FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0839, 1393 aa 1>>>pF1KSDA0839 1393 - 1393 aa - 1393 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5106+/-0.000448; mu= 22.3585+/- 0.028 mean_var=75.8512+/-15.026, 0's: 0 Z-trim(110.0): 6 B-trim: 259 in 2/52 Lambda= 0.147263 statistics sampled from 18238 (18242) to 18238 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.56), E-opt: 0.2 (0.214), width: 16 Scan time: 17.270 The best scores are: opt bits E(85289) NP_036546 (OMIM: 212720,609275,614225) rab3 GTPase (1393) 9243 1974.4 0 >>NP_036546 (OMIM: 212720,609275,614225) rab3 GTPase-act (1393 aa) initn: 9243 init1: 9243 opt: 9243 Z-score: 10603.4 bits: 1974.4 E(85289): 0 Smith-Waterman score: 9243; 100.0% identity (100.0% similar) in 1393 aa overlap (1-1393:1-1393) 10 20 30 40 50 60 pF1KSD MACSIVQFCYFQDLQAARDFLFPHLREEILSGALRRDPSKSTDWEDDGWGAWEENEPQEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MACSIVQFCYFQDLQAARDFLFPHLREEILSGALRRDPSKSTDWEDDGWGAWEENEPQEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVPKWKYSDKGKEEMQFAVGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EEEGNTCKTQKTSWLQDCVLSLSPTNDLMVIAREQKAVFLVPKWKYSDKGKEEMQFAVGW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SGSLNVEEGECVTSALCIPLASQKRSSTGRPDWTCIVVGFTSGYVRFYTENGVLLLAQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SGSLNVEEGECVTSALCIPLASQKRSSTGRPDWTCIVVGFTSGYVRFYTENGVLLLAQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NEDPVLQLKCRTYEIPRHPGVTEQNEELSILYPAAIVTIDGFSLFQSLRACRNQVAKAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NEDPVLQLKCRTYEIPRHPGVTEQNEELSILYPAAIVTIDGFSLFQSLRACRNQVAKAAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SGNENIQPPPLAYKKWGLQDIDTIIDHASVGIMTLSPFDQMKTASNIGGFNAAIKNSPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SGNENIQPPPLAYKKWGLQDIDTIIDHASVGIMTLSPFDQMKTASNIGGFNAAIKNSPPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MSQYITVGSNPFTGFFYALEGSTQPLLSHVALAVASKLTSALFNAASGWLGWKSKHEEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSQYITVGSNPFTGFFYALEGSTQPLLSHVALAVASKLTSALFNAASGWLGWKSKHEEEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD VQKQKPKVEPATPLAVRFGLPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VQKQKPKVEPATPLAVRFGLPDSRRHGESICLSPCNTLAAVTDDFGRVILLDVARGIAIR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD MWKGYRDAQIGWIQTVEDLHERVPEKADFSPFGNSQGPSRVAQFLVIYAPRRGILEVWST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MWKGYRDAQIGWIQTVEDLHERVPEKADFSPFGNSQGPSRVAQFLVIYAPRRGILEVWST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QQGPRVGAFNVGKHCRLLYPGYKIMGLNNVTSQSWQPQTYQICLVDPVSGSVKTVNVPFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QQGPRVGAFNVGKHCRLLYPGYKIMGLNNVTSQSWQPQTYQICLVDPVSGSVKTVNVPFH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD LALSDKKSERAKDMHLVKKLAALLKTKSPNLDLVETEIKELILDIKYPATKKQALESILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LALSDKKSERAKDMHLVKKLAALLKTKSPNLDLVETEIKELILDIKYPATKKQALESILA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SERLPFSCLRNITQTLMDTLKSQELESVDEGLLQFCANKLKLLQLYESVSQLNSLDFHLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SERLPFSCLRNITQTLMDTLKSQELESVDEGLLQFCANKLKLLQLYESVSQLNSLDFHLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD TPFSDNDLALLLRLDEKELLKLQALLEKYKQENTRTNVRFSDDKDGVLPVKTFLEYLEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TPFSDNDLALLLRLDEKELLKLQALLEKYKQENTRTNVRFSDDKDGVLPVKTFLEYLEYE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDVLNIKKISEEEYVALGSFFFWKCLHGESSTEDMCHTLESAGLSPQLLLSLLLSVWLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KDVLNIKKISEEEYVALGSFFFWKCLHGESSTEDMCHTLESAGLSPQLLLSLLLSVWLSK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD EKDILDKPQSICCLHTMLSLLSKMKVAIDETWDSQSVSPWWQQMRTACIQSENNGAALLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EKDILDKPQSICCLHTMLSLLSKMKVAIDETWDSQSVSPWWQQMRTACIQSENNGAALLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD AHVGHSVAAQISNNMTEKKFSQTVLGADSEALTDSWEALSLDTEYWKLLLKQLEDCLILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AHVGHSVAAQISNNMTEKKFSQTVLGADSEALTDSWEALSLDTEYWKLLLKQLEDCLILQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD TLLHSKGNTQTSKVSSLQAEPLPRLSVKKLLEGGKGGIADSVAKWIFKQDFSPEVLKLAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TLLHSKGNTQTSKVSSLQAEPLPRLSVKKLLEGGKGGIADSVAKWIFKQDFSPEVLKLAN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD EERDAENPDEPKEGVNRSFLEVSEMEMDLGAIPDLLHLAYEQFPCSLELDVLHAHCCWEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EERDAENPDEPKEGVNRSFLEVSEMEMDLGAIPDLLHLAYEQFPCSLELDVLHAHCCWEY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD VVQWNKDPEEARFFVRSIEHLKQIFNAHVQNGIALMMWNTFLVKRFSAATYLMDKVGKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VVQWNKDPEEARFFVRSIEHLKQIFNAHVQNGIALMMWNTFLVKRFSAATYLMDKVGKSP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD KDRLCRRDVGMSDTAMTSFLGSCLDLLQILMEADVSRDEIQVPVLDTEDAWLSVEGPISI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KDRLCRRDVGMSDTAMTSFLGSCLDLLQILMEADVSRDEIQVPVLDTEDAWLSVEGPISI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD VELALEQKHIHYPLVEHHSILCSILYAVMRFSLKTVKPLSLFDSKGKNAFFKDLTSIQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VELALEQKHIHYPLVEHHSILCSILYAVMRFSLKTVKPLSLFDSKGKNAFFKDLTSIQLL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD PSGEMDPNFISVRQQFLLKVVSAAVQAQHSATKVKDPTEEATPTPFGKDQDWPALAVDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PSGEMDPNFISVRQQFLLKVVSAAVQAQHSATKVKDPTEEATPTPFGKDQDWPALAVDLA 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD HHLQVSEDVVRRHYVGELYNYGVDHLGEEAILQVHDKEVLASQLLVLTGQRLAHALLHTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HHLQVSEDVVRRHYVGELYNYGVDHLGEEAILQVHDKEVLASQLLVLTGQRLAHALLHTQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD TKEGMELLARLPPTLCTWLKAMDPQDLQNTEVPIATTAKLVNKVIELLPEKHGQYGLALH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 TKEGMELLARLPPTLCTWLKAMDPQDLQNTEVPIATTAKLVNKVIELLPEKHGQYGLALH 1330 1340 1350 1360 1370 1380 1390 pF1KSD LIEAVEAISLPSL ::::::::::::: NP_036 LIEAVEAISLPSL 1390 1393 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:40:02 2016 done: Thu Nov 3 03:40:04 2016 Total Scan time: 17.270 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]