Result of FASTA (omim) for pF1KSDA0470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0470, 1460 aa
  1>>>pF1KSDA0470 1460 - 1460 aa - 1460 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.3532+/-0.00046; mu= -1.9460+/- 0.028
 mean_var=215.8966+/-44.114, 0's: 0 Z-trim(115.7): 120  B-trim: 167 in 1/60
 Lambda= 0.087287
 statistics sampled from 26228 (26349) to 26228 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.309), width:  16
 Scan time: 14.500

The best scores are:                                      opt bits E(85289)
NP_001035864 (OMIM: 613023) centrosomal protein of (1460) 9409 1199.2       0
XP_016858437 (OMIM: 613023) PREDICTED: centrosomal (1450) 7813 998.2       0
XP_016858436 (OMIM: 613023) PREDICTED: centrosomal (1450) 7813 998.2       0
XP_016858438 (OMIM: 613023) PREDICTED: centrosomal (1433) 7709 985.1       0
XP_016858434 (OMIM: 613023) PREDICTED: centrosomal (1469) 7242 926.3       0
NP_001035863 (OMIM: 613023) centrosomal protein of (1486) 7242 926.3       0
XP_011542646 (OMIM: 613023) PREDICTED: centrosomal (1496) 7242 926.3       0
XP_016858433 (OMIM: 613023) PREDICTED: centrosomal (1496) 7242 926.3       0
XP_016858430 (OMIM: 613023) PREDICTED: centrosomal (1558) 6619 847.8       0
XP_016858426 (OMIM: 613023) PREDICTED: centrosomal (1558) 6619 847.8       0
XP_011542641 (OMIM: 613023) PREDICTED: centrosomal (1620) 6617 847.6       0
XP_011542645 (OMIM: 613023) PREDICTED: centrosomal (1497) 5780 742.2 7.2e-213
XP_016858427 (OMIM: 613023) PREDICTED: centrosomal (1548) 5023 646.8 3.7e-184
XP_011542642 (OMIM: 613023) PREDICTED: centrosomal (1610) 5021 646.6 4.5e-184
XP_016858432 (OMIM: 613023) PREDICTED: centrosomal (1531) 4919 633.7 3.2e-180
XP_016858431 (OMIM: 613023) PREDICTED: centrosomal (1531) 4919 633.7 3.2e-180
XP_011542644 (OMIM: 613023) PREDICTED: centrosomal (1593) 4917 633.5 3.9e-180
XP_016858440 (OMIM: 613023) PREDICTED: centrosomal (1337) 4818 621.0 1.9e-176
XP_016858439 (OMIM: 613023) PREDICTED: centrosomal (1408) 4465 576.6 4.8e-163
XP_016858435 (OMIM: 613023) PREDICTED: centrosomal (1435) 4465 576.6 4.9e-163
XP_016858429 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162
XP_016858424 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162
XP_016858428 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162
NP_055627 (OMIM: 613023) centrosomal protein of 17 (1584) 4452 574.9 1.7e-162
XP_016858425 (OMIM: 613023) PREDICTED: centrosomal (1584) 4452 574.9 1.7e-162
XP_016858423 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162
XP_016858422 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162
XP_011542643 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162
XP_011542640 (OMIM: 613023) PREDICTED: centrosomal (1629) 4450 574.7  2e-162
XP_011542639 (OMIM: 613023) PREDICTED: centrosomal (1646) 4450 574.7  2e-162
XP_011542637 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162
XP_011542638 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162
XP_011542636 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162
XP_006711906 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162
XP_016858421 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162


>>NP_001035864 (OMIM: 613023) centrosomal protein of 170  (1460 aa)
 initn: 9409 init1: 9409 opt: 9409  Z-score: 6412.7  bits: 1199.2 E(85289):    0
Smith-Waterman score: 9409; 99.9% identity (100.0% similar) in 1460 aa overlap (1-1460:1-1460)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
             1390      1400      1410      1420      1430      1440

             1450      1460
pF1KSD SIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::
NP_001 SIHFNRFNPDGEEEDVTVQE
             1450      1460

>>XP_016858437 (OMIM: 613023) PREDICTED: centrosomal pro  (1450 aa)
 initn: 7813 init1: 7813 opt: 7813  Z-score: 5326.5  bits: 998.2 E(85289):    0
Smith-Waterman score: 9306; 99.2% identity (99.3% similar) in 1460 aa overlap (1-1460:1-1450)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
       :::::::::::::::::::          :::::::::::::::::::::::::::::::
XP_016 TTVSTAATTPGSAIDTREE----------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
             1210                1220      1230      1240      1250

             1270      1280      1290      1300      1310      1320
pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
             1260      1270      1280      1290      1300      1310

             1330      1340      1350      1360      1370      1380
pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
             1320      1330      1340      1350      1360      1370

