FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0592, 1320 aa 1>>>pF1KSDA0592 1320 - 1320 aa - 1320 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0854+/-0.00105; mu= 6.3427+/- 0.063 mean_var=197.4479+/-40.064, 0's: 0 Z-trim(111.2): 20 B-trim: 139 in 1/49 Lambda= 0.091274 statistics sampled from 12147 (12159) to 12147 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.374), width: 16 Scan time: 4.940 The best scores are: opt bits E(32554) CCDS44374.2 WASHC2C gene_id:253725|Hs108|chr10 (1320) 8599 1145.9 0 CCDS76303.1 WASHC2A gene_id:387680|Hs108|chr10 (1320) 8511 1134.3 0 CCDS81453.1 WASHC2C gene_id:253725|Hs108|chr10 (1341) 6164 825.2 0 CCDS41527.1 WASHC2A gene_id:387680|Hs108|chr10 (1341) 6079 814.0 0 CCDS53528.1 WASHC2C gene_id:253725|Hs108|chr10 (1279) 5836 782.0 0 CCDS81463.1 WASHC2A gene_id:387680|Hs108|chr10 (1279) 5773 773.7 0 CCDS53529.1 WASHC2C gene_id:253725|Hs108|chr10 (1245) 3727 504.3 8.2e-142 >>CCDS44374.2 WASHC2C gene_id:253725|Hs108|chr10 (1320 aa) initn: 8599 init1: 8599 opt: 8599 Z-score: 6126.3 bits: 1145.9 E(32554): 0 Smith-Waterman score: 8599; 99.8% identity (99.9% similar) in 1320 aa overlap (1-1320:1-1320) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS44 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS44 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS44 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1270 1280 1290 1300 1310 1320 >>CCDS76303.1 WASHC2A gene_id:387680|Hs108|chr10 (1320 aa) initn: 8511 init1: 8511 opt: 8511 Z-score: 6063.7 bits: 1134.3 E(32554): 0 Smith-Waterman score: 8511; 98.8% identity (99.5% similar) in 1320 aa overlap (1-1320:1-1320) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS76 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA ::::::.:::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS76 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE ::::::::::::::.::::::::::::: :::::::::::::::::::::::: :::::: CCDS76 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS76 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA ::::::::::::::.::::.:::::::::::::::::::::::::::::::::::::::: CCDS76 TRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 PWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 NSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1270 1280 1290 1300 1310 1320 >>CCDS81453.1 WASHC2C gene_id:253725|Hs108|chr10 (1341 aa) initn: 6157 init1: 6105 opt: 6164 Z-score: 4393.3 bits: 825.2 E(32554): 0 Smith-Waterman score: 8547; 98.2% identity (98.4% similar) in 1341 aa overlap (1-1320:1-1341) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS81 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQ---------------------AN ::::::::::::::::::::::::::::::::::::: :: CCDS81 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHR ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: CCDS81 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHR 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: CCDS81 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPE 1270 1280 1290 1300 1310 1320 1300 1310 1320 pF1KSD PRFEHKVSNIFDDPLNAFGGQ ::::::::::::::::::::: CCDS81 PRFEHKVSNIFDDPLNAFGGQ 1330 1340 >>CCDS41527.1 WASHC2A gene_id:387680|Hs108|chr10 (1341 aa) initn: 6085 init1: 6029 opt: 6079 Z-score: 4332.8 bits: 814.0 E(32554): 0 Smith-Waterman score: 8459; 97.2% identity (98.0% similar) in 1341 aa overlap (1-1320:1-1341) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS41 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA ::::::.:::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS41 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE ::::::::::::::.::::::::::::: :::::::::::::::::::::::: :::::: CCDS41 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS41 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQ---------------------AN ::::::::::.:::::::::::::::::::::::::: :: CCDS41 KRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHR :::::::::::::::::::::::::::::::::::.::::.::::::::::::::::::: CCDS41 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHR 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: CCDS41 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGT 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS41 LLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE 1270 1280 1290 1300 1310 1320 1300 1310 1320 pF1KSD PRFEHKVSNIFDDPLNAFGGQ ::::::::::::::::::::: CCDS41 PRFEHKVSNIFDDPLNAFGGQ 1330 1340 >>CCDS53528.1 WASHC2C gene_id:253725|Hs108|chr10 (1279 aa) initn: 5871 init1: 5819 opt: 5836 Z-score: 4160.2 bits: 782.0 E(32554): 0 Smith-Waterman score: 8228; 96.7% identity (96.8% similar) in 1320 aa overlap (1-1320:1-1279) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS53 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL---- 850 860 870 880 890 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP ::::::::::::::::::::::: CCDS53 -------------------------------------ANLAINPAALLPTAASQISEVKP 900 910 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS53 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS53 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1220 1230 1240 1250 1260 1270 >>CCDS81463.1 WASHC2A gene_id:387680|Hs108|chr10 (1279 aa) initn: 5804 init1: 5748 opt: 5773 Z-score: 4115.3 bits: 773.7 E(32554): 0 Smith-Waterman score: 8145; 95.8% identity (96.4% similar) in 1320 aa overlap (1-1320:1-1279) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 AVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS81 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA ::::::.:::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS81 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE ::::::::::::::.::::::::::::: :::::::::::::::::::::::: :::::: CCDS81 EEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS81 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL---- 850 860 870 880 890 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP ::::::::::::::::::::::: CCDS81 -------------------------------------ANLAINPAALLPTAASQISEVKP 900 910 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA ::::::::::::::.::::.:::::::::::::::::::::::::::::::::::::::: CCDS81 TRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 NSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1220 1230 1240 1250 1260 1270 >>CCDS53529.1 WASHC2C gene_id:253725|Hs108|chr10 (1245 aa) initn: 5754 init1: 3667 opt: 3727 Z-score: 2659.4 bits: 504.3 E(32554): 8.2e-142 Smith-Waterman score: 7959; 94.0% identity (94.2% similar) in 1320 aa overlap (1-1320:1-1245) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::: .::::::::::::::::::::::::: CCDS53 AMGRVDEEPT------------------------NEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS53 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 460 470 480 490 500 510 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATK------ 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS ::::::::::::::: CCDS53 ---------------------------------------------EGLLTRSAQETVKHS 700 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 710 720 730 740 750 760 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 770 780 790 800 810 820 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 830 840 850 860 870 880 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 890 900 910 920 930 940 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS53 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 950 960 970 980 990 1000 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1010 1020 1030 1040 1050 1060 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1070 1080 1090 1100 1110 1120 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1130 1140 1150 1160 1170 1180 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS53 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1190 1200 1210 1220 1230 1240 1320 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:13:43 2016 done: Thu Nov 3 02:13:44 2016 Total Scan time: 4.940 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]