FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0843, 683 aa 1>>>pF1KSDA0843 683 - 683 aa - 683 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2808+/-0.000467; mu= 7.3081+/- 0.029 mean_var=256.4590+/-55.084, 0's: 0 Z-trim(117.0): 445 B-trim: 92 in 2/56 Lambda= 0.080088 statistics sampled from 28148 (28634) to 28148 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.336), width: 16 Scan time: 11.540 The best scores are: opt bits E(85289) NP_001287944 (OMIM: 611305) actin-binding LIM prot ( 683) 4786 567.1 7.5e-161 NP_055760 (OMIM: 611305) actin-binding LIM protein ( 683) 4786 567.1 7.5e-161 XP_011535911 (OMIM: 611305) PREDICTED: actin-bindi ( 445) 3122 374.7 4.3e-103 NP_001287947 (OMIM: 611305) actin-binding LIM prot ( 650) 2905 349.8 1.9e-95 NP_001332787 (OMIM: 611305) actin-binding LIM prot ( 634) 2903 349.5 2.2e-95 XP_005268451 (OMIM: 611305) PREDICTED: actin-bindi ( 621) 2405 292.0 4.6e-78 NP_002304 (OMIM: 602330) actin-binding LIM protein ( 778) 2234 272.3 4.7e-72 NP_001003407 (OMIM: 602330) actin-binding LIM prot ( 718) 2232 272.1 5.3e-72 XP_011538105 (OMIM: 602330) PREDICTED: actin-bindi ( 765) 2232 272.1 5.5e-72 NP_001332788 (OMIM: 611305) actin-binding LIM prot ( 588) 2214 269.9 2e-71 NP_001332790 (OMIM: 611305) actin-binding LIM prot ( 588) 2214 269.9 2e-71 NP_001287957 (OMIM: 611305) actin-binding LIM prot ( 544) 2209 269.3 2.8e-71 NP_001332789 (OMIM: 611305) actin-binding LIM prot ( 572) 2209 269.3 2.9e-71 XP_016871744 (OMIM: 602330) PREDICTED: actin-bindi ( 703) 2198 268.1 7.9e-71 NP_001309815 (OMIM: 602330) actin-binding LIM prot ( 654) 2022 247.8 1e-64 XP_005269881 (OMIM: 602330) PREDICTED: actin-bindi ( 655) 2015 246.9 1.8e-64 XP_016871742 (OMIM: 602330) PREDICTED: actin-bindi ( 718) 2015 247.0 1.9e-64 XP_016871738 (OMIM: 602330) PREDICTED: actin-bindi ( 746) 1865 229.7 3.1e-59 XP_016864198 (OMIM: 612544) PREDICTED: actin-bindi ( 628) 1837 226.4 2.6e-58 NP_001309814 (OMIM: 602330) actin-binding LIM prot ( 666) 1825 225.0 7.2e-58 NP_001309813 (OMIM: 602330) actin-binding LIM prot ( 668) 1822 224.7 9.2e-58 XP_016864205 (OMIM: 612544) PREDICTED: actin-bindi ( 589) 1820 224.4 9.9e-58 XP_016864207 (OMIM: 612544) PREDICTED: actin-bindi ( 583) 1819 224.2 1.1e-57 XP_016864206 (OMIM: 612544) PREDICTED: actin-bindi ( 588) 1818 224.1 1.2e-57 XP_016864199 (OMIM: 612544) PREDICTED: actin-bindi ( 627) 1818 224.2 1.2e-57 NP_001309812 (OMIM: 602330) actin-binding LIM prot ( 683) 1818 224.2 1.3e-57 XP_016871741 (OMIM: 602330) PREDICTED: actin-bindi ( 730) 1818 224.2 1.3e-57 XP_016871739 (OMIM: 602330) PREDICTED: actin-bindi ( 743) 1818 224.2 1.4e-57 XP_016871745 (OMIM: 602330) PREDICTED: actin-bindi ( 669) 1815 223.8 1.6e-57 XP_016871740 (OMIM: 602330) PREDICTED: actin-bindi ( 732) 1815 223.9 1.7e-57 NP_001309816 (OMIM: 602330) actin-binding LIM prot ( 636) 1810 223.2 2.3e-57 XP_016871735 (OMIM: 602330) PREDICTED: actin-bindi ( 760) 1672 207.4 1.6e-52 XP_016864212 (OMIM: 612544) PREDICTED: actin-bindi ( 555) 1657 205.5 4.4e-52 XP_016864196 (OMIM: 612544) PREDICTED: actin-bindi ( 657) 1657 205.6 5e-52 XP_006713988 (OMIM: 612544) PREDICTED: actin-bindi ( 621) 1656 205.4 5.2e-52 XP_005248078 (OMIM: 612544) PREDICTED: actin-bindi ( 622) 1656 205.4 5.2e-52 XP_011511888 (OMIM: 612544) PREDICTED: actin-bindi ( 648) 1656 205.5 5.3e-52 XP_006713987 (OMIM: 612544) PREDICTED: actin-bindi ( 660) 1656 205.5 5.4e-52 XP_006713986 (OMIM: 612544) PREDICTED: actin-bindi ( 661) 1656 205.5 5.4e-52 XP_005248075 (OMIM: 612544) PREDICTED: actin-bindi ( 661) 1656 205.5 5.4e-52 XP_005248074 (OMIM: 612544) PREDICTED: actin-bindi ( 662) 1656 205.5 5.4e-52 XP_016864195 (OMIM: 612544) PREDICTED: actin-bindi ( 700) 1656 205.5 5.6e-52 XP_005248071 (OMIM: 612544) PREDICTED: actin-bindi ( 701) 1656 205.5 5.6e-52 NP_001123559 (OMIM: 612544) actin-binding LIM prot ( 531) 1646 204.2 1e-51 NP_001123560 (OMIM: 612544) actin-binding LIM prot ( 470) 1644 203.9 1.1e-51 XP_006713990 (OMIM: 612544) PREDICTED: actin-bindi ( 536) 1645 204.1 1.1e-51 XP_016864209 (OMIM: 612544) PREDICTED: actin-bindi ( 575) 1645 204.1 1.2e-51 XP_016864213 (OMIM: 612544) PREDICTED: actin-bindi ( 532) 1644 204.0 1.2e-51 XP_005248088 (OMIM: 612544) PREDICTED: actin-bindi ( 475) 1643 203.8 1.2e-51 XP_005248085 (OMIM: 612544) PREDICTED: actin-bindi ( 537) 1643 203.9 1.3e-51 >>NP_001287944 (OMIM: 611305) actin-binding LIM protein (683 aa) initn: 4786 init1: 4786 opt: 4786 Z-score: 3008.8 bits: 567.1 E(85289): 7.5e-161 Smith-Waterman score: 4786; 100.0% identity (100.0% similar) in 683 aa overlap (1-683:1-683) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 610 620 630 640 650 660 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: NP_001 TISEFDRLALWKRNELKKQARLF 670 680 >>NP_055760 (OMIM: 611305) actin-binding LIM protein 3 i (683 aa) initn: 4786 init1: 4786 opt: 4786 Z-score: 3008.8 bits: 567.1 E(85289): 7.5e-161 Smith-Waterman score: 4786; 100.0% identity (100.0% similar) in 683 aa overlap (1-683:1-683) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 610 620 630 640 650 660 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: NP_055 TISEFDRLALWKRNELKKQARLF 670 680 >>XP_011535911 (OMIM: 611305) PREDICTED: actin-binding L (445 aa) initn: 3122 init1: 3122 opt: 3122 Z-score: 1971.9 bits: 374.7 E(85289): 4.3e-103 Smith-Waterman score: 3122; 98.0% identity (98.9% similar) in 445 aa overlap (1-445:1-445) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY ::::::::::::::. . . . :: XP_011 TPTSYQAPKHFHIPGTKKLVPEGPP 430 440 >>NP_001287947 (OMIM: 611305) actin-binding LIM protein (650 aa) initn: 2882 init1: 2882 opt: 2905 Z-score: 1834.5 bits: 349.8 E(85289): 1.9e-95 Smith-Waterman score: 4477; 95.2% identity (95.2% similar) in 683 aa overlap (1-683:1-650) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS ::::::::::::::::::::::::::::::::::::::::: NP_001 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRS------------------- 370 380 390 400 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY :::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------------AGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY 410 420 430 440 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 450 460 470 480 490 500 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 510 520 530 540 550 560 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 570 580 590 600 610 620 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: NP_001 TISEFDRLALWKRNELKKQARLF 630 640 650 >>NP_001332787 (OMIM: 611305) actin-binding LIM protein (634 aa) initn: 3012 init1: 2886 opt: 2903 Z-score: 1833.3 bits: 349.5 E(85289): 2.2e-95 Smith-Waterman score: 4330; 92.8% identity (92.8% similar) in 683 aa overlap (1-683:1-634) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS :::::::::::::::::::::::::::::::::::::::::: NP_001 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSG------------------ 370 380 390 400 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY ::::::::::::::::::::::::::::: NP_001 -------------------------------DLSTATKSKTSEDISQTSKYSPIYSPDPY 410 420 430 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 440 450 460 470 480 490 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 500 510 520 530 540 550 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 560 570 580 590 600 610 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: NP_001 TISEFDRLALWKRNELKKQARLF 620 630 >>XP_005268451 (OMIM: 611305) PREDICTED: actin-binding L (621 aa) initn: 2208 init1: 2208 opt: 2405 Z-score: 1522.5 bits: 292.0 E(85289): 4.6e-78 Smith-Waterman score: 4242; 90.9% identity (90.9% similar) in 683 aa overlap (1-683:1-621) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVIC---- 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :: XP_005 ----------------------------------------------------------DI 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS 300 310 