FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0851, 587 aa 1>>>pF1KSDA0851 587 - 587 aa - 587 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9818+/-0.00054; mu= 20.6654+/- 0.033 mean_var=68.1543+/-13.704, 0's: 0 Z-trim(106.5): 61 B-trim: 0 in 0/54 Lambda= 0.155356 statistics sampled from 14572 (14628) to 14572 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.528), E-opt: 0.2 (0.172), width: 16 Scan time: 7.220 The best scores are: opt bits E(85289) NP_054735 (OMIM: 606569) phosphatidylinositide pho ( 587) 3917 887.9 0 NP_001306002 (OMIM: 606569) phosphatidylinositide ( 484) 3258 740.2 3.7e-213 NP_001306001 (OMIM: 606569) phosphatidylinositide ( 526) 3213 730.1 4.3e-210 XP_011531802 (OMIM: 606569) PREDICTED: phosphatidy ( 526) 3213 730.1 4.3e-210 XP_006717783 (OMIM: 609389) PREDICTED: phosphatidy ( 641) 895 210.6 1.2e-53 XP_011537827 (OMIM: 609389) PREDICTED: phosphatidy (1036) 895 210.8 1.8e-53 XP_011537830 (OMIM: 609389) PREDICTED: phosphatidy (1036) 895 210.8 1.8e-53 XP_016871425 (OMIM: 609389) PREDICTED: phosphatidy (1036) 895 210.8 1.8e-53 XP_016871424 (OMIM: 609389) PREDICTED: phosphatidy (1036) 895 210.8 1.8e-53 XP_011537829 (OMIM: 609389) PREDICTED: phosphatidy (1094) 895 210.8 1.9e-53 XP_011537826 (OMIM: 609389) PREDICTED: phosphatidy (1120) 895 210.8 1.9e-53 NP_055752 (OMIM: 609389) phosphatidylinositide pho (1132) 895 210.8 1.9e-53 XP_016883994 (OMIM: 604297,615530) PREDICTED: syna (1303) 634 152.4 8.8e-36 NP_001153778 (OMIM: 604297,615530) synaptojanin-1 (1526) 634 152.4 9.9e-36 XP_016883988 (OMIM: 604297,615530) PREDICTED: syna (1565) 634 152.4 1e-35 XP_016883984 (OMIM: 604297,615530) PREDICTED: syna (1607) 634 152.4 1e-35 XP_016883993 (OMIM: 604297,615530) PREDICTED: syna (1269) 632 151.9 1.2e-35 XP_016883992 (OMIM: 604297,615530) PREDICTED: syna (1282) 632 151.9 1.2e-35 XP_016883991 (OMIM: 604297,615530) PREDICTED: syna (1294) 632 151.9 1.2e-35 NP_001153774 (OMIM: 604297,615530) synaptojanin-1 (1295) 632 151.9 1.2e-35 XP_016883990 (OMIM: 604297,615530) PREDICTED: syna (1310) 632 151.9 1.2e-35 XP_016883989 (OMIM: 604297,615530) PREDICTED: syna (1311) 632 151.9 1.2e-35 NP_982271 (OMIM: 604297,615530) synaptojanin-1 iso (1350) 632 151.9 1.2e-35 XP_016883987 (OMIM: 604297,615530) PREDICTED: syna (1531) 632 152.0 1.4e-35 XP_016883985 (OMIM: 604297,615530) PREDICTED: syna (1544) 632 152.0 1.4e-35 XP_016883983 (OMIM: 604297,615530) PREDICTED: syna (1557) 632 152.0 1.4e-35 XP_016883986 (OMIM: 604297,615530) PREDICTED: syna (1596) 632 152.0 1.4e-35 NP_003886 (OMIM: 604297,615530) synaptojanin-1 iso (1612) 632 152.0 1.4e-35 XP_011534529 (OMIM: 609410) PREDICTED: synaptojani (1158) 598 144.3 2.2e-33 XP_011534532 (OMIM: 609410) PREDICTED: synaptojani (1243) 598 144.3 2.3e-33 XP_006715655 (OMIM: 609410) PREDICTED: synaptojani (1288) 598 144.3 2.3e-33 XP_011534526 (OMIM: 609410) PREDICTED: synaptojani (1451) 598 144.3 2.6e-33 NP_003889 (OMIM: 609410) synaptojanin-2 isoform 1 (1496) 598 144.4 2.6e-33 NP_001171559 (OMIM: 609410) synaptojanin-2 isoform (1259) 380 95.4 1.2e-18 XP_011534527 (OMIM: 609410) PREDICTED: synaptojani (1259) 380 95.4 1.2e-18 XP_011537831 (OMIM: 609389) PREDICTED: phosphatidy ( 646) 252 66.5 3e-10 XP_016867082 (OMIM: 216340,609390,611228,612577,61 ( 597) 249 65.8 4.5e-10 XP_016867081 (OMIM: 216340,609390,611228,612577,61 ( 724) 249 65.9 5.3e-10 XP_016867080 (OMIM: 216340,609390,611228,612577,61 ( 743) 249 65.9 5.4e-10 XP_011534583 (OMIM: 216340,609390,611228,612577,61 ( 886) 249 66.0 6.2e-10 NP_055660 (OMIM: 216340,609390,611228,612577,61269 ( 907) 249 66.0 6.3e-10 XP_011534528 (OMIM: 609410) PREDICTED: synaptojani (1165) 226 60.9 2.7e-08 XP_005267255 (OMIM: 609410) PREDICTED: synaptojani (1165) 226 60.9 2.7e-08 XP_011534530 (OMIM: 609410) PREDICTED: synaptojani (1113) 163 46.8 0.00047 XP_016866895 (OMIM: 609410) PREDICTED: synaptojani (1113) 163 46.8 0.00047 XP_005267256 (OMIM: 609410) PREDICTED: synaptojani (1113) 163 46.8 0.00047 >>NP_054735 (OMIM: 606569) phosphatidylinositide phospha (587 aa) initn: 3917 init1: 3917 opt: 3917 Z-score: 4744.9 bits: 887.9 E(85289): 0 Smith-Waterman score: 3917; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587) 10 20 30 40 50 60 pF1KSD MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPPSAVTRPIFGI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 YYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLL 490 500 510 520 530 540 550 560 570 580 pF1KSD MAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID ::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID 550 560 570 580 >>NP_001306002 (OMIM: 606569) phosphatidylinositide phos (484 