FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0659, 1042 aa 1>>>pF1KSDA0659 1042 - 1042 aa - 1042 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4886+/-0.000391; mu= 11.7586+/- 0.024 mean_var=124.2708+/-24.938, 0's: 0 Z-trim(115.8): 6 B-trim: 43 in 2/54 Lambda= 0.115051 statistics sampled from 26554 (26560) to 26554 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.311), width: 16 Scan time: 12.560 The best scores are: opt bits E(85289) NP_006124 (OMIM: 614015) sn1-specific diacylglycer (1042) 6941 1164.1 0 XP_016873728 (OMIM: 614015) PREDICTED: sn1-specifi (1068) 5078 854.8 0 XP_016873727 (OMIM: 614015) PREDICTED: sn1-specifi (1068) 5078 854.8 0 XP_016873729 (OMIM: 614015) PREDICTED: sn1-specifi ( 638) 1874 322.9 3.5e-87 NP_001136408 (OMIM: 614016) sn1-specific diacylgly ( 543) 584 108.8 8.7e-23 NP_631918 (OMIM: 614016) sn1-specific diacylglycer ( 672) 583 108.7 1.2e-22 >>NP_006124 (OMIM: 614015) sn1-specific diacylglycerol l (1042 aa) initn: 6941 init1: 6941 opt: 6941 Z-score: 6228.3 bits: 1164.1 E(85289): 0 Smith-Waterman score: 6941; 100.0% identity (100.0% similar) in 1042 aa overlap (1-1042:1-1042) 10 20 30 40 50 60 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR 970 980 990 1000 1010 1020 1030 1040 pF1KSD TSTPTGHGASPAKQDELVISAR :::::::::::::::::::::: NP_006 TSTPTGHGASPAKQDELVISAR 1030 1040 >>XP_016873728 (OMIM: 614015) PREDICTED: sn1-specific di (1068 aa) initn: 5071 init1: 5071 opt: 5078 Z-score: 4556.9 bits: 854.8 E(85289): 0 Smith-Waterman score: 6879; 97.6% identity (97.6% similar) in 1068 aa overlap (1-1042:1-1068) 10 20 30 40 50 60 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 190 200 210 220 230 240 250 260 270 280 pF1KSD VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNS----------------- ::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSTNPLNSFTKFRSVWSWP 250 260 270 280 290 300 290 300 310 320 330 pF1KSD ---------QEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEMTEHFTRQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEV 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD TTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD KAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIF 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD QQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDP 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD VELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLE 790 800 810 820 830 840 820 830 840 850 860 870 pF1KSD RDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAA 850 860 870 880 890 900 880 890 900 910 920 930 pF1KSD ANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLY 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD CMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPL 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 pF1KSD SSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQDELVISAR :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQDELVISAR 1030 1040 1050 1060 >>XP_016873727 (OMIM: 614015) PREDICTED: sn1-specific di (1068 aa) initn: 5071 init1: 5071 opt: 5078 Z-score: 4556.9 bits: 854.8 E(85289): 0 Smith-Waterman score: 6879; 97.6% identity (97.6% similar) in 1068 aa overlap (1-1042:1-1068) 10 20 30 40 50 60 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 190 200 210 220 230 240 250 260 270 280 pF1KSD VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNS----------------- ::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSTNPLNSFTKFRSVWSWP 250 260 270 280 290 300 290 300 310 320 330 pF1KSD ---------QEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEMTEHFTRQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEV 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD TTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD KAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIF 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD QQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDP 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD VELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELLLLSTQERLAAELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLE 790 800 810 820 830 840 820 830 840 850 860 870 pF1KSD RDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAA 850 860 870 880 890 900 880 890 900 910 920 930 pF1KSD ANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLY 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD CMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPL 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 pF1KSD SSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQDELVISAR :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQDELVISAR 1030 1040 1050 1060 >>XP_016873729 (OMIM: 614015) PREDICTED: sn1-specific di (638 aa) initn: 1900 init1: 1871 opt: 1874 Z-score: 1686.2 bits: 322.9 E(85289): 3.5e-87 Smith-Waterman score: 3659; 94.9% identity (95.0% similar) in 584 aa overlap (1-558:1-584) 10 20 30 40 50 60 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 190 200 210 220 230 240 250 260 270 280 pF1KSD VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNS----------------- ::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSTNPLNSFTKFRSVWSWP 250 260 270 280 290 300 290 300 310 320 330 pF1KSD ---------QEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEMTEHFTRQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKE 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEV :::::::::::::::::::::::::::::::::::::: : .: XP_016 FVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKMRGWLGFQPLASPEIQQFHVIC 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD TTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN XP_016 PWHLIGRLATVHLSHCLFSGGSSWGPPNASPSRSCLRR 610 620 630 >>NP_001136408 (OMIM: 614016) sn1-specific diacylglycero (543 aa) initn: 888 init1: 337 opt: 584 Z-score: 530.1 bits: 108.8 E(85289): 8.7e-23 Smith-Waterman score: 725; 34.2% identity (62.9% similar) in 412 aa overlap (305-686:144-542) 280 290 300 310 320 330 pF1KSD TKYLDLKNSQEMLRYKEVCYYMLFALAAYGW-PMYLMRKPACGLCQLARSCSCCLCP--- : : : : : . . . : . : NP_001 LGAAWVADGVQCDRTVVNGIIATVVVRTQIWCPATLRRASPCFISNRTISGTTKSLPRWS 120 130 140 150 160 170 340 350 360 370 380 pF1KSD ARPRFAPGVTIEEDNCCGCNAIAIRRHFLD----ENMTAVDIVYTSCHDAVYETPFYVAV : :. ::. . . .. . :: . .. :....: :: ::: :: ::. NP_001 AMPQGAPSCRSRTTDYDLVGGDQLNCHFGSILHTTGLQYRDFIHVSFHDKVYELPFLVAL 180 190 200 210 220 230 390 400 410 420 430 440 pF1KSD DHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQE :: :..::...:::.: .:.::::....: : :: . :.:::. .:.:. ..: .. NP_001 DHRKESVVVAVRGTMSLQDVLTDLSAESEVLDVECEVQDRLAHKGISQAARYVYQRLIND 240 250 260 270 280 290 450 460 470 480 490 500 pF1KSD MVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSE .:::::. . .: :..::::::.:.::.:. .:: :: ..:.:.::: :: :. NP_001 GILSQAFS-----IAPEYRLVIVGHSLGGGAAALLATMLRAAYPQVRCYAFSPPRGLWSK 300 310 320 330 340 510 520 530 540 550 pF1KSD DAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIV--------- .:::. :....:::::..::.....:: ..:..: :. . .:::..:.. NP_001 ALQEYSQSFIVSLVLGKDVIPRLSVTNLEDLKRRILRVVAHCNKPKYKILLHGLWYELFG 350 360 370 380 390 400 560 570 580 590 600 pF1KSD GATKCIPKSELP---EEVEVTTLAS-----TRLWT----HPSDLTIALSAS-TPLYPPGR : . .: .:: .:: . : . :: :. :: . : . ::::::: NP_001 GNPNNLP-TELDGGDQEVLTQPLLGEQSLLTR-WSPAYSFSSDSPLDSSPKYPPLYPPGR 410 420 430 440 450 460 610 620 630 640 650 660 pF1KSD IIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLNKVLE :::. .. . . :: . : : :. . :....:.: :: .:.: ..:..:..:. NP_001 IIHLQEEGASGRFGCCSAAH--YSAKWSHEAEFSKILIGPKMLTDHMPDILMRALDSVVS 470 480 490 500 510 520 670 680 690 700 710 720 pF1KSD NYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRNSSVR . ..: .: :: ..: NP_001 D----RAACVSCPAQGVSSVDVA 530 540 >-- initn: 261 init1: 229 opt: 266 Z-score: 244.9 bits: 56.0 E(85289): 6.7e-07 