FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0857, 653 aa 1>>>pF1KSDA0857 653 - 653 aa - 653 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5334+/-0.000353; mu= 4.0347+/- 0.022 mean_var=164.5343+/-33.615, 0's: 0 Z-trim(119.5): 34 B-trim: 132 in 1/54 Lambda= 0.099988 statistics sampled from 33583 (33619) to 33583 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.394), width: 16 Scan time: 10.450 The best scores are: opt bits E(85289) NP_056285 (OMIM: 605536) rab11 family-interacting ( 653) 4276 629.1 1.5e-179 XP_011531056 (OMIM: 605536) PREDICTED: rab11 famil ( 574) 3458 511.1 4.4e-144 XP_005264308 (OMIM: 605536) PREDICTED: rab11 famil (1218) 3457 511.1 9.3e-144 XP_011531057 (OMIM: 605536) PREDICTED: rab11 famil ( 546) 3449 509.8 1e-143 XP_011531058 (OMIM: 605536) PREDICTED: rab11 famil ( 540) 3448 509.7 1.1e-143 XP_005264310 (OMIM: 605536) PREDICTED: rab11 famil ( 531) 3445 509.2 1.5e-143 XP_006712048 (OMIM: 605536) PREDICTED: rab11 famil (1249) 3451 510.3 1.7e-143 XP_005264309 (OMIM: 605536) PREDICTED: rab11 famil (1324) 3447 509.7 2.7e-143 XP_011531055 (OMIM: 605536) PREDICTED: rab11 famil (1118) 2493 372.1 6.3e-102 XP_016859277 (OMIM: 605536) PREDICTED: rab11 famil (1073) 2281 341.5 9.7e-93 NP_079427 (OMIM: 608737) rab11 family-interacting ( 649) 658 107.2 1.9e-22 XP_016869358 (OMIM: 608737) PREDICTED: rab11 famil (1175) 658 107.4 3.1e-22 NP_001002814 (OMIM: 608737) rab11 family-interacti (1283) 658 107.4 3.4e-22 XP_016871415 (OMIM: 608599) PREDICTED: rab11 famil ( 433) 473 80.5 1.4e-14 NP_055719 (OMIM: 608599) rab11 family-interacting ( 512) 473 80.5 1.7e-14 NP_001317096 (OMIM: 608599) rab11 family-interacti ( 532) 473 80.5 1.7e-14 >>NP_056285 (OMIM: 605536) rab11 family-interacting prot (653 aa) initn: 4276 init1: 4276 opt: 4276 Z-score: 3344.6 bits: 629.1 E(85289): 1.5e-179 Smith-Waterman score: 4276; 100.0% identity (100.0% similar) in 653 aa overlap (1-653:1-653) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL 550 560 570 580 590 600 610 620 630 640 650 pF1KSD THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK 610 620 630 640 650 >>XP_011531056 (OMIM: 605536) PREDICTED: rab11 family-in (574 aa) initn: 3479 init1: 3444 opt: 3458 Z-score: 2707.7 bits: 511.1 E(85289): 4.4e-144 Smith-Waterman score: 3458; 98.7% identity (98.9% similar) in 534 aa overlap (1-530:1-534) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPS----PHPVKPLSAAPVE ::::::::::::::::::::::::::::::::::::::::::: :.: :: XP_011 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSLDVSPQPPPPLLPLLPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD GSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAK XP_011 PPPPPPLKPPHLDYWVLPTRSSPLCRATPSSRSS 550 560 570 >>XP_005264308 (OMIM: 605536) PREDICTED: rab11 family-in (1218 aa) initn: 3444 init1: 3444 opt: 3457 Z-score: 2701.9 bits: 511.1 E(85289): 9.3e-144 Smith-Waterman score: 3459; 90.9% identity (93.2% similar) in 591 aa overlap (1-575:1-591) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLS-AAPVEGSP ::::::::::::::::::::::::::::::::::::::::::: ..: :.: .. : XP_005 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSASRASPTPLASPGKALP 490 500 510 520 530 540 540 550 560 570 580 pF1KSD D-------------RKQSRSSLSIALSSGLEK--LKTVTSGSIQPVTQAPQAGQMVDTKR . : ..:: . . ::: :. :.. . :: XP_005 EWDNTFNVFAASRLRPEARSEILAPAGVGLEAAGLQDPGPGAMTAKAAEPQGEPGGGGGG 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTL XP_005 GGGGGGRGGSSVWLEPRVPLDLGPNHQSASAADPGLLGSVGAGLPSSSAQLQLRASGSEP 610 620 630 640 650 660 >-- initn: 977 