Result of FASTA (omim) for
pF1KSDA0704
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0704, 887 aa
1>>>pF1KSDA0704 887 - 887 aa - 887 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1307+/-0.000405; mu= 11.7071+/- 0.025
mean_var=105.6590+/-22.906, 0's: 0 Z-trim(114.0): 163 B-trim: 674 in 1/51
Lambda= 0.124773
statistics sampled from 23492 (23661) to 23492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.277), width: 16
Scan time: 13.860
The best scores are: opt bits E(85289)
XP_005249755 (OMIM: 606732) PREDICTED: oxysterol-b ( 887) 5974 1086.8 0
XP_011513560 (OMIM: 606732) PREDICTED: oxysterol-b ( 887) 5974 1086.8 0
NP_056365 (OMIM: 606732) oxysterol-binding protein ( 887) 5974 1086.8 0
XP_016867437 (OMIM: 606732) PREDICTED: oxysterol-b ( 843) 5688 1035.3 0
XP_011513561 (OMIM: 606732) PREDICTED: oxysterol-b ( 843) 5688 1035.3 0
XP_006715744 (OMIM: 606732) PREDICTED: oxysterol-b ( 856) 4037 738.1 4.1e-212
NP_663160 (OMIM: 606732) oxysterol-binding protein ( 856) 4037 738.1 4.1e-212
XP_006715747 (OMIM: 606732) PREDICTED: oxysterol-b ( 534) 3600 659.4 1.3e-188
NP_115912 (OMIM: 606734) oxysterol-binding protein ( 934) 3532 647.2 1e-184
XP_016858761 (OMIM: 606734) PREDICTED: oxysterol-b ( 892) 3236 594.0 1.1e-168
XP_016867438 (OMIM: 606732) PREDICTED: oxysterol-b ( 807) 3207 588.7 3.6e-167
XP_006715746 (OMIM: 606732) PREDICTED: oxysterol-b ( 820) 3207 588.7 3.7e-167
NP_663162 (OMIM: 606732) oxysterol-binding protein ( 820) 3207 588.7 3.7e-167
NP_663161 (OMIM: 606732) oxysterol-binding protein ( 851) 3207 588.7 3.8e-167
XP_006715745 (OMIM: 606732) PREDICTED: oxysterol-b ( 851) 3207 588.7 3.8e-167
XP_016858758 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 3172 582.4 3.2e-165
XP_016858757 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 3172 582.4 3.2e-165
XP_011508841 (OMIM: 606734) PREDICTED: oxysterol-b ( 928) 2614 482.0 5.6e-135
NP_665682 (OMIM: 606734) oxysterol-binding protein ( 938) 2614 482.0 5.7e-135
XP_016858755 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 2614 482.0 5.8e-135
NP_001188409 (OMIM: 606734) oxysterol-binding prot ( 959) 2614 482.0 5.8e-135
XP_016858756 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 2614 482.0 5.8e-135
XP_016858754 (OMIM: 606734) PREDICTED: oxysterol-b ( 981) 2614 482.0 5.9e-135
XP_016858762 (OMIM: 606734) PREDICTED: oxysterol-b ( 872) 2610 481.3 8.8e-135
XP_016858759 (OMIM: 606734) PREDICTED: oxysterol-b ( 903) 2610 481.3 9e-135
NP_001188410 (OMIM: 606734) oxysterol-binding prot ( 903) 2610 481.3 9e-135
XP_016858766 (OMIM: 606734) PREDICTED: oxysterol-b ( 836) 2279 421.7 7.3e-117
XP_016858763 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 2279 421.7 7.5e-117
XP_016858765 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 2279 421.7 7.5e-117
XP_016858764 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 2279 421.7 7.5e-117
XP_016858760 (OMIM: 606734) PREDICTED: oxysterol-b ( 898) 2279 421.7 7.8e-117
NP_001188411 (OMIM: 606734) oxysterol-binding prot ( 898) 2279 421.7 7.8e-117
NP_665741 (OMIM: 606735) oxysterol-binding protein ( 842) 2087 387.1 1.9e-106
XP_016879613 (OMIM: 606735) PREDICTED: oxysterol-b ( 870) 1996 370.7 1.6e-101
XP_016879611 (OMIM: 606735) PREDICTED: oxysterol-b ( 888) 1996 370.7 1.7e-101
XP_016879612 (OMIM: 606735) PREDICTED: oxysterol-b ( 888) 1996 370.7 1.7e-101
XP_016879614 (OMIM: 606735) PREDICTED: oxysterol-b ( 450) 1823 339.5 2.2e-92
NP_001229437 (OMIM: 606730) oxysterol-binding prot ( 568) 829 160.6 1.9e-38
XP_006722443 (OMIM: 606730) PREDICTED: oxysterol-b ( 925) 829 160.7 3e-38
NP_542164 (OMIM: 606730) oxysterol-binding protein ( 950) 829 160.7 3.1e-38
XP_016881019 (OMIM: 606730) PREDICTED: oxysterol-b ( 968) 829 160.7 3.1e-38
XP_016883657 (OMIM: 606731,616340) PREDICTED: oxys ( 370) 811 157.3 1.2e-37
NP_653081 (OMIM: 606731,616340) oxysterol-binding ( 480) 811 157.3 1.6e-37
XP_016883654 (OMIM: 606731,616340) PREDICTED: oxys ( 480) 811 157.3 1.6e-37
