FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0717, 727 aa 1>>>pF1KSDA0717 727 - 727 aa - 727 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2151+/-0.000329; mu= 18.9125+/- 0.021 mean_var=148.8133+/-30.044, 0's: 0 Z-trim(120.5): 87 B-trim: 363 in 1/58 Lambda= 0.105136 statistics sampled from 35750 (35846) to 35750 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.42), width: 16 Scan time: 9.780 The best scores are: opt bits E(85289) NP_055993 (OMIM: 607352) rho-related BTB domain-co ( 727) 4989 768.7 0 NP_001153509 (OMIM: 607352) rho-related BTB domain ( 734) 4989 768.8 0 XP_016868740 (OMIM: 607352) PREDICTED: rho-related ( 749) 4989 768.8 0 NP_001153508 (OMIM: 607352) rho-related BTB domain ( 749) 4989 768.8 0 XP_011538730 (OMIM: 607351) PREDICTED: rho-related ( 530) 1814 287.0 1.3e-76 XP_011538728 (OMIM: 607351) PREDICTED: rho-related ( 611) 1814 287.1 1.4e-76 XP_016872491 (OMIM: 607351) PREDICTED: rho-related ( 621) 1814 287.1 1.5e-76 XP_011538727 (OMIM: 607351) PREDICTED: rho-related ( 621) 1814 287.1 1.5e-76 XP_006718147 (OMIM: 607351) PREDICTED: rho-related ( 696) 1814 287.1 1.6e-76 XP_011538726 (OMIM: 607351) PREDICTED: rho-related ( 696) 1814 287.1 1.6e-76 NP_001229288 (OMIM: 607351) rho-related BTB domain ( 696) 1814 287.1 1.6e-76 XP_016872489 (OMIM: 607351) PREDICTED: rho-related ( 696) 1814 287.1 1.6e-76 NP_055651 (OMIM: 607351) rho-related BTB domain-co ( 696) 1814 287.1 1.6e-76 XP_006718148 (OMIM: 607351) PREDICTED: rho-related ( 696) 1814 287.1 1.6e-76 XP_016872490 (OMIM: 607351) PREDICTED: rho-related ( 696) 1814 287.1 1.6e-76 XP_016872495 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 XP_016872496 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 XP_016872494 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 XP_016872492 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 XP_016872493 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 XP_016872497 (OMIM: 607351) PREDICTED: rho-related ( 576) 1509 240.8 1.2e-62 NP_001300870 (OMIM: 165390) transforming protein R ( 193) 385 69.7 1.2e-11 NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 385 69.7 1.2e-11 NP_061485 (OMIM: 602048) ras-related C3 botulinum ( 211) 369 67.4 6.9e-11 NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 365 66.7 9.8e-11 NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 365 66.7 9.8e-11 NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 354 65.0 3.1e-10 NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 354 65.0 3.1e-10 NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 354 65.0 3.1e-10 NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 351 64.6 4.3e-10 XP_016864725 (OMIM: 607353) PREDICTED: rho-related ( 417) 352 65.1 6.4e-10 XP_016864726 (OMIM: 607353) PREDICTED: rho-related ( 417) 352 65.1 6.4e-10 NP_001300873 (OMIM: 165390) transforming protein R ( 173) 345 63.6 7.5e-10 NP_055714 (OMIM: 607353) rho-related BTB domain-co ( 611) 352 65.3 8.2e-10 NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 341 63.1 1.2e-09 XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 341 63.1 1.2e-09 XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 341 63.1 1.2e-09 NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 332 61.7 3.2e-09 XP_011541581 (OMIM: 607353) PREDICTED: rho-related ( 489) 336 62.8 3.8e-09 NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 327 60.9 5.3e-09 NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 327 61.0 5.7e-09 NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 326 60.8 5.9e-09 NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 326 60.8 5.9e-09 NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 307 57.9 4.6e-08 NP_001300874 (OMIM: 165390) transforming protein R ( 112) 296 56.0 9.8e-08 XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 294 55.8 1.5e-07 XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 295 56.1 1.6e-07 NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 295 56.2 1.7e-07 XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 295 56.2 1.8e-07 NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 292 55.8 2.6e-07 >>NP_055993 (OMIM: 607352) rho-related BTB domain-contai (727 aa) initn: 4989 init1: 4989 opt: 4989 Z-score: 4097.4 bits: 768.7 E(85289): 0 Smith-Waterman score: 4989; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:1-727) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 670 680 690 700 710 720 pF1KSD SSSSAVV ::::::: NP_055 SSSSAVV >>NP_001153509 (OMIM: 607352) rho-related BTB domain-con (734 aa) initn: 4989 init1: 4989 opt: 4989 Z-score: 4097.3 bits: 768.8 E(85289): 0 Smith-Waterman score: 4989; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:8-734) 10 20 30 40 50 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD WAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD SLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD GREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD DLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD AGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMV 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD VVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAF 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD MNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPF 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD VESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQY 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD TVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD SPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSS 670 680 690 700 710 720 720 pF1KSD AASSSSPSSSSAVV :::::::::::::: NP_001 AASSSSPSSSSAVV 730 >>XP_016868740 (OMIM: 607352) PREDICTED: rho-related BTB (749 aa) initn: 4989 init1: 4989 opt: 4989 Z-score: 4097.2 bits: 768.8 E(85289): 0 Smith-Waterman score: 4989; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:23-749) 10 20 30 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA :::::::::::::::::::::::::::::::::::::: XP_016 MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK 670 680 690 700 710 720 700 710 720 pF1KSD RRWLFWNSPSSPSSSAASSSSPSSSSAVV ::::::::::::::::::::::::::::: XP_016 RRWLFWNSPSSPSSSAASSSSPSSSSAVV 730 740 >>NP_001153508 (OMIM: 607352) rho-related BTB domain-con (749 aa) initn: 4989 init1: 4989 opt: 4989 Z-score: 4097.2 bits: 768.8 E(85289): 0 Smith-Waterman score: 4989; 100.0% identity (100.0% similar) in 727 aa overlap (1-727:23-749) 10 20 30 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA :::::::::::::::::::::::::::::::::::::: NP_001 MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK 670 680 690 700 710 720 700 710 720 pF1KSD RRWLFWNSPSSPSSSAASSSSPSSSSAVV ::::::::::::::::::::::::::::: NP_001 RRWLFWNSPSSPSSSAASSSSPSSSSAVV 730 740 >>XP_011538730 (OMIM: 607351) PREDICTED: rho-related BTB (530 aa) initn: 2532 init1: 1811 opt: 1814 Z-score: 1496.3 bits: 287.0 E(85289): 1.3e-76 Smith-Waterman score: 2541; 70.0% identity (86.6% similar) in 544 aa overlap (1-540:1-525) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_011 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_011 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_011 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_011 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_011 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ..... .::: : : : : .:. : XP_011 EES-------PNGS-----EGACEKEKQ------SRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_011 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_011 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_011 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. : XP_011 ANSESRPHP 530 >>XP_011538728 (OMIM: 607351) PREDICTED: rho-related BTB (611 aa) initn: 2755 init1: 1811 opt: 1814 Z-score: 1495.6 bits: 287.1 E(85289): 1.4e-76 Smith-Waterman score: 2726; 68.4% identity (86.0% similar) in 598 aa overlap (1-594:1-579) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_011 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_011 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_011 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_011 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_011 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ..... .::: : : : : .:. : XP_011 EES-------PNGS-----EGACEKEKQ------SRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_011 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_011 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_011 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. :: .: .: :.:::.:::: ... . ::: ..:: ::::.::::::::.. .. XP_011 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALADLFSWE 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE XP_011 AEAGLHRIYELKCLSLEFRSSASFTLHQRS 590 600 610 >>XP_016872491 (OMIM: 607351) PREDICTED: rho-related BTB (621 aa) initn: 2806 init1: 1811 opt: 1814 Z-score: 1495.5 bits: 287.1 E(85289): 1.5e-76 Smith-Waterman score: 2807; 68.1% identity (85.4% similar) in 624 aa overlap (1-620:1-605) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_016 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_016 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_016 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_016 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_016 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ..... .::: : : : : .:. : XP_016 EES-------PNGS-----EGACEKEKQ------SRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_016 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_016 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_016 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. :: .: .: :.:::.:::: ... . ::: ..:: ::::.::::::::.::..: XP_016 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE : .:. : :::.:: .::::: XP_016 ELTKAATSGVGIDGEVLSYLELAQTTRNTSSGTAGPLCGT 590 600 610 620 >>XP_011538727 (OMIM: 607351) PREDICTED: rho-related BTB (621 