FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0592, 1320 aa 1>>>pF1KSDA0592 1320 - 1320 aa - 1320 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7160+/-0.000419; mu= 2.5223+/- 0.026 mean_var=224.1377+/-44.671, 0's: 0 Z-trim(119.2): 32 B-trim: 0 in 0/51 Lambda= 0.085668 statistics sampled from 32857 (32889) to 32857 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.386), width: 16 Scan time: 14.940 The best scores are: opt bits E(85289) NP_056077 (OMIM: 613631) WASH complex subunit FAM2 (1320) 8599 1076.8 0 XP_016871511 (OMIM: 613631) PREDICTED: WASH comple (1233) 8014 1004.5 0 XP_016871504 (OMIM: 613631) PREDICTED: WASH comple (1296) 6433 809.1 0 NP_001317003 (OMIM: 613631) WASH complex subunit F (1341) 6164 775.8 0 XP_011537870 (OMIM: 613631) PREDICTED: WASH comple (1312) 5974 752.3 4.9e-216 XP_011537873 (OMIM: 613631) PREDICTED: WASH comple (1208) 5868 739.2 4e-212 XP_016871503 (OMIM: 613631) PREDICTED: WASH comple (1300) 5861 738.4 7.8e-212 NP_001162577 (OMIM: 613631) WASH complex subunit F (1279) 5836 735.3 6.6e-211 XP_016871510 (OMIM: 613631) PREDICTED: WASH comple (1254) 5579 703.5 2.4e-201 XP_016871505 (OMIM: 613631) PREDICTED: WASH comple (1291) 5072 640.9 1.8e-182 XP_011537872 (OMIM: 613631) PREDICTED: WASH comple (1283) 5037 636.5 3.5e-181 XP_011537871 (OMIM: 613631) PREDICTED: WASH comple (1290) 4742 600.1 3.3e-170 XP_016871507 (OMIM: 613631) PREDICTED: WASH comple (1269) 4686 593.1 4e-168 XP_011537874 (OMIM: 613631) PREDICTED: WASH comple ( 729) 4408 558.7 5.5e-158 XP_016871515 (OMIM: 613631) PREDICTED: WASH comple ( 634) 4052 514.6 8.7e-145 XP_011537869 (OMIM: 613631) PREDICTED: WASH comple (1317) 3998 508.1 1.6e-142 NP_001162578 (OMIM: 613631) WASH complex subunit F (1245) 3727 474.6 1.9e-132 XP_016871512 (OMIM: 613631) PREDICTED: WASH comple (1168) 3670 467.6 2.4e-130 XP_016871509 (OMIM: 613631) PREDICTED: WASH comple (1255) 3670 467.6 2.5e-130 XP_016871506 (OMIM: 613631) PREDICTED: WASH comple (1288) 2636 339.8 7.5e-92 XP_016871508 (OMIM: 613631) PREDICTED: WASH comple (1266) 2595 334.7 2.5e-90 XP_011537875 (OMIM: 613631) PREDICTED: WASH comple ( 709) 2538 327.5 2e-88 XP_016871513 (OMIM: 613631) PREDICTED: WASH comple ( 711) 2538 327.5 2e-88 XP_016871514 (OMIM: 613631) PREDICTED: WASH comple ( 711) 2538 327.5 2e-88 >>NP_056077 (OMIM: 613631) WASH complex subunit FAM21C i (1320 aa) initn: 8599 init1: 8599 opt: 8599 Z-score: 5752.8 bits: 1076.8 E(85289): 0 Smith-Waterman score: 8599; 99.8% identity (99.9% similar) in 1320 aa overlap (1-1320:1-1320) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_056 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_056 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_056 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1270 1280 1290 1300 1310 1320 >>XP_016871511 (OMIM: 613631) PREDICTED: WASH complex su (1233 aa) initn: 8014 init1: 8014 opt: 8014 Z-score: 5362.5 bits: 1004.5 E(85289): 0 Smith-Waterman score: 8014; 99.8% identity (99.9% similar) in 1233 aa overlap (88-1320:1-1233) 60 70 80 90 100 110 pF1KSD THEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTE :::::::::::::::::::::::::::::: XP_016 MLSNTQFIENRVYDEEVEEPVLKAEAEKTE 10 20 30 120 130 140 150 160 170 pF1KSD QEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKD 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD LYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHH 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD SDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARI 160 170 180 190 200 210 300 310 320 330 340 350 pF1KSD KGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSG 220 230 240 250 260 270 360 370 380 390 400 410 pF1KSD GGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTD 280 290 300 310 320 330 420 430 440 450 460 470 pF1KSD VFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQ 340 350 360 370 380 390 480 490 500 510 520 530 pF1KSD STADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGL ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 STADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KSD FSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQA 460 470 480 490 500 510 600 610 620 630 640 650 pF1KSD QREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAK 520 530 540 550 560 570 660 670 680 690 700 710 pF1KSD AVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKE 580 590 600 610 620 630 720 730 740 750 760 770 pF1KSD TVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETV 640 650 660 670 680 690 780 790 800 810 820 830 pF1KSD KHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKST 700 710 720 730 740 750 840 850 860 870 880 890 pF1KSD GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV 760 770 780 790 800 810 900 910 920 930 940 950 pF1KSD QEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISE 820 830 840 850 860 870 960 970 980 990 1000 1010 pF1KSD VKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKR 880 890 900 910 920 930 1020 1030 1040 1050 1060 1070 pF1KSD RPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAA ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 RPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAA 940 950 960 970 980 990 1080 1090 1100 1110 1120 1130 pF1KSD AAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENP 1000 1010 1020 1030 1040 1050 1140 1150 1160 1170 1180 1190 pF1KSD ANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNE 1060 1070 1080 1090 1100 1110 1200 1210 1220 1230 1240 1250 pF1KSD TKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPK 1120 1130 1140 1150 1160 1170 1260 1270 1280 1290 1300 1310 pF1KSD EKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAF ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 EKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAF 1180 1190 1200 1210 1220 1230 1320 pF1KSD GGQ ::: XP_016 GGQ >>XP_016871504 (OMIM: 