Result of FASTA (omim) for
pF1KSDA0828
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0828, 610 aa
1>>>pF1KSDA0828 610 - 610 aa - 610 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0246+/-0.000387; mu= -1.0881+/- 0.024
mean_var=235.1254+/-47.963, 0's: 0 Z-trim(120.0): 31 B-trim: 1941 in 1/55
Lambda= 0.083642
statistics sampled from 34668 (34700) to 34668 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.407), width: 16
Scan time: 11.440
The best scores are: opt bits E(85289)
NP_001124192 (OMIM: 616520) adenosylhomocysteinase ( 610) 4095 507.2 6.8e-143
NP_056143 (OMIM: 616520) adenosylhomocysteinase 3 ( 611) 4083 505.7 1.9e-142
NP_001124194 (OMIM: 616520) adenosylhomocysteinase ( 508) 3296 410.7 6.2e-114
XP_005250294 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3296 410.7 6.2e-114
XP_011514289 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3296 410.7 6.2e-114
XP_011514290 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3296 410.7 6.2e-114
NP_001124195 (OMIM: 616520) adenosylhomocysteinase ( 508) 3294 410.5 7.3e-114
NP_006612 (OMIM: 607826) adenosylhomocysteinase 2 ( 530) 3123 389.8 1.2e-107
NP_001229602 (OMIM: 607826) adenosylhomocysteinase ( 483) 3064 382.7 1.6e-105
NP_001229605 (OMIM: 607826) adenosylhomocysteinase ( 483) 3064 382.7 1.6e-105
NP_001229603 (OMIM: 607826) adenosylhomocysteinase ( 483) 3064 382.7 1.6e-105
NP_001229604 (OMIM: 607826) adenosylhomocysteinase ( 483) 3064 382.7 1.6e-105
XP_011538837 (OMIM: 607826) PREDICTED: adenosylhom ( 505) 2852 357.1 8.3e-98
XP_016867396 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2752 345.0 2.9e-94
XP_016867393 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2752 345.0 2.9e-94
XP_016867395 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2752 345.0 2.9e-94
XP_016867394 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2752 345.0 2.9e-94
XP_011526960 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1484 192.0 3.6e-48
XP_011526959 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1484 192.0 3.6e-48
NP_001309015 (OMIM: 180960,613752) adenosylhomocys ( 434) 1484 192.0 3.6e-48
XP_011526958 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1484 192.0 3.6e-48
XP_016883197 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1479 191.4 5.4e-48
XP_016883198 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1479 191.4 5.4e-48
NP_000678 (OMIM: 180960,613752) adenosylhomocystei ( 432) 1479 191.4 5.4e-48
XP_005260374 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1423 184.6 5.6e-46
NP_001155238 (OMIM: 180960,613752) adenosylhomocys ( 404) 1423 184.6 5.6e-46
NP_001309013 (OMIM: 180960,613752) adenosylhomocys ( 404) 1423 184.6 5.6e-46
XP_011526961 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1423 184.6 5.6e-46
NP_001309014 (OMIM: 180960,613752) adenosylhomocys ( 404) 1423 184.6 5.6e-46
XP_016883199 (OMIM: 180960,613752) PREDICTED: aden ( 306) 1058 140.5 8e-33
>>NP_001124192 (OMIM: 616520) adenosylhomocysteinase 3 i (610 aa)
initn: 4095 init1: 4095 opt: 4095 Z-score: 2686.4 bits: 507.2 E(85289): 6.8e-143
Smith-Waterman score: 4095; 100.0% identity (100.0% similar) in 610 aa overlap (1-610:1-610)
10 20 30 40 50 60
pF1KSD MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD WQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD TQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKN
550 560 570 580 590 600
610
pF1KSD GPFKPNYYRY
::::::::::
NP_001 GPFKPNYYRY
610
>>NP_056143 (OMIM: 616520) adenosylhomocysteinase 3 isof (611 aa)
initn: 3302 init1: 3302 opt: 4083 Z-score: 2678.5 bits: 505.7 E(85289): 1.9e-142
Smith-Waterman score: 4083; 99.8% identity (99.8% similar) in 611 aa overlap (1-610:1-611)
10 20 30 40 50 60
pF1KSD MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
70 80 90 100 110 120
130 140 150 160 170
pF1KSD K-IQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNS
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD KGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD VLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD GWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD DSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD TEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGH
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD SNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD TTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNK
550 560 570 580 590 600
600 610
pF1KSD NGPFKPNYYRY
:::::::::::
NP_056 NGPFKPNYYRY
610
>>NP_001124194 (OMIM: 616520) adenosylhomocysteinase 3 i (508 aa)
initn: 3296 init1: 3296 opt: 3296 Z-score: 2166.5 bits: 410.7 E(85289): 6.2e-114
Smith-Waterman score: 3296; 99.8% identity (100.0% similar) in 490 aa overlap (121-610:19-508)
100 110 120 130 140 150
pF1KSD PHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQS
.:::::::::::::::::::::::::::::
NP_001 MLGSKKKYIVNGNSGIKAQIQFADQKQEFNKRPTKIGRRSLSRSISQS
10 20 30 40
160 170 180 190 200 210
pF1KSD STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
410 420 430 440 450 460
580 590 600 610
