FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0640, 585 aa 1>>>pF1KSDA0640 585 - 585 aa - 585 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.2242+/-0.00146; mu= -16.6286+/- 0.086 mean_var=598.1908+/-125.786, 0's: 0 Z-trim(110.9): 35 B-trim: 84 in 1/51 Lambda= 0.052439 statistics sampled from 11944 (11957) to 11944 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.367), width: 16 Scan time: 3.520 The best scores are: opt bits E(32554) CCDS31426.1 SWAP70 gene_id:23075|Hs108|chr11 ( 585) 3826 305.0 1.7e-82 CCDS73257.1 SWAP70 gene_id:23075|Hs108|chr11 ( 527) 2902 235.0 1.8e-61 CCDS4802.1 DEF6 gene_id:50619|Hs108|chr6 ( 631) 1719 145.6 1.7e-34 >>CCDS31426.1 SWAP70 gene_id:23075|Hs108|chr11 (585 aa) initn: 3826 init1: 3826 opt: 3826 Z-score: 1594.5 bits: 305.0 E(32554): 1.7e-82 Smith-Waterman score: 3826; 99.8% identity (100.0% similar) in 585 aa overlap (1-585:1-585) 10 20 30 40 50 60 pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD EKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS31 EKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH 490 500 510 520 530 540 550 560 570 580 pF1KSD HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE ::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE 550 560 570 580 >>CCDS73257.1 SWAP70 gene_id:23075|Hs108|chr11 (527 aa) initn: 2899 init1: 2899 opt: 2902 Z-score: 1217.2 bits: 235.0 E(32554): 1.8e-61 Smith-Waterman score: 3306; 89.9% identity (90.1% similar) in 585 aa overlap (1-585:1-527) 10 20 30 40 50 60 pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV :::::::::::::::::::: CCDS73 EGPVSNQGYMPYLNRFILEK---------------------------------------- 70 80 130 140 150 160 170 180 pF1KSD IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE :::::::::::::::::::::::::::::::::::::::::: CCDS73 ------------------IEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE 90 100 110 120 190 200 210 220 230 240 pF1KSD LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS 130 140 150 160 170 180 250 260 270 280 290 300 pF1KSD YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA 190 200 210 220 230 240 310 320 330 340 350 360 pF1KSD IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK 250 260 270 280 290 300 370 380 390 400 410 420 pF1KSD KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR 310 320 330 340 350 360 430 440 450 460 470 480 pF1KSD ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA 370 380 390 400 410 420 490 500 510 520 530 540 pF1KSD EKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS73 EKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH 430 440 450 460 470 480 550 560 570 580 pF1KSD HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE ::::::::::::::::::::::::::::::::::::::::::::: CCDS73 HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE 490 500 510 520 >>CCDS4802.1 DEF6 gene_id:50619|Hs108|chr6 (631 aa) initn: 1707 init1: 632 opt: 1719 Z-score: 732.6 bits: 145.6 E(32554): 1.7e-34 Smith-Waterman score: 1719; 45.7% identity (76.4% similar) in 588 aa overlap (3-579:2-583) 10 20 30 40 50 60 pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD .:..::::.::.:::::: ..:::::::::::::::: :::..::::::::::::::: CCDS48 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDD 10 20 30 40 50 70 80 90 100 110 pF1KSD EGPVSNQGYMPYLNRFILEKVQDN-FDKIEFNRMCWTLCVKKNL---TKNPLLITEEDAF .::::.::::::::..::.::... : : .:...:::: .::: ... .....::: CCDS48 DGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD KIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMG---GGWQQEQFEHYKINFDDSKNGL ..: .::::::::::::.: .:.::::::. .:. . . :.. . . .. .:: CCDS48 RLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD SAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFV :.:...::...:. .:. :.:.::::.::..::: :::::::. :.:: :.::.:::: CCDS48 SVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD LKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKK :.:. . :. ::. :.:.: : :: .:::: :::.:::.:.: :: ..:.:.:::: .. CCDS48 LQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTANRTYEMSASDTRQ 240 250 260 270 280 290 300 310 320 330 340 pF1KSD KQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELR----KKQLAEQEELERQMKELQAANE .::: ::. .:.: :. ::. .:.:.: : ... :..::: : ...:: .: CCDS48 RQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLR-LQQLQEEKE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KSD SKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKS : :::: ... ..: :::..: . . ::: . .:.. . : .:. .. : CCDS48 RKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKE 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD SELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHL : . ::..:::.: .:::::. : .::.:::.:: :.:::::: : .: . . CCDS48 EEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKE 420 430 440 450 460 470 470 480 490 500 510 520 pF1KSD EQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATN ::.. :. .. ::.::... . . ..::.:..::::.. .:..: :. : ...::..:.. CCDS48 EQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAST 480 490 500 510 520 530 530 540 550 560 570 580 pF1KSD KTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE ..: :. .. . :.. ::::.: : .:. . ..: : .:... : CCDS48 NVKHWNVQMNR---LMHPIEPGDKRP--VTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGN 540 550 560 570 580 590 CCDS48 RTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDPAPEN 600 610 620 630 585 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:27:21 2016 done: Thu Nov 3 02:27:21 2016 Total Scan time: 3.520 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]