FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0639, 1826 aa 1>>>pF1KSDA0639 1826 - 1826 aa - 1826 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.0052+/-0.000549; mu= -15.4348+/- 0.034 mean_var=529.6764+/-109.623, 0's: 0 Z-trim(119.8): 284 B-trim: 532 in 1/60 Lambda= 0.055727 statistics sampled from 34018 (34303) to 34018 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.402), width: 16 Scan time: 20.390 The best scores are: opt bits E(85289) NP_056069 (OMIM: 607350) kinesin-like protein KIF1 (1826) 12051 985.5 0 XP_011542760 (OMIM: 607350) PREDICTED: kinesin-lik (1826) 11228 919.3 0 XP_005273515 (OMIM: 607350) PREDICTED: kinesin-lik (1805) 9827 806.7 0 XP_011542759 (OMIM: 607350) PREDICTED: kinesin-lik (1847) 9159 753.0 6.2e-216 XP_016868746 (OMIM: 607350) PREDICTED: kinesin-lik (1490) 9088 747.2 2.7e-214 XP_011542763 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 8719 717.6 2.7e-205 XP_011542762 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 8719 717.6 2.7e-205 XP_011542761 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 8719 717.6 2.7e-205 XP_016866681 (OMIM: 605433) PREDICTED: kinesin-lik (1762) 5795 482.5 1.6e-134 NP_001099036 (OMIM: 605433) kinesin-like protein K (1770) 5795 482.5 1.6e-134 XP_016866679 (OMIM: 605433) PREDICTED: kinesin-lik (1784) 5746 478.6 2.4e-133 XP_016866677 (OMIM: 605433) PREDICTED: kinesin-lik (1797) 5744 478.4 2.7e-133 NP_071396 (OMIM: 605433) kinesin-like protein KIF1 (1805) 5744 478.4 2.7e-133 XP_016866680 (OMIM: 605433) PREDICTED: kinesin-lik (1771) 5539 461.9 2.5e-128 XP_016866682 (OMIM: 605433) PREDICTED: kinesin-lik (1694) 5200 434.6 3.8e-120 NP_001099038 (OMIM: 605433) kinesin-like protein K (1749) 4485 377.2 7.9e-103 NP_001099037 (OMIM: 605433) kinesin-like protein K (1757) 4485 377.2 7.9e-103 XP_016866678 (OMIM: 605433) PREDICTED: kinesin-lik (1792) 4485 377.2 8e-103 NP_006603 (OMIM: 603060,611302) kinesin-like prote (1103) 1469 134.5 5.4e-30 XP_005256481 (OMIM: 603060,611302) PREDICTED: kine (1103) 1469 134.5 5.4e-30 NP_904325 (OMIM: 118210,171300,256700,605995) kine (1153) 1458 133.7 1e-29 XP_016858496 (OMIM: 611279,616258) PREDICTED: kine (1459) 1456 133.6 1.4e-29 XP_011508537 (OMIM: 611279,616258) PREDICTED: kine (1524) 1456 133.6 1.4e-29 NP_055889 (OMIM: 118210,171300,256700,605995) kine (1770) 1458 133.8 1.4e-29 XP_016858495 (OMIM: 611279,616258) PREDICTED: kine (1605) 1456 133.6 1.5e-29 XP_011508535 (OMIM: 611279,616258) PREDICTED: kine (1620) 1456 133.6 1.5e-29 XP_011508534 (OMIM: 611279,616258) PREDICTED: kine (1648) 1456 133.6 1.5e-29 XP_016858494 (OMIM: 611279,616258) PREDICTED: kine (1648) 1456 133.6 1.5e-29 XP_011508533 (OMIM: 611279,616258) PREDICTED: kine (1648) 1456 133.6 1.5e-29 NP_055690 (OMIM: 611279,616258) kinesin-like prote (1648) 1456 133.6 1.5e-29 NP_004312 (OMIM: 201300,601255,610357,614213,61425 (1690) 1451 133.2 2.1e-29 XP_005247084 (OMIM: 201300,601255,610357,614213,61 (1698) 1451 133.2 2.1e-29 XP_016859879 (OMIM: 201300,601255,610357,614213,61 (1699) 1451 133.2 2.1e-29 NP_001307634 (OMIM: 201300,601255,610357,614213,61 (1699) 1451 133.2 2.1e-29 NP_001317218 (OMIM: 201300,601255,610357,614213,61 (1708) 1451 133.2 2.1e-29 NP_001317219 (OMIM: 201300,601255,610357,614213,61 (1724) 1451 133.2 2.1e-29 XP_016859877 (OMIM: 201300,601255,610357,614213,61 (1732) 1451 133.2 2.1e-29 XP_016859876 (OMIM: 201300,601255,610357,614213,61 (1733) 1451 133.2 2.1e-29 XP_006712668 (OMIM: 201300,601255,610357,614213,61 (1782) 1451 133.2 2.1e-29 NP_001230937 (OMIM: 201300,601255,610357,614213,61 (1791) 1451 133.3 2.2e-29 XP_005247081 (OMIM: 201300,601255,610357,614213,61 (1791) 1451 133.3 2.2e-29 XP_016859880 (OMIM: 201300,601255,610357,614213,61 (1799) 1451 133.3 2.2e-29 XP_005247079 (OMIM: 201300,601255,610357,614213,61 (1800) 1451 133.3 2.2e-29 XP_011509666 (OMIM: 201300,601255,610357,614213,61 (1800) 1451 133.3 2.2e-29 XP_016859875 (OMIM: 201300,601255,610357,614213,61 (1816) 1451 133.3 2.2e-29 XP_016859874 (OMIM: 201300,601255,610357,614213,61 (1824) 1451 133.3 2.2e-29 XP_016859873 (OMIM: 201300,601255,610357,614213,61 (1825) 1451 133.3 2.2e-29 XP_016859872 (OMIM: 201300,601255,610357,614213,61 (1825) 1451 133.3 2.2e-29 XP_011508538 (OMIM: 611279,616258) PREDICTED: kine (1157) 1072 102.6 2.3e-20 NP_001292721 (OMIM: 611279,616258) kinesin-like