FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0668, 717 aa 1>>>pF1KSDA0668 717 - 717 aa - 717 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5603+/-0.000422; mu= 10.0612+/- 0.026 mean_var=168.9450+/-34.201, 0's: 0 Z-trim(116.7): 51 B-trim: 464 in 2/56 Lambda= 0.098674 statistics sampled from 27942 (27993) to 27942 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.328), width: 16 Scan time: 12.500 The best scores are: opt bits E(85289) NP_001186509 (OMIM: 613569) SUN domain-containing ( 717) 4733 686.7 8.6e-197 NP_056189 (OMIM: 613569) SUN domain-containing pro ( 717) 4733 686.7 8.6e-197 XP_016884237 (OMIM: 613569) PREDICTED: SUN domain- ( 683) 4467 648.8 2.1e-185 NP_001186508 (OMIM: 613569) SUN domain-containing ( 738) 3813 555.7 2.3e-157 XP_011528406 (OMIM: 613569) PREDICTED: SUN domain- ( 671) 3811 555.4 2.6e-157 XP_011528407 (OMIM: 613569) PREDICTED: SUN domain- ( 706) 3811 555.4 2.7e-157 NP_001165415 (OMIM: 607723) SUN domain-containing ( 682) 1036 160.4 2.2e-38 NP_079430 (OMIM: 607723) SUN domain-containing pro ( 702) 1036 160.4 2.3e-38 NP_001124437 (OMIM: 607723) SUN domain-containing ( 785) 1036 160.4 2.5e-38 XP_005260577 (OMIM: 603038) PREDICTED: sperm-assoc ( 344) 543 89.9 1.8e-17 NP_001304860 (OMIM: 603038) sperm-associated antig ( 360) 543 89.9 1.8e-17 XP_011527311 (OMIM: 603038) PREDICTED: sperm-assoc ( 393) 543 90.0 2e-17 NP_003107 (OMIM: 603038) sperm-associated antigen ( 437) 543 90.0 2.1e-17 XP_011526877 (OMIM: 613942) PREDICTED: SUN domain- ( 289) 490 82.3 2.9e-15 XP_011526876 (OMIM: 613942) PREDICTED: SUN domain- ( 354) 490 82.4 3.4e-15 NP_542406 (OMIM: 613942) SUN domain-containing pro ( 379) 490 82.4 3.6e-15 XP_011526875 (OMIM: 613942) PREDICTED: SUN domain- ( 402) 490 82.4 3.7e-15 >>NP_001186509 (OMIM: 613569) SUN domain-containing prot (717 aa) initn: 4733 init1: 4733 opt: 4733 Z-score: 3654.1 bits: 686.7 E(85289): 8.6e-197 Smith-Waterman score: 4733; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 610 620 630 640 650 660 670 680 690 700 710 pF1KSD LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 670 680 690 700 710 >>NP_056189 (OMIM: 613569) SUN domain-containing protein (717 aa) initn: 4733 init1: 4733 opt: 4733 Z-score: 3654.1 bits: 686.7 E(85289): 8.6e-197 Smith-Waterman score: 4733; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 610 620 630 640 650 660 670 680 690 700 710 pF1KSD LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 670 680 690 700 710 >>XP_016884237 (OMIM: 613569) PREDICTED: SUN domain-cont (683 aa) initn: 4467 init1: 4467 opt: 4467 Z-score: 3449.7 bits: 648.8 E(85289): 2.1e-185 Smith-Waterman score: 4467; 100.0% identity (100.0% similar) in 680 aa overlap (1-680:1-680) 10 20 30 40 50 60 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 610 620 630 640 650 660 670 680 690 700 710 pF1KSD LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH :::::::::::::::::::: XP_016 LLGKFTYDQDGEPIQTFHFQLKM 670 680 >>NP_001186508 (OMIM: 613569) SUN domain-containing prot (738 aa) initn: 3805 init1: 3805 opt: 3813 Z-score: 2946.1 bits: 555.7 E(85289): 2.3e-157 Smith-Waterman score: 4681; 97.2% identity (97.2% similar) in 738 aa overlap (1-717:1-738) 10 20 30 40 50 60 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG 70 80 90 100 110 120 130 140 150 pF1KSD RKATEDFLGSSSGYSSEDDYV---------------------GYSDVDQQSSSSRLRSAV ::::::::::::::::::::: :::::::::::::::::: NP_001 RKATEDFLGSSSGYSSEDDYVEDSEGRGSKVTETEPVSSFPAGYSDVDQQSSSSRLRSAV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD SRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD LLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD VHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRR 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD EAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD QESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPA 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD WISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD VIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGI 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD PLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD SSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWG 670 680 690 700 710 720 700 710 pF1KSD HPEYTCIYRFRVHGEPAH :::::::::::::::::: NP_001 HPEYTCIYRFRVHGEPAH 730 >>XP_011528406 (OMIM: 613569) PREDICTED: SUN domain-cont (671 aa) initn: 3806 init1: 3806 opt: 3811 Z-score: 2945.1 bits: 555.4 E(85289): 2.6e-157 Smith-Waterman score: 4337; 93.6% identity (93.6% similar) in 717 aa overlap (1-717:1-671) 10 20 30 40 50 60 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG :::::::::::::::::::::::::::::::::::: XP_011 PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWG------------------------ 70 80 90 130 140 150 160 170 180 pF1KSD RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL :::::::::::::::::::::::::::::::::::::: XP_011 ----------------------YSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL 100 110 120 130 190 200 210 220 230 240 pF1KSD YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT 140 150 160 170 180 190 250 260 270 280 290 300 pF1KSD FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK 200 210 220 230 240 250 310 320 330 340 350 360 pF1KSD EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS 260 270 280 290 300 310 370 380 390 400 410 420 pF1KSD ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG 320 330 340 350 360 370 430 440 450 460 470 480 pF1KSD LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE 380 390 400 410 420 430 490 500 510 520 530 540 pF1KSD MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS 440 450 460 470 480 490 550 560 570 580 590 600 pF1KSD EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN 500 510 520 530 540 550 610 620 630 640 650 660 pF1KSD CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT 560 570 580 590 600 610 670 680 690 700 710 pF1KSD LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH 620 630 640 650 660 670 >>XP_011528407 (OMIM: 613569) PREDICTED: SUN domain-cont (706 aa) initn: 3806 init1: 3806 opt: 3811 Z-score: 2944.8 bits: 555.4 E(85289): 2.7e-157 Smith-Waterman score: 4337; 93.6% identity (93.6% similar) in 717 aa overlap (1-717:36-706) 10 20 30 pF1KSD MSRRSQRLTRYSQGDDDGSSSSGGSSVAGS :::::::::::::::::::::::::::::: XP_011 SAGQRLRGVPVWAAGAFRFSSGEESTSHLIMSRRSQRLTRYSQGDDDGSSSSGGSSVAGS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD QSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESLVHESWFPPRSSLEELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESLVHESWFPPRSSLEELH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD GDANWGEDLRVRRRRGTGGSESSRASGLVGRKATEDFLGSSSGYSSEDDYVGYSDVDQQS :::::: :::::::: XP_011 GDANWG----------------------------------------------YSDVDQQS 130 160 170 180 190 200 210 pF1KSD SSSRLRSAVSRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSRLRSAVSRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL 140 150 160 170 180 190 220 230 240 250 260 270 pF1KSD KTFLWFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTFLWFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHF 200 210 220 230 240 250 280 290 300 310 320 330 pF1KSD QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLA 260 270 280 290 300 310 340 350 360 370 380 390 pF1KSD LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQ 320 330 340 350 360 370 400 410 420 430 440 450 pF1KSD LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVR 380 390 400 410 420 430 460 470 480 490 500 510 pF1KSD DDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAAS 440 450 460 470 480 490 520 530 540 550 560 570 pF1KSD LSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETK 500 510 520 530 540 550 580 590 600 610 620 630 pF1KSD TALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVP 560 570 580 590 600 610 640 650 660 670 680 690 pF1KSD KALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVV 620 630 640 650 660 670 700 710 pF1KSD ELRILTNWGHPEYTCIYRFRVHGEPAH ::::::::::::::::::::::::::: XP_011 ELRILTNWGHPEYTCIYRFRVHGEPAH 680 690 700 >>NP_001165415 (OMIM: 607723) SUN domain-containing prot (682 aa) initn: 1113 init1: 757 opt: 1036 Z-score: 810.0 bits: 160.4 E(85289): 2.2e-38 Smith-Waterman score: 1185; 35.4% identity (62.0% similar) in 718 aa overlap (48-715:4-680) 20 30 40 50 60 70 pF1KSD GSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHT-----SYYSE : .. :: :: : . ..: :: :. NP_001 MDFSRLHMYSP-PQCVPENTGYTYALSSSYSSD 10 20 30 80 90 100 110 120 pF1KSD SLVHESWF---P----PRSSLEELH---GDANWGEDLRVRRRRGTGGSESSRASGLVGRK .: :. : :: : . :. . :. : ::... : . . : NP_001 ALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTK 40 50 60 70 80 90 130 140 150 160 170 pF1KSD ATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLL---WMVATSP-----G .. :. . . . : : :.. .. : :..::.: .: :. . : NP_001 QRRSTNKSAFSINHVSRQVTSSGVSHGGTVS-LQDAVTRRPPVLDESWIREQTTVDHFWG 100 110 120 130 140 150 180 190 200 210 220 230 pF1KSD RLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTY-GAWYF . ..:: : ::...: : :.::.::: . .. :: .:.::.:: :. : : NP_001 KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLGLSLRGQGNF 160 170 180 190 200 210 240 250 260 270 280 pF1KSD YPYGLQTFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAEQRV-----MSRVHS . .: :.: .: . . ..: :. . .: ..: .:..... :: :.. NP_001 F-----SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGDSEAFPWHWMSGVEQ 220 230 240 250 260 290 300 310 320 330 340 pF1KSD LERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAA : . . . : .. . :..:. : .::..: : .: :.:. NP_001 QVASLSGQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS-----------ASVRDAV 270 280 290 300 310 350 360 370 380 390 400 pF1KSD LKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQES . . . : ::. .: : ::.. :. . :. . ...: :.. : . :. NP_001 GQPPRETDFMAFHQEH--EVRMSHL---EDILGKLREKSEAIQKELEQTKQKTISAVGEQ 320 330 340 350 360 410 420 430 440 450 460 pF1KSD FQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWIS . . :..:. ::: ..::.. ... . ..::.. :. : .. NP_001 LLPT-VEHLQLELDQL---KSELSSWRHVKTGC--------ETVDAVQERVDVQVREMVK 370 380 390 400 410 470 480 490 500 pF1KSD QFLARG--GGGRVGLLQRE--------EMQAQLRELESKILT----HVAEMQGKSAREAA .... ::. :::: ..:..::.:. .:: ::. . . ::. NP_001 LLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAV 420 430 440 450 460 470 510 520 530 540 550 560 pF1KSD ASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYE .: .... :. :.:: :.. ::..::. ::.:. :..:.::::::.:..::::::::: NP_001 VS---AVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYE 480 490 500 510 520 530 570 580 590 600 610 620 pF1KSD TKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEH :::::.::::::::: ::::::..:::..:::::::.: ::. ::::: :.:.: :::: NP_001 TKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEH 540 550 560 570 580 590 630 640 650 660 670 680 pF1KSD VPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFH-FQAPTMATY .::.:::...:::::::::..:.... :.:: :::.:::::::: .: :. .. : ... NP_001 IPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAF 600 610 620 630 640 650 690 700 710 pF1KSD QVVELRILTNWGHPEYTCIYRFRVHGEPAH :.:::::..:::::::::.::::::::: NP_001 QIVELRIFSNWGHPEYTCLYRFRVHGEPVK 660 670 680 >>NP_079430 (OMIM: 607723) SUN domain-containing protein (702 aa) initn: 1110 init1: 757 opt: 1036 Z-score: 809.9 bits: 160.4 E(85289): 2.3e-38 Smith-Waterman score: 1231; 35.5% identity (62.7% similar) in 761 aa overlap (1-715:1-700) 10 20 30 40 50 pF1KSD