aa) initn: 3258 init1: 3258 opt: 3258 Z-score: 3947.8 bits: 740.2 E(85289): 3.7e-213 Smith-Waterman score: 3258; 100.0% identity (100.0% similar) in 484 aa overlap (104-587:1-484) 80 90 100 110 120 130 pF1KSD VITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYF :::::::::::::::::::::::::::::: NP_001 MLHLTDIQLQDNKTFLAMLNHVLNVDGFYF 10 20 30 140 150 160 170 180 190 pF1KSD STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGF 40 50 60 70 80 90 200 210 220 230 240 250 pF1KSD ITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASF 100 110 120 130 140 150 260 270 280 290 300 310 pF1KSD VQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGS 160 170 180 190 200 210 320 330 340 350 360 370 pF1KSD EKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KSD AGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKI 280 290 300 310 320 330 440 450 460 470 480 490 pF1KSD YKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKNAWADNANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQD 340 350 360 370 380 390 500 510 520 530 540 550 pF1KSD SIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIDLFLGNYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYV 400 410 420 430 440 450 560 570 580 pF1KSD LFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID :::::::::::::::::::::::::::::::::: NP_001 LFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID 460 470 480 >>NP_001306001 (OMIM: 606569) phosphatidylinositide phos (526 aa) initn: 3213 init1: 3213 opt: 3213 Z-score: 3892.8 bits: 730.1 E(85289): 4.3e-210 Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 477 aa overlap (111-587:50-526) 90 100 110 120 130 140 pF1KSD VGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLT :::::::::::::::::::::::::::::: NP_001 QRLPLQSRKMFLLQLSQDQYLVYWAQSIWWQLQDNKTFLAMLNHVLNVDGFYFSTTYDLT 20 30 40 50 60 70 150 160 170 180 190 200 pF1KSD HTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCS 80 90 100 110 120 130 210 220 230 240 250 260 pF1KSD INGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSI 140 150 160 170 180 190 270 280 290 300 310 320 pF1KSD PVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQT 200 210 220 230 240 250 330 340 350 360 370 380 pF1KSD FATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVAN 260 270 280 290 300 310 390 400 410 420 430 440 pF1KSD QEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWAD 320 330 340 350 360 370 450 460 470 480 490 500 pF1KSD NANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG 380 390 400 410 420 430 510 520 530 540 550 560 pF1KSD NYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVAS 440 450 460 470 480 490 570 580 pF1KSD IGTFFIILYNGKDFVDAPRLVQKEKID ::::::::::::::::::::::::::: NP_001 IGTFFIILYNGKDFVDAPRLVQKEKID 500 510 520 >>XP_011531802 (OMIM: 606569) PREDICTED: phosphatidylino (526 aa) initn: 3213 init1: 3213 opt: 3213 Z-score: 3892.8 bits: 730.1 E(85289): 4.3e-210 Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 477 aa overlap (111-587:50-526) 90 100 110 120 130 140 pF1KSD VGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLT :::::::::::::::::::::::::::::: XP_011 QRLPLQSRKMFLLQLSQDQYLVYWAQSIWWQLQDNKTFLAMLNHVLNVDGFYFSTTYDLT 20 30 40 50 60 70 150 160 170 180 190 200 pF1KSD HTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCS 80 90 100 110 120 130 210 220 230 240 250 260 pF1KSD INGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSI 140 150 160 170 180 190 270 280 290 300 310 320 pF1KSD PVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQT 200 210 220 230 240 250 330 340 350 360 370 380 pF1KSD FATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FATMVSSLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVAN 260 270 280 290 300 310 390 400 410 420 430 440 pF1KSD QEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWAD 320 330 340 350 360 370 450 460 470 480 490 500 pF1KSD NANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NANACAKQYAGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG 380 390 400 410 420 430 510 520 530 540 550 560 pF1KSD NYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVAS 440 450 460 470 480 490 570 580 pF1KSD IGTFFIILYNGKDFVDAPRLVQKEKID ::::::::::::::::::::::::::: XP_011 IGTFFIILYNGKDFVDAPRLVQKEKID 500 510 520 >>XP_006717783 (OMIM: 609389) PREDICTED: phosphatidylino (641 aa) initn: 956 init1: 438 opt: 895 Z-score: 1083.8 bits: 210.6 E(85289): 1.2e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:146-576) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_006 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 120 130 140 150 160 170 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_006 