pr (1157) 1072 102.6 2.3e-20 >>NP_056069 (OMIM: 607350) kinesin-like protein KIF13B [ (1826 aa) initn: 12051 init1: 12051 opt: 12051 Z-score: 5254.3 bits: 985.5 E(85289): 0 Smith-Waterman score: 12051; 100.0% identity (100.0% similar) in 1826 aa overlap (1-1826:1-1826) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD PGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDI 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD RVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD LSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD PPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAP 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD GAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSG 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD KNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATN 1750 1760 1770 1780 1790 1800 1810 1820 pF1KSD LASLTAALAKADRSHKNPENRKSWAS :::::::::::::::::::::::::: NP_056 LASLTAALAKADRSHKNPENRKSWAS 1810 1820 >>XP_011542760 (OMIM: 607350) PREDICTED: kinesin-like pr (1826 aa) initn: 11142 init1: 11142 opt: 11228 Z-score: 4896.7 bits: 919.3 E(85289): 0 Smith-Waterman score: 11810; 97.7% identity (97.7% similar) in 1847 aa overlap (1-1826:1-1826) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KSD SSPNVNR---------------------LSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV ::::::: :::::::::::::::::::::::::::::::: XP_011 SSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD SRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKR 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD PSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPP ::::::: :::::::::::::::::::::::::::::::: XP_011 PSPLAHQ---------------------AQPEMGPDVLVQTMGAPALKICDKPAKVPSPP 1510 1520 1530 1540 1550 1560 1570 1580 1590 pF1KSD PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAP 1540 1550 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 pF1KSD EAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSF 1600 1610 1620 1630 1640 1650 1660 1670 1680 1690 1700 1710 pF1KSD SRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRY 1660 1670 1680 1690 1700 1710 1720 1730 1740 1750 1760 1770 pF1KSD VGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRST 1720 1730 1740 1750 1760 1770 1780 1790 1800 1810 1820 pF1KSD GLRLGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLRLGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS 1780 1790 1800 1810 1820 >>XP_005273515 (OMIM: 607350) PREDICTED: kinesin-like pr (1805 aa) initn: 9747 init1: 9747 opt: 9827 Z-score: 4288.1 bits: 806.7 E(85289): 0 Smith-Waterman score: 11862; 98.8% identity (98.8% similar) in 1826 aa overlap (1-1826:1-1805) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD PGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDI :::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQ-------------- 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KSD RVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -------AQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSP 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 pF1KSD LSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEE 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 pF1KSD PPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAP 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KSD GAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSG 1660 1670 1680 1690 1700 1710 1750 1760 1770 1780 1790 1800 pF1KSD KNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATN 1720 1730 1740 1750 1760 1770 1810 1820 pF1KSD LASLTAALAKADRSHKNPENRKSWAS :::::::::::::::::::::::::: XP_005 LASLTAALAKADRSHKNPENRKSWAS 1780 1790 1800 >>XP_011542759 (OMIM: 607350) PREDICTED: kinesin-like pr (1847 aa) initn: 9085 init1: 9085 opt: 9159 Z-score: 3997.7 bits: 753.0 E(85289): 6.2e-216 Smith-Waterman score: 11999; 98.9% identity (98.9% similar) in 1847 aa overlap (1-1826:1-1847) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KSD SSPNVNR---------------------LSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV ::::::: :::::::::::::::::::::::::::::::: XP_011 SSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD SRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKR 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD PSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPP 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KSD PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAP 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KSD EAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSF 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KSD SRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRY 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KSD VGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRST 1750 1760 1770 1780 1790 1800 1780 1790 1800 1810 1820 pF1KSD GLRLGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLRLGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS 1810 1820 1830 1840 >>XP_016868746 (OMIM: 607350) PREDICTED: kinesin-like pr (1490 aa) initn: 9431 init1: 9082 opt: 9088 Z-score: 3968.1 bits: 747.2 E(85289): 2.7e-214 Smith-Waterman score: 9387; 98.6% identity (98.6% similar) in 1462 aa overlap (1-1441:1-1462) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KSD SSPNVNR---------------------LSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV ::::::: :::::::::::::::::::::::::::::::: XP_016 SSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTV 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD SRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKR :::::::::::::::::::::: XP_016 SRGIAPAPALSVSPQNNHSPDPARAPHHGAVSQPGHQGDQDGGGSAGDGP 1450 1460 1470 1480 1490 >>XP_011542763 (OMIM: 607350) PREDICTED: kinesin-like pr (1783 aa) initn: 8645 init1: 8645 opt: 8719 Z-score: 3806.7 bits: 717.6 E(85289): 2.7e-205 Smith-Waterman score: 11559; 98.8% identity (98.8% similar) in 1783 aa overlap (65-1826:1-1783) 40 50 60 70 80 90 pF1KSD VILNPVNTNLSKGDARGQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDG :::::::::::::::::::::::::::::: XP_011 MDESVKEKYAGQDIVFKCLGENILQNAFDG 10 20 30 100 110 120 130 140 150 pF1KSD YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI 760 770 780 790 800 810 880 890 900 910 920 930 pF1KSD LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI 820 830 840 850 860 870 940 950 960 970 980 990 pF1KSD TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KSD ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KSD GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KSD SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KSD LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KSD PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KSD IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 pF1KSD TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNR---------------------LSGSRQ ::::::::::::::::::::::::::::::::: :::::: XP_011 TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQ 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KSD DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KSD VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KSD PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KSD STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE 1540 1550 1560 1570 1580 1590 1640 1650 1660 1670 1680 1690 pF1KSD RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE 1600 1610 1620 1630 1640 1650 1700 1710 1720 1730 1740 1750 pF1KSD ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR 1660 1670 1680 1690 1700 1710 1760 1770 1780 1790 1800 1810 pF1KSD CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR 1720 1730 1740 1750 1760 1770 1820 pF1KSD SHKNPENRKSWAS ::::::::::::: XP_011 SHKNPENRKSWAS 1780 >>XP_011542762 (OMIM: 607350) PREDICTED: kinesin-like pr (1783 aa) initn: 8645 init1: 8645 opt: 8719 Z-score: 3806.7 bits: 717.6 E(85289): 2.7e-205 Smith-Waterman score: 11559; 98.8% identity (98.8% similar) in 1783 aa overlap (65-1826:1-1783) 40 50 60 70 80 90 pF1KSD VILNPVNTNLSKGDARGQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDG :::::::::::::::::::::::::::::: XP_011 MDESVKEKYAGQDIVFKCLGENILQNAFDG 10 20 30 100 110 120 130 140 150 pF1KSD YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI 760 770 780 790 800 810 880 890 900 910 920 930 pF1KSD LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI 820 830 840 850 860 870 940 950 960 970 980 990 pF1KSD TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KSD ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KSD GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KSD SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KSD LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KSD PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KSD IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 pF1KSD TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNR---------------------LSGSRQ ::::::::::::::::::::::::::::::::: :::::: XP_011 TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQ 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KSD DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KSD VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KSD PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KSD STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE 1540 1550 1560 1570 1580 1590 1640 1650 1660 1670 1680 1690 pF1KSD RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE 1600 1610 1620 1630 1640 1650 1700 1710 1720 1730 1740 1750 pF1KSD ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR 1660 1670 1680 1690 1700 1710 1760 1770 1780 1790 1800 1810 pF1KSD CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR 1720 1730 1740 1750 1760 1770 1820 pF1KSD SHKNPENRKSWAS ::::::::::::: XP_011 SHKNPENRKSWAS 1780 >>XP_011542761 (OMIM: 607350) PREDICTED: kinesin-like pr (1783 aa) initn: 8645 init1: 8645 opt: 8719 Z-score: 3806.7 bits: 717.6 E(85289): 2.7e-205 Smith-Waterman score: 11559; 98.8% identity (98.8% similar) in 1783 aa overlap (65-1826:1-1783) 40 50 60 70 80 90 pF1KSD VILNPVNTNLSKGDARGQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDG :::::::::::::::::::::::::::::: XP_011 MDESVKEKYAGQDIVFKCLGENILQNAFDG 10 20 30 100 110 120 130 140 150 pF1KSD YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELK 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLN 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTF 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVD 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYE 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKAN 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDV 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKI 760 770 780 790 800 810 880 890 900 910 920 930 pF1KSD LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNI 820 830 840 850 860 870 940 950 960 970 980 990 pF1KSD TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQ 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KSD ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSV 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KSD GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLV 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KSD SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIF 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KSD LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGC 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KSD PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSS 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KSD IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 pF1KSD TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNR---------------------LSGSRQ ::::::::::::::::::::::::::::::::: :::::: XP_011 TLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNRVSVWNQALCCAWDFSPLLFSWLSGSRQ 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KSD DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNP 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KSD VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMG 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KSD PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSV 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KSD STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRE 1540 1550 1560 1570 1580 1590 1640 1650 1660 1670 1680 1690 pF1KSD RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEE 1600 1610 1620 1630 1640 1650 1700 1710 1720 1730 1740 1750 pF1KSD ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFR 1660 1670 1680 1690 1700 1710 1760 1770 1780 1790 1800 1810 pF1KSD CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADR 1720 1730 1740 1750 1760 1770 1820 pF1KSD SHKNPENRKSWAS ::::::::::::: XP_011 SHKNPENRKSWAS 1780 >>XP_016866681 (OMIM: 605433) PREDICTED: kinesin-like pr (1762 aa) initn: 5467 init1: 2694 opt: 5795 Z-score: 2536.3 bits: 482.5 E(85289): 1.6e-134 Smith-Waterman score: 6152; 58.3% identity (80.4% similar) in 1708 aa