XP_016883653 (OMIM: 606731,616340) PREDICTED: oxys ( 516) 811 157.3 1.7e-37
XP_016883652 (OMIM: 606731,616340) PREDICTED: oxys ( 516) 811 157.3 1.7e-37
NP_060500 (OMIM: 606730) oxysterol-binding protein ( 437) 809 157.0 1.9e-37
XP_016881023 (OMIM: 606730) PREDICTED: oxysterol-b ( 437) 809 157.0 1.9e-37
XP_016881022 (OMIM: 606730) PREDICTED: oxysterol-b ( 437) 809 157.0 1.9e-37
NP_002547 (OMIM: 167040) oxysterol-binding protein ( 807) 791 153.8 3e-36
>>XP_005249755 (OMIM: 606732) PREDICTED: oxysterol-bindi (887 aa)
initn: 5974 init1: 5974 opt: 5974 Z-score: 5813.3 bits: 1086.8 E(85289): 0
Smith-Waterman score: 5974; 100.0% identity (100.0% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KSD MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
790 800 810 820 830 840
850 860 870 880
pF1KSD RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
850 860 870 880
>>XP_011513560 (OMIM: 606732) PREDICTED: oxysterol-bindi (887 aa)
initn: 5974 init1: 5974 opt: 5974 Z-score: 5813.3 bits: 1086.8 E(85289): 0
Smith-Waterman score: 5974; 100.0% identity (100.0% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KSD MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
790 800 810 820 830 840
850 860 870 880
pF1KSD RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
850 860 870 880
>>NP_056365 (OMIM: 606732) oxysterol-binding protein-rel (887 aa)
initn: 5974 init1: 5974 opt: 5974 Z-score: 5813.3 bits: 1086.8 E(85289): 0
Smith-Waterman score: 5974; 100.0% identity (100.0% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KSD MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
790 800 810 820 830 840
850 860 870 880
pF1KSD RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
850 860 870 880
>>XP_016867437 (OMIM: 606732) PREDICTED: oxysterol-bindi (843 aa)
initn: 5688 init1: 5688 opt: 5688 Z-score: 5535.5 bits: 1035.3 E(85289): 0
Smith-Waterman score: 5688; 100.0% identity (100.0% similar) in 843 aa overlap (45-887:1-843)
20 30 40 50 60 70
pF1KSD VSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFF
::::::::::::::::::::::::::::::
XP_016 MNYTQEPPVQKGFLLKKRKWPLKGWHKRFF
10 20 30
80 90 100 110 120 130
pF1KSD YLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD DEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD TGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD INAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFG
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD EEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD AQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVH
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF
760 770 780 790 800 810
860 870 880
pF1KSD FRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::
XP_016 FRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
820 830 840
>>XP_011513561 (OMIM: 606732) PREDICTED: oxysterol-bindi (843 aa)
initn: 5688 init1: 5688 opt: 5688 Z-score: 5535.5 bits: 1035.3 E(85289): 0
Smith-Waterman score: 5688; 100.0% identity (100.0% similar) in 843 aa overlap (45-887:1-843)
20 30 40 50 60 70
pF1KSD VSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFF
::::::::::::::::::::::::::::::
XP_011 MNYTQEPPVQKGFLLKKRKWPLKGWHKRFF
10 20 30
80 90 100 110 120 130
pF1KSD YLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVF
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD DEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD TGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD INAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFG
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD EEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD AQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVH
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF
760 770 780 790 800 810
860 870 880
pF1KSD FRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::
XP_011 FRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
820 830 840
>>XP_006715744 (OMIM: 606732) PREDICTED: oxysterol-bindi (856 aa)
initn: 4037 init1: 4037 opt: 4037 Z-score: 3929.2 bits: 738.1 E(85289): 4.1e-212