init1: 858 opt: 858 Z-score: 675.7 bits: 136.2 E(85289): 6.7e-31 Smith-Waterman score: 866; 53.9% identity (66.1% similar) in 345 aa overlap (335-653:904-1218) 310 320 330 340 350 pF1KSD TYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYN-----EEPQGP-VRHRSSI :: ....::.. : :..: .. .. . XP_005 EDASPPVSGPCLSAPASCPEGPAPIPCHSKSLALQSQHIWGTPEVGEGPEAPEAQGQDPV 880 890 900 910 920 930 360 370 380 390 400 pF1KSD S---GSLPSSGSLQA---VSSR-----FSEEG---PRSTDDTWPRGSRSNSSSEAVLGQE . ::: :. : :: ::.. : .: : : ... : ::: .: : : XP_005 GEGLGSL-SATSQQADVWVSKEDALNPFLFQGSRDPPSLSSASPPGSRESSIHS---GPE 940 950 960 970 980 410 420 430 440 450 pF1KSD ELSAQAKV------LAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEER :: . . : : ::: ..:. : .:.. : :...:: .: XP_005 ELPTPPEPDFPPPPLPPWASH---HRGGPSPPCSPLSEAWPLTTSSAPPGE--------- 990 1000 1010 1020 1030 460 470 480 490 500 510 pF1KSD KPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDP : .:. :. : . : : . ::: : : :..: XP_005 -P--ALLPGPHE--PSPPGGSPALLREDLAAATPASPLVLLPLET---------RPAEEP 1040 1050 1060 1070 1080 520 530 540 550 560 570 pF1KSD TQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPSASPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 1090 1100 1110 1120 1130 1140 580 590 600 610 620 630 pF1KSD MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM 1150 1160 1170 1180 1190 1200 640 650 pF1KSD ETSPTLLQIPPGPPK ::::::::::::::: XP_005 ETSPTLLQIPPGPPK 1210 >>XP_011531057 (OMIM: 605536) PREDICTED: rab11 family-in (546 aa) initn: 3444 init1: 3444 opt: 3449 Z-score: 2701.0 bits: 509.8 E(85289): 1e-143 Smith-Waterman score: 3449; 97.6% identity (98.5% similar) in 541 aa overlap (1-539:1-535) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAP--VEGS ::::::::::::::::::::::::::::::::::::::::::: :...: .::. XP_011 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPS------LDVSPQCLEGQ 490 500 510 520 530 540 550 560 570 580 590 pF1KSD PDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYY : XP_011 PHPPGLPWESPA 540 >>XP_011531058 (OMIM: 605536) PREDICTED: rab11 family-in (540 aa) initn: 3444 init1: 3444 opt: 3448 Z-score: 2700.3 bits: 509.7 E(85289): 1.1e-143 Smith-Waterman score: 3448; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD ::::::::::::::::::::::::::::::::::::::::::: : XP_011 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSRLPRCCHCCRCRHHRRP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL >>XP_005264310 (OMIM: 605536) PREDICTED: rab11 family-in (531 aa) initn: 3479 init1: 3445 opt: 3445 Z-score: 2698.1 bits: 509.2 E(85289): 1.5e-143 Smith-Waterman score: 3445; 99.4% identity (99.4% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD :::::::::::::::::::::::::::::::::::::::::: : XP_005 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPRATPSSRSS 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL >>XP_006712048 (OMIM: 605536) PREDICTED: rab11 family-in (1249 aa) initn: 3444 init1: 3444 opt: 3451 Z-score: 2697.1 bits: 510.3 E(85289): 1.7e-143 Smith-Waterman score: 3451; 92.2% identity (96.0% similar) in 576 aa overlap (1-576:1-569) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD ::::::::::::::::::::::::::::::::::::::::::: :...: ...: XP_006 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPS------LDVSP-QSNPF 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL .. ..... : .: ... .: :... .: XP_006 FEELIADIALNSPSPAPSLPSASRASPTPLASPGKALPEWDNTFNVFAASRLRPEARSEI 540 550 560 570 580 590 610 620 630 640 650 pF1KSD THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK XP_006 