overlap (1-1678:1-1683) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :.:.:::::::.::::::: .:.:::::....:...:.: .: ..:. : :::::.:. XP_016 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGE-RKPPKVFAFDY 10 20 30 40 50 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::: :::::..:::::::.::..::.:::::::::::::::::..::: :.: XP_016 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG ::::::: .::.: . :.:: :.::::::::::::::::::::::::::.::::::.::: XP_016 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::.:::::..:::::::::::::::::::::::::::::::.: .:.::::..:: XP_016 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN .:::::.:.::::::::::..::::::.::::::::::::::::::::.::::.:::.:. XP_016 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN ::::::::::::::::.:::::.:.:.::.:::::::.:::::::::::::.:::::::: XP_016 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::..::.::::::::::::..:::::.::::..::::::::.:.::::::::::::: XP_016 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD ::::::.::::.::::. ::::::::::.:::::::::::::::::::.:: .:. .::: XP_016 IAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKDHTRVGADTSQD 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF ::: :.:: :.:: :::.:.:.: :::..:.:. :::. : : :: ::::::::::::: XP_016 IQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFF 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :.::::.:.. : ....:.. . :.: ..::.::: ..:::.::::: ::. XP_016 RINLPKRKRR------DWLKDFEKETGPPEHDLD--AASEASSEPDYNYEFAQMEVIMKT 540 550 560 570 580 590 610 620 630 640 650 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSM-DRFSF :.::::.:.... ::.:. ::::::::.::::::.::::::..:::..: : ::... XP_016 LNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAY 600 610 620 630 640 650 660 670 680 690 700 710 pF1KSD HSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQI : .:::.. ::::::. . .:: .::::.:::: ::::::..:::..: :.:.::::: XP_016 SSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KSD PASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPV ::..:.::::::...::::::::::::. :.:..:::.:.:.::::::::::: . XP_016 PAANLSANRKRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAK- 720 730 740 750 760 770 780 790 800 810 820 830 pF1KSD IRSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMR : : ::.::::. ::::.:::::::::: :: :::::::::::.:.::::::::::::: XP_016 -RLYGKRGDPFYEAQENHNLIGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMR 780 790 800 810 820 840 850 860 870 880 pF1KSD LSGDVGERI-----------AGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFV ..: : ::. .:. ::.. : : . .::.: ::: .::::: .::.:: XP_016 VTGAVPERVVEDDSSENSSESGSLEVVDSSGEIIHRVKKLTCRVKIKEATGLPLNLSNFV 830 840 850 860 870 880 890 900 910 920 930 940 pF1KSD FCKYSFWDQQEPVIVAPEVDTS-SSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGAL ::.:.:::: : ...:: :: : ::. . :.:.::... ::.::.:.: .:.::: XP_016 FCQYTFWDQCESTVAAPVVDPEVPSPQSKDAQYTVTFSHCKDYVVNVTEEFLEFISDGAL 890 900 910 920 930 940 950 960 970 980 990 1000 pF1KSD AIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPV ::::.::. .. ..:.. ..::::.:.:::.::::..:.:..::: :: ::: : XP_016 AIEVWGHRCAG--NGSSIWEVDSLHAKTRTLHDRWNEVTRRIEMWISILELNELGEYAAV 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KSD EVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAP :. .:::: ::::::::::.:::::: :: ::.::::::: : ::::.:::: .: . XP_016 ELHQAKDVNTGGIFQLRQGHSRRVQVTVKPVQHSGTLPLMVEAILSVSIGCVTARSTKLQ 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTHETFHEEEED---MDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDA : .......:: :::::..::. .:..: .:: ::.::::.:..:. .: .:::::. XP_016 RGLDSYQRDDEDGDDMDSYQEEDLNCVRERWSDALIKRREYLDEQIKKVSNKTEKTEDDV 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KSD DREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSS .:::::.:. . ::::::::.::. :::::::::.: : :::::::::.::::::::.:. XP_016 EREAQLVEQWVGLTEERNAVLVPAPGSGIPGAPADWIPPPGMETHIPVLFLDLNADDLSA 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 pF1KSD QDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVD ...: :.:.: .. : :. .:: : :.:. : ::.: :::::.:: .:.: :: . XP_016 NEQLVGPHASGVNSILPKEHGSQFFYLPIIKHSDDEVSATASWDSSVHDSVHLNRVTPQN 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KSD ERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEI ::..:::..:::::::: :.::::::: .:....:.:.::: ...: .. . .::::.:: XP_016 