FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0478, 1239 aa 1>>>pF1KSDA0478 1239 - 1239 aa - 1239 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3588+/-0.000646; mu= 5.6681+/- 0.040 mean_var=497.4911+/-109.304, 0's: 0 Z-trim(115.9): 1578 B-trim: 117 in 1/55 Lambda= 0.057502 statistics sampled from 24751 (26683) to 24751 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.313), width: 16 Scan time: 14.350 The best scores are: opt bits E(85289) XP_011540801 (OMIM: 612106) PREDICTED: zinc finger (1239) 8237 700.4 1.9e-200 NP_001077090 (OMIM: 612106) zinc finger and BTB do (1239) 8237 700.4 1.9e-200 NP_055685 (OMIM: 612106) zinc finger and BTB domai (1239) 8237 700.4 1.9e-200 NP_001317327 (OMIM: 612106) zinc finger and BTB do (1127) 5783 496.7 3.5e-139 XP_011540802 (OMIM: 612106) PREDICTED: zinc finger ( 662) 4365 378.8 6.7e-104 XP_006722936 (OMIM: 194543) PREDICTED: zinc finger ( 569) 658 71.1 2.3e-11 NP_056936 (OMIM: 194624) zinc finger protein 117 [ ( 483) 653 70.6 2.8e-11 XP_016881641 (OMIM: 604750) PREDICTED: zinc finger ( 502) 651 70.5 3.3e-11 XP_016881642 (OMIM: 604750) PREDICTED: zinc finger ( 502) 651 70.5 3.3e-11 NP_001273627 (OMIM: 194552) zinc finger protein 79 ( 364) 647 69.9 3.5e-11 XP_016881640 (OMIM: 604750) PREDICTED: zinc finger ( 669) 651 70.7 3.8e-11 XP_016881639 (OMIM: 604750) PREDICTED: zinc finger ( 688) 651 70.7 3.9e-11 XP_006723037 (OMIM: 604750) PREDICTED: zinc finger ( 700) 651 70.7 3.9e-11 XP_016881638 (OMIM: 604750) PREDICTED: zinc finger ( 700) 651 70.7 3.9e-11 NP_006621 (OMIM: 604750) zinc finger protein 234 [ ( 700) 651 70.7 3.9e-11 NP_001138296 (OMIM: 604750) zinc finger protein 23 ( 700) 651 70.7 3.9e-11 NP_001273625 (OMIM: 194552) zinc finger protein 79 ( 474) 647 70.1 4e-11 XP_006717342 (OMIM: 194552) PREDICTED: zinc finger ( 474) 647 70.1 4e-11 NP_001309189 (OMIM: 194552) zinc finger protein 79 ( 474) 647 70.1 4e-11 NP_001273626 (OMIM: 194552) zinc finger protein 79 ( 474) 647 70.1 4e-11 NP_009066 (OMIM: 194552) zinc finger protein 79 is ( 498) 647 70.1 4.1e-11 XP_016882723 (OMIM: 603899) PREDICTED: zinc finger ( 518) 647 70.2 4.2e-11 NP_001243102 (OMIM: 603899) zinc finger protein 85 ( 531) 647 70.2 4.2e-11 XP_011526566 (OMIM: 603899) PREDICTED: zinc finger ( 536) 647 70.2 4.3e-11 NP_003420 (OMIM: 603899) zinc finger protein 85 is ( 595) 647 70.2 4.5e-11 NP_001243100 (OMIM: 603899) zinc finger protein 85 ( 625) 647 70.3 4.6e-11 XP_011526565 (OMIM: 603899) PREDICTED: zinc finger ( 640) 647 70.3 4.7e-11 XP_016873753 (OMIM: 602187) PREDICTED: zinc finger ( 489) 644 69.9 4.8e-11 NP_001177720 (OMIM: 613864) zinc finger protein 31 ( 563) 645 70.0 4.9e-11 XP_016873754 (OMIM: 602187) PREDICTED: zinc finger ( 530) 644 69.9 5e-11 XP_016873755 (OMIM: 602187) PREDICTED: zinc finger ( 530) 644 69.9 5e-11 NP_065984 (OMIM: 613864) zinc finger protein 317 i ( 595) 645 70.1 5e-11 XP_016873756 (OMIM: 602187) PREDICTED: zinc finger ( 553) 644 69.9 5.1e-11 NP_009083 (OMIM: 602187) zinc finger protein 195 i ( 557) 644 70.0 5.2e-11 NP_001229772 (OMIM: 602187) zinc finger protein 19 ( 561) 644 70.0 5.2e-11 NP_001243754 (OMIM: 602187) zinc finger protein 19 ( 561) 644 70.0 5.2e-11 XP_006718369 (OMIM: 602187) PREDICTED: zinc finger ( 572) 644 70.0 5.2e-11 NP_001229771 (OMIM: 602187) zinc finger protein 19 ( 584) 644 70.0 5.3e-11 NP_001243753 (OMIM: 602187) zinc finger protein 19 ( 592) 644 70.0 5.3e-11 XP_011518654 (OMIM: 602187) PREDICTED: zinc finger ( 595) 644 70.0 5.3e-11 NP_001123991 (OMIM: 602187) zinc finger protein 19 ( 606) 644 70.0 5.4e-11 XP_016873752 (OMIM: 602187) PREDICTED: zinc finger ( 610) 644 70.0 5.4e-11 NP_001229770 (OMIM: 602187) zinc finger protein 19 ( 610) 644 70.0 5.4e-11 XP_016873751 (OMIM: 602187) PREDICTED: zinc finger ( 621) 644 70.0 5.5e-11 NP_001123992 (OMIM: 602187) zinc finger protein 19 ( 629) 644 70.0 5.5e-11 XP_016873750 (OMIM: 602187) PREDICTED: zinc finger ( 633) 644 70.0 5.5e-11 XP_011518652 (OMIM: 602187) PREDICTED: zinc finger ( 633) 644 70.0 5.5e-11 XP_011518653 (OMIM: 602187) PREDICTED: zinc finger ( 633) 644 70.0 5.5e-11 XP_016873749 (OMIM: 602187) PREDICTED: zinc finger ( 644) 644 70.0 5.6e-11 NP_001243583 (OMIM: 603972) zinc finger protein 43 ( 744) 644 70.1 6e-11 >>XP_011540801 (OMIM: 612106) PREDICTED: zinc finger and (1239 aa) initn: 8237 init1: 8237 opt: 8237 Z-score: 3719.6 bits: 700.4 E(85289): 1.9e-200 Smith-Waterman score: 8237; 99.8% identity (99.8% similar) in 1239 aa overlap (1-1239:1-1239) 10 20 30 40 50 60 pF1KSD MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPPVQTFSEAKKTSTEPGCERKHYQ ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_011 SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIECKLFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_011 TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK ::::::::::::::::::::::::::::::::::::::: XP_011 QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK 1210 1220 1230 >>NP_001077090 (OMIM: 612106) zinc finger and BTB domain (1239 aa) initn: 8237 init1: 8237 opt: 8237 Z-score: 3719.6 bits: 700.4 E(85289): 1.9e-200 Smith-Waterman score: 8237; 99.8% identity (99.8% similar) in 1239 aa overlap (1-1239:1-1239) 10 20 30 40 50 60 pF1KSD MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPPVQTFSEAKKTSTEPGCERKHYQ ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIECKLFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK ::::::::::::::::::::::::::::::::::::::: NP_001 QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK 1210 1220 1230 >>NP_055685 (OMIM: 612106) zinc finger and BTB domain-co (1239 aa) initn: 8237 init1: 8237 opt: 8237 Z-score: 3719.6 bits: 700.4 E(85289): 1.9e-200 Smith-Waterman score: 8237; 99.8% identity (99.8% similar) in 1239 aa overlap (1-1239:1-1239) 10 20 30 40 50 60 pF1KSD MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPPVQTFSEAKKTSTEPGCERKHYQ ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_055 SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIECKLFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_055 ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_055 TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK ::::::::::::::::::::::::::::::::::::::: NP_055 QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK 1210 1220 1230 >>NP_001317327 (OMIM: 612106) zinc finger and BTB domain (1127 aa) initn: 5764 init1: 5764 opt: 5783 Z-score: 2619.8 bits: 496.7 E(85289): 3.5e-139 Smith-Waterman