Result of FASTA (omim) for pF1KSDA0544
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0544, 552 aa
  1>>>pF1KSDA0544 552 - 552 aa - 552 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.1566+/-0.000386; mu= 6.2178+/- 0.024
 mean_var=197.2630+/-40.129, 0's: 0 Z-trim(118.8): 74  B-trim: 0 in 0/55
 Lambda= 0.091317
 statistics sampled from 31980 (32056) to 31980 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.376), width:  16
 Scan time:  9.930

The best scores are:                                      opt bits E(85289)
NP_001135762 (OMIM: 607559) E3 ubiquitin-protein l ( 552) 3718 502.7 1.2e-141
XP_005255277 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 552) 3718 502.7 1.2e-141
XP_016878580 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 553) 3706 501.1 3.7e-141
XP_005255276 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 553) 3706 501.1 3.7e-141
NP_056061 (OMIM: 607559) E3 ubiquitin-protein liga ( 576) 3627 490.7 5.2e-138
XP_005255274 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 577) 3615 489.1 1.6e-137
XP_016878582 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 514) 3464 469.2 1.4e-131
XP_011520743 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 539) 3361 455.6 1.8e-127
NP_001135763 (OMIM: 607559) E3 ubiquitin-protein l ( 530) 2462 337.2 7.8e-92
XP_005255278 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 530) 2462 337.2 7.8e-92
XP_016878581 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 531) 2450 335.6 2.3e-91
NP_001135761 (OMIM: 607559) E3 ubiquitin-protein l ( 554) 2442 334.6   5e-91
XP_005255275 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 555) 2430 333.0 1.5e-90
XP_011520744 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 339) 1865 258.4 2.7e-68


>>NP_001135762 (OMIM: 607559) E3 ubiquitin-protein ligas  (552 aa)
 initn: 3718 init1: 3718 opt: 3718  Z-score: 2663.7  bits: 502.7 E(85289): 1.2e-141
Smith-Waterman score: 3718; 100.0% identity (100.0% similar) in 552 aa overlap (1-552:1-552)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
              490       500       510       520       530       540

              550  
pF1KSD LGPDSCSVGIDE
       ::::::::::::
NP_001 LGPDSCSVGIDE
              550  

>>XP_005255277 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (552 aa)
 initn: 3718 init1: 3718 opt: 3718  Z-score: 2663.7  bits: 502.7 E(85289): 1.2e-141
Smith-Waterman score: 3718; 100.0% identity (100.0% similar) in 552 aa overlap (1-552:1-552)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
              490       500       510       520       530       540

              550  
pF1KSD LGPDSCSVGIDE
       ::::::::::::
XP_005 LGPDSCSVGIDE
              550  

>>XP_016878580 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (553 aa)
 initn: 2306 init1: 2306 opt: 3706  Z-score: 2655.2  bits: 501.1 E(85289): 3.7e-141
Smith-Waterman score: 3706; 99.8% identity (99.8% similar) in 553 aa overlap (1-552:1-553)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200        210       220       230         
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGD-VVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_016 SEWKDDELNFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KSD KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KSD TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KSD KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
              490       500       510       520       530       540

     540       550  
pF1KSD ALGPDSCSVGIDE
       :::::::::::::
XP_016 ALGPDSCSVGIDE
              550   

>>XP_005255276 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (553 aa)
 initn: 2306 init1: 2306 opt: 3706  Z-score: 2655.2  bits: 501.1 E(85289): 3.7e-141
Smith-Waterman score: 3706; 99.8% identity (99.8% similar) in 553 aa overlap (1-552:1-553)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200        210       220       230         
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGD-VVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 SEWKDDELNFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KSD KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KSD TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KSD KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
              490       500       510       520       530       540

     540       550  
pF1KSD ALGPDSCSVGIDE
       :::::::::::::
XP_005 ALGPDSCSVGIDE
              550   

>>NP_056061 (OMIM: 607559) E3 ubiquitin-protein ligase M  (576 aa)
 initn: 3627 init1: 3627 opt: 3627  Z-score: 2598.7  bits: 490.7 E(85289): 5.2e-138
Smith-Waterman score: 3627; 100.0% identity (100.0% similar) in 539 aa overlap (1-539:1-539)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_056 GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPG
              490       500       510       520       530       540

              550                          
pF1KSD LGPDSCSVGIDE                        
                                           
NP_056 RPTSMETAHGLATTSPTWPPLGGPSPDPSAAELTPL
              550       560       570      

>>XP_005255274 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (577 aa)
 initn: 2215 init1: 2215 opt: 3615  Z-score: 2590.1  bits: 489.1 E(85289): 1.6e-137
Smith-Waterman score: 3615; 99.8% identity (99.8% similar) in 540 aa overlap (1-539:1-540)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200        210       220       230         
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGD-VVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 SEWKDDELNFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQ
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KSD KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLC
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KSD TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KSD KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGI
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLP
              490       500       510       520       530       540