Smith-Waterman score: 266; 33.1% identity (70.4% similar) in 142 aa overlap (1-140:1-139) 10 20 30 40 50 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLN-LVDHG :::.:.: :::...:::::.:..: ..... :.. ... . :.. . :. . :.. NP_001 MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWI--GILTLYLMHRGKLDCAGGALLSSY 10 20 30 40 50 60 70 80 90 100 110 pF1KSD RGYLGILLSCMIAEM-AIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVW : :::. .: . ::. .:::: : :: ::. .::.:::.. :...: .: .: NP_001 LIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLR ... ..:. ..... .:: NP_001 VADG-VQCDRTVVNGIIATVVVRTQIWCPATLRRASPCFISNRTISGTTKSLPRWSAMPQ 120 130 140 150 160 170 >>NP_631918 (OMIM: 614016) sn1-specific diacylglycerol l (672 aa) initn: 1195 init1: 337 opt: 583 Z-score: 527.8 bits: 108.7 E(85289): 1.2e-22 Smith-Waterman score: 1310; 34.6% identity (63.3% similar) in 712 aa overlap (1-686:1-671) 10 20 30 40 50 pF1KSD MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLN-LVDHG :::.:.: :::...:::::.:..: ..... :.. ... . :.. . :. . :.. NP_631 MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWI--GILTLYLMHRGKLDCAGGALLSSY 10 20 30 40 50 60 70 80 90 100 110 pF1KSD RGYLGILLSCMIAEM-AIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVW : :::. .: . ::. .:::: : :: ::. .::.:::.. :...: .: .: NP_631 LIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLR-ATKRRQRNL ... ..: : :. : .. :: .:..: .. .... :::: : .. : . . NP_631 VADG-VQC-DRTVVNGIIATVVVSWIIIAATVVSIIIVFDPLGGKMAPYSSAGPSHLDSH 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD RTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDII . .: . :. . .. : :.:.. :: : :.: : ::. .: : :.::::: NP_631 DSSQLLNGLKTAATSVWETRIKLLCCCIGKDDHTRVAFSSTAELFSTYFSDTDLVPSDIA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD AGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCY-YM :::.::.:.: :: :.. . : . . :: :. : :. :: NP_631 AGLALLHQQQDNIRN------NQEPAQVVCHAPGSSQEADLD----AEL----ENCHHYM 240 250 260 270 280 300 310 320 330 340 350 pF1KSD LFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRR :: ::::::.:..:.: :::... .: : .: : .. :: . . NP_631 QFAAAAYGWPLYIYRNPLTGLCRIGGDC----CRSRTTDYDLVGGDQLNCHFGSIL---- 290 300 310 320 330 360 370 380 390 400 410 pF1KSD HFLDENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAER : .. :....: :: ::: :: ::.:: :..::...:::.: .:.::::....: NP_631 H--TTGLQYRDFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSAESEV 340 350 360 370 380 390 420 430 440 450 460 470 pF1KSD LPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAG : :: . :.:::. .:.:. ..: .. .:::::. . .: :..::::::.: NP_631 LDVECEVQDRLAHKGISQAARYVYQRLINDGILSQAFSI-----APEYRLVIVGHSLGGG 400 410 420 430 440 480 490 500 510 520 530 pF1KSD TAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEG .::.:. .:: :: ..:.:.::: :: :. .:::. :....:::::..::.....:: NP_631 AAALLATMLRAAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVTNLED 450 460 470 480 490 500 540 550 560 570 pF1KSD FRRQLLDVLQRSTKPKWRIIV---------GATKCIPKSELP---EEVEVTTLAS----- ..:..: :. . .:::..:.. : . .: .:: .:: . : . NP_631 LKRRILRVVAHCNKPKYKILLHGLWYELFGGNPNNLP-TELDGGDQEVLTQPLLGEQSLL 510 520 530 540 550 560 580 590 600 610 620 630 pF1KSD TRLWT----HPSDLTIALSAS-TPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDN :: :. :: . : . ::::::::::. .. . . :: . : : :. . NP_631 TR-WSPAYSFSSDSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAH--YSAKWSHE 570 580 590 600 610 620 640 650 660 670 680 690 pF1KSD KAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIF :....:.: :: .:.: ..:..:..:. . ..: .: :: ..: NP_631 AEFSKILIGPKMLTDHMPDILMRALDSVVSD----RAACVSCPAQGVSSVDVA 630 640 650 660 670 700 710 720 730 740 750 pF1KSD QQQPLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDP 1042 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:33:47 2016 done: Thu Nov 3 02:33:49 2016 Total Scan time: 12.560 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]