score: 7293; 90.7% identity (90.8% similar) in 1239 aa overlap (1-1239:1-1127) 10 20 30 40 50 60 pF1KSD MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPPVQTFSEAKKTSTEPGCERKHYQ ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR ::::::::::::::::::::::::::::::::::::: NP_001 LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKE----------------------- 250 260 270 310 320 330 340 350 360 pF1KSD EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED NP_001 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KSD LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE ::::::::::::::::::::::::::::::: NP_001 -----------------------------VILNCCEGRTPKETIENLLHRMTEEKTLTAE 280 290 300 430 440 450 460 470 480 pF1KSD GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN 310 320 330 340 350 360 490 500 510 520 530 540 pF1KSD QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ 370 380 390 400 410 420 550 560 570 580 590 600 pF1KSD ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIECKLFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_001 ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTS 430 440 450 460 470 480 610 620 630 640 650 660 pF1KSD EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV 490 500 510 520 530 540 670 680 690 700 710 720 pF1KSD MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ 550 560 570 580 590 600 730 740 750 760 770 780 pF1KSD QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE 610 620 630 640 650 660 790 800 810 820 830 840 pF1KSD LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE 670 680 690 700 710 720 850 860 870 880 890 900 pF1KSD CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA 730 740 750 760 770 780 910 920 930 940 950 960 pF1KSD VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP 790 800 810 820 830 840 970 980 990 1000 1010 1020 pF1KSD TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSG ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSG 850 860 870 880 890 900 1030 1040 1050 1060 1070 1080 pF1KSD LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC 910 920 930 940 950 960 1090 1100 1110 1120 1130 1140 pF1KSD KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC 970 980 990 1000 1010 1020 1150 1160 1170 1180 1190 1200 pF1KSD GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS 1030 1040 1050 1060 1070 1080 1210 1220 1230 pF1KSD QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK ::::::::::::::::::::::::::::::::::::::: NP_001 QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK 1090 1100 1110 1120 >>XP_011540802 (OMIM: 612106) PREDICTED: zinc finger and (662 aa) initn: 4365 init1: 4365 opt: 4365 Z-score: 1986.3 bits: 378.8 E(85289): 6.7e-104 Smith-Waterman score: 4370; 96.2% identity (97.1% similar) in 660 aa overlap (589-1239:3-662) 560 570 580 590 600 610 pF1KSD GADAFFRAVTTPEHATLETILRHNQLILEAIQQKIECKLFTSEEEH---LAETVK----- .: .: : : :.:. : : XP_011 MGVQPRIICILSGEEQERNMKLNYRFKCSALL 10 20 30 620 630 640 650 660 pF1KSD -EILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPVMQELAYIGV .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPVMQELAYIGV 40 50 60 70 80 90 670 680 690 700 710 720 pF1KSD LTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQQEKEASASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQQEKEASASP 100 110 120 130 140 150 730 740 750 760 770 780 pF1KSD DPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKELDKHQLEAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKELDKHQLEAH 160 170 180 190 200 210 790 800 810 820 830 840 pF1KSD GAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANS 220 230 240 250 260 270 850 860 870 880 890 900 pF1KSD TLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELS 280 290 300 310 320 330 910 920 930 940 950 960 pF1KSD RHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHI 340 350 360 370 380 390 970 980 990 1000 1010 1020 pF1KSD HEVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHH :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_011 HEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHH 400 410 420 430 440 450 1030 1040 1050 1060 1070 1080 pF1KSD PDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQCKELFPTPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQCKELFPTPAL 460 470 480 490 500 510 1090 1100 1110 1120 1130 1140 pF1KSD LQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQ 520 530 540 550 560 570 1150 1160 1170 1180 1190 1200 pF1KSD LDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDS 580 590 600 610 620 630 1210 1220 1230 pF1KSD QASQASSELVAVTVEDLLDGTVTLICGEAK :::::::::::::::::::::::::::::: XP_011 QASQASSELVAVTVEDLLDGTVTLICGEAK 640 650 660 >>XP_006722936 (OMIM: 194543) PREDICTED: zinc finger pro (569 aa) initn: 898 init1: 220 opt: 658 Z-score: 324.9 bits: 71.1 E(85289): 2.3e-11 Smith-Waterman score: 817; 30.5% identity (54.7% similar) in 499 aa overlap (678-1158:68-531) 650 660 670 680 690 pF1KSD CSVHKSFPGLQPVMQELAYIGVLTKEDGEKETWKVSNKFHLEANNKED-----EKAA--- ..:: .: . : ... :: . XP_006 QEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEI 40 50 60 70 80 90 700 710 720 730 740 750 pF1KSD KEDSQPGEQNDQGETGSLPGQQEKEASASPD-PAKKSFICKAC---DKSFHFYCRLKVHM :.::. :: : : :..: :::. . ::.: ..::.. : . XP_006 KDDSHCGETFTQVPDDRLNFQEKK---ASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGH 100 110 120 130 140 150 760 770 780 790 800 810 pF1KSD KRCRVAKSKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGRE : . . :: :.. : . .. : . :. . .: : .: ::. XP_006 KAYEYQEYGPKPCK-CQQPKKA--------FRYHPSFRTPQRDHTGEK--PYACKECGKT 160 170 180 190 200 820 830 840 850 860 870 pF1KSD FAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQ : :..: : .. : . :..:. :: : : : :.:::..:. ::.: .:. XP_006 FISHSSIQRH-VVMHSGDGPYKCKFCGKAFHCLSLYLIHERIHTGEKPYECKQCGKSFSY 210 220 230 240 250 260 880 890 900 910 920 930 pF1KSD ASALAYHTKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANG ...: : .. :. : : :: : .: . :: : :::.: : :..:::.: . XP_006 SATLRIH-ERTHTGEKPYECQQCGKAFHSPRCYRRHERIHTGEKAYQCKECGKAFTCPQY 270 280 290 300 310 320 940 950 960 970 980 990 pF1KSD LSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHIHEVHSKEY-HPCPTCGKIFSAPSMLE . :: .: :. . ::.: .: .. .: . . ::. .:: : . : ::: : . . .. XP_006 VRIHERT-HSRKKPYECTQCGKALSSLTSFQTHIR-MHSGERPYECKICGKGFCSANSFQ 330 340 350 360 370 1000 1010 1020 1030 1040 1050 pF1KSD RHMVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKT :: :: : ::..: :.::. . :.: ::.: : . . .:..: :. XP_006 RHEKTHSGEKPYKCKQCGKAFIHSSSLRYHERIHTGE------------KPYECKQCGKA 380 390 400 410 420 1060 1070 1080 1090 1100 pF1KSD FPNTIEHKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQ-----HSGSQPFRCLYC : .. . . : .. :. : .::..: . : . :: : . : ::: .:..: : XP_006 FRSSSHLQLHGRT-HTGEKPYECQECGKAFRSMKNLQSHERTQTHVRIHSGERPYKCKLC 430 440 450 460 470 480 1110 1120 1130 1140 1150 1160 pF1KSD AATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLESEHPKVMSTETQAA . : : .::.: :. . .: . :. ::: :.:.... : : : XP_006 GKGFYCPKSLQRH---EKTHTGEKLYECKQCGEAFSSSSSFRYH-ERTHTGEKPYKCKQC 490 500 510 520 530 540 1170 1180 1190 1200 1210 1220 pF1KSD ASQMAQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDSQASQASSELVAVTVEDLLDG XP_006 GKAFRAASVLRMHGRTHPEDKPYECKQ 550 560 >>NP_056936 (OMIM: 194624) zinc finger protein 117 [Homo (483 aa) initn: 555 init1: 203 opt: 653 Z-score: 323.4 bits: 70.6 E(85289): 2.8e-11 Smith-Waterman score: 781; 32.7% identity (56.8% similar) in 428 aa overlap (734-1142:79-480) 710 720 730 740 750 760 pF1KSD QPGEQNDQGETGSLPGQQEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKS : : :. . :: . : . : ... NP_056 LRKGCKSVVECKQHKGDYSGLNQCLKTTLSKIFQCNKYVEVFHKISNSNRH--KMRHTEN 50 60 70 80 90 100 770 780 790 800 pF1KSD KQVQCKECSETKDSKKELDKHQ----------LEAHGAGGEPDAPKKKKKRL-----PVT :. .:::: .: ..: .:. ::.: . . .. .:.::. : NP_056 KHFKCKECRKTFCMLSHLTQHKRIQTRVNFYKCEAYGRAFNWSSTLNKHKRIHTGEKPYK 110 120 130 140 150 160 810 820 830 840 850 860 pF1KSD CDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKH : ::. : ..: . :: : .:::..::::: : .::: .: .:::. :. :.. NP_056 CKECGKAFNQTSHLIRHKRI-HTEEKPYKCEECGKAFNQSSTLTTHNIIHTGEIPYKCEK 170 180 190 200 210 220 870 880 890 900 910 920 pF1KSD CLMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGK :. .:.::: :. : : :. : : :. : .: .: .:..: :::.: : :..::: NP_056 CVRAFNQASKLTEH-KLIHTGEKRYECEECGKAFNRSSKLTEHKYIHTGEKLYKCEECGK 230 240 250 260 270 280 930 940 950 960 970 980 pF1KSD GFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP---TLQDHRKHIHEVHSKEY-HPCPTCG .: :.. :. : . .:. : :: :..: .: .: ::.: .:. : . : :: NP_056 AFNQSSTLTTH-KRIHSGEKPYKCEECGKAFKQFSNLTDHKK----IHTGEKPYKCEECG 290 300 310 320 330 990 1000 1010 1020 1030 1040 pF1KSD KIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFS : :. : : :: : :.: ::..:: :.::..: :.: :. : . . :. NP_056 KAFNQLSNLTRHKVIHTGEKPYKCGECGKAFNQSSALNTHKIIHTGE----NPHK----- 340 350 360 370 380 390 1050 1060 1070 1080 1090 1100 pF1KSD SLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQHSGSQPF : :.: . . . : :. :...:..: . : . : : : :.: .:. NP_056 ---CRESGKVF-HLSSKLSTCKKIHTGEKLYKCEECGKAFNRSSTLIGH-KRIHTGEKPY 400 410 420 430 440 1110 1120 1130 1140 1150 1160 pF1KSD RCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLESEHPKVMST .: :. .: ..: : . .. : . :. ::. NP_056 KCEECGKAFNQSSTLTTH---KIIHTEEKQYKCDECGKAST 450 460 470 480 1170 1180 1190 1200 1210 1220 pF1KSD ETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDSQASQASSELVAVTVE >>XP_016881641 (OMIM: 604750) PREDICTED: zinc finger pro (502 aa) initn: 486 init1: 201 opt: 651 Z-score: 322.3 bits: 70.5 E(85289): 3.3e-11 Smith-Waterman score: 831; 32.1% identity (55.2% similar) in 458 aa overlap (733-1181:3-423) 710 720 730 740 750 