ERIYLIVKTTVQLSHPAAMELVLRKRIAANIYNKQSFTQSLKRRISLKNIFYSCGVTYEI 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KSD VSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVA :::::. .. .:.::.:: .:: :: ...:.:.::::: :.:: :::.:.:.:::: :. XP_016 VSNIPKATEEIEDRETLALLAARSENEGTSDGETYIEKYTRGVLQVENILSLERLRQAVT 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KSD VKEQLTGKGKLSRRSISSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVS-RGI ::: :. :.. :::.:.:::. .:.:: :: : ..:: :.: :.:. . : . . XP_016 VKEALSTKARHIRRSLSTPNVHNVSSSRPDL--SGFDEDDKGWPENQLDMSDYSSSYQDV 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 pF1KSD APAPALSV-SPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSP : .: ::. :. . . : . ..: :.: :: ::..: :.::..:.. :: XP_016 ACYGTLPRDSPRRNKEGCTSETPHALT-VSPFKAFSPQPPKFFKPLMPVKEEHK-KR--- 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KSD LAHQPVPRIMVQSASPDIRVTRMEEAQPEM---GPDVLVQTMGAPALKICDKPAKVPSPP .: . : .. : : . . ...: . .. : : :. . . . . : XP_016 IALEARP-LLSQEDSEE-EENELEAINRKLISSQPYVPVEFADFSVYNASLENREWFSSK 1490 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 pF1KSD PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPG-SMPTA .. . : :.. .: . : .:::::::.:.::::: . :. :.. . . : XP_016 VDLSNSRVLEK-EVSRSPTT--SSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDA 1540 1550 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 pF1KSD PEAEPEAP-ISHPPPPTAVP--AEEPPG---PQQLVSPGRERPDLEAPAPGSPFRVRRVR .: .: . : :.. .: : . .: : .: : .:.: .. XP_016 DSTEHSTPSLVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNS 1600 1610 1620 1630 1640 1650 1660 1670 1680 1690 1700 1710 pF1KSD ASELR--SFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVG : : : :.. : : :.: : XP_016 KSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNILEDHSFTEFMGVSEGKDFDGL 1660 1670 1680 1690 1700 1710 >>NP_001099036 (OMIM: 605433) kinesin-like protein KIF13 (1770 aa) initn: 5467 init1: 2694 opt: 5795 Z-score: 2536.3 bits: 482.5 E(85289): 1.6e-134 Smith-Waterman score: 6152; 58.3% identity (80.4% similar) in 1708 aa overlap (1-1678:1-1683) 10 20 30 40 50 60 pF1KSD MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH :.:.:::::::.::::::: .:.:::::....:...:.: .: ..:. : :::::.:. NP_001 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGE-RKPPKVFAFDY 10 20 30 40 50 70 80 90 100 110 120 pF1KSD CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP :::::::: :::::..:::::::.::..::.:::::::::::::::::..::: :.: NP_001 CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG ::::::: .::.: . :.:: :.::::::::::::::::::::::::::.::::::.::: NP_001 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG :::::::.:::::..:::::::::::::::::::::::::::::::.: .:.::::..:: NP_001 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN .:::::.:.::::::::::..::::::.::::::::::::::::::::.::::.:::.:. NP_001 NSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN ::::::::::::::::.:::::.:.:.::.:::::::.:::::::::::::.:::::::: NP_001 KFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVN 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE :::::..::.::::::::::::..:::::.::::..::::::::.:.::::::::::::: NP_001 EDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KSD IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD ::::::.::::.::::. ::::::::::.:::::::::::::::::::.:: .:. .::: NP_001 IAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKDHTRVGADTSQD 420 430 440 450 460 470 490 500 510 520 530 540 pF1KSD IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF ::: :.:: :.:: :::.:.:.: :::..:.:. :::. : : :: ::::::::::::: NP_001 IQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFF 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA :.::::.:.. : ....:.. . :.: ..::.::: ..:::.::::: ::. NP_001 RINLPKRKRR------DWLKDFEKETGPPEHDLD--AASEASSEPDYNYEFAQMEVIMKT 540 550 560 570 580 590 610 620 630 640 650 pF1KSD LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSM-DRFSF :.::::.:.... ::.:. ::::::::.::::::.::::::..:::..: : ::... NP_001 LNSNDPVQNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAY 600 610 620 630 640 650 660 670 680 690 700 710 pF1KSD HSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQI : .:::.. ::::::. . .:: .::::.:::: ::::::..:::..: :.:.::::: NP_001 SSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KSD PASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPV ::..:.::::::...::::::::::::. :.:..:::.:.:.::::::::::: . NP_001 PAANLSANRKRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAK- 720 730 740 750 760 770 780 790 800 810 820 830 pF1KSD IRSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMR : : ::.::::. ::::.:::::::::: :: :::::::::::.:.::::::::::::: NP_001 -RLYGKRGDPFYEAQENHNLIGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMR 780 790 800 810 820 840 850 860 870 880 pF1KSD LSGDVGERI-----------AGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFV ..: : ::. .:. ::.. : : . .::.: ::: .::::: .::.:: NP_001 VTGAVPERVVEDDSSENSSESGSLEVVDSSGEIIHRVKKLTCRVKIKEATGLPLNLSNFV 830 840 850 860 870 880 890 900 910 920 930 940 pF1KSD FCKYSFWDQQEPVIVAPEVDTS-SSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGAL ::.:.:::: : ...:: :: : ::. . :.:.::... ::.::.:.: .:.::: NP_001 FCQYTFWDQCESTVAAPVVDPEVPSPQSKDAQYTVTFSHCKDYVVNVTEEFLEFISDGAL 890 900 910 920 930 940 950 960 970 980 990 1000 pF1KSD AIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPV ::::.::. .. ..:.. ..::::.:.:::.::::..:.:..::: :: ::: : NP_001 AIEVWGHRCAG--NGSSIWEVDSLHAKTRTLHDRWNEVTRRIEMWISILELNELGEYAAV 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KSD EVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAP :. .:::: ::::::::::.:::::: :: ::.::::::: : ::::.:::: .: . NP_001 ELHQAKDVNTGGIFQLRQGHSRRVQVTVKPVQHSGTLPLMVEAILSVSIGCVTARSTKLQ 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD RTHETFHEEEED---MDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDA : .......:: :::::..::. .:..: .:: ::.::::.:..:. .: .:::::. NP_001 RGLDSYQRDDEDGDDMDSYQEEDLNCVRERWSDALIKRREYLDEQIKKVSNKTEKTEDDV 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KSD DREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSS .:::::.:. . ::::::::.::. :::::::::.: : :::::::::.::::::::.:. NP_001 EREAQLVEQWVGLTEERNAVLVPAPGSGIPGAPADWIPPPGMETHIPVLFLDLNADDLSA 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 pF1KSD QDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVD ...: :.:.: .. : :. .:: : :.:. : ::.: :::::.:: .:.: :: . NP_001 NEQLVGPHASGVNSILPKEHGSQFFYLPIIKHSDDEVSATASWDSSVHDSVHLNRVTPQN 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KSD ERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEI ::..:::..:::::::: :.::::::: .:....:.:.::: ...: .. . .::::.:: NP_001 ERIYLIVKTTVQLSHPAAMELVLRKRIAANIYNKQSFTQSLKRRISLKNIFYSCGVTYEI 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KSD VSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVA :::::. .. .:.::.:: .:: :: ...:.:.::::: :.:: :::.:.:.:::: :. NP_001 VSNIPKATEEIEDRETLALLAARSENEGTSDGETYIEKYTRGVLQVENILSLERLRQAVT 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KSD VKEQLTGKGKLSRRSISSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVS-RGI ::: :. :.. :::.:.:::. .:.:: :: : ..:: :.: :.:. . : . . NP_001 VKEALSTKARHIRRSLSTPNVHNVSSSRPDL--SGFDEDDKGWPENQLDMSDYSSSYQDV 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 pF1KSD APAPALSV-SPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSP : .: ::. :. . . : . ..: :.: :: ::..: :.::..:.. :: NP_001 ACYGTLPRDSPRRNKEGCTSETPHALT-VSPFKAFSPQPPKFFKPLMPVKEEHK-KR--- 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KSD LAHQPVPRIMVQSASPDIRVTRMEEAQPEM---GPDVLVQTMGAPALKICDKPAKVPSPP .: . : .. : : . . ...: . .. : : :. . . . . : NP_001 IALEARP-LLSQEDSEE-EENELEAINRKLISSQPYVPVEFADFSVYNASLENREWFSSK 1490 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 pF1KSD PVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPG-SMPTA .. . : :.. .: . : .:::::::.:.::::: . :. :.. . . : NP_001 VDLSNSRVLEK-EVSRSPTT--SSITSGYFSHSASNATLSDMVVPSSDSSDQLAIQTKDA 1540 1550 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 pF1KSD PEAEPEAP-ISHPPPPTAVP--AEEPPG---PQQLVSPGRERPDLEAPAPGSPFRVRRVR .: .: . : :.. .: : . .: : .: : .:.: .. NP_001 DSTEHSTPSLVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSPSSQSIPEKNS 1600 1610 1620 1630 1640 1650 1660 1670 1680 1690 1700 1710 pF1KSD ASELR--SFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVG : : : :.. : : :.: : NP_001 KSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNILEDHSFTEFMGVSEGKDFDGL 1660 1670 1680 1690 1700 1710 1826 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:26:38 2016 done: Thu Nov 3 02:26:41 2016 Total Scan time: 20.390 Total Display time: 0.930 Function used was FASTA [36.3.4 Apr, 2011]