613631) PREDICTED: WASH complex su (1296 aa) initn: 6411 init1: 6411 opt: 6433 Z-score: 4306.1 bits: 809.1 E(85289): 0 Smith-Waterman score: 8380; 97.9% identity (98.1% similar) in 1320 aa overlap (1-1320:1-1296) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::: .::::::::::::::::::::::::: XP_016 AMGRVDEEPT------------------------NEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 460 470 480 490 500 510 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 760 770 780 790 800 810 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 820 830 840 850 860 870 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_016 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_016 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1240 1250 1260 1270 1280 1290 >>NP_001317003 (OMIM: 613631) WASH complex subunit FAM21 (1341 aa) initn: 6157 init1: 6105 opt: 6164 Z-score: 4126.2 bits: 775.8 E(85289): 0 Smith-Waterman score: 8547; 98.2% identity (98.4% similar) in 1341 aa overlap (1-1320:1-1341) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 850 860 870 880 890 900 910 920 930 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQ---------------------AN ::::::::::::::::::::::::::::::::::::: :: NP_001 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHR ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_001 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHR 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_001 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPE 1270 1280 1290 1300 1310 1320 1300 1310 1320 pF1KSD PRFEHKVSNIFDDPLNAFGGQ ::::::::::::::::::::: NP_001 PRFEHKVSNIFDDPLNAFGGQ 1330 1340 >>XP_011537870 (OMIM: 613631) PREDICTED: WASH complex su (1312 aa) initn: 5905 init1: 3411 opt: 5974 Z-score: 3999.5 bits: 752.3 E(85289): 4.9e-216 Smith-Waterman score: 8312; 96.1% identity (96.3% similar) in 1341 aa overlap (1-1320:1-1312) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::: XP_011 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK------------------------ 490 500 510 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -----DLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 760 770 780 790 800 810 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 820 830 840 850 860 870 910 920 930 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQ---------------------AN ::::::::::::::::::::::::::::::::::::: :: XP_011 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQAN 880 890 900 910 920 930 940 950 960 970 980 990 pF1KSD LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQ 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHR ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_011 ADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHR 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 pF1KSD PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGT 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KSD GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFP 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KSD LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLES 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 pF1KSD NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPE ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_011 NLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPE 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD PRFEHKVSNIFDDPLNAFGGQ ::::::::::::::::::::: XP_011 PRFEHKVSNIFDDPLNAFGGQ 1300 1310 >>XP_011537873 (OMIM: 613631) PREDICTED: WASH complex su (1208 aa) initn: 5879 init1: 5827 opt: 5868 Z-score: 3929.2 bits: 739.2 E(85289): 4e-212 Smith-Waterman score: 7631; 91.3% identity (91.4% similar) in 1320 aa overlap (1-1320:1-1208) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL---- 850 860 870 880 890 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP XP_011 ------------------------------------------------------------ 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::: XP_011 ------------------------------------------------SRVKMRGKRRPQ 900 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 910 920 930 940 950 960 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 970 980 990 1000 1010 1020 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1030 1040 1050 1060 1070 1080 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1090 1100 1110 1120 1130 1140 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1150 1160 1170 1180 1190 1200 >>XP_016871503 (OMIM: 613631) PREDICTED: WASH complex su (1300 aa) initn: 8313 init1: 5819 opt: 5861 Z-score: 3924.1 bits: 738.4 E(85289): 7.8e-212 Smith-Waterman score: 8283; 97.2% identity (97.7% similar) in 1321 aa overlap (1-1320:1-1300) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL---- 850 860 870 880 890 910 920 930 940 950 pF1KSD KRVVKKDHS-VNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVK : : . ::. :.: . :. ::::::::::::::::::::::: XP_016 ------DSSGLAPFKT-KEPSTRIGKI----------QANLAINPAALLPTAASQISEVK 900 910 920 930 960 970 980 990 1000 1010 pF1KSD PVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRP 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KSD QTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAA ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 QTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAA 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 pF1KSD APWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPAN 1060 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 pF1KSD PPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETK 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KSD SSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEK 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KSD SKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGG ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 SKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGG 1240 1250 1260 1270 1280 1290 1320 pF1KSD Q : XP_016 Q 1300 >>NP_001162577 (OMIM: 613631) WASH complex subunit FAM21 (1279 aa) initn: 5871 init1: 5819 opt: 5836 Z-score: 3907.5 bits: 735.3 E(85289): 6.6e-211 Smith-Waterman score: 8228; 96.7% identity (96.8% similar) in 1320 aa overlap (1-1320:1-1279) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPL---- 850 860 870 880 890 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP ::::::::::::::::::::::: NP_001 -------------------------------------ANLAINPAALLPTAASQISEVKP 900 910 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1220 1230 1240 1250 1260 1270 >>XP_016871510 (OMIM: 613631) PREDICTED: WASH complex su (1254 aa) initn: 5572 init1: 5520 opt: 5579 Z-score: 3735.9 bits: 703.5 E(85289): 2.4e-201 Smith-Waterman score: 7962; 98.1% identity (98.2% similar) in 1254 aa overlap (88-1320:1-1254) 60 70 80 90 100 110 pF1KSD THEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTE :::::::::::::::::::::::::::::: XP_016 MLSNTQFIENRVYDEEVEEPVLKAEAEKTE 10 20 30 120 130 140 150 160 170 pF1KSD QEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKD 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD LYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHH 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD SDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARI 160 170 180 190 200 210 300 310 320 330 340 350 pF1KSD KGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSG 220 230 240 250 260 270 360 370 380 390 400 410 pF1KSD GGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTD 280 290 300 310 320 330 420 430 440 450 460 470 pF1KSD VFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQ 340 350 360 370 380 390 480 490 500 510 520 530 pF1KSD STADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGL ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 STADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KSD FSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQA 460 470 480 490 500 510 600 610 620 630 640 650 pF1KSD QREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAK 520 530 540 550 560 570 660 670 680 690 700 710 pF1KSD AVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKE 580 590 600 610 620 630 720 730 740 750 760 770 pF1KSD TVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETV 640 650 660 670 680 690 780 790 800 810 820 830 pF1KSD KHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKST 700 710 720 730 740 750 840 850 860 870 880 890 pF1KSD GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV 760 770 780 790 800 810 900 910 920 930 pF1KSD QEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQ-------------------- :::::::::::::::::::::::::::::::::::::::: XP_016 QEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKI 820 830 840 850 860 870 940 950 960 970 980 990 pF1KSD -ANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDL 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KSD PAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPN :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 PAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPN 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KSD GHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFS 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KSD TGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTN 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KSD PFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKT 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KSD LESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQA :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 LESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQA 1180 1190 1200 1210 1220 1230 1300 1310 1320 pF1KSD APEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::::::: XP_016 APEPRFEHKVSNIFDDPLNAFGGQ 1240 1250 >>XP_016871505 (OMIM: 613631) PREDICTED: WASH complex su (1291 aa) initn: 5030 init1: 5030 opt: 5072 Z-score: 3397.1 bits: 640.9 E(85289): 1.8e-182 Smith-Waterman score: 8364; 97.7% identity (97.8% similar) in 1320 aa overlap (1-1320:1-1291) 10 20 30 40 50 60 pF1KSD MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD :::::::::::::::::::::::::::::::::::: XP_016 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK------------------------ 490 500 510 550 560 570 580 590 600 pF1KSD EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----DLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQRE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVS 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHS 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVF 760 770 780 790 800 810 850 860 870 880 890 900 pF1KSD QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK 820 830 840 850 860 870 910 920 930 940 950 960 pF1KSD KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKP 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KSD VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQ 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KSD TRAARRLAAQESSEAEDMSIPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_016 TRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAA 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KSD PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANP 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KSD PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKS 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KSD SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KSD KKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_016 KKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1240 1250 1260 1270 1280 1290 1320 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:13:44 2016 done: Thu Nov 3 02:13:46 2016 Total Scan time: 14.940 Total Display time: 0.520 Function used was FASTA [36.3.4 Apr, 2011]