760 pF1KSD SQPGEQNDQGETGSLPGQQEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAK .: . : .: : : .:..:.. : : XP_016 MGEKCYKCDVCGKEFSQSSHLQTHQRVHTVEK 10 20 30 770 780 790 800 810 820 pF1KSD SKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGM .: ::.. . .. : : . : .:: : .:. ::: : ::: . XP_016 P--FKCVECGKGFSRRSTLTVH-CKLH--SGEK----------PYNCEECGRAFIHASHL 40 50 60 70 830 840 850 860 870 880 pF1KSD QYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYH : :. : ::::.:. :: .: :.:.:: .:::..:. :. : :: .: : : XP_016 QEHQRI-HTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIH 80 90 100 110 120 130 890 900 910 920 930 940 pF1KSD TKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHT .. :. : : :. : : : ... : : :::.:::::. ::::: ..... : . XP_016 -QRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAH-QG 140 150 160 170 180 190 950 960 970 980 990 1000 pF1KSD FHNIEDPYDCKKCRMSFPTLQDHRKHIHEV-HSKEY-HPCPTCGKIFSAPSMLERHMVTH :. : :: :..: :: .. : . .: : :. : . : .::: : :.:. :. .: XP_016 VHTGEKPYKCNECGKSF-RMKIHYQ-VHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAH 200 210 220 230 240 250 1010 1020 1030 1040 1050 1060 pF1KSD VGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIE :::.: :.....: : : :. : . . .: : : : . XP_016 SVQKPFKCEECGQGFNQSSRLQIHQLIHTGE------------KPYKCEECGKGFSRRAD 260 270 280 290 300 1070 1080 1090 1100 1110 1120 pF1KSD HKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQ : : . :. : ..:..: ..: . : .: . ::: .::.: :. .: . :: XP_016 LKIHCRI-HTGEKPYNCEECGKVFSQASHLLTHQRV-HSGEKPFKCEECGKSFSRSAHLQ 310 320 330 340 350 1130 1140 1150 1160 1170 pF1KSD HHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLE---SEHPKVMSTE----TQAAASQM : .. . .: . : ::. : . .:: : . .:.: . . .::.. :. XP_016 AH---QKVHTGEKPYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQL 360 370 380 390 400 410 1180 1190 1200 1210 1220 1230 pF1KSD AQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDSQASQASSELVAVTVEDLLDGTVTL : ..: : XP_016 HQSVHTGEKPYKCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKI 420 430 440 450 460 470 >>XP_016881642 (OMIM: 604750) PREDICTED: zinc finger pro (502 aa) initn: 486 init1: 201 opt: 651 Z-score: 322.3 bits: 70.5 E(85289): 3.3e-11 Smith-Waterman score: 831; 32.1% identity (55.2% similar) in 458 aa overlap (733-1181:3-423) 710 720 730 740 750 760 pF1KSD SQPGEQNDQGETGSLPGQQEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAK .: . : .: : : .:..:.. : : XP_016 MGEKCYKCDVCGKEFSQSSHLQTHQRVHTVEK 10 20 30 770 780 790 800 810 820 pF1KSD SKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGM .: ::.. . .. : : . : .:: : .:. ::: : ::: . XP_016 P--FKCVECGKGFSRRSTLTVH-CKLH--SGEK----------PYNCEECGRAFIHASHL 40 50 60 70 830 840 850 860 870 880 pF1KSD QYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYH : :. : ::::.:. :: .: :.:.:: .:::..:. :. : :: .: : : XP_016 QEHQRI-HTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIH 80 90 100 110 120 130 890 900 910 920 930 940 pF1KSD TKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHT .. :. : : :. : : : ... : : :::.:::::. ::::: ..... : . XP_016 -QRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAH-QG 140 150 160 170 180 190 950 960 970 980 990 1000 pF1KSD