aa) initn: 2806 init1: 1811 opt: 1814 Z-score: 1495.5 bits: 287.1 E(85289): 1.5e-76 Smith-Waterman score: 2807; 68.1% identity (85.4% similar) in 624 aa overlap (1-620:1-605) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_011 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_011 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_011 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_011 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_011 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ..... .::: : : : : .:. : XP_011 EES-------PNGS-----EGACEKEKQ------SRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_011 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_011 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_011 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. :: .: .: :.:::.:::: ... . ::: ..:: ::::.::::::::.::..: XP_011 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE : .:. : :::.:: .::::: XP_011 ELTKAATSGVGIDGEVLSYLELAQTTRNTSSGTAGPLCGT 590 600 610 620 >>XP_006718147 (OMIM: 607351) PREDICTED: rho-related BTB (696 aa) initn: 3279 init1: 1811 opt: 1814 Z-score: 1494.9 bits: 287.1 E(85289): 1.6e-76 Smith-Waterman score: 3282; 68.0% identity (85.3% similar) in 715 aa overlap (1-711:1-694) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_006 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_006 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_006 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_006 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_006 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ... ...::: : : : : .:. : XP_006 EES-------PNGS-----EGACEKE------KQSRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_006 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_006 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_006 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. :: .: .: :.:::.:::: ... . ::: ..:: ::::.::::::::.::..: XP_006 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE : .:. : :::.:: .::::::: :.::: :::::::::::.:: :: ...:. : . XP_006 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 590 600 610 620 630 640 660 670 680 690 700 710 pF1KSD NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAAS ::::::.:::::::::::::::::...:::::: :.. .:.: :::: ::. XP_006 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS--SPAVA 650 660 670 680 690 720 pF1KSD SSSPSSSSAVV >>XP_011538726 (OMIM: 607351) PREDICTED: rho-related BTB (696 aa) initn: 3279 init1: 1811 opt: 1814 Z-score: 1494.9 bits: 287.1 E(85289): 1.6e-76 Smith-Waterman score: 3282; 68.0% identity (85.3% similar) in 715 aa overlap (1-711:1-694) 10 20 30 40 50 60 pF1KSD MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR ::.::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: XP_011 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT ::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:::. XP_011 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE ::::::::::::.::::::::::::::::::::::::::::::: ..::::::::::::: XP_011 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP ::.::::::: :::::::::::::::::::::::::::::..::.::::::::::: :: XP_011 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL :.: .:. :: . . : ::..::::::...::.. .::::.:::.::::::::::::. XP_011 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- :. :.:. .: ... ...::: : : : : .:. : XP_011 EES-------PNGS-----EGACEKE------KQSRDFQGRILSVDPEEEREEGPPRIPQ 310 320 330 340 360 370 380 390 400 410 pF1KSD AGLRASTSDGILRGNGT---GYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK : :.. ..... : : .: . ..:..::..:.....:: .:.. . :.::. XP_011 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 350 360 370 380 390 400 420 430 440 450 460 470 pF1KSD MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ ::.:.::::::..:..::::.:::.:.::. .:.:::.::.::::::: ::.:.:::::: XP_011 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 410 420 430 440 450 460 480 490 500 510 520 530 pF1KSD EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES :::::::::..::.::::.::::::::: ::::.::::::::: ::.:::::::: :::: XP_011 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 470 480 490 500 510 520 540 550 560 570 580 590 pF1KSD STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT .. :: .: .: :.:::.:::: ... . ::: ..:: ::::.::::::::.::..: XP_011 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE : .:. : :::.:: .::::::: :.::: :::::::::::.:: :: ...:. : . XP_011 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 590 600 610 620 630 640 660 670 680 690 700 710 pF1KSD NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAAS ::::::.:::::::::::::::::...:::::: :.. .:.: :::: ::. XP_011 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS--SPAVA 650 660 670 680 690 720 pF1KSD SSSPSSSSAVV 727 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:46:16 2016 done: Thu Nov 3 02:46:18 2016 Total Scan time: 9.780 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]