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 180 190 200 210 220 230 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_006 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 240 250 260 270 280 290 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_006 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 300 310 320 330 340 350 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_006 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 360 370 380 390 400 410 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_006 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 420 430 440 450 460 470 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_006 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 480 490 500 510 520 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_006 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 530 540 550 560 570 580 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_006 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPRKPPTLSTAGKRL 590 600 610 620 630 640 >>XP_011537827 (OMIM: 609389) PREDICTED: phosphatidylino (1036 aa) initn: 949 init1: 438 opt: 895 Z-score: 1080.9 bits: 210.8 E(85289): 1.8e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:50-480) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_011 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 20 30 40 50 60 70 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_011 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 80 90 100 110 120 130 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_011 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 140 150 160 170 180 190 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_011 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 200 210 220 230 240 250 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_011 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 260 270 280 290 300 310 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_011 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 320 330 340 350 360 370 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_011 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 380 390 400 410 420 430 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_011 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 440 450 460 470 480 490 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_011 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAY 500 510 520 530 540 550 >>XP_011537830 (OMIM: 609389) PREDICTED: phosphatidylino (1036 aa) initn: 949 init1: 438 opt: 895 Z-score: 1080.9 bits: 210.8 E(85289): 1.8e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:50-480) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_011 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 20 30 40 50 60 70 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_011 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 80 90 100 110 120 130 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_011 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 140 150 160 170 180 190 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_011 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 200 210 220 230 240 250 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_011 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 260 270 280 290 300 310 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_011 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 320 330 340 350 360 370 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_011 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 380 390 400 410 420 430 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_011 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 440 450 460 470 480 490 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_011 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAY 500 510 520 530 540 550 >>XP_016871425 (OMIM: 609389) PREDICTED: phosphatidylino (1036 aa) initn: 949 init1: 438 opt: 895 Z-score: 1080.9 bits: 210.8 E(85289): 1.8e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:50-480) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_016 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 20 30 40 50 60 70 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_016 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 80 90 100 110 120 130 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_016 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 140 150 160 170 180 190 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_016 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 200 210 220 230 240 250 