320 330 340 350 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY 360 370 380 390 400 410 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 420 430 440 450 460 470 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 480 490 500 510 520 530 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 540 550 560 570 580 590 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: XP_005 TISEFDRLALWKRNELKKQARLF 600 610 620 >>NP_002304 (OMIM: 602330) actin-binding LIM protein 1 i (778 aa) initn: 1706 init1: 729 opt: 2234 Z-score: 1414.5 bits: 272.3 E(85289): 4.7e-72 Smith-Waterman score: 2523; 52.7% identity (74.4% similar) in 730 aa overlap (2-683:76-778) 10 20 pF1KSD MNTSIPYQQNPYNPRGSSN--VIQCYRCGDT :. :. .: .:. :. ::.:..::. NP_002 GTSFTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEP 50 60 70 80 90 100 30 40 50 60 70 80 pF1KSD CKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFI :::::.::...::::.::::.:::: :::.:::.:: ::.:: :::..::::: .: .:. NP_002 CKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFV 110 120 130 140 150 160 90 100 110 120 130 140 pF1KSD TGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPS :::..:::.::::.::.:..:..::: ::.:::.:..:.:: :.: :.:: : . : NP_002 EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSS-PKETTFSS 170 180 190 200 210 220 150 160 170 180 190 200 pF1KSD HCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEYISKDGVPYCESDYHAQFGIK .:::: ..::.::.:::::::::..::::..:. .::::::::::.::::.::.. ::.: NP_002 NCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVK 230 240 250 260 270 280 210 220 230 240 250 260 pF1KSD CETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEK ::.: ..:.:.::::: :::::.:::: ::.::::::::::: :: :::: :::....:. NP_002 CEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEE 290 300 310 320 330 340 270 280 290 300 310 320 pF1KSD KLKHRRTSETSI-SPPGSSI-GSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLI ::. ::: :: : ::::: :::...: ::::::::.::::::.::::.::...::::: NP_002 KLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLI 350 360 370 380 390 400 330 340 350 360 370 380 pF1KSD SYEPHSRYMSDEMLERCGYGESLGTLSPY-SQDIYENLDLRQR---RASSPGYIDSPTYS .::: :. :: . ::: :::: : . :. :.:.: :..: : :.::.:: NP_002 TYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQ--DVRDRMIHRSTSQGSINSPVYS 410 420 430 440 450 460 390 400 410 420 430 440 pF1KSD RQGMSPTFSRSPHHYYRSG--PESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIY :....:: ::::.:..: : : :::.:: . : : ::: :::::::.: ::: NP_002 RHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIY 470 480 490 500 510 520 450 460 470 480 490 pF1KSD RKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPYYAS--ESEYWTYHGSPKV--P :::::::.:. : :..::.:::: . ::. .::: . :...: : : : NP_002 RKPPIYKQHAAL--AAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGP 530 540 550 560 570 580 500 510 520 530 540 pF1KSD RARRFSSGGEEDDFD---------RSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSS .: ::: :::: . ... ::.::.:.:::::::. .: ::: NP_002 DMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRE--------RSS 590 600 610 620 630 550 560 570 580 590 600 pF1KSD TSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSADLFHYDSM : .. :. .:.. :: . ::.::::.: :::::: :.:. .:.:. NP_002 ------LLASRYDSPINSA--SHIPS------SKTASLPGYGRNGLHRPVSTDFAQYNSY 640 650 660 670 610 620 630 640 pF1KSD NAVNWGMREY-------------------------KIYPYELLLVTTRGRNRLPKDVDRT . :. :.:.: ::.:::.:.::.::::.. ..:::: NP_002 GDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRT 680 690 700 710 720 730 650 660 670 680 pF1KSD RLERHLSQEEFYQVFGMTISEFDRLALWKRNELKKQARLF ::::::. : : ..:::.:.::::: ::.::..::.:.:: NP_002 RLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF 740 750 760 770 >>NP_001003407 (OMIM: 602330) actin-binding LIM protein (718 aa) initn: 1706 init1: 729 opt: 2232 Z-score: 1413.7 bits: 272.1 E(85289): 5.3e-72 Smith-Waterman score: 2521; 52.7% identity (74.7% similar) in 727 aa overlap (5-683:22-718) 