FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0827, 1531 aa 1>>>pF1KSDA0827 1531 - 1531 aa - 1531 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.9869+/-0.000533; mu= -13.2460+/- 0.033 mean_var=478.8136+/-103.256, 0's: 0 Z-trim(118.4): 305 B-trim: 556 in 1/58 Lambda= 0.058613 statistics sampled from 31007 (31313) to 31007 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.367), width: 16 Scan time: 21.550 The best scores are: opt bits E(85289) NP_006590 (OMIM: 604708) nuclear factor of activat (1531) 10007 862.7 0 XP_011521119 (OMIM: 604708) PREDICTED: nuclear fac (1530) 9990 861.3 0 NP_619727 (OMIM: 604708) nuclear factor of activat (1549) 9858 850.1 0 NP_001106649 (OMIM: 604708) nuclear factor of acti (1548) 9841 848.7 0 XP_006721188 (OMIM: 604708) PREDICTED: nuclear fac (1484) 9712 837.7 0 NP_775321 (OMIM: 604708) nuclear factor of activat (1455) 9530 822.3 0 NP_775322 (OMIM: 604708) nuclear factor of activat (1455) 9530 822.3 0 NP_619728 (OMIM: 604708) nuclear factor of activat (1455) 9530 822.3 0 XP_011521120 (OMIM: 604708) PREDICTED: nuclear fac (1455) 9530 822.3 0 XP_016878359 (OMIM: 604708) PREDICTED: nuclear fac (1455) 9530 822.3 0 XP_016878360 (OMIM: 604708) PREDICTED: nuclear fac (1454) 9513 820.9 0 XP_011521121 (OMIM: 604708) PREDICTED: nuclear fac (1325) 8349 722.4 5.7e-207 XP_011521124 (OMIM: 604708) PREDICTED: nuclear fac (1325) 8349 722.4 5.7e-207 XP_016878361 (OMIM: 604708) PREDICTED: nuclear fac (1325) 8349 722.4 5.7e-207 XP_011521122 (OMIM: 604708) PREDICTED: nuclear fac (1325) 8349 722.4 5.7e-207 XP_016878362 (OMIM: 604708) PREDICTED: nuclear fac (1324) 8332 721.0 1.6e-206 XP_016883339 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 804 84.2 4.1e-15 XP_011527128 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 804 84.2 4.1e-15 XP_011527127 (OMIM: 600490) PREDICTED: nuclear fac ( 920) 804 84.3 5e-15 XP_011527126 (OMIM: 600490) PREDICTED: nuclear fac ( 940) 804 84.3 5.1e-15 NP_001245225 (OMIM: 600490) nuclear factor of acti ( 702) 785 82.6 1.2e-14 NP_001245223 (OMIM: 600490) nuclear factor of acti ( 702) 785 82.6 1.2e-14 NP_001245224 (OMIM: 600490) nuclear factor of acti ( 706) 785 82.6 1.2e-14 NP_001245226 (OMIM: 600490) nuclear factor of acti ( 706) 785 82.6 1.2e-14 NP_001129493 (OMIM: 600490) nuclear factor of acti ( 901) 785 82.7 1.5e-14 NP_001245221 (OMIM: 600490) nuclear factor of acti ( 905) 785 82.7 1.5e-14 NP_036472 (OMIM: 600490) nuclear factor of activat ( 921) 785 82.7 1.5e-14 NP_775114 (OMIM: 600490) nuclear factor of activat ( 925) 785 82.7 1.5e-14 NP_775186 (OMIM: 602698) nuclear factor of activat (1065) 780 82.3 2.3e-14 NP_004546 (OMIM: 602698) nuclear factor of activat (1068) 780 82.3 2.3e-14 NP_775188 (OMIM: 602698) nuclear factor of activat (1075) 780 82.3 2.3e-14 NP_001265604 (OMIM: 600489) nuclear factor of acti ( 703) 761 80.6 5.1e-14 NP_765978 (OMIM: 600489) nuclear factor of activat ( 716) 761 80.6 5.1e-14 XP_016883340 (OMIM: 600490) PREDICTED: nuclear fac ( 695) 759 80.4 5.6e-14 NP_001265601 (OMIM: 600489) nuclear factor of acti ( 700) 755 80.1 7.2e-14 NP_001265599 (OMIM: 600489) nuclear factor of acti ( 713) 755 80.1 7.3e-14 NP_765975 (OMIM: 600489) nuclear factor of activat ( 930) 756 80.3 8.4e-14 NP_001265598 (OMIM: 600489) nuclear factor of acti ( 943) 756 80.3 8.5e-14 NP_765977 (OMIM: 600489) nuclear factor of activat ( 812) 753 80.0 9e-14 NP_006153 (OMIM: 600489) nuclear factor of activat ( 825) 753 80.0 9.1e-14 XP_011535101 (OMIM: 602699) PREDICTED: nuclear fac ( 782) 682 73.9 5.6e-12 NP_001185894 (OMIM: 602699) nuclear factor of acti ( 794) 682 73.9 5.7e-12 NP_001185895 (OMIM: 602699) nuclear factor of acti ( 832) 682 74.0 5.9e-12 NP_001185896 (OMIM: 602699) nuclear factor of acti ( 857) 682 74.0 6e-12 XP_011535100 (OMIM: 602699) PREDICTED: nuclear fac ( 879) 682 74.0 6.1e-12 NP_001275731 (OMIM: 602699) nuclear factor of acti ( 889) 682 74.0 6.2e-12 XP_011535099 (OMIM: 602699) PREDICTED: nuclear fac ( 890) 682 74.0 6.2e-12 NP_004545 (OMIM: 602699) nuclear factor of activat ( 902) 682 74.0 6.3e-12 NP_001129494 (OMIM: 602699) nuclear factor of acti ( 964) 682 74.0 6.6e-12 NP_001306972 (OMIM: 602699) nuclear factor of acti ( 965) 682 74.0 6.6e-12 >>NP_006590 (OMIM: 604708) nuclear factor of activated T (1531 aa) initn: 10007 init1: 10007 opt: 10007 Z-score: 4593.5 bits: 862.7 E(85289): 0 Smith-Waterman score: 10007; 100.0% identity (100.0% similar) in 1531 aa overlap (1-1531:1-1531) 10 20 30 40 50 60 pF1KSD MPSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MPSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD YTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD MIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSRE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD VSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD QQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD VSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD VNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIAD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD AQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD FLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD QQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD EQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPAS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD MSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD QQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KSD LASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::: NP_006 LASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1510 1520 1530 >>XP_011521119 (OMIM: 604708) PREDICTED: nuclear factor (1530 aa) initn: 6397 init1: 6397 opt: 9990 Z-score: 4585.8 bits: 861.3 E(85289): 0 Smith-Waterman score: 9990; 99.9% identity (99.9% similar) in 1531 aa overlap (1-1531:1-1530) 10 20 30 40 50 60 pF1KSD MPSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD YTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSS ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTPDPAA-GALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSS 550 560 570 580 590 610 620 630 640 650 660 pF1KSD MIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD KQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSRE 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD ILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQA 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD GSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSG 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD VSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEM 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD QQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPA 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD VSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD VNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIAD 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KSD AQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNI 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KSD FLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KSD AQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQ 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD QQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQ 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD EQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPAS 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KSD MSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSS 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KSD QQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSP 1440 1450 1460 1470 1480 1490 1510 1520 1530 pF1KSD LASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::: XP_011 LASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1500 1510 1520 1530 >>NP_619727 (OMIM: 604708) nuclear factor of activated T (1549 aa) initn: 9856 init1: 9856 opt: 9858 Z-score: 4525.4 bits: 850.1 E(85289): 0 Smith-Waterman score: 9961; 98.8% identity (98.8% similar) in 1549 aa overlap (1-1531:1-1549) 10 20 30 40 pF1KSD MPSDFISLLSADLDLESPKSLYSR------------------ESVYDLLPKELQLPPSRE :::::::::::::::::::::::: :::::::::::::::::: NP_619 MPSDFISLLSADLDLESPKSLYSRDSLKLHPSQNFHRAGLLEESVYDLLPKELQLPPSRE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD TSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 TSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD MQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 MQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD GCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNM 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD DIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 DIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKEL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD KIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 KIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHG 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD FYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 FYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIA 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD GSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEE 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD VFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 VFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD GIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNL 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD DKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 DKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD GNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSD 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIF 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD PSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 PSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENV 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQ 850 860 870 880 890 900 890 900 910 920 930 940 pF1KSD QQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSAL 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KSD STNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 STNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KSD SVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQ 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KSD QSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQST 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KSD IAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 IAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAF 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KSD QQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQ 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KSD SNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQE 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KSD QQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQ 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KSD GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLF 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KSD HNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 HNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 pF1KSD GQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1510 1520 1530 1540 >>NP_001106649 (OMIM: 604708) nuclear factor of activate (1548 aa) initn: 6548 init1: 6397 opt: 9841 Z-score: 4517.6 bits: 848.7 E(85289): 0 Smith-Waterman score: 9944; 98.8% identity (98.8% similar) in 1549 aa overlap (1-1531:1-1548) 10 20 30 40 pF1KSD MPSDFISLLSADLDLESPKSLYSR------------------ESVYDLLPKELQLPPSRE :::::::::::::::::::::::: :::::::::::::::::: NP_001 MPSDFISLLSADLDLESPKSLYSRDSLKLHPSQNFHRAGLLEESVYDLLPKELQLPPSRE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD TSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD MQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD GCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNM 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD DIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKEL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD KIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHG 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD FYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIA 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD GSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEE 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD VFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD GIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNL ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: NP_001 GIYVVTNAGRSHDVQPFTYTPDPAA-GALNVNVKKEISSPARPCSFEEAMKAMKTTGCNL 550 560 570 580 590 590 600 610 620 630 640 pF1KSD DKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA 600 610 620 630 640 650 650 660 670 680 690 700 pF1KSD GNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSD 660 670 680 690 700 710 710 720 730 740 750 760 pF1KSD ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIF 720 730 740 750 760 770 770 780 790 800 810 820 pF1KSD PSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENV 780 790 800 810 820 830 830 840 850 860 870 880 pF1KSD QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQ 840 850 860 870 880 890 890 900 910 920 930 940 pF1KSD QQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSAL 900 910 920 930 940 950 950 960 970 980 990 1000 pF1KSD STNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQN 960 970 980 990 1000 1010 1010 1020 1030 1040 1050 1060 pF1KSD SVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQ 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 1110 1120 pF1KSD QSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQST 1080 1090 1100 1110 1120 1130 1130 1140 1150 1160 1170 1180 pF1KSD IAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAF 1140 1150 1160 1170 1180 1190 1190 1200 1210 1220 1230 1240 pF1KSD QQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQ 1200 1210 1220 1230 1240 1250 1250 1260 1270 1280 1290 1300 pF1KSD SNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQE 1260 1270 1280 1290 1300 1310 1310 1320 1330 1340 1350 1360 pF1KSD QQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQ 1320 1330 1340 1350 1360 1370 1370 1380 1390 1400 1410 1420 pF1KSD GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLF 1380 1390 1400 1410 1420 1430 1430 1440 1450 1460 1470 1480 pF1KSD HNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE 1440 1450 1460 1470 1480 1490 1490 1500 1510 1520 1530 pF1KSD GQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1500 1510 1520 1530 1540 >>XP_006721188 (OMIM: 604708) PREDICTED: nuclear factor (1484 aa) initn: 9712 init1: 9712 opt: 9712 Z-score: 4458.9 bits: 837.7 E(85289): 0 Smith-Waterman score: 9712; 100.0% identity (100.0% similar) in 1484 aa overlap (48-1531:1-1484) 20 30 40 50 60 70 pF1KSD PKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSM :::::::::::::::::::::::::::::: XP_006 MSQTSGGEAGSPPPAVVAADASSAPSSSSM 10 20 30 80 90 100 110 120 130 pF1KSD GGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPK 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD RHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEV 100 110 120 130 140 150 200 210 220 230 240 250 pF1KSD PRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLEN 160 170 180 190 200 210 260 270 280 290 300 310 pF1KSD QKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVK 220 230 240 250 260 270 320 330 340 350 360 370 pF1KSD LEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNN 280 290 300 310 320 330 380 390 400 410 420 430 pF1KSD MTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPIL 340 350 360 370 380 390 440 450 460 470 480 490 pF1KSD CTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDME 400 410 420 430 440 450 500 510 520 530 540 550 pF1KSD LFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKK 460 470 480 490 500 510 560 570 580 590 600 610 pF1KSD EISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKR 520 530 540 550 560 570 620 630 640 650 660 670 pF1KSD SSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTT 580 590 600 610 620 630 680 690 700 710 720 730 pF1KSD IQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEA 640 650 660 670 680 690 740 750 760 770 780 790 pF1KSD SQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDL 700 710 720 730 740 750 800 810 820 830 840 850 pF1KSD VQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRP 760 770 780 790 800 810 860 870 