Result of FASTA (omim) for
pF1KSDA0613
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0613, 727 aa
1>>>pF1KSDA0613 727 - 727 aa - 727 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 18.6554+/-0.000534; mu= -43.4687+/- 0.033
mean_var=808.0351+/-171.948, 0's: 0 Z-trim(123.6): 229 B-trim: 1815 in 1/58
Lambda= 0.045119
statistics sampled from 43503 (43807) to 43503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.514), width: 16
Scan time: 14.020
The best scores are: opt bits E(85289)
NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727) 5011 341.8 5.7e-93
XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM ( 727) 5011 341.8 5.7e-93
NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732) 4141 285.2 6.4e-76
XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM ( 795) 3538 246.0 4.5e-64
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 3534 245.7 4.7e-64
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 2964 208.6 7.5e-53
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 2964 208.6 7.5e-53
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 2667 189.2 4.5e-47
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 2651 188.2 8.7e-47
XP_011537495 (OMIM: 605906,609452) PREDICTED: LIM ( 463) 2412 172.5 3.3e-42
XP_016871096 (OMIM: 605906,609452) PREDICTED: LIM ( 463) 2412 172.5 3.3e-42
XP_011537493 (OMIM: 605906,609452) PREDICTED: LIM ( 633) 2412 172.6 4.3e-42
XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM ( 696) 2412 172.6 4.7e-42
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 2412 172.7 5.3e-42
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 2412 172.7 5.3e-42
XP_011537496 (OMIM: 605906,609452) PREDICTED: LIM ( 400) 2366 169.5 2.3e-41
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 2366 169.7 3.9e-41
NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330) 1968 143.6 1.2e-33
XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 1968 143.6 1.2e-33
XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 1968 143.6 1.2e-33
XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 1662 123.8 2.4e-27
XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 1647 122.8 4.7e-27
XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM ( 398) 1532 115.2 5.1e-25
NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398) 1532 115.2 5.1e-25
XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 1316 101.3 1.5e-20
NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625) 1238 96.2 4.3e-19
XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630) 1237 96.1 4.5e-19
XP_005262753 (OMIM: 605904) PREDICTED: PDZ and LIM ( 619) 1233 95.9 5.4e-19
XP_006714133 (OMIM: 605904) PREDICTED: PDZ and LIM ( 605) 1224 95.3 7.9e-19
XP_011529845 (OMIM: 605904) PREDICTED: PDZ and LIM ( 600) 1222 95.1 8.6e-19
XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 1137 89.6 3.4e-17
XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 1127 88.9 5.3e-17
NP_001243357 (OMIM: 605904) PDZ and LIM domain pro ( 474) 1125 88.8 5.6e-17
NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 1125 88.8 6.8e-17
NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 1120 88.4 7.2e-17
XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 1119 88.4 9e-17
XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 1116 88.2 1e-16
NP_001243354 (OMIM: 605904) PDZ and LIM domain pro ( 271) 1100 87.0 1.1e-16
NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 1064 84.8 8.9e-16
NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 1030 82.6 3.9e-15
XP_011533000 (OMIM: 605903) PREDICTED: PDZ and LIM ( 364) 1019 81.8 5.3e-15
XP_011533001 (OMIM: 605903) PREDICTED: PDZ and LIM ( 309) 1009 81.1 7.3e-15
NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423) 1011 81.3 8.7e-15
NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283) 702 61.1 7e-09
XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM ( 283) 702 61.1 7e-09
NP_001035919 (OMIM: 602353) transforming growth fa ( 461) 621 56.0 4.1e-07
NP_002850 (OMIM: 602505) paxillin isoform 1 [Homo ( 557) 618 55.8 5.5e-07
XP_016875231 (OMIM: 602505) PREDICTED: paxillin is ( 563) 618 55.8 5.6e-07
NP_057011 (OMIM: 602353) transforming growth facto ( 444) 612 55.4 6e-07
NP_001158191 (OMIM: 602353) transforming growth fa ( 444) 612 55.4 6e-07
>>NP_009009 (OMIM: 605906,609452) LIM domain-binding pro (727 aa)
initn: 5011 init1: 5011 opt: 5011 Z-score: 1790.1 bits: 341.8 E(85289): 5.7e-93
Smith-Waterman score: 5011; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
670 680 690 700 710 720
pF1KSD HAHTINL
:::::::
NP_009 HAHTINL
>>XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM doma (727 aa)
initn: 5011 init1: 5011 opt: 5011 Z-score: 1790.1 bits: 341.8 E(85289): 5.7e-93
Smith-Waterman score: 5011; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
670 680 690 700 710 720
pF1KSD HAHTINL
:::::::
XP_005 HAHTINL
>>NP_001165081 (OMIM: 605906,609452) LIM domain-binding (732 aa)
initn: 4158 init1: 2643 opt: 4141 Z-score: 1484.0 bits: 285.2 E(85289): 6.4e-76
Smith-Waterman score: 4328; 83.5% identity (83.5% similar) in 795 aa overlap (1-727:1-732)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGG----------
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGADYQERFNPS
190 200 210 220 230 240
pF1KSD ----------------------------------------------------------SL
::
NP_001 ALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSL
250 260 270 280 290 300
240 250 260 270 280 290