             1390      1400      1410      1420      1430      1440
pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
             1380      1390      1400      1410      1420      1430

             1450      1460
pF1KSD SIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::
XP_016 SIHFNRFNPDGEEEDVTVQE
             1440      1450

>>XP_016858436 (OMIM: 613023) PREDICTED: centrosomal pro  (1450 aa)
 initn: 7813 init1: 7813 opt: 7813  Z-score: 5326.5  bits: 998.2 E(85289):    0
Smith-Waterman score: 9306; 99.2% identity (99.3% similar) in 1460 aa overlap (1-1460:1-1450)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
       :::::::::::::::::::          :::::::::::::::::::::::::::::::
XP_016 TTVSTAATTPGSAIDTREE----------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
             1210                1220      1230      1240      1250

             1270      1280      1290      1300      1310      1320
pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
             1260      1270      1280      1290      1300      1310

             1330      1340      1350      1360      1370      1380
pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
             1320      1330      1340      1350      1360      1370

             1390      1400      1410      1420      1430      1440
pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
             1380      1390      1400      1410      1420      1430

             1450      1460
pF1KSD SIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::
XP_016 SIHFNRFNPDGEEEDVTVQE
             1440      1450

>>XP_016858438 (OMIM: 613023) PREDICTED: centrosomal pro  (1433 aa)
 initn: 7743 init1: 7709 opt: 7709  Z-score: 5255.8  bits: 985.1 E(85289):    0
Smith-Waterman score: 9172; 98.1% identity (98.2% similar) in 1460 aa overlap (1-1460:1-1433)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
       ::                           :::::::::::::::::::::::::::::::
XP_016 TT---------------------------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS
                                        1210      1220      1230   

             1270      1280      1290      1300      1310      1320
pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK
          1240      1250      1260      1270      1280      1290   

             1330      1340      1350      1360      1370      1380
pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN
          1300      1310      1320      1330      1340      1350   

             1390      1400      1410      1420      1430      1440
pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF
          1360      1370      1380      1390      1400      1410   

             1450      1460
pF1KSD SIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::
XP_016 SIHFNRFNPDGEEEDVTVQE
          1420      1430   

>>XP_016858434 (OMIM: 613023) PREDICTED: centrosomal pro  (1469 aa)
 initn: 9209 init1: 7242 opt: 7242  Z-score: 4937.8  bits: 926.3 E(85289):    0
Smith-Waterman score: 9090; 95.7% identity (95.8% similar) in 1496 aa overlap (1-1460:1-1469)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120                    
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA
             1090      1100      1110      1120      1130      1140

                             1130      1140      1150      1160    
pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
                              :::::::::::::::::::::::::::::::::::::
XP_016 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
             1150      1160      1170      1180      1190      1200

         1170      1180      1190      1200      1210      1220    
pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
       ::::::::::::::::::::::::::::::::::::::                      
XP_016 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTT----------------------
             1210      1220      1230                              

         1230      1240      1250      1260      1270      1280    
pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -----LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
          1240      1250      1260      1270      1280      1290   

         1290      1300      1310      1320      1330      1340    
pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
          1300      1310      1320      1330      1340      1350   

         1350      1360      1370      1380      1390      1400    
pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
          1360      1370      1380      1390      1400      1410   

         1410      1420      1430      1440      1450      1460
pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
          1420      1430      1440      1450      1460         

>>NP_001035863 (OMIM: 613023) centrosomal protein of 170  (1486 aa)
 initn: 8757 init1: 7242 opt: 7242  Z-score: 4937.8  bits: 926.3 E(85289):    0
Smith-Waterman score: 9224; 96.9% identity (96.9% similar) in 1496 aa overlap (1-1460:1-1486)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120                    
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
NP_001 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA
             1090      1100      1110      1120      1130      1140

                             1130      1140      1150      1160    
pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
                              :::::::::::::::::::::::::::::::::::::
NP_001 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
             1150      1160      1170      1180      1190      1200

         1170      1180      1190      1200      1210      1220    
pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREE-----
             1210      1220      1230      1240      1250          

         1230      1240      1250      1260      1270      1280    
pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
             1260      1270      1280      1290      1300      1310

         1290      1300      1310      1320      1330      1340    
pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
             1320      1330      1340      1350      1360      1370

         1350      1360      1370      1380      1390      1400    
pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
             1380      1390      1400      1410      1420      1430

         1410      1420      1430      1440      1450      1460
pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
             1440      1450      1460      1470      1480      

>>XP_011542646 (OMIM: 613023) PREDICTED: centrosomal pro  (1496 aa)
 initn: 7242 init1: 7242 opt: 7242  Z-score: 4937.7  bits: 926.3 E(85289):    0
Smith-Waterman score: 9304; 97.5% identity (97.6% similar) in 1492 aa overlap (1-1456:1-1492)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120                    
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_011 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA
             1090      1100      1110      1120      1130      1140

