >>CCDS53485.1 DISC1 gene_id:27185|Hs108|chr1 (559 aa) initn: 3697 init1: 3697 opt: 3697 Z-score: 2636.5 bits: 498.2 E(32554): 1.6e-140 Smith-Waterman score: 3697; 99.8% identity (100.0% similar) in 544 aa overlap (1-544:1-544) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS53 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH :::: CCDS53 ETIRRNKCEGKYYEVHGNT 550 >>CCDS59206.1 DISC1 gene_id:27185|Hs108|chr1 (356 aa) initn: 2472 init1: 2436 opt: 2436 Z-score: 1744.3 bits: 332.5 E(32554): 7.8e-91 Smith-Waterman score: 2436; 99.4% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS59 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::. CCDS59 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELRRYNKD 310 320 330 340 350 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA >>CCDS31056.1 DISC1 gene_id:27185|Hs108|chr1 (369 aa) initn: 2472 init1: 2436 opt: 2436 Z-score: 1744.1 bits: 332.5 E(32554): 8e-91 Smith-Waterman score: 2436; 99.4% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS31 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL :::::::::::::::::::::::::::::::::::::::::::::::::. CCDS31 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMELEPIALDPPWK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA CCDS31 PRHPEPNSY >>CCDS59207.1 DISC1 gene_id:27185|Hs108|chr1 (201 aa) initn: 1265 init1: 1119 opt: 1119 Z-score: 813.1 bits: 159.4 E(32554): 5.7e-39 Smith-Waterman score: 1119; 100.0% identity (100.0% similar) in 172 aa overlap (373-544:23-194) 350 360 370 380 390 400 pF1KSD RNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALS :::::::::::::::::::::::::::::: CCDS59 MPGGGPQGAPAAAGGGGVSHRAAETLQQRLEDLEQEKISLHFQLPSRQPALS 10 20 30 40 50 410 420 430 440 450 460 pF1KSD SFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEK 60 70 80 90 100 110 470 480 490 500 510 520 pF1KSD QQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKA 120 130 140 150 160 170 530 540 550 560 570 580 pF1KSD LQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIE :::::::::::::::::::::: CCDS59 LQDTLASAGQIPFHAEPPETIRRKPFLDG 180 190 200 832 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:47:23 2016 done: Thu Nov 3 01:47:24 2016 Total Scan time: 3.420 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]