FHNIEDPYDCKKCRMSFPTLQDHRKHIHEV-HSKEY-HPCPTCGKIFSAPSMLERHMVTH :. : :: :..: :: .. : . .: : :. : . : .::: : :.:. :. .: XP_016 VHTGEKPYKCNECGKSF-RMKIHYQ-VHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAH 200 210 220 230 240 250 1010 1020 1030 1040 1050 1060 pF1KSD VGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIE :::.: :.....: : : :. : . . .: : : : . XP_016 SVQKPFKCEECGQGFNQSSRLQIHQLIHTGE------------KPYKCEECGKGFSRRAD 260 270 280 290 300 1070 1080 1090 1100 1110 1120 pF1KSD HKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQ : : . :. : ..:..: ..: . : .: . ::: .::.: :. .: . :: XP_016 LKIHCRI-HTGEKPYNCEECGKVFSQASHLLTHQRV-HSGEKPFKCEECGKSFSRSAHLQ 310 320 330 340 350 1130 1140 1150 1160 1170 pF1KSD HHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLE---SEHPKVMSTE----TQAAASQM : .. . .: . : ::. : . .:: : . .:.: . . .::.. :. XP_016 AH---QKVHTGEKPYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQL 360 370 380 390 400 410 1180 1190 1200 1210 1220 1230 pF1KSD AQVIQTPEPVAPTEQVITLEETQLAGSQVFVTLPDSQASQASSELVAVTVEDLLDGTVTL : ..: : XP_016 HQSVHTGEKPYKCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKI 420 430 440 450 460 470 >>NP_001273627 (OMIM: 194552) zinc finger protein 79 iso (364 aa) initn: 567 init1: 213 opt: 647 Z-score: 321.9 bits: 69.9 E(85289): 3.5e-11 Smith-Waterman score: 758; 32.8% identity (61.3% similar) in 344 aa overlap (780-1122:32-357) 750 760 770 780 790 800 pF1KSD RLKVHMKRCRVAKSKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTC : .. :.: . . . : .. : .: NP_001 PPGDSDHGTSDLEKSFNLRPVLSPQQRVPVEARPRKCETHTESFKNSEILKPHRAKPYAC 10 20 30 40 50 60 810 820 830 840 850 860 pF1KSD DLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHC . ::. :.. :... :. . : :::. : ::: :. .:.: .: :.:::..:. :..: NP_001 NECGKAFSYCSSLSQHQKS-HTGEKPYECSECGKAFSQSSSLIQHQRIHTGEKPYKCSEC 70 80 90 100 110 120 870 880 890 900 910 920 pF1KSD LMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKG .:.: . :. : .. :. : : :. :. .:.. : .: : :::.::: : ::::. NP_001 GRAFSQNANLTKH-QRTHTGEKPYRCSECEKAFSDCSALVQHQRIHTGEKPYECSDCGKA 130 140 150 160 170 930 940 950 960 970 980 pF1KSD FRQANGLSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHIHEVHSKEY-HPCPTCGKIFS ::.. .:. : .: :. : :: :..: .: .: ...:. : . : .::: :: NP_001 FRHSANLTNHQRT-HTGEKPYKCSECGKAFSYCAAFIQH-QRIHTGEKPYRCAACGKAFS 180 190 200 210 220 230 990 1000 1010 1020 1030 1040 pF1KSD APSMLERHMVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFSSLQC . : :. ::.: ::..:. :.::..: ..: :..:: . . .: NP_001 QSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIHQKTHTGE------------KPYKC 240 250 260 270 280 1050 1060 1070 1080 1090 1100 pF1KSD SSCDKTFPNTIEHKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQHSGSQPFRCLY . : : : .. .: . :. : .::..: . : . :. : . :.: .:..: NP_001 NECGKFFSESSALIRH-HIIHTGEKPYECNECGKAFNQSSSLSQHQRI-HTGVKPYECSE 290 300 310 320 330 340 1110 1120 1130 1140 1150 1160 pF1KSD CAATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLESEHPKVMSTETQA :. .:: .:. .: NP_001 CGKAFRCSSAFVRHQRLHAGE 350 360 1239 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 01:52:03 2016 done: Thu Nov 3 01:52:05 2016 Total Scan time: 14.350 Total Display time: 0.310 Function used was FASTA [36.3.4 Apr, 2011]