FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0642, 1320 aa 1>>>pF1KSDA0642 1320 - 1320 aa - 1320 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.0429+/-0.00117; mu= -9.8761+/- 0.070 mean_var=595.4297+/-122.630, 0's: 0 Z-trim(115.4): 130 B-trim: 105 in 1/54 Lambda= 0.052560 statistics sampled from 15845 (15951) to 15845 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.49), width: 16 Scan time: 6.070 The best scores are: opt bits E(32554) CCDS46542.1 GIGYF2 gene_id:26058|Hs108|chr2 (1320) 8875 689.2 1.9e-197 CCDS33401.1 GIGYF2 gene_id:26058|Hs108|chr2 (1299) 7501 585.0 4.3e-166 CCDS46543.1 GIGYF2 gene_id:26058|Hs108|chr2 (1293) 7436 580.1 1.3e-164 CCDS34708.1 GIGYF1 gene_id:64599|Hs108|chr7 (1035) 870 82.1 8.6e-15 >>CCDS46542.1 GIGYF2 gene_id:26058|Hs108|chr2 (1320 aa) initn: 8875 init1: 8875 opt: 8875 Z-score: 3658.3 bits: 689.2 E(32554): 1.9e-197 Smith-Waterman score: 8875; 100.0% identity (100.0% similar) in 1320 aa overlap (1-1320:1-1320) 10 20 30 40 50 60 pF1KSD MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQEH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTAS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWAS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD KLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD DTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD HSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY 1270 1280 1290 1300 1310 1320 >>CCDS33401.1 GIGYF2 gene_id:26058|Hs108|chr2 (1299 aa) initn: 7383 init1: 6178 opt: 7501 Z-score: 3095.3 bits: 585.0 E(32554): 4.3e-166 Smith-Waterman score: 8645; 98.3% identity (98.3% similar) in 1321 aa overlap (1-1320:1-1299) 10 20 30 40 50 60 pF1KSD MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 130 140 150 160 170 190 200 210 220 230 240 pF1KSD NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG :::::::::::::::::::::::::::::::::::::::: CCDS33 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 180 190 200 210 250 260 270 280 290 300 pF1KSD GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 280 290 300 310 320 330 370 380 390 400 410 pF1KSD GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: CCDS33 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KSD EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 400 410 420 430 440 450 480 490 500 510 520 530 pF1KSD SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 460 470 480 490 500 510 540 550 560 570 580 590 pF1KSD HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 520 530 540 550 560 570 600 610 620 630 640 650 pF1KSD PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 580 590 600 610 620 630 660 670 680 690 700 710 pF1KSD VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 640 650 660 670 680 690 720 730 740 750 760 770 pF1KSD SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 700 710 720 730 740 750 780 790 800 810 820 830 pF1KSD EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 760 770 780 790 800 810 840 850 860 870 880 890 pF1KSD ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 820 830 840 850 860 870 900 910 920 930 940 950 pF1KSD EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 880 890 900 910 920 930 960 970 980 990 1000 1010 pF1KSD QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KSD TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 pF1KSD SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1060 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 pF1KSD EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KSD GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KSD LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1240 1250 1260 1270 1280 1290 1320 pF1KSD Y : CCDS33 Y >>CCDS46543.1 GIGYF2 gene_id:26058|Hs108|chr2 (1293 aa) initn: 7383 init1: 6178 opt: 7436 Z-score: 3068.7 bits: 580.1 E(32554): 1.3e-164 Smith-Waterman score: 8580; 97.8% identity (97.8% similar) in 1321 aa overlap (1-1320:1-1293) 10 20 30 40 50 60 pF1KSD MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVG-- 130 140 150 160 170 190 200 210 220 230 240 