     540       550                          
pF1KSD ALGPDSCSVGIDE                        
                                            
XP_005 GRPTSMETAHGLATTSPTWPPLGGPSPDPSAAELTPL
              550       560       570       

>>XP_016878582 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (514 aa)
 initn: 3464 init1: 3464 opt: 3464  Z-score: 2483.3  bits: 469.2 E(85289): 1.4e-131
Smith-Waterman score: 3464; 100.0% identity (100.0% similar) in 514 aa overlap (39-552:1-514)

       10        20        30        40        50        60        
pF1KSD IAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPV
                                     ::::::::::::::::::::::::::::::
XP_016                               MGGEKFDTPHPEGYLFGENMDLNFLGSRPV
                                             10        20        30

       70        80        90       100       110       120        
pF1KSD QFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADA
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KSD RVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDEL
              100       110       120       130       140       150

      190       200       210       220       230       240        
pF1KSD NFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVSY
              160       170       180       190       200       210

      250       260       270       280       290       300        
pF1KSD LLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRY
              220       230       240       250       260       270

      310       320       330       340       350       360        
pF1KSD QANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASL
              280       290       300       310       320       330

      370       380       390       400       410       420        
pF1KSD ASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQASC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQASC
              340       350       360       370       380       390

      430       440       450       460       470       480        
pF1KSD PLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELALR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELALR
              400       410       420       430       440       450

      490       500       510       520       530       540        
pF1KSD ESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPALGPDSCSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPALGPDSCSV
              460       470       480       490       500       510

      550  
pF1KSD GIDE
       ::::
XP_016 GIDE
           

>>XP_011520743 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (539 aa)
 initn: 2215 init1: 2215 opt: 3361  Z-score: 2409.7  bits: 455.6 E(85289): 1.8e-127
Smith-Waterman score: 3361; 99.8% identity (99.8% similar) in 502 aa overlap (39-539:1-502)

       10        20        30        40        50        60        
pF1KSD IAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPV
                                     ::::::::::::::::::::::::::::::
XP_011                               MGGEKFDTPHPEGYLFGENMDLNFLGSRPV
                                             10        20        30

       70        80        90       100       110       120        
pF1KSD QFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADA
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KSD RVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDEL
              100       110       120       130       140       150

      190       200        210       220       230       240       
pF1KSD NFDLDRGVFPVVIQAVVDEGD-VVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVS
       ::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 NFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVS
              160       170       180       190       200       210

       250       260       270       280       290       300       
pF1KSD YLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLR
              220       230       240       250       260       270

       310       320       330       340       350       360       
pF1KSD YQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPAS
              280       290       300       310       320       330

       370       380       390       400       410       420       
pF1KSD LASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQAS
              340       350       360       370       380       390

       430       440       450       460       470       480       
pF1KSD CPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELAL
              400       410       420       430       440       450

       490       500       510       520       530       540       
pF1KSD RESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPALGPDSCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
XP_011 RESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPGRPTSMET
              460       470       480       490       500       510

       550                          
pF1KSD VGIDE                        
                                    
XP_011 AHGLATTSPTWPPLGGPSPDPSAAELTPL
              520       530         

>>NP_001135763 (OMIM: 607559) E3 ubiquitin-protein ligas  (530 aa)
 initn: 2401 init1: 2401 opt: 2462  Z-score: 1769.7  bits: 337.2 E(85289): 7.8e-92
Smith-Waterman score: 3509; 96.0% identity (96.0% similar) in 552 aa overlap (1-552:1-530)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHS-----
              310       320       330       340       350          

              370       380       390       400       410       420
pF1KSD SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
                        :::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------------NSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
                          360       370       380       390        

              430       440       450       460       470       480
pF1KSD DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
      400       410       420       430       440       450        

              490       500       510       520       530       540
pF1KSD GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
      460       470       480       490       500       510        

              550  
pF1KSD LGPDSCSVGIDE
       ::::::::::::
NP_001 LGPDSCSVGIDE
      520       530

>>XP_005255278 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr  (530 aa)
 initn: 2401 init1: 2401 opt: 2462  Z-score: 1769.7  bits: 337.2 E(85289): 7.8e-92
Smith-Waterman score: 3509; 96.0% identity (96.0% similar) in 552 aa overlap (1-552:1-530)

               10        20        30        40        50        60
pF1KSD MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_005 SCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHS-----
              310       320       330       340       350          

              370       380       390       400       410       420
pF1KSD SKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
                        :::::::::::::::::::::::::::::::::::::::::::
XP_005 -----------------NSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGIS
                          360       370       380       390        

              430       440       450       460       470       480
pF1KSD DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPL
      400       410       420       430       440       450        

              490       500       510       520       530       540
pF1KSD GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPA
      460       470       480       490       500       510        

              550  
pF1KSD LGPDSCSVGIDE
       ::::::::::::
XP_005 LGPDSCSVGIDE
      520       530




552 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 02:01:18 2016 done: Thu Nov  3 02:01:19 2016
 Total Scan time:  9.930 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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