FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0470, 1460 aa 1>>>pF1KSDA0470 1460 - 1460 aa - 1460 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3532+/-0.00046; mu= -1.9460+/- 0.028 mean_var=215.8966+/-44.114, 0's: 0 Z-trim(115.7): 120 B-trim: 167 in 1/60 Lambda= 0.087287 statistics sampled from 26228 (26349) to 26228 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.309), width: 16 Scan time: 14.500 The best scores are: opt bits E(85289) NP_001035864 (OMIM: 613023) centrosomal protein of (1460) 9409 1199.2 0 XP_016858437 (OMIM: 613023) PREDICTED: centrosomal (1450) 7813 998.2 0 XP_016858436 (OMIM: 613023) PREDICTED: centrosomal (1450) 7813 998.2 0 XP_016858438 (OMIM: 613023) PREDICTED: centrosomal (1433) 7709 985.1 0 XP_016858434 (OMIM: 613023) PREDICTED: centrosomal (1469) 7242 926.3 0 NP_001035863 (OMIM: 613023) centrosomal protein of (1486) 7242 926.3 0 XP_011542646 (OMIM: 613023) PREDICTED: centrosomal (1496) 7242 926.3 0 XP_016858433 (OMIM: 613023) PREDICTED: centrosomal (1496) 7242 926.3 0 XP_016858430 (OMIM: 613023) PREDICTED: centrosomal (1558) 6619 847.8 0 XP_016858426 (OMIM: 613023) PREDICTED: centrosomal (1558) 6619 847.8 0 XP_011542641 (OMIM: 613023) PREDICTED: centrosomal (1620) 6617 847.6 0 XP_011542645 (OMIM: 613023) PREDICTED: centrosomal (1497) 5780 742.2 7.2e-213 XP_016858427 (OMIM: 613023) PREDICTED: centrosomal (1548) 5023 646.8 3.7e-184 XP_011542642 (OMIM: 613023) PREDICTED: centrosomal (1610) 5021 646.6 4.5e-184 XP_016858432 (OMIM: 613023) PREDICTED: centrosomal (1531) 4919 633.7 3.2e-180 XP_016858431 (OMIM: 613023) PREDICTED: centrosomal (1531) 4919 633.7 3.2e-180 XP_011542644 (OMIM: 613023) PREDICTED: centrosomal (1593) 4917 633.5 3.9e-180 XP_016858440 (OMIM: 613023) PREDICTED: centrosomal (1337) 4818 621.0 1.9e-176 XP_016858439 (OMIM: 613023) PREDICTED: centrosomal (1408) 4465 576.6 4.8e-163 XP_016858435 (OMIM: 613023) PREDICTED: centrosomal (1435) 4465 576.6 4.9e-163 XP_016858429 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162 XP_016858424 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162 XP_016858428 (OMIM: 613023) PREDICTED: centrosomal (1567) 4452 574.9 1.6e-162 NP_055627 (OMIM: 613023) centrosomal protein of 17 (1584) 4452 574.9 1.7e-162 XP_016858425 (OMIM: 613023) PREDICTED: centrosomal (1584) 4452 574.9 1.7e-162 XP_016858423 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162 XP_016858422 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162 XP_011542643 (OMIM: 613023) PREDICTED: centrosomal (1594) 4452 574.9 1.7e-162 XP_011542640 (OMIM: 613023) PREDICTED: centrosomal (1629) 4450 574.7 2e-162 XP_011542639 (OMIM: 613023) PREDICTED: centrosomal (1646) 4450 574.7 2e-162 XP_011542637 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162 XP_011542638 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162 XP_011542636 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162 XP_006711906 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162 XP_016858421 (OMIM: 613023) PREDICTED: centrosomal (1656) 4450 574.7 2.1e-162 >>NP_001035864 (OMIM: 613023) centrosomal protein of 170 (1460 aa) initn: 9409 init1: 9409 opt: 9409 Z-score: 6412.7 bits: 1199.2 E(85289): 0 Smith-Waterman score: 9409; 99.9% identity (100.0% similar) in 1460 aa overlap (1-1460:1-1460) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: NP_001 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF 1390 1400 1410 1420 1430 1440 1450 1460 pF1KSD SIHFNRFNPDGEEEDVTVQE :::::::::::::::::::: NP_001 SIHFNRFNPDGEEEDVTVQE 1450 1460 >>XP_016858437 (OMIM: 613023) PREDICTED: centrosomal pro (1450 aa) initn: 7813 init1: 7813 opt: 7813 Z-score: 5326.5 bits: 998.2 E(85289): 0 Smith-Waterman score: 9306; 99.2% identity (99.3% similar) in 1460 aa overlap (1-1460:1-1450) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS ::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_016 TTVSTAATTPGSAIDTREE----------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF 1380 1390 1400 1410 1420 1430 1450 1460 pF1KSD SIHFNRFNPDGEEEDVTVQE :::::::::::::::::::: XP_016 