FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0552, 673 aa 1>>>pF1KSDA0552 673 - 673 aa - 673 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9280+/-0.000405; mu= -10.1839+/- 0.025 mean_var=417.5467+/-84.705, 0's: 0 Z-trim(123.3): 31 B-trim: 414 in 1/60 Lambda= 0.062766 statistics sampled from 42791 (42830) to 42791 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.502), width: 16 Scan time: 13.200 The best scores are: opt bits E(85289) XP_005260950 (OMIM: 610484) PREDICTED: leucine zip ( 673) 4435 416.1 2.1e-115 XP_005260949 (OMIM: 610484) PREDICTED: leucine zip ( 673) 4435 416.1 2.1e-115 XP_005260947 (OMIM: 610484) PREDICTED: leucine zip ( 703) 4435 416.1 2.2e-115 XP_011527710 (OMIM: 610484) PREDICTED: leucine zip ( 703) 4435 416.1 2.2e-115 XP_011527711 (OMIM: 610484) PREDICTED: leucine zip ( 703) 4435 416.1 2.2e-115 XP_011527709 (OMIM: 610484) PREDICTED: leucine zip ( 682) 2917 278.6 5.1e-74 NP_001269462 (OMIM: 610484) leucine zipper putativ ( 627) 2415 233.2 2.3e-60 NP_115805 (OMIM: 610454) leucine zipper putative t ( 669) 994 104.5 1.3e-21 NP_001305028 (OMIM: 610454) leucine zipper putativ ( 669) 994 104.5 1.3e-21 XP_005270279 (OMIM: 610454) PREDICTED: leucine zip ( 669) 994 104.5 1.3e-21 XP_016872269 (OMIM: 610454) PREDICTED: leucine zip ( 669) 994 104.5 1.3e-21 NP_001305029 (OMIM: 610454) leucine zipper putativ ( 669) 994 104.5 1.3e-21 NP_001305030 (OMIM: 610454) leucine zipper putativ ( 449) 768 83.9 1.4e-15 XP_016872270 (OMIM: 610454) PREDICTED: leucine zip ( 449) 768 83.9 1.4e-15 XP_011542687 (OMIM: 133239,606551) PREDICTED: leuc ( 596) 562 65.4 7.3e-10 NP_066300 (OMIM: 133239,606551) leucine zipper put ( 596) 562 65.4 7.3e-10 XP_011542688 (OMIM: 133239,606551) PREDICTED: leuc ( 596) 562 65.4 7.3e-10 XP_011542686 (OMIM: 133239,606551) PREDICTED: leuc ( 596) 562 65.4 7.3e-10 XP_011542685 (OMIM: 133239,606551) PREDICTED: leuc ( 596) 562 65.4 7.3e-10 XP_005273451 (OMIM: 133239,606551) PREDICTED: leuc ( 596) 562 65.4 7.3e-10 >>XP_005260950 (OMIM: 610484) PREDICTED: leucine zipper (673 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 2192.7 bits: 416.1 E(85289): 2.1e-115 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 673 aa overlap (1-673:1-673) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW 610 620 630 640 650 660 670 pF1KSD TPSRLERIESTEI ::::::::::::: XP_005 TPSRLERIESTEI 670 >>XP_005260949 (OMIM: 610484) PREDICTED: leucine zipper (673 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 2192.7 bits: 416.1 E(85289): 2.1e-115 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 673 aa overlap (1-673:1-673) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW 610 620 630 640 650 660 670 pF1KSD TPSRLERIESTEI ::::::::::::: XP_005 TPSRLERIESTEI 670 >>XP_005260947 (OMIM: 610484) PREDICTED: leucine zipper (703 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 2192.5 bits: 416.1 E(85289): 2.2e-115 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 673 aa overlap (1-673:31-703) 10 20 30 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGP :::::::::::::::::::::::::::::: XP_005 MAPADRASEGPRLEDPSAPQPLGKCPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN 610 620 630 640 650 660 640 650 660 670 pF1KSD QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI ::::::::::::::::::::::::::::::::::::::::::: XP_005 QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI 670 680 690 700 >>XP_011527710 (OMIM: 610484) PREDICTED: leucine zipper (703 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 2192.5 bits: 416.1 E(85289): 2.2e-115 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 673 aa overlap (1-673:31-703) 10 20 30 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGP :::::::::::::::::::::::::::::: XP_011 MAPADRASEGPRLEDPSAPQPLGKCPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN 610 620 630 640 650 660 640 650 660 670 pF1KSD QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI ::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI 670 680 690 700 >>XP_011527711 (OMIM: 610484) PREDICTED: leucine zipper (703 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 2192.5 bits: 416.1 E(85289): 2.2e-115 