Smith-Waterman score: 5690; 96.5% identity (96.5% similar) in 887 aa overlap (1-887:1-856)
10 20 30 40 50 60
pF1KSD MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
::::::::::::::::::: ::::::::::
XP_006 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR
250 260
310 320 330 340 350 360
pF1KSD LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
630 640 650 660 670 680
730 740 750 760 770 780
pF1KSD NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
690 700 710 720 730 740
790 800 810 820 830 840
pF1KSD QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
750 760 770 780 790 800
850 860 870 880
pF1KSD RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
810 820 830 840 850
>>NP_663160 (OMIM: 606732) oxysterol-binding protein-rel (856 aa)
initn: 4037 init1: 4037 opt: 4037 Z-score: 3929.2 bits: 738.1 E(85289): 4.1e-212
Smith-Waterman score: 5690; 96.5% identity (96.5% similar) in 887 aa overlap (1-887:1-856)
10 20 30 40 50 60
pF1KSD MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
::::::::::::::::::: ::::::::::
NP_663 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR
250 260
310 320 330 340 350 360
pF1KSD LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
630 640 650 660 670 680
730 740 750 760 770 780
pF1KSD NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
690 700 710 720 730 740
790 800 810 820 830 840
pF1KSD QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
750 760 770 780 790 800
850 860 870 880
pF1KSD RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_663 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
810 820 830 840 850
>>XP_006715747 (OMIM: 606732) PREDICTED: oxysterol-bindi (534 aa)
initn: 3600 init1: 3600 opt: 3600 Z-score: 3507.3 bits: 659.4 E(85289): 1.3e-188
Smith-Waterman score: 3600; 100.0% identity (100.0% similar) in 534 aa overlap (354-887:1-534)
330 340 350 360 370 380
pF1KSD ETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNA
::::::::::::::::::::::::::::::
XP_006 MSAEREKLKQLMEQDASSSPSAQVIGLKNA
10 20 30
390 400 410 420 430 440
pF1KSD LSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVHQLSNESRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVHQLSNESRLS
40 50 60 70 80 90
450 460 470 480 490 500
pF1KSD ITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLD
100 110 120 130 140 150
510 520 530 540 550 560
pF1KSD SGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEEL
160 170 180 190 200 210
570 580 590 600 610 620
pF1KSD EYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQ
220 230 240 250 260 270
630 640 650 660 670 680
pF1KSD FFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEW
280 290 300 310 320 330
690 700 710 720 730 740
pF1KSD NKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRS
340 350 360 370 380 390
750 760 770 780 790 800
pF1KSD GKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLL
400 410 420 430 440 450
810 820 830 840 850 860
pF1KSD PPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSW
460 470 480 490 500 510
870 880
pF1KSD VSNGTYLELRKDLGFSKLDHPVLW
::::::::::::::::::::::::
XP_006 VSNGTYLELRKDLGFSKLDHPVLW
520 530
>>NP_115912 (OMIM: 606734) oxysterol-binding protein-rel (934 aa)
initn: 3497 init1: 1970 opt: 3532 Z-score: 3437.3 bits: 647.2 E(85289): 1e-184
Smith-Waterman score: 3532; 59.2% identity (82.7% similar) in 873 aa overlap (33-887:68-934)
10 20 30 40 50 60
pF1KSD SDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLR-GEMNYTQEPPVQKGFLLKK
::::..:::. :. : .:.: ..::.:::
NP_115 ILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTN-VQKPDKHEGFMLKK
40 50 60 70 80 90
70 80 90 100 110 120
pF1KSD RKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEE
::::::::::::: ::.:.:::.:. ::.. :.:: :::::::::.::... :::::::
NP_115 RKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEE
100 110 120 130 140 150
130 140 150 160 170 180
pF1KSD HIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSIS
:::::::::.. :: :::::::::.::::::. :.... :.: ... ..:: .. :.
