FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0645, 1572 aa 1>>>pF1KSDA0645 1572 - 1572 aa - 1572 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9065+/-0.00105; mu= 15.8985+/- 0.063 mean_var=92.2247+/-18.023, 0's: 0 Z-trim(105.4): 22 B-trim: 6 in 1/49 Lambda= 0.133552 statistics sampled from 8413 (8424) to 8413 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.259), width: 16 Scan time: 4.770 The best scores are: opt bits E(32554) CCDS43006.1 DEPDC5 gene_id:9681|Hs108|chr22 (1572) 10626 2058.5 0 CCDS46692.1 DEPDC5 gene_id:9681|Hs108|chr22 (1594) 7302 1418.1 0 CCDS56229.1 DEPDC5 gene_id:9681|Hs108|chr22 (1503) 5790 1126.7 0 CCDS74849.1 DEPDC5 gene_id:9681|Hs108|chr22 (1603) 4844 944.5 0 CCDS43007.1 DEPDC5 gene_id:9681|Hs108|chr22 ( 559) 3697 723.4 5e-208 >>CCDS43006.1 DEPDC5 gene_id:9681|Hs108|chr22 (1572 aa) initn: 10626 init1: 10626 opt: 10626 Z-score: 11055.9 bits: 2058.5 E(32554): 0 Smith-Waterman score: 10626; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572) 10 20 30 40 50 60 pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW 1510 1520 1530 1540 1550 1560 1570 pF1KSD TSCLEKMHASAP :::::::::::: CCDS43 TSCLEKMHASAP 1570 >>CCDS46692.1 DEPDC5 gene_id:9681|Hs108|chr22 (1594 aa) initn: 7295 init1: 7295 opt: 7302 Z-score: 7594.5 bits: 1418.1 E(32554): 0 Smith-Waterman score: 10572; 98.6% identity (98.6% similar) in 1594 aa overlap (1-1572:1-1594) 10 20 30 40 50 60 pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 pF1KSD ---------------------VSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG ::::::::::::::::::::::::::::::::::::::: CCDS46 GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KSD FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KSD WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 pF1KSD DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP :::::::::::::::::::::::::::::::::: CCDS46 DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP 1570 1580 1590 >>CCDS56229.1 DEPDC5 gene_id:9681|Hs108|chr22 (1503 aa) initn: 9960 init1: 5790 opt: 5790 Z-score: 6020.5 bits: 1126.7 E(32554): 0 Smith-Waterman score: 9913; 94.4% identity (94.5% similar) in 1581 aa overlap (1-1572:1-1503) 10 20 30 40 50 60 pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE :::::::::::::::::::::::: CCDS56 FAPSRMPMKLTSNRRRWMHTFPVG------------------------------------ 610 620 670 680 690 700 710 720 pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS :::::::::::::::::: CCDS56 ------------------------------------------MNPRTQNKDSLEDSVSTS 630 640 730 740 750 760 770 pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE :::. ::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE 650 660 670 680 690 700 780 790 800 810 820 830 pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL 710 720 730 740 750 760 840 850 860 870 880 890 pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE 770 780 790 800 810 820 900 910 920 930 940 950 pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT 830 840 850 860 870 880 960 970 980 990 1000 1010 pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP 890 900 910 920 930 940 1020 1030 1040 1050 1060 1070 pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP 950 960 970 980 990 1000 1080 1090 1100 1110 1120 1130 pF1KSD TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS 1010 1020 1030 1040 1050 1060 1140 1150 1160 1170 1180 1190 pF1KSD SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ 1070 1080 1090 1100 1110 1120 1200 1210 1220 1230 1240 1250 pF1KSD TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG 1130 1140 1150 1160 1170 1180 1260 1270 1280 1290 1300 1310 pF1KSD VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA 1190 1200 1210 1220 1230 1240 1320 1330 1340 1350 1360 1370 pF1KSD LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV 1250 1260 1270 1280 1290 1300 1380 1390 1400 1410 1420 1430 pF1KSD QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP 1310 1320 1330 1340 1350 1360 1440 1450 1460 1470 1480 1490 pF1KSD ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG 1370 1380 1390 1400 1410 1420 1500 1510 1520 1530 1540 1550 pF1KSD QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN 1430 1440 1450 1460 1470 1480 1560 1570 pF1KSD RDNRLVTFWTSCLEKMHASAP ::::::::::::::::::::: CCDS56 RDNRLVTFWTSCLEKMHASAP 1490 1500 >>CCDS74849.1 DEPDC5 gene_id:9681|Hs108|chr22 (1603 aa) initn: 8160 init1: 4841 opt: 4844 Z-score: 5035.0 bits: 944.5 E(32554): 0 Smith-Waterman score: 10539; 98.0% identity (98.1% similar) in 1603 aa overlap (1-1572:1-1603) 10 20 30 40 50 60 pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS 670 680 690 700 710 720 730 740 750 760 770 pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE :::. ::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP 1030 1040 1050 1060 1070 1080 1080 1090 1100 pF1KSD TYMDSPRK----------------------VSVDQTATPMLDGTSLGICTGQSMDRGNSQ :::::::: :::::::::::::::::::::::::::::: CCDS74 TYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQ 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KSD TFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGL 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 1220 pF1KSD SPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKI 1210 1220 1230 1240 1250 1260 1230 1240 1250 1260 1270 1280 pF1KSD VTDKEPDRVAMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VTDKEPDRVAMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRP 1270 1280 1290 1300 1310 1320 1290 1300 1310 1320 1330 1340 pF1KSD ASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSL 1330 1340 1350 1360 1370 1380 1350 1360 1370 1380 1390 1400 pF1KSD NAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLF 1390 1400 1410 1420 1430 1440 1410 1420 1430 1440 1450 1460 pF1KSD IPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 IPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKP 1450 1460 1470 1480 1490 1500 1470 1480 1490 1500 1510 1520 pF1KSD QYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRS 1510 1520 1530 1540 1550 1560 1530 1540 1550 1560 1570 pF1KSD SATGDEKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP ::::::::::::::::::::::::::::::::::::::::::: CCDS74 SATGDEKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP 1570 1580 1590 1600 >>CCDS43007.1 DEPDC5 gene_id:9681|Hs108|chr22 (559 aa) initn: 3697 init1: 3697 opt: 3697 Z-score: 3848.2 bits: 723.4 E(32554): 5e-208 Smith-Waterman score: 3697; 99.6% identity (99.8% similar) in 558 aa overlap (1-558:1-558) 10 20 30 40 50 60 pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP :::::::::::::::. : CCDS43 HQYEVSSSLGYTSTREHLG 550 1572 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:28:49 2016 done: Thu Nov 3 02:28:50 2016 Total Scan time: 4.770 Total Display time: 0.460 Function used was FASTA [36.3.4 Apr, 2011]