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 673 aa overlap (1-673:31-703) 10 20 30 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGP :::::::::::::::::::::::::::::: XP_011 MAPADRASEGPRLEDPSAPQPLGKCPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN 610 620 630 640 650 660 640 650 660 670 pF1KSD QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI ::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI 670 680 690 700 >>XP_011527709 (OMIM: 610484) PREDICTED: leucine zipper (682 aa) initn: 2911 init1: 2911 opt: 2917 Z-score: 1449.8 bits: 278.6 E(85289): 5.1e-74 Smith-Waterman score: 4237; 96.9% identity (96.9% similar) in 673 aa overlap (1-673:31-682) 10 20 30 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGP :::::::::::::::::::::::::::::: XP_011 MAPADRASEGPRLEDPSAPQPLGKCPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSED 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLATSGK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGY 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSPPSPSALIQELEERLWE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD LQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEIS :::::::::::::::::::::::::::::: ::::::::: XP_011 LQVLRLQQDKKQLQEEAARLMRQREELEDK---------------------VCQKAGEIS 430 440 450 460 470 480 490 500 510 pF1KSD LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KSD ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELPAACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSVDGEAEAGGESGT 520 530 540 550 560 570 580 590 600 610 620 630 pF1KSD RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRN 580 590 600 610 620 630 640 650 660 670 pF1KSD QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI ::::::::::::::::::::::::::::::::::::::::::: XP_011 QQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI 640 650 660 670 680 >>NP_001269462 (OMIM: 610484) leucine zipper putative tu (627 aa) initn: 2455 init1: 2375 opt: 2415 Z-score: 1204.6 bits: 233.2 E(85289): 2.3e-60 Smith-Waterman score: 4035; 93.2% identity (93.2% similar) in 673 aa overlap (1-673:1-627) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSSSGGSDKAPPQYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGSGSGLSDSGRNSLTSLPTYSSSYSQHLAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSASTSHINRIGTASYGSGSGGSSGGGSGYQDLGTSDSGRASSKSGSSSSMGRPGHLGSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAW ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGGGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQ--------- 310 320 330 340 350 370 380 390 400 410 420 pF1KSD ERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDK ::::::::::::::::::::::: NP_001 -------------------------------------QDKKQLQEEAARLMRQREELEDK 360 370 430 440 450 460 470 480 pF1KSD VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREG 380 390 400 410 420 430 490 500 510 520 530 540 pF1KSD RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RASLREKEEQLLSLRDSFSSKQASLELGEGELPAACLKPALTPVDPAEPQDALATCESDE 440 450 460 470 480 490 550 560 570 580 590 600 pF1KSD AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKMRRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAE 500 510 520 530 540 550 610 620 630 640 650 660 pF1KSD ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAW 560 570 580 590 600 610 670 pF1KSD TPSRLERIESTEI ::::::::::::: NP_001 TPSRLERIESTEI 620 >>NP_115805 (OMIM: 610454) leucine zipper putative tumor (669 aa) initn: 847 init1: 537 opt: 994 Z-score: 508.8 bits: 104.5 E(85289): 1.3e-21 Smith-Waterman score: 1114; 38.9% identity (59.5% similar) in 696 aa overlap (1-639:1-637) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :: ..:::: .:. : : ::. .: .::::.: .. : NP_115 MAIVQTLPVPLEPA--PEAATAPQ----AP-----VMGSVSSLIS----------GRPCP 10 20 30 70 80 90 100 110 pF1KSD GGGSQGSFPGPRG-----SGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNV :: . :: : . .: : : : ... : .. . .. : . . NP_115 GGPAPPRHHGPPGPTFFRQQDGLLR---GGYEAQEP-LCPAVPPRKAVPVTSFTYINEDF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KSD VGSSGGSSSSGGSDKAPPQYREPSH----PPKLLATSGKLDQCSEP-LVRPSAFKPVVPK : : :: : : : . .: ::::. .::::.. : :.::.:::::.:: NP_115 