NP_115 HIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVM
160 170 180 190 200 210
190 200 210 220 230
pF1KSD SRKR--SSISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMS
. : .:. :. . .... .: :...: :::.::.:..:..:::::.. :::.:
NP_115 DGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELS
220 230 240 250 260 270
240 250 260 270 280 290
pF1KSD QLLQSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG
.:::....:.:: ::: .. .:.. . ::.:: ::::.....::.: :::: ::.
NP_115 KLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVP--FSA
280 290 300 310 320 330
300 310 320 330 340 350
pF1KSD ---PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFN
::::::::::: . ..: .. .: :.:....:.::..: ::.::. :.::::
NP_115 TMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFN
340 350 360 370 380 390
360 370 380 390 400
pF1KSD IMSAEREKLKQLM-EQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLD--
.. :.:::::.. ::: :.. :.:. :...::.:: ::..:. :: :::.::.. :
NP_115 SIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQV
400 410 420 430 440 450
410 420 430 440 450 460
pF1KSD -SPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEI
: . : :. .:. . : .:..::::::...:.:::::::::::: ::::::
NP_115 VSVNIIPSPDEAGEQIHV--SLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEA
460 470 480 490 500 510
470 480 490 500 510 520
pF1KSD SDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISL
:::.::.::.:::.: :: : . :: :. : .: .. ::.:::::::..:::.:
NP_115 SDDESYISDVSDNISEDNTSVADNISRQILNGELTGG-AFRNGRRACLPAPCPDTSNINL
520 530 540 550 560 570
530 540 550 560 570 580
pF1KSD WNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAF
:::::::::::::::.:::::::::::::.::::.:::::::::.. .: :::: ::::
NP_115 WNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAF
580 590 600 610 620 630
590 600 610 620 630 640
pF1KSD AISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFW
:.:.: :.:.::::::::::::::::::::::::.:::::::::::::::: ::.:::::
NP_115 AVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFW
640 650 660 670 680 690
650 660 670 680 690 700
pF1KSD QDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI
::.:::::::::::::.:.:: .: :: .::.. :::::.::::::::.::::::::..:
NP_115 QDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTI
700 710 720 730 740 750
710 720 730 740 750 760
pF1KSD KNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSAC
.: ... : ::..:.:..::..: .:..:.:.:. ::::.::::::::..::: . :. :
NP_115 RNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKC
760 770 780 790 800 810
770 780 790 800 810 820
pF1KSD VWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ
.:: . :: .:: ::.::.::.::::.:: :.::::::.::::::::::::::: : .