MSRRSQRL--TRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLK-RKSSNMKRLSP-- ::::: :: : . :: .. ....:.: : : .:. :: : :.:.: . .: NP_079 MSRRSLRLATTACTLGDGEAVGADSGTSSAVS----LKNRAARTTKQRRSTNKSAFSINH 10 20 30 40 50 60 70 80 90 100 pF1KSD -APQLGPSSDAHTSYYS--------ESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRG . :. :. .: . : .. :::. ....... : . : ::. NP_079 VSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDG-DLK------ 60 70 80 90 100 110 120 130 140 150 160 pF1KSD TGGSESS-RASGLVGRKAT---EDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRA ::.... ...: :: :. . : :. .. :: : . . ::. :: NP_079 -GGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVY---SRD 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD GSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPL-L . : .:.. ..:: : ::...: : :.::.::: . .. :: .:.:: : NP_079 RNQKWKAASG-------VFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFL 170 180 190 200 210 230 240 250 260 270 pF1KSD LLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAEQ ::. :. : :. .: :.: .: . . ..: :. . .: ..: .:... NP_079 LLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGDS 220 230 240 250 260 270 280 290 300 310 320 pF1KSD RV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTL .. :: :.. : . . . : .. . :..:. : .::..: : NP_079 EAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS----- 280 290 300 310 320 330 340 350 360 370 380 pF1KSD ALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQ .: :.:. . . . : ::. .: : ::.. :. . :. . ... NP_079 ------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKLREKSEAIQKELE 330 340 350 360 370 390 400 410 420 430 440 pF1KSD QLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAV : :.. : . :.. . :..:. :: :..::.. ... . ..:: NP_079 QTKQKTISAVGEQLLPT-VEHLQLELDQ---LKSELSSWRHVKTGC--------ETVDAV 380 390 400 410 420 450 460 470 480 490 pF1KSD RDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRELESKILT----H .. :. : .. .... ::. :::: ..:..::.:. .:: : NP_079 QERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHH 430 440 450 460 470 480 500 510 520 530 540 550 pF1KSD VAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGG :. . . ::..: .... :. :.:: :.. ::..::. ::.:. :..:.:::::: NP_079 VSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGG 490 500 510 520 530 560 570 580 590 600 610 pF1KSD ASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRL .:..::::::::::::::.::::::::: ::::::..:::..:::::::.: ::. :::: NP_079 GSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRL 540 550 560 570 580 590 620 630 640 650 660 670 pF1KSD SARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQ : :.:.: ::::.::.:::...:::::::::..:.... :.:: :::.:::::::: .: NP_079 SMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQ 600 610 620 630 640 650 680 690 700 710 pF1KSD TFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH :. .. : ...:.:::::..:::::::::.::::::::: NP_079 MFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK 660 670 680 690 700 >>NP_001124437 (OMIM: 607723) SUN domain-containing prot (785 aa) initn: 1150 init1: 757 opt: 1036 Z-score: 809.2 bits: 160.4 E(85289): 2.5e-38 Smith-Waterman score: 1256; 34.9% identity (62.5% similar) in 776 aa overlap (1-715:51-783) 10 20 pF1KSD MSRRSQRL--TRYSQGDDDGSSSSGGSSVA ::::: :: : . :: .. ....:.: : NP_001 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA 30 40 50 60 70 80 30 40 50 60 70 pF1KSD GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH : .:. :: : :.:.: . .: . :. :. .: . : .. NP_001 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLD 90 100 110 120 130 80 90 100 110 120 pF1KSD ESWFPPRSSLEEL-----HGDANWGEDLRVRRRRGTGGSESSRASGLVGRKAT-----ED :::. ....... :: . :. .. .:.. .. .:. . . .: NP_001 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKD 140 150 160 170 180 190 130 140 150 160 170 pF1KSD FLGSSSGYSSEDDYVGYSDVDQQSSS--SRLR------SAVSR-AGSLLWMVATSPGRLF : . . . . : : .:. . :: .:::: : : ::.....::. NP_001 VLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAA 200 210 220 230 240 250 180 190 200 210 220 230 pF1KSD RLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPL-LLLTCLTY-GAWYFYP ..:: : ::...: : :.::.::: . .. :: .:.:: :::. :. : :. NP_001 SGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFF- 260 270 280 290 300 310 240 250 260 270 280 pF1KSD YGLQTFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAEQRV-----MSRVHSLE .: :.: .: . . ..: :. . .: ..: .:..... :: :.. NP_001 ----SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGDSEAFPWHWMSGVEQQV 320 330 340 350 360 290 300 310 320 330 340 pF1KSD RRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALK : . . . : .. . :..:. : .::..: : .: :.:. . NP_001 ASLSGQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS-----------ASVRDAVGQ 370 380 390 400 410 350 360 370 380 390 400 pF1KSD EDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQ . . : ::. .: : ::.. :. . :. . ...: :.. : . :.. NP_001 PPRETDFMAFHQEH--EVRMSHL---EDILGKLREKSEAIQKELEQTKQKTISAVGEQLL 420 430 440 450 460 470 410 420 430 440 450 460 pF1KSD ESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQF . :..:. :: :..::.. ... . ..::.. :. : .. . NP_001 PT-VEHLQLELDQ---LKSELSSWRHVKTGC--------ETVDAVQERVDVQVREMVKLL 480 490 500 510 520 470 480 490 500 510 pF1KSD LARG--GGGRVGLLQRE--------EMQAQLRELESKILT----HVAEMQGKSAREAAAS ... ::. :::: ..:..::.:. .:: ::. . . ::..: NP_001 FSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVS 530 540 550 560 570 580 520 530 540 550 560 570 pF1KSD LSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETK .... :. :.:: :.. ::..::. ::.:. :..:.::::::.:..::::::::::: NP_001 ---AVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETK 590 600 610 620 630 580 590 600 610 620 630 pF1KSD TALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVP :::.::::::::: ::::::..:::..:::::::.: ::. ::::: :.:.: ::::.: NP_001 TALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIP 640 650 660 670 680 690 640 650 660 670 680 pF1KSD KALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFH-FQAPTMATYQV :.:::...:::::::::..:.... :.:: :::.:::::::: .: :. .. : ...:. NP_001 KTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQI 700 710 720 730 740 750 690 700 710 pF1KSD VELRILTNWGHPEYTCIYRFRVHGEPAH :::::..:::::::::.::::::::: NP_001 VELRIFSNWGHPEYTCLYRFRVHGEPVK 760 770 780 >>XP_005260577 (OMIM: 603038) PREDICTED: sperm-associate (344 aa) initn: 520 init1: 319 opt: 543 Z-score: 434.7 bits: 89.9 E(85289): 1.8e-17 Smith-Waterman score: 543; 39.7% identity (68.2% similar) in 214 aa overlap (500-713:119-329) 470 480 490 500 510 520 pF1KSD GGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVH ::.. .. : :. :.:: : : . . XP_005 WLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELD-KLHKE-VSTVRAANSE 90 100 110 120 130 140 530 540 550 560 570 580 pF1KSD HIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPR ...: ..:: .:: . :::: : :::. . :. : ... . .: ... : XP_005 RVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPT 150 160 170 180 190 200 590 600 610 620 630 640 pF1KSD VILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIF :::.: : :::::::.: :: .:..: .:.. . .::.: : .. .. .:::.:::.: XP_005 VILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVF 210 220 230 240 250 260 650 660 670 680 690 700 pF1KSD GFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRF :.. . : .: ::::.: . :::::.: :.. :...::.:::::..::.:: XP_005 GLQVYDETEVSL-GKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRV 270 280 290 300 310 320 710 pF1KSD RVHGEPAH :.:: XP_005 RAHGVRTSEGAEGSAQGPH 330 340 717 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:37:54 2016 done: Thu Nov 3 02:37:55 2016 Total Scan time: 12.500 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]