                             1130      1140      1150      1160    
pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
                              :::::::::::::::::::::::::::::::::::::
XP_011 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
             1150      1160      1170      1180      1190      1200

         1170      1180      1190      1200      1210      1220    
pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
             1210      1220      1230      1240      1250      1260

         1230      1240      1250      1260      1270      1280    
pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
             1270      1280      1290      1300      1310      1320

         1290      1300      1310      1320      1330      1340    
pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
             1330      1340      1350      1360      1370      1380

         1350      1360      1370      1380      1390      1400    
pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
             1390      1400      1410      1420      1430      1440

         1410      1420      1430      1440      1450      1460
pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
             1450      1460      1470      1480      1490      

>>XP_016858433 (OMIM: 613023) PREDICTED: centrosomal pro  (1496 aa)
 initn: 7242 init1: 7242 opt: 7242  Z-score: 4937.7  bits: 926.3 E(85289):    0
Smith-Waterman score: 9304; 97.5% identity (97.6% similar) in 1492 aa overlap (1-1456:1-1492)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120                    
pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA
             1090      1100      1110      1120      1130      1140

                             1130      1140      1150      1160    
pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
                              :::::::::::::::::::::::::::::::::::::
XP_016 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
             1150      1160      1170      1180      1190      1200

         1170      1180      1190      1200      1210      1220    
pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH
             1210      1220      1230      1240      1250      1260

         1230      1240      1250      1260      1270      1280    
pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
             1270      1280      1290      1300      1310      1320

         1290      1300      1310      1320      1330      1340    
pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
             1330      1340      1350      1360      1370      1380

         1350      1360      1370      1380      1390      1400    
pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
             1390      1400      1410      1420      1430      1440

         1410      1420      1430      1440      1450      1460
pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
             1450      1460      1470      1480      1490      

>>XP_016858430 (OMIM: 613023) PREDICTED: centrosomal pro  (1558 aa)
 initn: 9395 init1: 6609 opt: 6619  Z-score: 4513.4  bits: 847.8 E(85289):    0
Smith-Waterman score: 8764; 93.4% identity (93.4% similar) in 1492 aa overlap (67-1460:67-1558)

         40        50        60        70        80        90      
pF1KSD RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF
                                     ::::::::::::::::::::::::::::::
XP_016 RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF
         40        50        60        70        80        90      

        100       110       120       130       140       150      
pF1KSD TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE
        100       110       120       130       140       150      

        160       170       180       190       200       210      
pF1KSD ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_016 ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDA
        160       170       180       190       200       210      

        220       230       240       250       260       270      
pF1KSD KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG
        220       230       240       250       260       270      

        280       290       300       310       320       330      
pF1KSD HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW
        280       290       300       310       320       330      

        340       350       360       370       380       390      
pF1KSD LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL
        340       350       360       370       380       390      

        400       410       420                                    
pF1KSD EEHLRRHHSEHKKLQKVQATEKHQDQAV--------------------------------
       ::::::::::::::::::::::::::::                                
XP_016 EEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFL
        400       410       420       430       440       450      

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEA
        460       470       480       490       500       510      

                430       440       450       460       470        
pF1KSD ------VFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS
        520       530       540       550       560       570      

      480       490       500       510       520       530        
pF1KSD SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS
        580       590       600       610       620       630      

      540       550       560       570       580       590        
pF1KSD QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR
        640       650       660       670       680       690      

      600       610       620       630       640       650        
pF1KSD PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE
        700       710       720       730       740       750      

      660       670       680       690       700       710        
pF1KSD AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL
        760       770       780       790       800       810      

      720       730       740       750       760       770        
pF1KSD KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR
        820       830       840       850       860       870      

      780       790       800       810       820       830        
pF1KSD ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD
        880       890       900       910       920       930      

      840       850       860       870       880       890        
pF1KSD TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS
        940       950       960       970       980       990      

      900       910       920       930       940       950        
pF1KSD TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP
       1000      1010      1020      1030      1040      1050      

      960       970       980       990      1000      1010        
pF1KSD LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL
       1060      1070      1080      1090      1100      1110      

     1020      1030      1040      1050      1060      1070        
pF1KSD ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA
       1120      1130      1140      1150      1160      1170      

     1080      1090      1100      1110      1120      1130        
pF1KSD SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG
       1180      1190      1200      1210      1220      1230      

     1140      1150      1160      1170      1180      1190        
pF1KSD SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA
       1240      1250      1260      1270      1280      1290      

     1200      1210      1220      1230      1240      1250        
pF1KSD PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG
       1300      1310      1320      1330      1340      1350      