pF1KSD PIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDE
310 320 330 340 350 360
300 310 320 330 340 350
pF1KSD EALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTA
::::::
NP_001 EALRRS------------------------------------------------------
360 370 380 390 400 410
pF1KSD PASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVP
370 380 390 400 410
420 430 440 450 460 470
pF1KSD ASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD PSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KSD RGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEE
540 550 560 570 580 590
600 610 620 630 640 650
pF1KSD QNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMED
600 610 620 630 640 650
660 670 680 690 700 710
pF1KSD GEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSK
660 670 680 690 700 710
720
pF1KSD KDRPLCKKHAHTINL
:::::::::::::::
NP_001 KDRPLCKKHAHTINL
720 730
>>XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM doma (795 aa)
initn: 3491 init1: 3491 opt: 3538 Z-score: 1271.3 bits: 246.0 E(85289): 4.5e-64
Smith-Waterman score: 4612; 91.0% identity (91.0% similar) in 759 aa overlap (37-727:37-795)
10 20 30 40 50 60
pF1KSD LTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQ
::::::::::::::::::::::::::::::
XP_011 LTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDLLGPKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDLLGPKAL
130 140 150 160 170 180
190 200 210 220 230
pF1KSD PGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGG----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGADYQERFNPSALKDSA
190 200 210 220 230 240
pF1KSD ----------------------------------------------------SLPIKDLA
::::::::
XP_011 LSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLA
250 260 270 280 290 300
240 250 260 270 280 290
pF1KSD VDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS
310 320 330 340 350 360
300 310 320 330 340 350
pF1KSD STPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPA
370 380 390 400 410 420
360 370 380 390 400 410
pF1KSD DSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSP
430 440 450 460 470 480
420 430 440 450 460 470
pF1KSD SPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYS
490 500 510 520 530 540
480 490 500 510 520 530
pF1KSD GGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQR
550 560 570 580 590 600
540 550 560 570 580 590
pF1KSD AERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYC
610 620 630 640 650 660
600 610 620 630 640 650
pF1KSD ERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE
670 680 690 700 710 720
660 670 680 690 700 710
pF1KSD KDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC
730 740 750 760 770 780
720
pF1KSD KKHAHTINL
:::::::::
XP_011 KKHAHTINL
790
>>XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM doma (680 aa)
initn: 4179 init1: 3491 opt: 3534 Z-score: 1270.9 bits: 245.7 E(85289): 4.7e-64
Smith-Waterman score: 4174; 86.4% identity (90.0% similar) in 727 aa overlap (1-727:1-680)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::: .:.
XP_011 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK---------VVVN
70 80 90 100 110
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::. . . . :.:. . ::.:. :
XP_011 SPA-----------NADYQERFNPSALKDSALSTHKPIEVKG------------------
120 130 140
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
:: :: . :::.::..:: ... : .. ...:.: . .:::::::::::
XP_011 LGGKA---TIIHAQYNTPISMYSQDAI-----MDAIAGQAQAQGSDF-SGSLPIKDLAVD
150 160 170 180 190
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
200 210 220 230 240 250
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
260 270 280 290 300 310
370 380 390 400 410 420
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
320 330 340 350 360 370
430 440 450 460 470 480
pF1KSD GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
380 390 400 410 420 430
490 500 510 520 530 540
pF1KSD PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
440 450 460 470 480 490
550 560 570 580 590 600
pF1KSD RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
500 510 520 530 540 550
610 620 630 640 650 660
pF1KSD CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
560 570 580 590 600 610
670 680 690 700 710 720
pF1KSD YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
620 630 640 650 660 670
pF1KSD HAHTINL
:::::::
XP_011 HAHTINL
680
>>XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM doma (743 aa)
initn: 3126 init1: 2868 opt: 2964 Z-score: 1069.8 bits: 208.6 E(85289): 7.5e-53
Smith-Waterman score: 4969; 97.8% identity (97.8% similar) in 743 aa overlap (1-727:1-743)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
310 320 330 340 350 360
370 380 390 400 410
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPAVGQNPMEPA
370 380 390 400 410 420
420 430 440 450 460
pF1KSD ------VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLGETVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD PAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD GPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFG
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD NSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNL
670 680 690 700 710 720
710 720
pF1KSD EGQPFYSKKDRPLCKKHAHTINL
:::::::::::::::::::::::
XP_011 EGQPFYSKKDRPLCKKHAHTINL
730 740
>>XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM doma (743 aa)
initn: 3126 init1: 2868 opt: 2964 Z-score: 1069.8 bits: 208.6 E(85289): 7.5e-53