10 20 30 40 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFH . . :.:..: . . ::.:..::. :::::.::...::: NP_001 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHP-SEKPVIHCHKCGEPCKGEVLRVQTKHFH 10 20 30 40 50 50 60 70 80 90 100 pF1KSD IRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHP :.::::.:::: :::.:::.:: ::.:: :::..::::: .: .:. :::..:::.:::: NP_001 IKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHP 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD KCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQS .::.:..:..::: ::.:::.:..:.:: :.: :.:: : . :.:::: ..::.::. NP_001 NCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSS-PKETTFSSNCAGCGRDIKNGQA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD LLALDKQWHVSCFKCQTCSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLE :::::::::..::::..:. .::::::::::.::::.::.. ::.:::.: ..:.:.::: NP_001 LLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD AGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSI-S :: :::::.:::: ::.::::::::::: :: :::: :::....:.::. ::: :: : NP_001 AGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD PPGSSI-GSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEML ::::: :::...: ::::::::.::::::.::::.::...:::::.::: :. NP_001 RPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQ 300 310 320 330 340 350 350 360 370 380 390 pF1KSD ERCGYGESLGTLSPY-SQDIYENLDLRQR---RASSPGYIDSPTYSRQGMSPTFSRSPHH :: . ::: :::: : . :. :.:.: :..: : :.::.:::....:: ::::.: NP_001 ERQSLGESPRTLSPTPSAEGYQ--DVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQH 360 370 380 390 400 410 400 410 420 430 440 450 pF1KSD YYRSG--PESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLST ..: : : :::.:: . : : ::: :::::::.: ::::::::::.:. : NP_001 FHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAAL-- 420 430 440 450 460 470 460 470 480 490 500 pF1KSD ATKSKTSEDISQTSKYSPIYSPDPYYAS--ESEYWTYHGSPKV----PRARRFSSGGEED :..::.:::: . ::. .::: . :...: : :. : .: ::: ::: NP_001 AAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWP--GPPSFAVVGPDMKRRSSGREED 480 490 500 510 520 530 510 520 530 540 550 560 pF1KSD DFD---------RSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGY : . ... ::.::.:.:::::::. .: ::: : .. : NP_001 DEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESR--------ERSS------LLASRY 540 550 560 570 570 580 590 600 610 pF1KSD EMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSADLFHYDSMNAVNWGMREY-- . .:.. :: . ::.::::.: :::::: :.:. .:.:.. :. :.:.: NP_001 DSPINSA--SHIPS------SKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQT 580 590 600 610 620 630 620 630 640 650 pF1KSD -----------------------KIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFY ::.:::.:.::.::::.. ..::::::::::. : : NP_001 LPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFR 640 650 660 670 680 690 660 670 680 pF1KSD QVFGMTISEFDRLALWKRNELKKQARLF ..:::.:.::::: ::.::..::.:.:: NP_001 EIFGMSIQEFDRLPLWRRNDMKKKAKLF 700 710 >>XP_011538105 (OMIM: 602330) PREDICTED: actin-binding L (765 aa) initn: 1706 init1: 729 opt: 2232 Z-score: 1413.4 bits: 272.1 E(85289): 5.5e-72 Smith-Waterman score: 2521; 52.7% identity (74.7% similar) in 727 aa overlap (5-683:69-765) 10 20 30 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEV . . :.:..: . . ::.:..::. ::::: XP_011 EPHGWREEEDQDLRRRRGESHRKKKEQPAGVAHPQDPHHP-SEKPVIHCHKCGEPCKGEV 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD VRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVI .::...::::.::::.:::: :::.:::.:: ::.:: :::..::::: .: .:. :::. XP_011 LRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVV 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD SALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGC .:::.::::.::.:..:..::: ::.:::.:..:.:: :.: :.:: : . :.:::: XP_011 TALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSS-PKETTFSSNCAGC 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD KEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEYISKDGVPYCESDYHAQFGIKCETCD ..::.::.:::::::::..::::..:. .::::::::::.::::.::.. ::.:::.: XP_011 GRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACH 220 230 240 250 260 270 220 230 240 250 260 270 pF1KSD RYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHR ..:.:.::::: :::::.:::: ::.::::::::::: :: :::: :::....:.::. XP_011 QFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPT 280 290 300 310 320 330 280 290 300 310 320 330 pF1KSD RTSETSI-SPPGSSI-GSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPH ::: :: : ::::: :::...: ::::::::.::::::.::::.::...:::::.::: XP_011 RTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPF 340 350 360 370 380 390 340 350 360 370 380 pF1KSD SRYMSDEMLERCGYGESLGTLSPY-SQDIYENLDLRQR---RASSPGYIDSPTYSRQGMS :. :: . ::: :::: : . :. :.:.: :..: : :.::.:::.... XP_011 YTSGYDDKQERQSLGESPRTLSPTPSAEGYQ--DVRDRMIHRSTSQGSINSPVYSRHSYT 400 410 420 430 440 450 390 400 410 420 430 440 pF1KSD PTFSRSPHHYYRSG--PESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPI :: ::::.:..: : : :::.:: . : : ::: :::::::.: :::::::: XP_011 PTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPI 460 470 480 490 500 510 450 460 470 480 490 500 pF1KSD YKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPYYAS--ESEYWTYHGSPKV----PRAR ::.:. : :..::.:::: . ::. .::: . :...: : :. : . XP_011 YKQHAAL--AAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWP--GPPSFAVVGPDMK 520 530 540 550 560 570 510 520 530 540 550 pF1KSD RFSSGGEEDDFD---------RSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSS : ::: :::: . ... ::.::.:.:::::::. .: ::: XP_011 RRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESR--------ERSS--- 580 590 600 610 560 570 580 590 600 610 pF1KSD REALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSADLFHYDSMNAV : .. :. .:.. :: . ::.::::.: :::::: :.:. .:.:.. : XP_011 ---LLASRYDSPINSA--SHIPS------SKTASLPGYGRNGLHRPVSTDFAQYNSYGDV 620 630 640 650 660 620 630 640 pF1KSD NWGMREY-------------------------KIYPYELLLVTTRGRNRLPKDVDRTRLE . :.:.: ::.:::.:.::.::::.. ..::::::: XP_011 SGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLE 670 680 690 700 710 720 650 660 670 680 pF1KSD RHLSQEEFYQVFGMTISEFDRLALWKRNELKKQARLF :::. : : ..:::.:.::::: ::.::..::.:.:: XP_011 RHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF 730 740 750 760 >>NP_001332788 (OMIM: 611305) actin-binding LIM protein (588 aa) initn: 3868 init1: 2171 opt: 2214 Z-score: 1403.5 bits: 269.9 E(85289): 2e-71 Smith-Waterman score: 3933; 86.1% identity (86.1% similar) in 683 aa overlap (1-683:1-588) 10 20 30 40 50 60 pF1KSD MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFFKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVIC---- 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI :: NP_001 ----------------------------------------------------------DI 370 380 390 400 410 420 pF1KSD YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSS ::::::::::::::::::::::::::::::::::::::::: NP_001 YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRS------------------- 300 310 320 330 430 440 450 460 470 480 pF1KSD TPTSYQAPKHFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY :::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------------AGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPY 340 350 360 370 380 490 500 510 520 530 540 pF1KSD YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD 390 400 410 420 430 440 550 560 570 580 590 600 pF1KSD PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPLISKSASLPAYRRNGLHRTPSA 450 460 470 480 490 500 610 620 630 640 650 660 pF1KSD DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGM 510 520 530 540 550 560 670 680 pF1KSD TISEFDRLALWKRNELKKQARLF ::::::::::::::::::::::: NP_001 TISEFDRLALWKRNELKKQARLF 570 580 683 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:41:21 2016 done: Thu Nov 3 03:41:23 2016 Total Scan time: 11.540 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]