Result of FASTA (omim) for
pF1KSDA0640
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0640, 585 aa
1>>>pF1KSDA0640 585 - 585 aa - 585 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.7359+/-0.000636; mu= -18.9255+/- 0.039
mean_var=736.1828+/-151.174, 0's: 0 Z-trim(118.8): 5 B-trim: 493 in 1/54
Lambda= 0.047270
statistics sampled from 32032 (32037) to 32032 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.376), width: 16
Scan time: 10.560
The best scores are: opt bits E(85289)
NP_055870 (OMIM: 604762) switch-associated protein ( 585) 3826 276.9 1.3e-73
NP_001284643 (OMIM: 604762) switch-associated prot ( 527) 2902 213.8 1.1e-54
XP_005252887 (OMIM: 604762) PREDICTED: switch-asso ( 436) 2829 208.7 3.2e-53
NP_071330 (OMIM: 610094) differentially expressed ( 631) 1719 133.2 2.5e-30
>>NP_055870 (OMIM: 604762) switch-associated protein 70 (585 aa)
initn: 3826 init1: 3826 opt: 3826 Z-score: 1442.5 bits: 276.9 E(85289): 1.3e-73
Smith-Waterman score: 3826; 99.8% identity (100.0% similar) in 585 aa overlap (1-585:1-585)
10 20 30 40 50 60
pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_055 EKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH
490 500 510 520 530 540
550 560 570 580
pF1KSD HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
:::::::::::::::::::::::::::::::::::::::::::::
NP_055 HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
550 560 570 580
>>NP_001284643 (OMIM: 604762) switch-associated protein (527 aa)
initn: 2899 init1: 2899 opt: 2902 Z-score: 1102.4 bits: 213.8 E(85289): 1.1e-54
Smith-Waterman score: 3306; 89.9% identity (90.1% similar) in 585 aa overlap (1-585:1-527)
10 20 30 40 50 60
pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWV
::::::::::::::::::::
NP_001 EGPVSNQGYMPYLNRFILEK----------------------------------------
70 80
130 140 150 160 170 180
pF1KSD IFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------IEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIE
90 100 110 120
190 200 210 220 230 240
pF1KSD LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIIS
130 140 150 160 170 180
250 260 270 280 290 300
pF1KSD YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQA
190 200 210 220 230 240
310 320 330 340 350 360
pF1KSD IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRK
250 260 270 280 290 300
370 380 390 400 410 420
pF1KSD KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVR
310 320 330 340 350 360
430 440 450 460 470 480
pF1KSD ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA
370 380 390 400 410 420
490 500 510 520 530 540
pF1KSD EKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 EKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAH
430 440 450 460 470 480
550 560 570 580
pF1KSD HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
490 500 510 520
>>XP_005252887 (OMIM: 604762) PREDICTED: switch-associat (436 aa)
initn: 2829 init1: 2829 opt: 2829 Z-score: 1076.5 bits: 208.7 E(85289): 3.2e-53
Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (150-585:1-436)
120 130 140 150 160 170
pF1KSD VIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELI
::::::::::::::::::::::::::::::
XP_005 MGGGWQQEQFEHYKINFDDSKNGLSAWELI
10 20 30
180 190 200 210 220 230
pF1KSD ELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNII
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD SYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD AIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVR
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD KKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRV
220 230 240 250 260 270
420 430 440 450 460 470
pF1KSD RELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTE
280 290 300 310 320 330
480 490 500 510 520 530
pF1KSD AEKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATNKTKSWKDKVA
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_005 AEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVA
340 350 360 370 380 390
540 550 560 570 580
pF1KSD HHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
400 410 420 430
>>NP_071330 (OMIM: 610094) differentially expressed in F (631 aa)
initn: 1707 init1: 632 opt: 1719 Z-score: 665.5 bits: 133.2 E(85289): 2.5e-30
Smith-Waterman score: 1719; 45.7% identity (76.4% similar) in 588 aa overlap (3-579:2-583)
10 20 30 40 50 60
pF1KSD MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
.:..::::.::.:::::: ..:::::::::::::::: :::..:::::::::::::::
NP_071 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDD
10 20 30 40 50
70 80 90 100 110
pF1KSD EGPVSNQGYMPYLNRFILEKVQDN-FDKIEFNRMCWTLCVKKNL---TKNPLLITEEDAF
.::::.::::::::..::.::... : : .:...:::: .::: ... .....:::
NP_071 DGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD KIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMG---GGWQQEQFEHYKINFDDSKNGL
..: .::::::::::::.: .:.::::::. .:. . . :.. . . .. .::
NP_071 RLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD SAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFV
:.:...::...:. .:. :.:.::::.::..::: :::::::. :.:: :.::.::::
NP_071 SVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD LKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKK
:.:. . :. ::. :.:.: : :: .:::: :::.:::.:.: :: ..:.:.:::: ..
NP_071 LQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTANRTYEMSASDTRQ
240 250 260 270 280 290
300 310 320 330 340
pF1KSD KQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELR----KKQLAEQEELERQMKELQAANE
.::: ::. .:.: :. ::. .:.:.: : ... :..::: : ...:: .:
NP_071 RQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLR-LQQLQEEKE
300 310 320 330 340 350
350 360 370 380 390 400
pF1KSD SKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKS
: :::: ... ..: :::..: . . ::: . .:.. . : .:. .. :
NP_071 RKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKE
360 370 380 390 400 410
410 420 430 440 450 460
pF1KSD SELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHL
: . ::..:::.: .:::::. : .::.:::.:: :.:::::: : .: . .
NP_071 EEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKE
420 430 440 450 460 470
470 480 490 500 510 520
pF1KSD EQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEELELERKQALEQYEEVKKKLEMATN
::.. :. .. ::.::... . . ..::.:..::::.. .:..: :. : ...::..:..
NP_071 EQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAST
480 490 500 510 520 530
530 540 550 560 570 580
pF1KSD KTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
..: :. .. . :.. ::::.: : .:. . ..: : .:... :
NP_071 NVKHWNVQMNR---LMHPIEPGDKRP--VTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGN
540 550 560 570 580 590
NP_071 RTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDPAPEN
600 610 620 630
585 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:27:22 2016 done: Thu Nov 3 02:27:23 2016
Total Scan time: 10.560 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]