FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0769, 684 aa 1>>>pF1KSDA0769 684 - 684 aa - 684 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2625+/-0.00111; mu= 3.5372+/- 0.067 mean_var=252.6291+/-52.881, 0's: 0 Z-trim(111.7): 80 B-trim: 338 in 1/51 Lambda= 0.080692 statistics sampled from 12505 (12575) to 12505 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.386), width: 16 Scan time: 4.240 The best scores are: opt bits E(32554) CCDS8218.2 FCHSD2 gene_id:9873|Hs108|chr11 ( 740) 4511 538.8 1.1e-152 CCDS47295.1 FCHSD1 gene_id:89848|Hs108|chr5 ( 690) 1021 132.5 2.1e-30 >>CCDS8218.2 FCHSD2 gene_id:9873|Hs108|chr11 (740 aa) initn: 4511 init1: 4511 opt: 4511 Z-score: 2854.8 bits: 538.8 E(32554): 1.1e-152 Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 684 aa overlap (1-684:57-740) 10 20 30 pF1KSD MQKLASQYLKRDWPGVKADDRNDYRSMYPV :::::::::::::::::::::::::::::: CCDS82 AKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKLASQYLKRDWPGVKADDRNDYRSMYPV 30 40 50 60 70 80 40 50 60 70 80 90 pF1KSD WKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 WKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVK 90 100 110 120 130 140 100 110 120 130 140 150 pF1KSD DLAKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNSKATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 DLAKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNSKATH 150 160 170 180 190 200 160 170 180 190 200 210 pF1KSD ARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNT 210 220 230 240 250 260 220 230 240 250 260 270 pF1KSD FQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 FQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNK 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD EARKWATRVAREHKNIVHQQRVLNDLECHGAAVSEQSRAELEQKIDEARENIRKAEIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EARKWATRVAREHKNIVHQQRVLNDLECHGAAVSEQSRAELEQKIDEARENIRKAEIIKL 330 340 350 360 370 380 340 350 360 370 380 390 pF1KSD KAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADTEREEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADTEREEG 390 400 410 420 430 440 400 410 420 430 440 450 pF1KSD EEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMED 450 460 470 480 490 500 460 470 480 490 500 510 pF1KSD WVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 WVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGD 510 520 530 540 550 560 520 530 540 550 560 570 pF1KSD ASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFPSVLVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFPSVLVEE 570 580 590 600 610 620 580 590 600 610 620 630 pF1KSD LSASENGDTPWMREIQISPSPKPHASLPPLPLYDQPPSSPYPSPDKRSSLYFPRSPSANE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LSASENGDTPWMREIQISPSPKPHASLPPLPLYDQPPSSPYPSPDKRSSLYFPRSPSANE 630 640 650 660 670 680 640 650 660 670 680 pF1KSD KSLHAESPGFSQASRHTPETSYGKLRPVRAAPPPPTQNHRRPAEKIEDVEITLV :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KSLHAESPGFSQASRHTPETSYGKLRPVRAAPPPPTQNHRRPAEKIEDVEITLV 690 700 710 720 730 740 >>CCDS47295.1 FCHSD1 gene_id:89848|Hs108|chr5 (690 aa) initn: 1070 init1: 337 opt: 1021 Z-score: 659.5 bits: 132.5 E(32554): 2.1e-30 Smith-Waterman score: 1334; 38.0% identity (66.3% similar) in 677 aa overlap (1-667:57-679) 10 20 pF1KSD MQKLASQYLKRDWPGVKADDRNDY-RSMYP .::::. .:::. : .. . .. :... CCDS47 TWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKRE--GHRSGEMDSRGRTVFG 30 40 50 60 70 80 30 40 50 60 70 80 pF1KSD VWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETV .:. .:..:. .:.:.. . :... . : :: ::: :.. ...: . :.:. ..: CCDS47 AWRCLLDATVAGGQTRLQASDRYRDLA---GGTGRSAKEQVLRKGTENLQRAQAEVLQSV 90 100 110 120 130 140 90 100 110 120 130 140 pF1KSD KDLAKGKKKYFETEQMAHAVREKA-DIEAK---SKLSLFQSRISLQKASVKLKARRSECN ..:....: : . :.. ..::: :..:. : ..:.:: :::: :.::.:. .. . CCDS47 RELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYS 150 160 170 180 190 200 150 160 170 180 190 200 pF1KSD SKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQ .. :::.:::.:.:.::: :.::: .: ..::: ... .::.: : ..:.::::. . CCDS47 QQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTELEAAE 210 220 230 240 250 260 210 220 230 240 250 260 pF1KSD AVQNTFQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLE-SETGTTE .. . . ...:.: . .:.::::: .:: : :::: .: :: . :.. CCDS47 VILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCVLEWGAEGVAG 270 280 290 300 310 320 270 280 290 300 310 320 pF1KSD EHSLNKEARKWATRVAREHKNIVHQQRVLNDLECHGAAVSEQSRAELEQKIDEARENIRK . .:.::... ..:.::..: : .:::. :: . .::. .::...:.::.::. CCDS47 KSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQASEREAPSIEQRLQEVRESIRR 330 340 350 360 370 380 330 340 350 360 370 380 pF1KSD AEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNAD :.. ..:. ::: ::. :..:. ::: ::.:...:.:.:: : :. : : CCDS47 AQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVEQERRLSE-ARLSQRDLSPTAED 390 400 410 420 430 440 390 400 410 420 430 440 pF1KSD TEREEGEEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIE .: . :: :.. ..:.. . . .: : : .::. :.:.. ::::: : : ::::: CCDS47 AELSDFEECEETGELFEEPAPQALAT-RALPCPAHVVFRYQAGREDELTITEGEWLEVIE 450 460 470 480 490 450 460 470 480 490 500 pF1KSD DGDMEDWVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVS .:: ..::::::. :.::.:::.::.:: ::. .: :. :.: :: CCDS47 EGDADEWVKARNQHGEVGFVPERYLNFPD----LSLPES-------SQDSDNPCGAE--- 500 510 520 530 540 510 520 530 540 550 560 pF1KSD GSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQD--DDGFWEGEFNGRIGV .. ...:::.: ::. .::::::::.::.: . :: :::::.:::.::.:: CCDS47 ------PTAFLAQALYSYTGQSAEELSFPEGALIRLLPRA-QDGVDDGFWRGEFGGRVGV 550 560 570 580 590 570 580 590 600 610 620 pF1KSD FPSVLVEELSASENGDTPWMREIQISPSPKPHASLPPLP--LYDQPPSSPYPSPDKRSSL :::.::::: . : :. :::.: . :: : . : ::. :. :: .: CCDS47 FPSLLVEEL-LGPPGPPELSDPEQMLPSPSPPSFSPPAPTSVLDGPPAPVLPG-DK--AL 600 610 620 630 640 650 630 640 650 660 670 680 pF1KSD YFPRSPSANEKSLHAESPGFSQASRHTPETSYGKLRPVRAAPPPPTQNHRRPAEKIEDVE :: :: . .: .:::.: ::::.. CCDS47 DFP---------------GFLDM--MAP-----RLRPMRPPPPPPAKAPDPGHPDPLT 660 670 680 690 pF1KSD ITLV 684 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:01:58 2016 done: Thu Nov 3 03:01:59 2016 Total Scan time: 4.240 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]