NP_115 IWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASE
820 830 840 850 860 870
830 840 850 860 870 880
pF1KSD KQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLELRKDLGFSKLDHP
:::.:.::: ::: .:::..:: :.::.: : ..:::: :: ::::: ::::.: :
NP_115 KQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSP
880 890 900 910 920 930
pF1KSD VLW
:::
NP_115 VLW
>>XP_016858761 (OMIM: 606734) PREDICTED: oxysterol-bindi (892 aa)
initn: 3438 init1: 1885 opt: 3236 Z-score: 3149.6 bits: 594.0 E(85289): 1.1e-168
Smith-Waterman score: 3412; 56.2% identity (78.6% similar) in 929 aa overlap (1-887:1-892)
10 20 30 40 50
pF1KSD MMSDEKNLGVSQKLVSPS-RS-TSSCSSKQGSRQ--DSWEVVEGLR-GEMNYTQEPPVQK
: ::::... ..: .:. :: .:: ::.. ::: ::::..:::. :. : .:.: ..
XP_016 MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQEADSWEIIEGLKIGQTN-VQKPDKHE
10 20 30 40 50
60 70 80 90 100 110
pF1KSD GFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCI
::.:::::::::::::::: ::.:.:::.:. ::.. :.:: :::::::::.::... :
XP_016 GFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD DLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSG
:::::::::::::::.. :: :::::::::.::::::. :.... :.: ... ..:: .
XP_016 DLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD VFDSISSRKR--SSISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHA
. :. . : .:. :. . .... .: :...: :::.::.:..:..:::::..
XP_016 ANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQS
180 190 200 210 220 230
240 250 260 270 280
pF1KSD YLVEMSQLLQSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKD-------
:::.:.:::....:.:: ::: .. .:.. . ::.:: ::::.....::
XP_016 NLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQE
240 250 260 270 280 290
290 300 310 320
pF1KSD ---AKGTLQVPK-------------PFSG---PVRLHSSNPNL-STLDFGEEKNY-SDGS
::: ... . :::. ::::::::::: . ..: .. .:
XP_016 GPPAKGQFSTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KSD ETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKN
:.:....:.::..: ::.::. :.:::: .. :.:::::.. ::: :.. :.:. :..
XP_016 ESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQ
360 370 380 390 400 410
390 400 410 420 430 440
pF1KSD ALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVHQLSNESRL
.::.: : ::. :: : : .:..:::::
XP_016 SLSQAGEQ----------IHV-SL----P--------------------LSQQVANESRL
420 430 440
450 460 470 480 490 500
pF1KSD SITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVL
:...:.:::::::::::: :::::: :::.::.::.:::.: :: : . :: :. :
XP_016 SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGEL
450 460 470 480 490 500
510 520 530 540 550 560
pF1KSD DSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEE
.: .. ::.:::::::..:::.::::::::::::::::.:::::::::::::.::::
XP_016 TGG-AFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEE
510 520 530 540 550 560
570 580 590 600 610 620
pF1KSD LEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGF
.:::::::::.. .: :::: :::::.:.: :.:.::::::::::::::::::::::::
XP_016 MEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGF
570 580 590 600 610 620
630 640 650 660 670 680
pF1KSD QFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFE
.:::::::::::::::: ::.:::::::.:::::::::::::.:.:: .: :: .::..
XP_016 RFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYV
630 640 650 660 670 680
690 700 710 720 730 740
pF1KSD WNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDR
:::::.::::::::.::::::::..:.: ... : ::..:.:..::..: .:..:.:.:.
XP_016 WNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQ
690 700 710 720 730 740
750 760 770 780 790 800
pF1KSD SGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSL
::::.::::::::..::: . :. :.:: . :: .:: ::.::.::.::::.:: :.:
XP_016 EGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDL
750 760 770 780 790 800
810 820 830 840 850 860
pF1KSD LPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD--
:::::.::::::::::::::: : .:::.:.::: ::: .:::..:: :.::.: :
XP_016 LPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDAN
810 820 830 840 850 860
870 880
pF1KSD --DSWVSNGTYLELRKDLGFSKLDHPVLW
..:::: :: ::::: ::::.: ::::
XP_016 QREAWVSNDTYWELRKDPGFSKVDSPVLW
870 880 890
887 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:40:23 2016 done: Thu Nov 3 18:40:25 2016
Total Scan time: 13.860 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]