880 890 900 910 pF1KSD DNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFP 820 830 840 850 860 870 920 930 940 950 960 970 pF1KSD STASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 880 890 900 910 920 930 980 990 1000 1010 1020 1030 pF1KSD GTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSG 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 pF1KSD TQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPN 1000 1010 1020 1030 1040 1050 1100 1110 1120 1130 1140 1150 pF1KSD PIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQ 1060 1070 1080 1090 1100 1110 1160 1170 1180 1190 1200 1210 pF1KSD EAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGS 1120 1130 1140 1150 1160 1170 1220 1230 1240 1250 1260 1270 pF1KSD LPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1180 1190 1200 1210 1220 1230 1280 1290 1300 1310 1320 1330 pF1KSD TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1240 1250 1260 1270 1280 1290 1340 1350 1360 1370 1380 1390 pF1KSD NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KSD LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQ 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KSD LLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLL 1420 1430 1440 1450 1460 1470 1520 1530 pF1KSD VSLQNQGNNLTGSF :::::::::::::: XP_006 VSLQNQGNNLTGSF 1480 >>NP_775321 (OMIM: 604708) nuclear factor of activated T (1455 aa) initn: 9530 init1: 9530 opt: 9530 Z-score: 4375.9 bits: 822.3 E(85289): 0 Smith-Waterman score: 9530; 100.0% identity (100.0% similar) in 1455 aa overlap (77-1531:1-1455) 50 60 70 80 90 100 pF1KSD SMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVE :::::::::::::::::::::::::::::: NP_775 MGGACSSFTTSSSPTIYSTSVTDSKAMQVE 10 20 30 110 120 130 140 150 160 pF1KSD SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KSD VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KSD IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KSD FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ 580 590 600 610 620 630 710 720 730 740 750 760 pF1KSD QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN 640 650 660 670 680 690 770 780 790 800 810 820 pF1KSD SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KSD SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ 760 770 780 790 800 810 890 900 910 920 930 940 pF1KSD QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KSD DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KSD TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KSD SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KSD QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KSD PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KSD SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KSD SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KSD SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KSD GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KSD VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::: NP_775 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1420 1430 1440 1450 >>NP_775322 (OMIM: 604708) nuclear factor of activated T (1455 aa) initn: 9530 init1: 9530 opt: 9530 Z-score: 4375.9 bits: 822.3 E(85289): 0 Smith-Waterman score: 9530; 100.0% identity (100.0% similar) in 1455 aa overlap (77-1531:1-1455) 50 60 70 80 90 100 pF1KSD SMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVE :::::::::::::::::::::::::::::: NP_775 MGGACSSFTTSSSPTIYSTSVTDSKAMQVE 10 20 30 110 120 130 140 150 160 pF1KSD SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KSD VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KSD IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KSD FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ 580 590 600 610 620 630 710 720 730 740 750 760 pF1KSD QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN 640 650 660 670 680 690 770 780 790 800 810 820 pF1KSD SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KSD SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ 760 770 780 790 800 810 890 900 910 920 930 940 pF1KSD QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KSD DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KSD TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KSD SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KSD QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KSD PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KSD SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KSD SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KSD SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KSD GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KSD VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::: NP_775 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1420 1430 1440 1450 >>NP_619728 (OMIM: 604708) nuclear factor of activated T (1455 aa) initn: 9530 init1: 9530 opt: 9530 Z-score: 4375.9 bits: 822.3 E(85289): 0 Smith-Waterman score: 9530; 100.0% identity (100.0% similar) in 1455 aa overlap (77-1531:1-1455) 50 60 70 80 90 100 pF1KSD SMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVE :::::::::::::::::::::::::::::: NP_619 MGGACSSFTTSSSPTIYSTSVTDSKAMQVE 10 20 30 110 120 130 140 150 160 pF1KSD SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KSD VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KSD IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KSD FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ 580 590 600 610 620 630 710 720 730 740 750 760 pF1KSD QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN 640 650 660 670 680 690 770 780 790 800 810 820 pF1KSD SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KSD SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ 760 770 780 790 800 810 890 900 910 920 930 940 pF1KSD QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KSD DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KSD TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KSD SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KSD QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KSD PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KSD SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KSD SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KSD SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KSD GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_619 GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KSD VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::: NP_619 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1420 1430 1440 1450 >>XP_011521120 (OMIM: 604708) PREDICTED: nuclear factor (1455 aa) initn: 9530 init1: 9530 opt: 9530 Z-score: 4375.9 bits: 822.3 E(85289): 0 Smith-Waterman score: 9530; 100.0% identity (100.0% similar) in 1455 aa overlap (77-1531:1-1455) 50 60 70 80 90 100 pF1KSD SMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVE :::::::::::::::::::::::::::::: XP_011 MGGACSSFTTSSSPTIYSTSVTDSKAMQVE 10 20 30 110 120 130 140 150 160 pF1KSD SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KSD VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KSD IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KSD FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ 580 590 600 610 620 630 710 720 730 740 750 760 pF1KSD QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN 640 650 660 670 680 690 770 780 790 800 810 820 pF1KSD SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KSD SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ 760 770 780 790 800 810 890 900 910 920 930 940 pF1KSD QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KSD DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KSD TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KSD SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KSD QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KSD PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KSD SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KSD SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KSD SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KSD GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KSD VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1420 1430 1440 1450 >>XP_016878359 (OMIM: 604708) PREDICTED: nuclear factor (1455 aa) initn: 9530 init1: 9530 opt: 9530 Z-score: 4375.9 bits: 822.3 E(85289): 0 Smith-Waterman score: 9530; 100.0% identity (100.0% similar) in 1455 aa overlap (77-1531:1-1455) 50 60 70 80 90 100 pF1KSD SMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVE :::::::::::::::::::::::::::::: XP_016 MGGACSSFTTSSSPTIYSTSVTDSKAMQVE 10 20 30 110 120 130 140 150 160 pF1KSD SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKK 280 290 300 310 320 330 410 420 430 440 450 460 pF1KSD KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KSD GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KSD VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVN 460 470 480 490 500 510 590 600 610 620 630 640 pF1KSD IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KSD FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQ 580 590 600 610 620 630 710 720 730 740 750 760 pF1KSD QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPN 640 650 660 670 680 690 770 780 790 800 810 820 pF1KSD SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQL 700 710 720 730 740 750 830 840 850 860 870 880 pF1KSD SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQ 760 770 780 790 800 810 890 900 910 920 930 940 pF1KSD QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNE 820 830 840 850 860 870 950 960 970 980 990 1000 pF1KSD DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQ 880 890 900 910 920 930 1010 1020 1030 1040 1050 1060 pF1KSD TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSH 940 950 960 970 980 990 1070 1080 1090 1100 1110 1120 pF1KSD SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVL 1000 1010 1020 1030 1040 1050 1130 1140 1150 1160 1170 1180 pF1KSD QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQA 1060 1070 1080 1090 1100 1110 1190 1200 1210 1220 1230 1240 pF1KSD PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSP 1120 1130 1140 1150 1160 1170 1250 1260 1270 1280 1290 1300 pF1KSD SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1180 1190 1200 1210 1220 1230 1310 1320 1330 1340 1350 1360 pF1KSD SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPS 1240 1250 1260 1270 1280 1290 1370 1380 1390 1400 1410 1420 pF1KSD SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTA 1300 1310 1320 1330 1340 1350 1430 1440 1450 1460 1470 1480 pF1KSD GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPP 1360 1370 1380 1390 1400 1410 1490 1500 1510 1520 1530 pF1KSD VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF ::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1420 1430 1440 1450 1531 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:45:03 2016 done: Thu Nov 3 18:45:07 2016 Total Scan time: 21.550 Total Display time: 1.160 Function used was FASTA [36.3.4 Apr, 2011]