pF1KSD YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::::::::::::::::::::::::
NP_001 YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
>>XP_005250294 (OMIM: 616520) PREDICTED: adenosylhomocys (509 aa)
initn: 3296 init1: 3296 opt: 3296 Z-score: 2166.5 bits: 410.7 E(85289): 6.2e-114
Smith-Waterman score: 3296; 99.8% identity (100.0% similar) in 490 aa overlap (121-610:20-509)
100 110 120 130 140 150
pF1KSD PHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQS
.:::::::::::::::::::::::::::::
XP_005 MEKWDGNEGTSAFHMPEWMQIQFADQKQEFNKRPTKIGRRSLSRSISQS
10 20 30 40
160 170 180 190 200 210
pF1KSD STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
410 420 430 440 450 460
580 590 600 610
pF1KSD YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::::::::::::::::::::::::
XP_005 YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
>>XP_011514289 (OMIM: 616520) PREDICTED: adenosylhomocys (509 aa)
initn: 3296 init1: 3296 opt: 3296 Z-score: 2166.5 bits: 410.7 E(85289): 6.2e-114
Smith-Waterman score: 3296; 99.8% identity (100.0% similar) in 490 aa overlap (121-610:20-509)
100 110 120 130 140 150
pF1KSD PHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQS
.:::::::::::::::::::::::::::::
XP_011 MEKWDGNEGTSAFHMPEWMQIQFADQKQEFNKRPTKIGRRSLSRSISQS
10 20 30 40
160 170 180 190 200 210
pF1KSD STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
410 420 430 440 450 460
580 590 600 610
pF1KSD YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::::::::::::::::::::::::
XP_011 YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
>>XP_011514290 (OMIM: 616520) PREDICTED: adenosylhomocys (509 aa)
initn: 3296 init1: 3296 opt: 3296 Z-score: 2166.5 bits: 410.7 E(85289): 6.2e-114
Smith-Waterman score: 3296; 99.8% identity (100.0% similar) in 490 aa overlap (121-610:20-509)
100 110 120 130 140 150
pF1KSD PHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQS
.:::::::::::::::::::::::::::::
XP_011 MEKWDGNEGTSAFHMPEWMQIQFADQKQEFNKRPTKIGRRSLSRSISQS
10 20 30 40
160 170 180 190 200 210
pF1KSD STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPAL
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAAL
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKG
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFG
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIV
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDE
410 420 430 440 450 460
580 590 600 610
pF1KSD YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::::::::::::::::::::::::
XP_011 YVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
>>NP_001124195 (OMIM: 616520) adenosylhomocysteinase 3 i (508 aa)
initn: 3294 init1: 3294 opt: 3294 Z-score: 2165.2 bits: 410.5 E(85289): 7.3e-114
Smith-Waterman score: 3294; 100.0% identity (100.0% similar) in 489 aa overlap (122-610:20-508)
100 110 120 130 140 150
pF1KSD HHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQSS
::::::::::::::::::::::::::::::
NP_001 MEKWDGNEGTSAFHMPEWMIQFADQKQEFNKRPTKIGRRSLSRSISQSS
10 20 30 40
160 170 180 190 200 210
pF1KSD TDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALM
50 60 70 80 90 100
220 230 240 250 260 270
pF1KSD ALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALA
110 120 130 140 150 160
280 290 300 310 320 330
pF1KSD ESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGI
170 180 190 200 210 220
340 350 360 370 380 390
pF1KSD VEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGG
230 240 250 260 270 280
400 410 420 430 440 450
pF1KSD KQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVI
290 300 310 320 330 340
460 470 480 490 500 510
pF1KSD TCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDG
350 360 370 380 390 400
520 530 540 550 560 570
pF1KSD KRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEY
410 420 430 440 450 460
580 590 600 610
pF1KSD VASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::::::::::::::::::::::
NP_001 VASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
>>NP_006612 (OMIM: 607826) adenosylhomocysteinase 2 isof (530 aa)
initn: 3103 init1: 3103 opt: 3123 Z-score: 2053.4 bits: 389.8 E(85289): 1.2e-107
Smith-Waterman score: 3123; 91.8% identity (97.6% similar) in 500 aa overlap (111-610:33-530)
90 100 110 120 130 140
pF1KSD PQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGR
:::.::. :.:::::. :::.: ::: ::
NP_006 MPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPK--KQIQFADDMQEFTKFPTKTGR
10 20 30 40 50 60
150 160 170 180 190 200
pF1KSD RSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREI
::::::::::::::::::::::::::::.:::.::: ::::::.::::::::::::::::
NP_006 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
70 80 90 100 110 120
210 220 230 240 250 260
pF1KSD EIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIY
:::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.:::::
NP_006 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
130 140 150 160 170 180
270 280 290 300 310 320
pF1KSD STLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKK
:: :::::::::.: :::::::::::::::::::::..::: :::::::::::::.:::