     1260      1270      1280      1290      1300      1310        
pF1KSD RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL
       1360      1370      1380      1390      1400      1410      

     1320      1330      1340      1350      1360      1370        
pF1KSD FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA
       1420      1430      1440      1450      1460      1470      

     1380      1390      1400      1410      1420      1430        
pF1KSD LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA
       1480      1490      1500      1510      1520      1530      

     1440      1450      1460
pF1KSD DFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::
XP_016 DFSIHFNRFNPDGEEEDVTVQE
       1540      1550        

>--
 initn: 439 init1: 439 opt: 439  Z-score: 307.5  bits: 69.6 E(85289): 2.2e-10
Smith-Waterman score: 439; 100.0% identity (100.0% similar) in 66 aa overlap (1-66:1-66)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::                                                      
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120

>>XP_016858426 (OMIM: 613023) PREDICTED: centrosomal pro  (1558 aa)
 initn: 9395 init1: 6609 opt: 6619  Z-score: 4513.4  bits: 847.8 E(85289):    0
Smith-Waterman score: 8764; 93.4% identity (93.4% similar) in 1492 aa overlap (67-1460:67-1558)

         40        50        60        70        80        90      
pF1KSD RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF
                                     ::::::::::::::::::::::::::::::
XP_016 RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF
         40        50        60        70        80        90      

        100       110       120       130       140       150      
pF1KSD TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE
        100       110       120       130       140       150      

        160       170       180       190       200       210      
pF1KSD ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_016 ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDA
        160       170       180       190       200       210      

        220       230       240       250       260       270      
pF1KSD KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG
        220       230       240       250       260       270      

        280       290       300       310       320       330      
pF1KSD HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW
        280       290       300       310       320       330      

        340       350       360       370       380       390      
pF1KSD LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL
        340       350       360       370       380       390      

        400       410       420                                    
pF1KSD EEHLRRHHSEHKKLQKVQATEKHQDQAV--------------------------------
       ::::::::::::::::::::::::::::                                
XP_016 EEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFL
        400       410       420       430       440       450      

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEA
        460       470       480       490       500       510      

                430       440       450       460       470        
pF1KSD ------VFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS
        520       530       540       550       560       570      

      480       490       500       510       520       530        
pF1KSD SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS
        580       590       600       610       620       630      

      540       550       560       570       580       590        
pF1KSD QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR
        640       650       660       670       680       690      

      600       610       620       630       640       650        
pF1KSD PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE
        700       710       720       730       740       750      

      660       670       680       690       700       710        
pF1KSD AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL
        760       770       780       790       800       810      

      720       730       740       750       760       770        
pF1KSD KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR
        820       830       840       850       860       870      

      780       790       800       810       820       830        
pF1KSD ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD
        880       890       900       910       920       930      

      840       850       860       870       880       890        
pF1KSD TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS
        940       950       960       970       980       990      

      900       910       920       930       940       950        
pF1KSD TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP
       1000      1010      1020      1030      1040      1050      

      960       970       980       990      1000      1010        
pF1KSD LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL
       1060      1070      1080      1090      1100      1110      

     1020      1030      1040      1050      1060      1070        
pF1KSD ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA
       1120      1130      1140      1150      1160      1170      

     1080      1090      1100      1110      1120      1130        
pF1KSD SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG
       1180      1190      1200      1210      1220      1230      

     1140      1150      1160      1170      1180      1190        
pF1KSD SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA
       1240      1250      1260      1270      1280      1290      

     1200      1210      1220      1230      1240      1250        
pF1KSD PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG
       1300      1310      1320      1330      1340      1350      

     1260      1270      1280      1290      1300      1310        
pF1KSD RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL
       1360      1370      1380      1390      1400      1410      

     1320      1330      1340      1350      1360      1370        
pF1KSD FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA
       1420      1430      1440      1450      1460      1470      

     1380      1390      1400      1410      1420      1430        
pF1KSD LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA
       1480      1490      1500      1510      1520      1530      

     1440      1450      1460
pF1KSD DFSIHFNRFNPDGEEEDVTVQE
       ::::::::::::::::::::::
XP_016 DFSIHFNRFNPDGEEEDVTVQE
       1540      1550        

>--
 initn: 439 init1: 439 opt: 439  Z-score: 307.5  bits: 69.6 E(85289): 2.2e-10
Smith-Waterman score: 439; 100.0% identity (100.0% similar) in 66 aa overlap (1-66:1-66)

               10        20        30        40        50        60
pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
       ::::::                                                      
XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
               70        80        90       100       110       120




1460 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:50:27 2016 done: Thu Nov  3 01:50:29 2016
 Total Scan time: 14.500 Total Display time:  0.810

Function used was FASTA [36.3.4 Apr, 2011]
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