FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0607, 712 aa 1>>>pF1KSDA0607 712 - 712 aa - 712 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9355+/-0.000363; mu= 22.3858+/- 0.023 mean_var=69.5834+/-13.848, 0's: 0 Z-trim(114.0): 16 B-trim: 1250 in 1/52 Lambda= 0.153752 statistics sampled from 23661 (23677) to 23661 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.278), width: 16 Scan time: 11.750 The best scores are: opt bits E(85289) NP_001014841 (OMIM: 608458) neurochondrin isoform ( 712) 4722 1056.9 0 NP_055099 (OMIM: 608458) neurochondrin isoform 1 [ ( 729) 4722 1056.9 0 NP_001014839 (OMIM: 608458) neurochondrin isoform ( 729) 4722 1056.9 0 >>NP_001014841 (OMIM: 608458) neurochondrin isoform 2 [H (712 aa) initn: 4722 init1: 4722 opt: 4722 Z-score: 5655.0 bits: 1056.9 E(85289): 0 Smith-Waterman score: 4722; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:1-712) 10 20 30 40 50 60 pF1KSD MASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPEC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEAND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEAND 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD WELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPN 610 620 630 640 650 660 670 680 690 700 710 pF1KSD SVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP 670 680 690 700 710 >>NP_055099 (OMIM: 608458) neurochondrin isoform 1 [Homo (729 aa) initn: 4722 init1: 4722 opt: 4722 Z-score: 5654.9 bits: 1056.9 E(85289): 0 Smith-Waterman score: 4722; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:18-729) 10 20 30 40 pF1KSD MASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVT ::::::::::::::::::::::::::::::::::::::::::: NP_055 MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD KAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPEL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD AAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD LCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFEL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD CQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD SSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD KVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD LVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREI 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD LIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDA 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD CFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALR 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD SRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMA 670 680 690 700 710 720 710 pF1KSD ALEQCLSEP ::::::::: NP_055 ALEQCLSEP >>NP_001014839 (OMIM: 608458) neurochondrin isoform 1 [H (729 aa) initn: 4722 init1: 4722 opt: 4722 Z-score: 5654.9 bits: 1056.9 E(85289): 0 Smith-Waterman score: 4722; 100.0% identity (100.0% similar) in 712 aa overlap (1-712:18-729) 10 20 30 40 pF1KSD MASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVT ::::::::::::::::::::::::::::::::::::::::::: NP_001 MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVT 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD KAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPEL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD AAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD LCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFEL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD CQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD SSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD KVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD LVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREI 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD LIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDA 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD CFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALR 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD SRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMA 670 680 690 700 710 720 710 pF1KSD ALEQCLSEP ::::::::: NP_001 ALEQCLSEP 712 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:16:32 2016 done: Thu Nov 3 02:16:33 2016 Total Scan time: 11.750 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]