FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0661, 1001 aa 1>>>pF1KSDA0661 1001 - 1001 aa - 1001 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7301+/-0.00114; mu= -0.8112+/- 0.068 mean_var=364.6149+/-76.677, 0's: 0 Z-trim(113.1): 76 B-trim: 328 in 2/52 Lambda= 0.067167 statistics sampled from 13742 (13811) to 13742 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.424), width: 16 Scan time: 5.780 The best scores are: opt bits E(32554) CCDS10691.1 RNF40 gene_id:9810|Hs108|chr16 (1001) 6414 636.4 8.5e-182 CCDS55994.1 RNF40 gene_id:9810|Hs108|chr16 ( 901) 3710 374.4 5.9e-103 CCDS35084.1 RNF20 gene_id:56254|Hs108|chr9 ( 975) 1804 189.7 2.5e-47 >>CCDS10691.1 RNF40 gene_id:9810|Hs108|chr16 (1001 aa) initn: 6414 init1: 6414 opt: 6414 Z-score: 3377.3 bits: 636.4 E(32554): 8.5e-182 Smith-Waterman score: 6414; 100.0% identity (100.0% similar) in 1001 aa overlap (1-1001:1-1001) 10 20 30 40 50 60 pF1KSD MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD APEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 APEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPIN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD REMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 REMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 IADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD ESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVL 910 920 930 940 950 960 970 980 990 1000 pF1KSD TKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS ::::::::::::::::::::::::::::::::::::::::: CCDS10 TKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS 970 980 990 1000 >>CCDS55994.1 RNF40 gene_id:9810|Hs108|chr16 (901 aa) initn: 3674 init1: 3674 opt: 3710 Z-score: 1961.8 bits: 374.4 E(32554): 5.9e-103 Smith-Waterman score: 5589; 90.0% identity (90.0% similar) in 1001 aa overlap (1-1001:1-901) 10 20 30 40 50 60 pF1KSD MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD APEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 APEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAEL ::::::::::::::::::::::::::::::: CCDS55 AEALEQLNSGYYVSGSSSGFQGGQITLSMQK----------------------------- 310 320 330 370 380 390 400 410 420 pF1KSD QGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATK CCDS55 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KSD NSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPIN ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 -----------SDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPIN 340 350 360 370 380 490 500 510 520 530 540 pF1KSD REMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 REMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGV 390 400 410 420 430 440 550 560 570 580 590 600 pF1KSD SAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPS 450 460 470 480 490 500 610 620 630 640 650 660 pF1KSD SRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELK 510 520 530 540 550 560 670 680 690 700 710 720 pF1KSD KAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKK 570 580 590 600 610 620 730 740 750 760 770 780 pF1KSD IADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLR 630 640 650 660 670 680 790 800 810 820 830 840 pF1KSD EKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQG 690 700 710 720 730 740 850 860 870 880 890 900 pF1KSD SLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREK 750 760 770 780 790 800 910 920 930 940 950 960 pF1KSD ESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVL 810 820 830 840 850 860 970 980 990 1000 pF1KSD TKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS ::::::::::::::::::::::::::::::::::::::::: CCDS55 TKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS 870 880 890 900 >>CCDS35084.1 RNF20 gene_id:56254|Hs108|chr9 (975 aa) initn: 3082 init1: 1767 opt: 1804 Z-score: 963.2 bits: 189.7 E(32554): 2.5e-47 Smith-Waterman score: 3581; 58.8% identity (81.3% similar) in 1005 aa overlap (1-1000:1-974) 10 20 30 40 50 pF1KSD MSGPGNKRAAGDGGSG-PPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKL ::: :::::::. :.. ::::: . :.. :: .: :.:::.:::::.:...:: ::.:: CCDS35 MSGIGNKRAAGEPGTSMPPEKKAAVEDSGTT--VETIKLGGVSSTEELDIRTLQTKNRKL 10 20 30 40 50 60 70 80 90 100 110 pF1KSD AERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHE-SQGEL :: :.:::: ::::::.:::::.:::::::.::::::::.:.::... .:. .. :: CCDS35 AEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLEQGLG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVE . : . .: ::: .. .. . : .:::..:...:..:::::.: CCDS35 DLLTERKALV-------VPEPEPDSDSNQERKDDRERGEGQEPAFSFLATLASSSSEEME 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD LELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENR .:: :.: :. :::..: . :.::..:: : ... : ::. . ::.: . :..:: CCDS35 SQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNS-GDNLIVEEAVQELNSFLAQENM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD RLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNK :::.:. :::::. .: :.:.::.:: .::..: .:. ..::::::.:.:::::.::. CCDS35 RLQELTDLLQEKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD HLAEALEQLNS-GYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQ ::::.::..:: :: : :..:.. :: ::.. .::: .:::::::.:::..:. :::::. CCDS35 HLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELAQNRLCELEKLR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KSD AELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLL ... .. ::.::: ::: :.::.:: ::: .:.:::.:::::::.:..::::: :: CCDS35 QDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLH 360 370 380 390 400 410 420 430 440 450 460 470 pF1KSD ATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAG .:...: ...: .: ::..:.::::::::::::::::::::::::::::::.:::::::: CCDS35 GTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAG 420 430 440 450 460 470 480 490 500 510 520 530 pF1KSD PINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSA--HSTPNLGHP ::::::::::::::::::::::.. ::::::::.:....: : . :::: .: . : CCDS35 PINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLR-SGSALLQSQSSTEDP 480 490 500 510 520 540 550 560 570 580 590 pF1KSD EDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPG .: :: : ::. .... .... .: . . . :..: . CCDS35 KDE----PAELK----------PDS-EDLS--SQSSASKASQEDANEIKSKRDEEE-RER 530 540 550 560 570 600 610 620 630 640 650 pF1KSD AQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGL . . : :: : : :.. :::: .: : :.::.: .. ..::.:..: : CCDS35 ERREKERERERE-REKEKEREREKQKLKESEKERD-SAKDKEKGKHDDGRKKEAEIIKQL 580 590 600 610 620 660 670 680 690 700 710 pF1KSD RAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDR . :::::::::::::::::::.::::::::::::::::.:.:::...::.:...::.... CCDS35 KIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEK 630 640 650 660 670 680 720 730 740 750 760 770 pF1KSD RESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRL .:.::.:::::::.:: .:::::.::.::. .::::::::::::::::::::::::: :: CCDS35 KENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRL 690 700 710 720 730 740 780 790 800 810 820 830 pF1KSD LQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKE .:::::::::::::::::::.:::::::.:::.::..::: ::.:::::: .:.:::::: CCDS35 MQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKE 750 760 770 780 790 800 840 850 860 870 880 890 pF1KSD RALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESR . ::...: :::: ::.::::.:::::.::::::.:::.::: .: .:...: ..:. CCDS35 HLLQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENS 810 820 830 840 850 860 900 910 920 930 940 950 pF1KSD AAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRK ...::. ::.::::::::::::::: .: . ::::.::::.::::::::::: :: CCDS35 VTKEKDMFNFKRAQEDISRLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPCCNMRK 870 880 890 900 910 920 960 970 980 990 1000 pF1KSD KDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS :::::::::::::::::. ::..::::::::::::::.::::::: CCDS35 KDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG 930 940 950 960 970 1001 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:37:29 2016 done: Thu Nov 3 18:37:30 2016 Total Scan time: 5.780 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]