pF1KSD NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG :::::::::::::::::::::::::::::::::::::::: CCDS46 --------------------RPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG 180 190 200 210 250 260 270 280 290 300 pF1KSD GWRLAGSRRDGERWRPHSPDGPRSAGWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI ::::::::::::::::::: ::::::::::::::::::::::::::::::::::: CCDS46 GWRLAGSRRDGERWRPHSP------GWREHMERRRRFEFDFRDRDDERGYRRVRSGSGSI 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSE 280 290 300 310 320 330 370 380 390 400 410 pF1KSD GSHNEEAKEPDKTNKKEGEKTDRVGV-ASEETPQTSSSSARPGTPSDHQSQEASQFERKD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: CCDS46 GSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKD 340 350 360 370 380 390 420 430 440 450 460 470 pF1KSD EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNP 400 410 420 430 440 450 480 490 500 510 520 530 pF1KSD SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQDSALDDERLASKLQE 460 470 480 490 500 510 540 550 560 570 580 590 pF1KSD HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWFQAGYFTMSLLVKRACDESFQ 520 530 540 550 560 570 600 610 620 630 640 650 pF1KSD PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQ 580 590 600 610 620 630 660 670 680 690 700 710 pF1KSD VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTA 640 650 660 670 680 690 720 730 740 750 760 770 pF1KSD SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ 700 710 720 730 740 750 780 790 800 810 820 830 pF1KSD EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 760 770 780 790 800 810 840 850 860 870 880 890 pF1KSD ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 820 830 840 850 860 870 900 910 920 930 940 950 pF1KSD EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 880 890 900 910 920 930 960 970 980 990 1000 1010 pF1KSD QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 940 950 960 970 980 990 1020 1030 1040 1050 1060 1070 pF1KSD TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWA 1000 1010 1020 1030 1040 1050 1080 1090 1100 1110 1120 1130 pF1KSD SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1060 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 pF1KSD EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYL 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KSD GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHST 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KSD LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDD 1240 1250 1260 1270 1280 1290 1320 pF1KSD Y : CCDS46 Y >>CCDS34708.1 GIGYF1 gene_id:64599|Hs108|chr7 (1035 aa) initn: 2361 init1: 713 opt: 870 Z-score: 379.0 bits: 82.1 E(32554): 8.6e-15 Smith-Waterman score: 2973; 42.8% identity (61.8% similar) in 1363 aa overlap (1-1320:1-1035) 10 20 30 40 50 60 pF1KSD MAAETQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDNKIPS ::::: ::::::::::::.:::..::: :::.::::::::::::::::::..:.::.: CCDS34 MAAET--LNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPE 10 20 30 40 50 70 80 90 100 110 120 pF1KSD DLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAAVLRLTGRGGGGTVVGAPRGR .: :::: .::.::: :::: :.:::::::::.::::.::::: :.:.: ..:. ::: CCDS34 ELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD SSSRGRGRGRGECGFYQRSFDEVEGVFGRGGGREMHRSQSWEERGDRRFEKPGRKDVGKK .:.:.::::::. :::::..: .:.:::. ::..:::::..::.::::: .:.: CCDS34 GSTRSRGRGRGDSCFYQRSIEEGDGAFGRSP-REIQRSQSWDDRGERRFEKSARRD---- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD NGYYCMYSPVLLLGQPLCQGRPNFEEGGPTSVGRKHEFIRSESENWRIFREEQNGEDEDG : : .::::: .: ..: ::.::::: .::::. :.:.: CCDS34 -GARC-----------------GFEEGG---AGPRKEHARSDSENWRSLREEQE-EEEEG 180 190 200 210 250 260 270 280 pF1KSD GWRL-AGSRRDGERWRPHSPDG-PRSAGWREHMERRRRFEFDFR-DR-----DDERG--- .::: :: ::::.::: :::: ::::::::: ::::.::::.: :: .. :: CCDS34 SWRLGAGPRRDGDRWRSASPDGGPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGG 220 230 240 250 260 270 290 300 310 320 330 340 pF1KSD ---YRRVRSGSGSIDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMD :: :. : ...:.:.::::::.: .:::::::.::::: ::: :::::::::.: CCDS34 SSHLRRCRAPEG-FEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELD 280 290 300 310 320 330 350 360 370 380 390 400 pF1KSD FRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSD :. ..: :: ::: . :: :..... : :.. CCDS34 FQGLEEEEE--PSEGLE-------------------------EEGPEAGGKELTPLPPQE 340 350 360 410 420 430 440 450 460 pF1KSD HQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTA ..: : :. .:. : :: .: CCDS34 EKS----------------------------SSPSPLPTLG---------PLWGTNGDGD 370 380 470 480 490 500 510 520 pF1KSD SPLLILPPPVPNPSPTLRPVETPVVGAPGMGSVSTEP---DDEEGLKHLEQQAEKMVAYL :: . . .: .. .::.:: . : .:.::::::.:.:::.:: : CCDS34 ETAEKEPPAAEDD---IRGIQL----SPGVGSSAGPPGDLEDDEGLKHLQQEAEKLVASL 390 400 410 420 430 530 540 550 560 570 pF1KSD QDSALDDERLASKLQ----EHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEMAEWF :::.:..:.... .: .: : ....:: : : .::.::::::::::::..::::::: CCDS34 QDSSLEEEQFTAAMQTQGLRHSAAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWF 440 450 460 470 480 490 580 590 600 610 620 630 pF1KSD QAGYFTMSLLVKRACDESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELTA :::::.:::::::.:::.:::::...::::::::.:::.::: .:..::::: .::::.: CCDS34 QAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAA 500 510 520 530 540 550 640 650 660 670 680 pF1KSD --LYQ-MQHLQYQQFLIQQQYAQVLAQQQKAALSS----------QQQQQLALLLQQFQT ::: .:: :. :.. ..: : : ..::::.. ::::::. .:::.:. CCDS34 AALYQQLQHQQFLQLVSSRQLPQC-ALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQA 560 570 580 590 600 610 690 700 710 720 730 740 pF1KSD LKM-RISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALE :: : .:::..:...::.::::.: .:... .::. . :. :.::.:....: :: :: CCDS34 LKPPRGGDQNLLPTMSRSLSVPDSGRLWDVHTSASSQSGGEA-SLWDIPINSSTQGPILE 620 630 640 650 660 670 750 760 770 780 790 800 pF1KSD QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE ::: .: :::::.:.:::::::::::.:: :::: ::::...:.:::: CCDS34 QLQLQHKF------QERREVELRAKREEEERKRREEKRRQQ------QQEEQKRRQEEEE 680 690 700 710 720 810 820 830 840 850 860 pF1KSD LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE : :::. CCDS34 LFRRKHV----------------------------------------------------- 730 870 880 890 900 910 920 pF1KSD EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE ::.::. CCDS34 ----------------------------------------------RQQELL-------- 930 940 950 960 970 980 pF1KSD ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ :. ::::: . .: . . : : CCDS34 -LKLLQQQQA------VPVPPAPS-----------SPPPL-------------------- 740 750 760 990 1000 1010 1020 1030 1040 pF1KSD RRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQ :....: . . :.:::.: : ::..:: .. CCDS34 ------------------------WAGLAKQGLSMKTLLELQLEGERQLHKQPPPRE--- 770 780 790 1050 1060 1070 1080 1090 1100 pF1KSD QPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTK---NSNMGFWDD : ::. .: .... :...:.: :::.:. .. .:.. : . .:..:.:.: CCDS34 -PARAQAPNH---RVQL-----GGLGTAPLNQWVSE-AGPLWGGPDKSGGGSSGLGLWED 800 810 820 830 840 1110 1120 1130 1140 1150 pF1KSD AVKEVGP--RNSTNKN-KNNASLSKSVG-VSNRQ-NKKVEEEEKLLKLFQGVNKAQDGFT . : : :. :: ... ::: : . .:.: ::.:::::::::.::. . ::::: CCDS34 TPKSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFT 850 860 870 880 890 900 1160 1170 1180 1190 1200 1210 pF1KSD QWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSEAKEFAKQFLERRA ::::::::.:.....:::: :..::::::::.::::::. :::: :::::::::::::: CCDS34 QWCEQMLHTLSATGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRA 910 920 930 940 950 960 1220 1230 1240 1250 1260 1270 pF1KSD KQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFE ::::.::::::: .: .. ..:...::.:.: ... CCDS34 KQKASQQRQQQQ---------------------EAW-LSSASLQTAFQANHS----TKLG 970 980 990 1280 1290 1300 1310 1320 pF1KSD AVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLDDY ...: :.. :...:::.::.:...:: ::::..::: CCDS34 PGEGSKAKRRALMLHSDPSILGYSLHGSS-----GEIESVDDY 1000 1010 1020 1030 1320 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:35:10 2016 done: Thu Nov 3 18:35:11 2016 Total Scan time: 6.070 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]