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_016 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 260 270 280 290 300 310 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_016 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 320 330 340 350 360 370 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_016 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 380 390 400 410 420 430 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_016 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 440 450 460 470 480 490 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_016 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAY 500 510 520 530 540 550 >>XP_016871424 (OMIM: 609389) PREDICTED: phosphatidylino (1036 aa) initn: 949 init1: 438 opt: 895 Z-score: 1080.9 bits: 210.8 E(85289): 1.8e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:50-480) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_016 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 20 30 40 50 60 70 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_016 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 80 90 100 110 120 130 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_016 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 140 150 160 170 180 190 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_016 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 200 210 220 230 240 250 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_016 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 260 270 280 290 300 310 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_016 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 320 330 340 350 360 370 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_016 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 380 390 400 410 420 430 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_016 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 440 450 460 470 480 490 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_016 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAY 500 510 520 530 540 550 >>XP_011537829 (OMIM: 609389) PREDICTED: phosphatidylino (1094 aa) initn: 949 init1: 438 opt: 895 Z-score: 1080.6 bits: 210.8 E(85289): 1.9e-53 Smith-Waterman score: 1010; 38.0% identity (66.8% similar) in 437 aa overlap (101-509:108-538) 80 90 100 110 120 130 pF1KSD YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLNHVLNVDG :: . . . . . . . .:. .. .. XP_011 KPEKIIPSPDDSKFLLKTFTHIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSES 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELS--AQPEVHRFALP ::.: :::::...:: : . : . : ...:.:: :: .....:. . :.: . .: XP_011 FYYSLTYDLTNSVQRQS--TGERDGRPLWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIP 140 150 160 170 180 190 190 200 210 220 pF1KSD VLHGFITMHSCSIN-------------------------GKYFDWILISRRSCFRAGVRY ...::. .. .: : :::::: :::.:: XP_011 MIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALISRRSRHRAGMRY 200 210 220 230 240 250 230 240 250 260 270 280 pF1KSD YVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKYKPLPQISKVAN ::.:..:..::.:::::..: .. ::::::::.:::::: . .:.: :.... . XP_011 KRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQV-GYRYNPRPRLDRSEK 260 270 280 290 300 310 290 300 310 320 330 340 pF1KSD H-MDGFQRHFDSQVIIYGKQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHK . . : ::. :. :: :::::::..: : :: . ... .: .... . :..::::. XP_011 ETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNNSHLTYVSFDFHE 320 330 340 350 360 370 350 360 370 380 390 400 pF1KSD ECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSL .:..:... .. : : . .. .... :: :: :. .:::.:: :::::::::::.:. XP_011 HCRGMKFENVQTLTDAIYDIILDMKWCWVDEAG-VICKQEGIFRVNCMDCLDRTNVVQAA 380 390 400 410 420 430 410 420 430 440 450 460 pF1KSD LARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRT .:: .. ::..:::. : : . ..::. ::.:... ..:::::.::: ::::: XP_011 IARVVMEQQLKKLGVMPPEQPLPVK--CNRIYQIMWANNGDSISRQYAGTAALKGDFTRT 440 450 460 470 480 490 470 480 490 500 510 520 pF1KSD GKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESHSPLSVPRDWKFL :.: :.. :: :: ::: : :.:..:: :::. : ...: : XP_011 GERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHK 500 510 520 530 540 550 530 540 550 560 570 580 pF1KSD ALPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGVASIGTFFIILYNGKDFVDAPRLVQ XP_011 ENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLSNSAY 560 570 580 590 600 610 587 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:45:23 2016 done: Thu Nov 3 03:45:24 2016 Total Scan time: 7.220 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]