FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0719, 608 aa 1>>>pF1KSDA0719 608 - 608 aa - 608 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8611+/-0.000402; mu= 14.1426+/- 0.025 mean_var=143.7290+/-29.151, 0's: 0 Z-trim(117.0): 109 B-trim: 334 in 1/53 Lambda= 0.106980 statistics sampled from 28434 (28550) to 28434 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.335), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) NP_055635 (OMIM: 606081) mitochondrial import rece ( 608) 4004 629.9 7.5e-180 NP_003305 (OMIM: 601963) tetratricopeptide repeat ( 292) 262 52.1 3.2e-06 NP_001269429 (OMIM: 601963) tetratricopeptide repe ( 292) 262 52.1 3.2e-06 XP_011515547 (OMIM: 603395,615505) PREDICTED: sper ( 487) 247 50.0 2.3e-05 NP_001139548 (OMIM: 611477) RNA polymerase II-asso ( 506) 244 49.5 3.2e-05 XP_016869244 (OMIM: 603395,615505) PREDICTED: sper ( 814) 247 50.2 3.3e-05 XP_011515543 (OMIM: 603395,615505) PREDICTED: sper ( 871) 247 50.2 3.5e-05 XP_011515542 (OMIM: 603395,615505) PREDICTED: sper ( 875) 247 50.2 3.5e-05 XP_011515544 (OMIM: 603395,615505) PREDICTED: sper ( 926) 247 50.2 3.7e-05 NP_003105 (OMIM: 603395,615505) sperm-associated a ( 926) 247 50.2 3.7e-05 NP_757367 (OMIM: 603395,615505) sperm-associated a ( 926) 247 50.2 3.7e-05 XP_011515545 (OMIM: 603395,615505) PREDICTED: sper ( 926) 247 50.2 3.7e-05 XP_016869243 (OMIM: 603395,615505) PREDICTED: sper ( 961) 247 50.2 3.8e-05 NP_078880 (OMIM: 611477) RNA polymerase II-associa ( 665) 244 49.6 4e-05 NP_001139547 (OMIM: 611477) RNA polymerase II-asso ( 631) 242 49.3 4.7e-05 XP_005260311 (OMIM: 616049) PREDICTED: mitochondri ( 207) 233 47.5 5.5e-05 XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 237 48.4 6.2e-05 XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 237 48.4 6.2e-05 XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 237 48.4 6.2e-05 XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 237 48.4 6.2e-05 NP_001138238 (OMIM: 601964) dnaJ homolog subfamily ( 438) 237 48.4 6.2e-05 NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 237 48.4 6.7e-05 XP_011526803 (OMIM: 616049) PREDICTED: mitochondri ( 283) 233 47.6 6.9e-05 NP_006800 (OMIM: 616049) mitochondrial import rece ( 309) 233 47.6 7.3e-05 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 224 46.4 0.00026 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 224 46.4 0.00027 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 224 46.5 0.00029 NP_001265518 (OMIM: 606796) hsc70-interacting prot ( 359) 217 45.2 0.00045 NP_003923 (OMIM: 606796) hsc70-interacting protein ( 369) 216 45.1 0.00051 NP_001269582 (OMIM: 605063) stress-induced-phospho ( 519) 213 44.8 0.00091 NP_006810 (OMIM: 605063) stress-induced-phosphopro ( 543) 213 44.8 0.00094 NP_001269581 (OMIM: 605063) stress-induced-phospho ( 590) 213 44.8 0.001 NP_005852 (OMIM: 607207,615768) E3 ubiquitin-prote ( 303) 202 42.8 0.002 NP_001295210 (OMIM: 611220,616279) protein unc-45 ( 850) 207 44.0 0.0025 XP_016879723 (OMIM: 611220,616279) PREDICTED: prot ( 850) 207 44.0 0.0025 NP_001253981 (OMIM: 611220,616279) protein unc-45 ( 929) 207 44.0 0.0026 NP_001028748 (OMIM: 611220,616279) protein unc-45 ( 929) 207 44.0 0.0026 NP_775259 (OMIM: 611220,616279) protein unc-45 hom ( 931) 207 44.0 0.0027 NP_060338 (OMIM: 610732) tetratricopeptide repeat ( 705) 194 41.9 0.0087 XP_016873439 (OMIM: 610732) PREDICTED: tetratricop ( 753) 194 42.0 0.0091 XP_016873438 (OMIM: 610732) PREDICTED: tetratricop ( 755) 194 42.0 0.0091 XP_016873437 (OMIM: 610732) PREDICTED: tetratricop ( 760) 194 42.0 0.0092 XP_016873436 (OMIM: 610732) PREDICTED: tetratricop ( 774) 194 42.0 0.0093 XP_016873434 (OMIM: 