FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0841, 633 aa 1>>>pF1KSDA0841 633 - 633 aa - 633 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6068+/-0.000371; mu= 8.9834+/- 0.023 mean_var=144.4018+/-28.865, 0's: 0 Z-trim(117.8): 18 B-trim: 710 in 2/52 Lambda= 0.106730 statistics sampled from 30199 (30218) to 30199 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.354), width: 16 Scan time: 11.460 The best scores are: opt bits E(85289) NP_056117 (OMIM: 613432) HAUS augmin-like complex ( 633) 4194 657.8 3.3e-188 XP_011524986 (OMIM: 613432) PREDICTED: HAUS augmin ( 533) 3529 555.3 1.9e-157 >>NP_056117 (OMIM: 613432) HAUS augmin-like complex subu (633 aa) initn: 4194 init1: 4194 opt: 4194 Z-score: 3499.9 bits: 657.8 E(85289): 3.3e-188 Smith-Waterman score: 4194; 100.0% identity (100.0% similar) in 633 aa overlap (1-633:1-633) 10 20 30 40 50 60 pF1KSD MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD VLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPG 550 560 570 580 590 600 610 620 630 pF1KSD QAALSEELCQGLSLPQWRLRWVQAQGALQKLCS ::::::::::::::::::::::::::::::::: NP_056 QAALSEELCQGLSLPQWRLRWVQAQGALQKLCS 610 620 630 >>XP_011524986 (OMIM: 613432) PREDICTED: HAUS augmin-lik (533 aa) initn: 3529 init1: 3529 opt: 3529 Z-score: 2947.6 bits: 555.3 E(85289): 1.9e-157 Smith-Waterman score: 3529; 100.0% identity (100.0% similar) in 533 aa overlap (101-633:1-533) 80 90 100 110 120 130 pF1KSD SPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLR :::::::::::::::::::::::::::::: XP_011 MERDTEAQDTAMEQARQHTQDTQRRALLLR 10 20 30 140 150 160 170 180 190 pF1KSD AQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRT 40 50 60 70 80 90 200 210 220 230 240 250 pF1KSD ACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KSD AAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRST 160 170 180 190 200 210 320 330 340 350 360 370 pF1KSD LLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAG 220 230 240 250 260 270 380 390 400 410 420 430 pF1KSD HRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVV 280 290 300 310 320 330 440 450 460 470 480 490 pF1KSD PTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRG 340 350 360 370 380 390 500 510 520 530 540 550 pF1KSD SSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSLPPGLPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSLPPGLPTQ 400 410 420 430 440 450 560 570 580 590 600 610 pF1KSD ELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPGQAALSEELCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPGQAALSEELCQ 460 470 480 490 500 510 620 630 pF1KSD GLSLPQWRLRWVQAQGALQKLCS ::::::::::::::::::::::: XP_011 GLSLPQWRLRWVQAQGALQKLCS 520 530 633 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:40:43 2016 done: Thu Nov 3 03:40:45 2016 Total Scan time: 11.460 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]