SIHFNRFNPDGEEEDVTVQE 1440 1450 >>XP_016858436 (OMIM: 613023) PREDICTED: centrosomal pro (1450 aa) initn: 7813 init1: 7813 opt: 7813 Z-score: 5326.5 bits: 998.2 E(85289): 0 Smith-Waterman score: 9306; 99.2% identity (99.3% similar) in 1460 aa overlap (1-1460:1-1450) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS ::::::::::::::::::: ::::::::::::::::::::::::::::::: XP_016 TTVSTAATTPGSAIDTREE----------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF 1380 1390 1400 1410 1420 1430 1450 1460 pF1KSD SIHFNRFNPDGEEEDVTVQE :::::::::::::::::::: XP_016 SIHFNRFNPDGEEEDVTVQE 1440 1450 >>XP_016858438 (OMIM: 613023) PREDICTED: centrosomal pro (1433 aa) initn: 7743 init1: 7709 opt: 7709 Z-score: 5255.8 bits: 985.1 E(85289): 0 Smith-Waterman score: 9172; 98.1% identity (98.2% similar) in 1460 aa overlap (1-1460:1-1433) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRS :: ::::::::::::::::::::::::::::::: XP_016 TT---------------------------LVDRVFDESLNFRKIPPLVHSKTPEGNNGRS 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KSD GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFK 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KSD DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KSD NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADF 1360 1370 1380 1390 1400 1410 1450 1460 pF1KSD SIHFNRFNPDGEEEDVTVQE :::::::::::::::::::: XP_016 SIHFNRFNPDGEEEDVTVQE 1420 1430 >>XP_016858434 (OMIM: 613023) PREDICTED: centrosomal pro (1469 aa) initn: 9209 init1: 7242 opt: 7242 Z-score: 4937.8 bits: 926.3 E(85289): 0 Smith-Waterman score: 9090; 95.7% identity (95.8% similar) in 1496 aa overlap (1-1460:1-1469) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH ::::::::::::::::::::::::::::::::::::: XP_016 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH :::::::::::::::::::::::::::::::::::::: XP_016 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTT---------------------- 1210 1220 1230 1230 1240 1250 1260 1270 1280 pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1240 1250 1260 1270 1280 1290 1290 1300 1310 1320 1330 1340 pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1300 1310 1320 1330 1340 1350 1350 1360 1370 1380 1390 1400 pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1360 1370 1380 1390 1400 1410 1410 1420 1430 1440 1450 1460 pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1420 1430 1440 1450 1460 >>NP_001035863 (OMIM: 613023) centrosomal protein of 170 (1486 aa) initn: 8757 init1: 7242 opt: 7242 Z-score: 4937.8 bits: 926.3 E(85289): 0 Smith-Waterman score: 9224; 96.9% identity (96.9% similar) in 1496 aa overlap (1-1460:1-1486) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: NP_001 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS------------- ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH ::::::::::::::::::::::::::::::::::::: NP_001 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREE----- 1210 1220 1230 1240 1250 1230 1240 1250 1260 1270 1280 pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1260 1270 1280 1290 1300 1310 1290 1300 1310 1320 1330 1340 pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1320 1330 1340 1350 1360 1370 1350 1360 1370 1380 1390 1400 pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1380 1390 1400 1410 1420 1430 1410 1420 1430 1440 1450 1460 pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1440 1450 1460 1470 1480 >>XP_011542646 (OMIM: 613023) PREDICTED: centrosomal pro (1496 aa) initn: 7242 init1: 7242 opt: 7242 Z-score: 4937.7 bits: 926.3 E(85289): 0 Smith-Waterman score: 9304; 97.5% identity (97.6% similar) in 1492 aa overlap (1-1456:1-1492) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_011 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH ::::::::::::::::::::::::::::::::::::: XP_011 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1450 1460 1470 1480 1490 >>XP_016858433 (OMIM: 613023) PREDICTED: centrosomal pro (1496 aa) initn: 7242 init1: 7242 opt: 7242 Z-score: 4937.7 bits: 926.3 E(85289): 0 Smith-Waterman score: 9304; 97.5% identity (97.6% similar) in 1492 aa overlap (1-1456:1-1492) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDAKQVEEQSAAANEEVLFPFCREPSY ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 pF1KSD -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH ::::::::::::::::::::::::::::::::::::: XP_016 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1450 1460 1470 1480 1490 >>XP_016858430 (OMIM: 613023) PREDICTED: centrosomal pro (1558 aa) initn: 9395 init1: 6609 opt: 6619 Z-score: 4513.4 bits: 847.8 E(85289): 0 Smith-Waterman score: 8764; 93.4% identity (93.4% similar) in 1492 aa overlap (67-1460:67-1558) 40 50 60 70 80 90 pF1KSD RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF :::::::::::::::::::::::::::::: XP_016 RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF 40 50 60 70 80 90 100 110 120 130 140 150 pF1KSD TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE 100 110 120 130 140 150 160 170 180 190 200 210 pF1KSD ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_016 ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDA 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG 220 230 240 250 260 270 280 290 300 310 320 330 pF1KSD HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW 280 290 300 310 320 330 340 350 360 370 380 390 pF1KSD LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL 340 350 360 370 380 390 400 410 420 pF1KSD EEHLRRHHSEHKKLQKVQATEKHQDQAV-------------------------------- :::::::::::::::::::::::::::: XP_016 EEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFL 400 410 420 430 440 450 pF1KSD ------------------------------------------------------------ XP_016 QTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEA 460 470 480 490 500 510 430 440 450 460 470 pF1KSD ------VFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS 520 530 540 550 560 570 480 490 500 510 520 530 pF1KSD SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS 580 590 600 610 620 630 540 550 560 570 580 590 pF1KSD QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR 640 650 660 670 680 690 600 610 620 630 640 650 pF1KSD PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE 700 710 720 730 740 750 660 670 680 690 700 710 pF1KSD AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL 760 770 780 790 800 810 720 730 740 750 760 770 pF1KSD KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR 820 830 840 850 860 870 780 790 800 810 820 830 pF1KSD ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD 880 890 900 910 920 930 840 850 860 870 880 890 pF1KSD TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS 940 950 960 970 980 990 900 910 920 930 940 950 pF1KSD TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP 1000 1010 1020 1030 1040 1050 960 970 980 990 1000 1010 pF1KSD LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL 1060 1070 1080 1090 1100 1110 1020 1030 1040 1050 1060 1070 pF1KSD ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA 1120 1130 1140 1150 1160 1170 1080 1090 1100 1110 1120 1130 pF1KSD SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG 1180 1190 1200 1210 1220 1230 1140 1150 1160 1170 1180 1190 pF1KSD SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA 1240 1250 1260 1270 1280 1290 1200 1210 1220 1230 1240 1250 pF1KSD PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG 1300 1310 1320 1330 1340 1350 1260 1270 1280 1290 1300 1310 pF1KSD RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL 1360 1370 1380 1390 1400 1410 1320 1330 1340 1350 1360 1370 pF1KSD FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA 1420 1430 1440 1450 1460 1470 1380 1390 1400 1410 1420 1430 pF1KSD LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA 1480 1490 1500 1510 1520 1530 1440 1450 1460 pF1KSD DFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::: XP_016 DFSIHFNRFNPDGEEEDVTVQE 1540 1550 >-- initn: 439 init1: 439 opt: 439 Z-score: 307.5 bits: 69.6 E(85289): 2.2e-10 Smith-Waterman score: 439; 100.0% identity (100.0% similar) in 66 aa overlap (1-66:1-66) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 >>XP_016858426 (OMIM: 613023) PREDICTED: centrosomal pro (1558 aa) initn: 9395 init1: 6609 opt: 6619 Z-score: 4513.4 bits: 847.8 E(85289): 0 Smith-Waterman score: 8764; 93.4% identity (93.4% similar) in 1492 aa overlap (67-1460:67-1558) 40 50 60 70 80 90 pF1KSD RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF :::::::::::::::::::::::::::::: XP_016 RSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLF 40 50 60 70 80 90 100 110 120 130 140 150 pF1KSD TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTE 100 110 120 130 140 150 160 170 180 190 200 210 pF1KSD ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCSIDA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_016 ALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDA 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAG 220 230 240 250 260 270 280 290 300 310 320 330 pF1KSD HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADW 280 290 300 310 320 330 340 350 360 370 380 390 pF1KSD LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATL 340 350 360 370 380 390 400 410 420 pF1KSD EEHLRRHHSEHKKLQKVQATEKHQDQAV-------------------------------- :::::::::::::::::::::::::::: XP_016 EEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFL 400 410 420 430 440 450 pF1KSD ------------------------------------------------------------ XP_016 QTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEA 460 470 480 490 500 510 430 440 450 460 470 pF1KSD ------VFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTS 520 530 540 550 560 570 480 490 500 510 520 530 pF1KSD SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS 580 590 600 610 620 630 540 550 560 570 580 590 pF1KSD QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR 640 650 660 670 680 690 600 610 620 630 640 650 pF1KSD PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREE 700 710 720 730 740 750 660 670 680 690 700 710 pF1KSD AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEIL 760 770 780 790 800 810 720 730 740 750 760 770 pF1KSD KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIR 820 830 840 850 860 870 780 790 800 810 820 830 pF1KSD ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVD 880 890 900 910 920 930 840 850 860 870 880 890 pF1KSD TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRS 940 950 960 970 980 990 900 910 920 930 940 950 pF1KSD TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTP 1000 1010 1020 1030 1040 1050 960 970 980 990 1000 1010 pF1KSD LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL 1060 1070 1080 1090 1100 1110 1020 1030 1040 1050 1060 1070 pF1KSD ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSA 1120 1130 1140 1150 1160 1170 1080 1090 1100 1110 1120 1130 pF1KSD SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAG 1180 1190 1200 1210 1220 1230 1140 1150 1160 1170 1180 1190 pF1KSD SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTA 1240 1250 1260 1270 1280 1290 1200 1210 1220 1230 1240 1250 pF1KSD PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNG 1300 1310 1320 1330 1340 1350 1260 1270 1280 1290 1300 1310 pF1KSD RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRIL 1360 1370 1380 1390 1400 1410 1320 1330 1340 1350 1360 1370 pF1KSD FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEA 1420 1430 1440 1450 1460 1470 1380 1390 1400 1410 1420 1430 pF1KSD LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEA 1480 1490 1500 1510 1520 1530 1440 1450 1460 pF1KSD DFSIHFNRFNPDGEEEDVTVQE :::::::::::::::::::::: XP_016 DFSIHFNRFNPDGEEEDVTVQE 1540 1550 >-- initn: 439 init1: 439 opt: 439 Z-score: 307.5 bits: 69.6 E(85289): 2.2e-10 Smith-Waterman score: 439; 100.0% identity (100.0% similar) in 66 aa overlap (1-66:1-66) 10 20 30 40 50 60 pF1KSD MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ :::::: XP_016 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 70 80 90 100 110 120 1460 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:50:27 2016 done: Thu Nov 3 01:50:29 2016 Total Scan time: 14.500 Total Display time: 0.810 Function used was FASTA [36.3.4 Apr, 2011]