610732) PREDICTED: tetratricop ( 777) 194 42.0 0.0093 XP_016873433 (OMIM: 610732) PREDICTED: tetratricop ( 777) 194 42.0 0.0093 XP_016873435 (OMIM: 610732) PREDICTED: tetratricop ( 777) 194 42.0 0.0093 XP_016873432 (OMIM: 610732) PREDICTED: tetratricop ( 777) 194 42.0 0.0093 XP_005271661 (OMIM: 610732) PREDICTED: tetratricop ( 777) 194 42.0 0.0093 >>NP_055635 (OMIM: 606081) mitochondrial import receptor (608 aa) initn: 4004 init1: 4004 opt: 4004 Z-score: 3349.9 bits: 629.9 E(85289): 7.5e-180 Smith-Waterman score: 4004; 100.0% identity (100.0% similar) in 608 aa overlap (1-608:1-608) 10 20 30 40 50 60 pF1KSD MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKK 550 560 570 580 590 600 pF1KSD YGLKPPTL :::::::: NP_055 YGLKPPTL >>NP_003305 (OMIM: 601963) tetratricopeptide repeat prot (292 aa) initn: 255 init1: 255 opt: 262 Z-score: 232.8 bits: 52.1 E(85289): 3.2e-06 Smith-Waterman score: 262; 39.6% identity (74.0% similar) in 96 aa overlap (118-213:120-215) 90 100 110 120 130 140 pF1KSD GRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTE :..::. :: : : .: . :..:. .::. NP_003 SELDEEYLIELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSC 90 100 110 120 130 140 150 160 170 180 190 200 pF1KSD KNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECL . . : ...::::: . .: . . .::.::..:::.:..:..:::. .:: :. : : NP_003 FQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEAL 150 160 170 180 190 200 210 220 230 240 250 260 pF1KSD EDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDD :: .. NP_003 EDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENF 210 220 230 240 250 260 >>NP_001269429 (OMIM: 601963) tetratricopeptide repeat p (292 aa) initn: 255 init1: 255 opt: 262 Z-score: 232.8 bits: 52.1 E(85289): 3.2e-06 Smith-Waterman score: 262; 39.6% identity (74.0% similar) in 96 aa overlap (118-213:120-215) 90 100 110 120 130 140 pF1KSD GRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTE :..::. :: : : .: . :..:. .::. NP_001 SELDEEYLIELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSC 90 100 110 120 130 140 150 160 170 180 190 200 pF1KSD KNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECL . . : ...::::: . .: . . .::.::..:::.:..:..:::. .:: :. : : NP_001 FQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEAL 150 160 170 180 190 200 210 220 230 240 250 260 pF1KSD EDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDD :: .. NP_001 EDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENF 210 220 230 240 250 260 >>XP_011515547 (OMIM: 603395,615505) PREDICTED: sperm-as (487 aa) initn: 289 init1: 160 opt: 247 Z-score: 217.3 bits: 50.0 E(85289): 2.3e-05 Smith-Waterman score: 247; 37.2% identity (65.9% similar) in 129 aa overlap (114-242:209-331) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: XP_011 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 180 190 200 210 220 230 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. XP_011 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 240 250 260 270 280 290 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSS .: ::.. : .: .. . :.. : ..: :.: XP_011 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG 300 310 320 330 340 350 270 280 290 300 310 320 pF1KSD FTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDA XP_011 KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEA 360 370 380 390 400 410 >>NP_001139548 (OMIM: 611477) RNA polymerase II-associat (506 aa) initn: 190 init1: 145 opt: 244 Z-score: 214.6 bits: 49.5 E(85289): 3.2e-05 Smith-Waterman score: 244; 38.2% identity (67.5% similar) in 123 aa overlap (113-235:122-238) 90 100 110 120 130 140 pF1KSD RKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAIS .: . :..:: .:: ::::.::.:::..:. NP_001 KENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA 100 110 120 130 140 150 150 160 170 180 190 200 pF1KSD LCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDN :. : . ::: :. ..::..:. .:::.:. :. .: ::. ::. :. : . NP_001 --ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGK 160 170 180 190 200 210 220 230 240 250 260 pF1KSD KKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFS .: .: .: .:: :.:.. .:. : : NP_001 LNEAKQDFETVLLLEP-GNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPP 210 220 230 240 250 260 270 280 290 300 310 320 pF1KSD SFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEID NP_001 HPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDD 270 280 290 300 310 320 >>XP_016869244 (OMIM: 603395,615505) PREDICTED: sperm-as (814 aa) initn: 381 init1: 160 opt: 247 Z-score: 214.4 bits: 50.2 E(85289): 3.3e-05 Smith-Waterman score: 339; 26.4% identity (55.2% similar) in 382 aa overlap (25-398:249-610) 10 20 30 40 50 pF1KSD MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGT-GGLPRWQLALAVGAPLLLGA ::: :. .: : ..: . XP_016 ETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLT 220 230 240 250 260 270 60 70 80 90 100 110 pF1KSD GAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEG-PGAHLDMNSLD : .: : ::. .: . : :.. . :. . ..::: : :: . XP_016 GKAEGGKRPARGAPQRGQTPEAGADKRSPRRASAAAAAGGGATGHPGGGQGA-------E 280 290 300 310 320 330 120 130 140 150 160 pF1KSD RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLC-PTEKNV--DLSTFYQNRAAAFEQLQKW . :..::. :..:.. .: :. ::.: :. ... ::: .:.:::: . . . XP_016 NPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNC 340 350 360 370 380 390 170 180 190 200 210 220 pF1KSD KEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-GFQ-NQQSMLL . :::..:.::.: .: :.::: :.: :.. . : .: .. :.: ..:. XP_016 SGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNR 400 410 420 430 440 450 230 240 250 260 270 280 pF1KSD ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEG ...: : . .:: . : .:. .... . ..::. :..:.. . .: XP_016 LSRILMELDGPNWREKL-SPIPAVPASVPLQAWHPA--KEMISKQ--AGDSSSHRQ--QG 460 470 480 490 500 290 300 310 320 330 340 pF1KSD EALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANA . : .. ...: ....:: .:. :. . ..: : :: :: . . . XP_016 ITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-IYTNRALCYLKLCQFEE 510 520 530 540 550 560 350 360 370 380 390 400 pF1KSD AKPDLDKVISLKEANVK-LRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHH :: : :....: ..::: . :: ..: .:. : :.: . .:: XP_016 AKQDCDQALQLADGNVKAFYRRALAHKGLKNYQK-----SLIDLNKVILLDPSIIEAKME 570 580 590 600 610 410 420 430 440 450 460 pF1KSD RGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFE XP_016 LEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGKSSR 620 630 640 650 660 670 >-- initn: 342 init1: 160 opt: 247 Z-score: 214.4 bits: 50.2 E(85289): 3.3e-05 Smith-Waterman score: 247; 37.2% identity (65.9% similar) in 129 aa overlap (114-242:97-219) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: XP_016 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 70 80 90 100 110 120 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. XP_016 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 130 140 150 160 170 180 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSS .: ::.. : .: .. . :.. : ..: :.: XP_016 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG 190 200 210 220 230 240 270 280 290 300 310 320 pF1KSD FTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDA XP_016 KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEA 250 260 270 280 290 300 >>XP_011515543 (OMIM: 603395,615505) PREDICTED: sperm-as (871 aa) initn: 321 init1: 160 opt: 247 Z-score: 214.0 bits: 50.2 E(85289): 3.5e-05 Smith-Waterman score: 327; 26.5% identity (55.9% similar) in 358 aa overlap (25-374:361-703) 10 20 30 40 50 pF1KSD MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGT-GGLPRWQLALAVGAPLLLGA ::: :. .: : ..: . XP_011 ETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLT 340 350 360 370 380 390 60 70 80 90 100 110 pF1KSD GAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEG-PGAHLDMNSLD : .: : ::. .: . : :.. . :. . ..::: : :: . XP_011 GKAEGGKRPARGAPQRGQTPEAGADKRSPRRASAAAAAGGGATGHPGGGQGA-------E 400 410 420 430 440 120 130 140 150 160 pF1KSD RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLC-PTEKNV--DLSTFYQNRAAAFEQLQKW . :..::. :..:.. .: :. ::.: :. ... ::: .:.:::: . . . XP_011 NPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNC 450 460 470 480 490 500 170 180 190 200 210 220 pF1KSD KEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-GFQ-NQQSMLL . :::..:.::.: .: :.::: :.: :.. . : .: .. :.: ..:. XP_011 SGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNR 510 520 530 540 550 560 230 240 250 260 270 280 pF1KSD ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEG ...: : . .:: . : .:. .... . ..::. :..:.. . .: XP_011 LSRILMELDGPNWREKLSPI-PAVPASVPLQAWHPA--KEMISKQA--GDSSSHRQ--QG 570 580 590 600 610 290 300 310 320 330 340 pF1KSD EALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANA . : .. ...: ....:: .:. :. . ..: : :: :: . . . XP_011 ITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-IYTNRALCYLKLCQFEE 620 630 640 650 660 670 350 360 370 380 390 400 pF1KSD AKPDLDKVISLKEANVK-LRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHH :: : :....: ..::: . :: ..: XP_011 AKQDCDQALQLADGNVKAFYRRALAHKGLKVNEGKEEPGRPAGEVSMGCLASEKGGKSSR 680 690 700 710 720 730 >-- initn: 342 init1: 160 opt: 247 Z-score: 214.0 bits: 50.2 E(85289): 3.5e-05 Smith-Waterman score: 247; 37.2% identity (65.9% similar) in 129 aa overlap (114-242:209-331) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: XP_011 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 180 190 200 210 220 230 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. XP_011 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 240 250 260 270 280 290 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSS .: ::.. : .: .. . :.. : ..: :.: XP_011 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG 300 310 320 330 340 350 270 280 290 300 310 320 pF1KSD FTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDA XP_011 KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEA 360 370 380 390 400 410 >>XP_011515542 (OMIM: 603395,615505) PREDICTED: sperm-as (875 aa) initn: 381 init1: 160 opt: 247 Z-score: 214.0 bits: 50.2 E(85289): 3.5e-05 Smith-Waterman score: 261; 22.9% identity (53.8% similar) in 507 aa overlap (114-589:209-691) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: XP_011 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 180 190 200 210 220 230 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. XP_011 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 240 250 260 270 280 290 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKE-KYKNREPLMPSPQFIKSYFS .: ::.. : .: .. . :.. : ..: :.: . :... .. : :.. XP_011 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVI---QEIEN--- 300 310 320 330 340 270 280 290 300 310 pF1KSD SFTDDIISQPMLKGEKSDEDK---DKEGEALEVKENS-GYLKAKQYMEEENYDKIISECS ..: .. : : . :: . : : .. : .. : . :. . XP_011 --SEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAP 350 360 370 380 390 400 320 330 340 350 360 370 pF1KSD KEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYM .. .. . ::. :.. ...: . . . :..: ..: :.. :.. XP_011 QRGQTPEAGADKRSPRRASAAAAAGGGATGHPGGGQG-AENPAGLKSQGNELFRSGQFAE 410 420 430 440 450 460 380 390 400 410 420 pF1KSD QQQQ-----PLLSTQDFNMAADID---PQNADVYHHRGQLKILL---DQVEEAVADFD-- . :: ..: :.. . : : ..:. . . ... . . ..: XP_011 AAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRLSRILMELDGP 470 480 490 500 510 520 430 440 450 460 470 pF1KSD ------ECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGY : : :. :: . . . .:..::. : .. :...: . . :: XP_011 NWREKLSPIPAVPASVPLQAWHPAKEMISKQAGDSSSHRQQGITD-EKTFKALKE--EG- 530 540 550 560 570 480 490 500 510 520 530 pF1KSD ALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQW------KQDLDRGLEL : ..:.. . : :..:. .. . . :....: :. ::: :..:.: XP_011 ---NQCVNDKN-YKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQL 580 590 600 610 620 630 540 550 560 570 580 590 pF1KSD ISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEME-MAHLYSLCDAAH . .. . .:.. . . . . ...:.: ... .: :: :.: ...: .: : XP_011 ADGNVKAFYRRALAHKGLKNYQKSLIDLNKVI-LLDPSIIEAKMELEEVTRLLNLKDKTA 640 650 660 670 680 690 600 pF1KSD AQTEVAKKYGLKPPTL XP_011 PFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGKSSRSPEDPEKLPIAKPNN 700 710 720 730 740 750 >>XP_011515544 (OMIM: 603395,615505) PREDICTED: sperm-as (926 aa) initn: 381 init1: 160 opt: 247 Z-score: 213.7 bits: 50.2 E(85289): 3.7e-05 Smith-Waterman score: 339; 26.4% identity (55.2% similar) in 382 aa overlap (25-398:361-722) 10 20 30 40 50 pF1KSD MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGT-GGLPRWQLALAVGAPLLLGA ::: :. .: : ..: . XP_011 ETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLT 340 350 360 370 380 390 60 70 80 90 100 110 pF1KSD GAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEG-PGAHLDMNSLD : .: : ::. .: . : :.. . :. . ..::: : :: . XP_011 GKAEGGKRPARGAPQRGQTPEAGADKRSPRRASAAAAAGGGATGHPGGGQGA-------E 400 410 420 430 440 120 130 140 150 160 pF1KSD RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLC-PTEKNV--DLSTFYQNRAAAFEQLQKW . :..::. :..:.. .: :. ::.: :. ... ::: .:.:::: . . . XP_011 NPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNC 450 460 470 480 490 500 170 180 190 200 210 220 pF1KSD KEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-GFQ-NQQSMLL . :::..:.::.: .: :.::: :.: :.. . : .: .. :.: ..:. XP_011 SGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNR 510 520 530 540 550 560 230 240 250 260 270 280 pF1KSD ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEG ...: : . .:: . : .:. .... . ..::. :..:.. . .: XP_011 LSRILMELDGPNWREKL-SPIPAVPASVPLQAWHPA--KEMISKQ--AGDSSSHRQ--QG 570 580 590 600 610 290 300 310 320 330 340 pF1KSD EALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANA . : .. ...: ....:: .:. :. . ..: : :: :: . . . XP_011 ITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-IYTNRALCYLKLCQFEE 620 630 640 650 660 670 350 360 370 380 390 400 pF1KSD AKPDLDKVISLKEANVK-LRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHH :: : :....: ..::: . :: ..: .:. : :.: . .:: XP_011 AKQDCDQALQLADGNVKAFYRRALAHKGLKNYQK-----SLIDLNKVILLDPSIIEAKME 680 690 700 710 720 730 410 420 430 440 450 460 pF1KSD RGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFE XP_011 LEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGKSSR 740 750 760 770 780 790 >-- initn: 342 init1: 160 opt: 247 Z-score: 213.7 bits: 50.2 E(85289): 3.7e-05 Smith-Waterman score: 247; 37.2% identity (65.9% similar) in 129 aa overlap (114-242:209-331) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: XP_011 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 180 190 200 210 220 230 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. XP_011 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 