NP_006 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
190 200 210 220 230 240
330 340 350 360 370 380
pF1KSD YPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
:::.::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
250 260 270 280 290 300
390 400 410 420 430 440
pF1KSD LKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKL
::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.:::
NP_006 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
310 320 330 340 350 360
450 460 470 480 490 500
pF1KSD NEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVR
::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_006 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
370 380 390 400 410 420
510 520 530 540 550 560
pF1KSD SQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
430 440 450 460 470 480
570 580 590 600 610
pF1KSD VYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_006 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
490 500 510 520 530
>>NP_001229602 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3064 init1: 3064 opt: 3064 Z-score: 2015.5 bits: 382.7 E(85289): 1.6e-105
Smith-Waterman score: 3064; 92.9% identity (98.1% similar) in 482 aa overlap (129-610:2-483)
100 110 120 130 140 150
pF1KSD RDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSA
:::.: ::: ::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSSA
10 20 30
160 170 180 190 200 210
pF1KSD ASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQ
::::::::::.:::.::: ::::::.:::::::::::::::::::::.: ::..::::::
NP_001 ASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD GEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVF
:::::::::::::::::::::::.::: ::::::::.::::::: :::::::::.: ::
NP_001 GEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD AWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTG
:::::::::::::::::::..::: :::::::::::::.::::::.::::.:::::::::
NP_001 AWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD VHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCG
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_001 VHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCG
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD YGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKN
::::::::::::::.:.:::.:::::::::::::::::.:::::::::::.:::::::::
NP_001 YGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKN
280 290 300 310 320 330
460 470 480 490 500 510
pF1KSD VVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLA
::::::::::::::::::::::::::::.::::::::::::::::::::::::::.::::
NP_001 VVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLA
340 350 360 370 380 390
520 530 540 550 560 570
pF1KSD EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLP
400 410 420 430 440 450
580 590 600 610
pF1KSD TFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
.::::::::::.::::::::::::::::::::
NP_001 SFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
>>NP_001229605 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3064 init1: 3064 opt: 3064 Z-score: 2015.5 bits: 382.7 E(85289): 1.6e-105
Smith-Waterman score: 3064; 92.9% identity (98.1% similar) in 482 aa overlap (129-610:2-483)
100 110 120 130 140 150
pF1KSD RDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSA
:::.: ::: ::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSSA
10 20 30
160 170 180 190 200 210
pF1KSD ASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQ
::::::::::.:::.::: ::::::.:::::::::::::::::::::.: ::..::::::
NP_001 ASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD GEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVF
:::::::::::::::::::::::.::: ::::::::.::::::: :::::::::.: ::
NP_001 GEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD AWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTG
:::::::::::::::::::..::: :::::::::::::.::::::.::::.:::::::::
NP_001 AWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD VHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCG
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_001 VHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCG
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD YGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKN
::::::::::::::.:.:::.:::::::::::::::::.:::::::::::.:::::::::
NP_001 YGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKN
280 290 300 310 320 330
460 470 480 490 500 510
pF1KSD VVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLA
::::::::::::::::::::::::::::.::::::::::::::::::::::::::.::::
NP_001 VVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLA
340 350 360 370 380 390
520 530 540 550 560 570
pF1KSD EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLP
400 410 420 430 440 450
580 590 600 610
pF1KSD TFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
.::::::::::.::::::::::::::::::::
NP_001 SFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
610 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:36:10 2016 done: Thu Nov 3 03:36:11 2016
Total Scan time: 11.440 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]