Smith-Waterman score: 4969; 97.8% identity (97.8% similar) in 743 aa overlap (1-727:1-743)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
310 320 330 340 350 360
370 380 390 400 410
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPAVGQNPMEPA
370 380 390 400 410 420
420 430 440 450 460
pF1KSD ------VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLGETVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD PAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD GPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFG
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD NSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNL
670 680 690 700 710 720
710 720
pF1KSD EGQPFYSKKDRPLCKKHAHTINL
:::::::::::::::::::::::
XP_016 EGQPFYSKKDRPLCKKHAHTINL
730 740
>>XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM doma (664 aa)
initn: 2643 init1: 2643 opt: 2667 Z-score: 966.1 bits: 189.2 E(85289): 4.5e-47
Smith-Waterman score: 4474; 91.3% identity (91.3% similar) in 727 aa overlap (1-727:1-664)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS--
250 260 270 280 290
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
XP_005 ------------------------------------------------------------
370 380 390 400 410 420
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
300 310 320 330 340 350
430 440 450 460 470 480
pF1KSD GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
360 370 380 390 400 410
490 500 510 520 530 540
pF1KSD PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
420 430 440 450 460 470
550 560 570 580 590 600
pF1KSD RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
480 490 500 510 520 530
610 620 630 640 650 660
pF1KSD CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
540 550 560 570 580 590
670 680 690 700 710 720
pF1KSD YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
600 610 620 630 640 650
pF1KSD HAHTINL
:::::::
XP_005 HAHTINL
660
>>NP_001073583 (OMIM: 605906,609452) LIM domain-binding (617 aa)
initn: 3331 init1: 2643 opt: 2651 Z-score: 960.9 bits: 188.2 E(85289): 8.7e-47
Smith-Waterman score: 3637; 77.7% identity (81.3% similar) in 727 aa overlap (1-727:1-617)
10 20 30 40 50 60
pF1KSD MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP
::::::::::::::::::::::::::::::::::::::::::::::: .:.
NP_001 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK---------VVVN
70 80 90 100 110
130 140 150 160 170 180
pF1KSD SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL
::. . . . :.:. . ::.:. :
NP_001 SPA-----------NADYQERFNPSALKDSALSTHKPIEVKG------------------
120 130 140
190 200 210 220 230 240
pF1KSD LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD
:: :: . :::.::..:: ... : .. ...:.: . .:::::::::::
NP_001 LGGKA---TIIHAQYNTPISMYSQDAI-----MDAIAGQAQAQGSDF-SGSLPIKDLAVD
150 160 170 180 190
250 260 270 280 290 300
pF1KSD SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS--
200 210 220 230 240 250
310 320 330 340 350 360
pF1KSD PIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS
NP_001 ------------------------------------------------------------
370 380 390 400 410 420
pF1KSD PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -RPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSP
260 270 280 290 300 310
430 440 450 460 470 480
pF1KSD GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGG
320 330 340 350 360 370
490 500 510 520 530 540
pF1KSD PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAE
380 390 400 410 420 430
550 560 570 580 590 600
pF1KSD RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCER
440 450 460 470 480 490
610 620 630 640 650 660
pF1KSD CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD
500 510 520 530 540 550
670 680 690 700 710 720
pF1KSD YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKK
560 570 580 590 600 610
pF1KSD HAHTINL
:::::::
NP_001 HAHTINL
>>XP_011537495 (OMIM: 605906,609452) PREDICTED: LIM doma (463 aa)
initn: 2325 init1: 2325 opt: 2412 Z-score: 878.7 bits: 172.5 E(85289): 3.3e-42
Smith-Waterman score: 3122; 96.5% identity (96.5% similar) in 463 aa overlap (281-727:1-463)
260 270 280 290 300 310
pF1KSD KSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPIEHAPVCTS
::::::::::::::::::::::::::::::
XP_011 MTGTEFMQDPDEEALRRSSTPIEHAPVCTS
10 20 30
320 330 340 350 360 370
pF1KSD QATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQASSYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQASSYSP
40 50 60 70 80 90
380 390 400 410
pF1KSD AVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP----------------VPAS
:::::::::::::::::::::::::::::::::::::::: ::::
XP_011 AVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPAVGQNPMEPASGLGETVPAS
100 110 120 130 140 150
420 430 440 450 460 470
pF1KSD TYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPS
160 170 180 190 200 210
480 490 500 510 520 530
pF1KSD VAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARG
220 230 240 250 260 270
540 550 560 570 580 590
pF1KSD TVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQN
280 290 300 310 320 330
600 610 620 630 640 650
pF1KSD NVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE
340 350 360 370 380 390
660 670 680 690 700 710
pF1KSD PYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKD
400 410 420 430 440 450
720
pF1KSD RPLCKKHAHTINL
:::::::::::::
XP_011 RPLCKKHAHTINL
460
727 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:17:48 2016 done: Thu Nov 3 02:17:50 2016
Total Scan time: 14.020 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]