240 250 260 270 280 290 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSS .: ::.. : .: .. . :.. : ..: :.: XP_011 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG 300 310 320 330 340 350 270 280 290 300 310 320 pF1KSD FTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDA XP_011 KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEA 360 370 380 390 400 410 >>NP_003105 (OMIM: 603395,615505) sperm-associated antig (926 aa) initn: 381 init1: 160 opt: 247 Z-score: 213.7 bits: 50.2 E(85289): 3.7e-05 Smith-Waterman score: 339; 26.4% identity (55.2% similar) in 382 aa overlap (25-398:361-722) 10 20 30 40 50 pF1KSD MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGT-GGLPRWQLALAVGAPLLLGA ::: :. .: : ..: . NP_003 ETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLT 340 350 360 370 380 390 60 70 80 90 100 110 pF1KSD GAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEG-PGAHLDMNSLD : .: : ::. .: . : :.. . :. . ..::: : :: . NP_003 GKAEGGKRPARGAPQRGQTPEAGADKRSPRRASAAAAAGGGATGHPGGGQGA-------E 400 410 420 430 440 120 130 140 150 160 pF1KSD RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLC-PTEKNV--DLSTFYQNRAAAFEQLQKW . :..::. :..:.. .: :. ::.: :. ... ::: .:.:::: . . . NP_003 NPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNC 450 460 470 480 490 500 170 180 190 200 210 220 pF1KSD KEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-GFQ-NQQSMLL . :::..:.::.: .: :.::: :.: :.. . : .: .. :.: ..:. NP_003 SGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNR 510 520 530 540 550 560 230 240 250 260 270 280 pF1KSD ADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEG ...: : . .:: . : .:. .... . ..::. :..:.. . .: NP_003 LSRILMELDGPNWREKL-SPIPAVPASVPLQAWHPA--KEMISKQ--AGDSSSHRQ--QG 570 580 590 600 610 290 300 310 320 330 340 pF1KSD EALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANA . : .. ...: ....:: .:. :. . ..: : :: :: . . . NP_003 ITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-IYTNRALCYLKLCQFEE 620 630 640 650 660 670 350 360 370 380 390 400 pF1KSD AKPDLDKVISLKEANVK-LRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHH :: : :....: ..::: . :: ..: .:. : :.: . .:: NP_003 AKQDCDQALQLADGNVKAFYRRALAHKGLKNYQK-----SLIDLNKVILLDPSIIEAKME 680 690 700 710 720 730 410 420 430 440 450 460 pF1KSD RGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFE NP_003 LEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGKSSR 740 750 760 770 780 790 >-- initn: 342 init1: 160 opt: 247 Z-score: 213.7 bits: 50.2 E(85289): 3.7e-05 Smith-Waterman score: 247; 37.2% identity (65.9% similar) in 129 aa overlap (114-242:209-331) 90 100 110 120 130 140 pF1KSD KTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISL : :.:::. :..: ::.:.. ::..:: NP_003 EKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISA 180 190 200 210 220 230 150 160 170 180 190 200 pF1KSD CPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNK :: . :.::: : .::.:. . ::: :..::.: ::::.::: .... .. NP_003 LPT------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKL 240 250 260 270 280 290 210 220 230 240 250 260 pF1KSD KECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSS .: ::.. : .: .. . :.. : ..: :.: NP_003 REATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEG 300 310 320 330 340 350 270 280 290 300 310 320 pF1KSD FTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDA NP_003 KSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQKKLTGKAEGGKRPARGAPQRGQTPEA 360 370 380 390 400 410 608 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:46:51 2016 done: Thu Nov 3 02:46:53 2016 Total Scan time: 9.120 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]