RTESPPSPSSDVED-AREQRAHNAHLRGPPPKLIPVSGKLEKNMEKILIRPTAFKPVLPK 100 110 120 130 140 150 180 190 200 210 pF1KSD --NFHSMQNLCPPQTNGTPEGRQGP-----GGLKGGLDKSRTMT----P------AGGSG . :. .. :...: : :: :: .. ..: . . : :.: NP_115 PRGAPSLPSFMGPRATGLS-GSQGSLTQLFGGPASSSSSSSSSSAADKPLAFSGWASGCP 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD SG-LSDSGRNSLTSLPTYSSSYSQHLAPLSASTS-HINRIGTASYGSGSGGSSGGGSGYQ :: :::::::::.::::::.. .. : ..: . :. :.::: :. : . : NP_115 SGTLSDSGRNSLSSLPTYSTGGAE---PTTSSPGGHL-----PSHGSGRGALPGPARGVP 220 230 240 250 260 280 290 300 310 320 pF1KSD DLGT-SDSGRASSKSGSSSSMGR--PGHLGSGEGG-------GGGLPFAACSPPSPSALI . :::::.::.....: :: : :::: . : : ::: ::. NP_115 TGPSHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALL 270 280 290 300 310 320 330 340 350 360 370 380 pF1KSD QE-LEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVAR . :: .: ..: :. :: ::...::.. :. ::::. :.:: ::. :... :. NP_115 HCVLEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQ----AQ 330 340 350 360 370 380 390 400 410 420 430 440 pF1KSD RAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKW ::::::: :::::..:::.:.:::.. :.:...::.:: . :. ..:: .. ::.::::: NP_115 RAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKW 390 400 410 420 430 440 450 460 470 480 490 500 pF1KSD EVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSS :::::.:::::::::::.:::.. :: ::.:.:: :::.::.:: .: . .:... . NP_115 EVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAARA 450 460 470 480 490 500 510 520 530 540 pF1KSD KQASLE---------------LGE--GELPAACLKPALTPVDPAEPQDALATCESDEAKM .. :: : : :.: : :: :: : . ::::::. NP_115 RELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATA-DPFLLAESDEAKV 510 520 530 540 550 560 550 560 570 580 590 600 pF1KSD RRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAEERR .: :::.. :: .:: .: ::..:: ::: :.: :: :: NP_115 QR-----AAAGV---------GG-----SLRAQVERLRVELQRERRRGEEQRDSFEGERL 570 580 590 600 610 620 630 640 650 660 pF1KSD VWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPS .: :::.::.:::::: .:..::.::.:::..:.. NP_115 AWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEQAPCICL 610 620 630 640 650 660 670 pF1KSD RLERIESTEI NP_115 EEITATEI >>NP_001305028 (OMIM: 610454) leucine zipper putative tu (669 aa) initn: 847 init1: 537 opt: 994 Z-score: 508.8 bits: 104.5 E(85289): 1.3e-21 Smith-Waterman score: 1114; 38.9% identity (59.5% similar) in 696 aa overlap (1-639:1-637) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :: ..:::: .:. : : ::. .: .::::.: .. : NP_001 MAIVQTLPVPLEPA--PEAATAPQ----AP-----VMGSVSSLIS----------GRPCP 10 20 30 70 80 90 100 110 pF1KSD GGGSQGSFPGPRG-----SGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNV :: . :: : . .: : : : ... : .. . .. : . . NP_001 GGPAPPRHHGPPGPTFFRQQDGLLR---GGYEAQEP-LCPAVPPRKAVPVTSFTYINEDF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KSD VGSSGGSSSSGGSDKAPPQYREPSH----PPKLLATSGKLDQCSEP-LVRPSAFKPVVPK : : :: : : : . .: ::::. .::::.. : :.::.:::::.:: NP_001 RTESPPSPSSDVED-AREQRAHNAHLRGPPPKLIPVSGKLEKNMEKILIRPTAFKPVLPK 100 110 120 130 140 150 180 190 200 210 pF1KSD --NFHSMQNLCPPQTNGTPEGRQGP-----GGLKGGLDKSRTMT----P------AGGSG . :. .. :...: : :: :: .. ..: . . : :.: NP_001 PRGAPSLPSFMGPRATGLS-GSQGSLTQLFGGPASSSSSSSSSSAADKPLAFSGWASGCP 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD SG-LSDSGRNSLTSLPTYSSSYSQHLAPLSASTS-HINRIGTASYGSGSGGSSGGGSGYQ :: :::::::::.::::::.. .. : ..: . :. :.::: :. : . : NP_001 SGTLSDSGRNSLSSLPTYSTGGAE---PTTSSPGGHL-----PSHGSGRGALPGPARGVP 220 230 240 250 260 280 290 300 310 320 pF1KSD DLGT-SDSGRASSKSGSSSSMGR--PGHLGSGEGG-------GGGLPFAACSPPSPSALI . :::::.::.....: :: : :::: . : : ::: ::. NP_001 TGPSHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALL 270 280 290 300 310 320 330 340 350 360 370 380 pF1KSD QE-LEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVAR . :: .: ..: :. :: ::...::.. :. ::::. :.:: ::. :... :. NP_001 HCVLEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQ----AQ 330 340 350 360 370 380 390 400 410 420 430 440 pF1KSD RAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKW ::::::: :::::..:::.:.:::.. :.:...::.:: . :. ..:: .. ::.::::: NP_001 RAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKW 390 400 410 420 430 440 450 460 470 480 490 500 pF1KSD EVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSS :::::.:::::::::::.:::.. :: ::.:.:: :::.::.:: .: . .:... . NP_001 EVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAARA 450 460 470 480 490 500 510 520 530 540 pF1KSD KQASLE---------------LGE--GELPAACLKPALTPVDPAEPQDALATCESDEAKM .. :: : : :.: : :: :: : . ::::::. NP_001 RELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATA-DPFLLAESDEAKV 510 520 530 540 550 560 550 560 570 580 590 600 pF1KSD RRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAEERR .: :::.. :: .:: .: ::..:: ::: :.: :: :: NP_001 QR-----AAAGV---------GG-----SLRAQVERLRVELQRERRRGEEQRDSFEGERL 570 580 590 600 610 620 630 640 650 660 pF1KSD VWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPS .: :::.::.:::::: .:..::.::.:::..:.. NP_001 AWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEQAPCICL 610 620 630 640 650 660 670 pF1KSD RLERIESTEI NP_001 EEITATEI >>XP_005270279 (OMIM: 610454) PREDICTED: leucine zipper (669 aa) initn: 847 init1: 537 opt: 994 Z-score: 508.8 bits: 104.5 E(85289): 1.3e-21 Smith-Waterman score: 1114; 38.9% identity (59.5% similar) in 696 aa overlap (1-639:1-637) 10 20 30 40 50 60 pF1KSD MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTG :: ..:::: .:. : : ::. .: .::::.: .. : XP_005 MAIVQTLPVPLEPA--PEAATAPQ----AP-----VMGSVSSLIS----------GRPCP 10 20 30 70 80 90 100 110 pF1KSD GGGSQGSFPGPRG-----SGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNV :: . :: : . .: : : : ... : .. . .. : . . XP_005 GGPAPPRHHGPPGPTFFRQQDGLLR---GGYEAQEP-LCPAVPPRKAVPVTSFTYINEDF 40 50 60 70 80 90 120 130 140 150 160 170 pF1KSD VGSSGGSSSSGGSDKAPPQYREPSH----PPKLLATSGKLDQCSEP-LVRPSAFKPVVPK : : :: : : : . .: ::::. .::::.. : :.::.:::::.:: XP_005 RTESPPSPSSDVED-AREQRAHNAHLRGPPPKLIPVSGKLEKNMEKILIRPTAFKPVLPK 100 110 120 130 140 150 180 190 200 210 pF1KSD --NFHSMQNLCPPQTNGTPEGRQGP-----GGLKGGLDKSRTMT----P------AGGSG . :. .. :...: : :: :: .. ..: . . : :.: XP_005 PRGAPSLPSFMGPRATGLS-GSQGSLTQLFGGPASSSSSSSSSSAADKPLAFSGWASGCP 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD SG-LSDSGRNSLTSLPTYSSSYSQHLAPLSASTS-HINRIGTASYGSGSGGSSGGGSGYQ :: :::::::::.::::::.. .. : ..: . :. :.::: :. : . : XP_005 SGTLSDSGRNSLSSLPTYSTGGAE---PTTSSPGGHL-----PSHGSGRGALPGPARGVP 220 230 240 250 260 280 290 300 310 320 pF1KSD DLGT-SDSGRASSKSGSSSSMGR--PGHLGSGEGG-------GGGLPFAACSPPSPSALI . :::::.::.....: :: : :::: . : : ::: ::. XP_005 TGPSHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALL 270 280 290 300 310 320 330 340 350 360 370 380 pF1KSD QE-LEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVAR . :: .: ..: :. :: ::...::.. :. ::::. :.:: ::. :... :. XP_005 HCVLEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQ----AQ 330 340 350 360 370 380 390 400 410 420 430 440 pF1KSD RAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKW ::::::: :::::..:::.:.:::.. :.:...::.:: . :. ..:: .. ::.::::: XP_005 RAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKW 390 400 410 420 430 440 450 460 470 480 490 500 pF1KSD EVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSS :::::.:::::::::::.:::.. :: ::.:.:: :::.::.:: .: . .:... . XP_005 EVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAARA 450 460 470 480 490 500 510 520 530 540 pF1KSD KQASLE---------------LGE--GELPAACLKPALTPVDPAEPQDALATCESDEAKM .. :: : : :.: : :: :: : . ::::::. XP_005 RELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATA-DPFLLAESDEAKV 510 520 530 540 550 560 550 560 570 580 590 600 pF1KSD RRQAGVAAAASLVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAEERR .: :::.. :: .:: .: ::..:: ::: :.: :: :: XP_005 QR-----AAAGV---------GG-----SLRAQVERLRVELQRERRRGEEQRDSFEGERL 570 580 590 600 610 620 630 640 650 660 pF1KSD VWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPS .: :::.::.:::::: .:..::.::.:::..:.. XP_005 AWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEQAPCICL 610 620 630 640 650 660 670 pF1KSD RLERIESTEI XP_005 EEITATEI 673 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:04:04 2016 done: Thu Nov 3 02:04:06 2016 Total Scan time: 13.200 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]