FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0849, 953 aa 1>>>pF1KSDA0849 953 - 953 aa - 953 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6093+/-0.000924; mu= 9.8776+/- 0.056 mean_var=107.1158+/-21.747, 0's: 0 Z-trim(108.6): 21 B-trim: 562 in 1/50 Lambda= 0.123922 statistics sampled from 10322 (10337) to 10322 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.318), width: 16 Scan time: 4.420 The best scores are: opt bits E(32554) CCDS42164.1 CYLD gene_id:1540|Hs108|chr16 ( 953) 6486 1170.8 0 CCDS45482.1 CYLD gene_id:1540|Hs108|chr16 ( 956) 6470 1167.9 0 >>CCDS42164.1 CYLD gene_id:1540|Hs108|chr16 (953 aa) initn: 6486 init1: 6486 opt: 6486 Z-score: 6265.8 bits: 1170.8 E(32554): 0 Smith-Waterman score: 6486; 100.0% identity (100.0% similar) in 953 aa overlap (1-953:1-953) 10 20 30 40 50 60 pF1KSD MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHIN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DIIPESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DIIPESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLPFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLPFSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKENPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKENPP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLED 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD TPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNI 850 860 870 880 890 900 910 920 930 940 950 pF1KSD PQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK 910 920 930 940 950 >>CCDS45482.1 CYLD gene_id:1540|Hs108|chr16 (956 aa) initn: 4452 init1: 4452 opt: 6470 Z-score: 6250.3 bits: 1167.9 E(32554): 0 Smith-Waterman score: 6470; 99.7% identity (99.7% similar) in 956 aa overlap (1-953:1-956) 10 20 30 40 50 60 pF1KSD MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHIN 250 260 270 280 290 300 310 320 330 340 350 pF1KSD DIIP---ESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNG :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DIIPALSESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD SSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD FSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD NPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD PDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD CYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIM 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD KLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFME 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD KNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD LEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD PKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNG 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD FNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK 910 920 930 940 950 953 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:47:01 2016 done: Thu Nov 3 18:47:01 2016 Total Scan time: 4.420 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]