LAPAGVGLEAAGLQDPGPGAMTAKAAEPQGEPGGGGGGGGGGGGRGGSSVWLEPRVPLDL 600 610 620 630 640 650 >-- initn: 974 init1: 858 opt: 858 Z-score: 675.6 bits: 136.2 E(85289): 6.8e-31 Smith-Waterman score: 866; 53.9% identity (66.1% similar) in 345 aa overlap (335-653:935-1249) 310 320 330 340 350 pF1KSD TYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYN-----EEPQGP-VRHRSSI :: ....::.. : :..: .. .. . XP_006 EDASPPVSGPCLSAPASCPEGPAPIPCHSKSLALQSQHIWGTPEVGEGPEAPEAQGQDPV 910 920 930 940 950 960 360 370 380 390 400 pF1KSD S---GSLPSSGSLQA---VSSR-----FSEEG---PRSTDDTWPRGSRSNSSSEAVLGQE . ::: :. : :: ::.. : .: : : ... : ::: .: : : XP_006 GEGLGSL-SATSQQADVWVSKEDALNPFLFQGSRDPPSLSSASPPGSRESSIHS---GPE 970 980 990 1000 1010 1020 410 420 430 440 450 pF1KSD ELSAQAKV------LAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEER :: . . : : ::: ..:. : .:.. : :...:: .: XP_006 ELPTPPEPDFPPPPLPPWASH---HRGGPSPPCSPLSEAWPLTTSSAPPGE--------- 1030 1040 1050 1060 460 470 480 490 500 510 pF1KSD KPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDP : .:. :. : . : : . ::: : : :..: XP_006 -P--ALLPGPHE--PSPPGGSPALLREDLAAATPASPLVLLPLET---------RPAEEP 1070 1080 1090 1100 1110 520 530 540 550 560 570 pF1KSD TQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPSASPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 1120 1130 1140 1150 1160 1170 580 590 600 610 620 630 pF1KSD MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM 1180 1190 1200 1210 1220 1230 640 650 pF1KSD ETSPTLLQIPPGPPK ::::::::::::::: XP_006 ETSPTLLQIPPGPPK 1240 >>XP_005264309 (OMIM: 605536) PREDICTED: rab11 family-in (1324 aa) initn: 3444 init1: 3444 opt: 3447 Z-score: 2693.6 bits: 509.7 E(85289): 2.7e-143 Smith-Waterman score: 3454; 90.7% identity (92.7% similar) in 590 aa overlap (1-574:1-590) 10 20 30 40 50 60 pF1KSD MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 430 440 450 460 470 480 490 500 510 520 pF1KSD SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPS--------------PH- ::::::::::::::::::::::::::::::::::::::::::: :: XP_005 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSLDVSPQVESDPAALPHH 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD -PVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKR : .: . :: .: :. .: .: .... . : . : XP_005 LPCSPWAPAPPTPAPTAAPMLSTNLFAAASPAAATAAAAATTAAPEATPPGLLGLTNPFL 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD LKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTL XP_005 TSLQSNPFFEELIADIALNSPSPAPSLPSASRASPTPLASPGKALPEWDNTFNVFAASRL 610 620 630 640 650 660 >-- initn: 974 init1: 858 opt: 858 Z-score: 675.2 bits: 136.2 E(85289): 7.2e-31 Smith-Waterman score: 866; 53.9% identity (66.1% similar) in 345 aa overlap (335-653:1010-1324) 310 320 330 340 350 pF1KSD TYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYN-----EEPQGP-VRHRSSI :: ....::.. : :..: .. .. . XP_005 EDASPPVSGPCLSAPASCPEGPAPIPCHSKSLALQSQHIWGTPEVGEGPEAPEAQGQDPV 980 990 1000 1010 1020 1030 360 370 380 390 400 pF1KSD S---GSLPSSGSLQA---VSSR-----FSEEG---PRSTDDTWPRGSRSNSSSEAVLGQE . ::: :. : :: ::.. : .: : : ... : ::: .: : : XP_005 GEGLGSL-SATSQQADVWVSKEDALNPFLFQGSRDPPSLSSASPPGSRESSIHS---GPE 1040 1050 1060 1070 1080 1090 410 420 430 440 450 pF1KSD ELSAQAKV------LAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEER :: . . : : ::: ..:. : .:.. : :...:: .: XP_005 ELPTPPEPDFPPPPLPPWASH---HRGGPSPPCSPLSEAWPLTTSSAPPGE--------- 1100 1110 1120 1130 1140 460 470 480 490 500 510 pF1KSD KPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDP : .:. :. : . : : . ::: : : :..: XP_005 -P--ALLPGPHE--PSPPGGSPALLREDLAAATPASPLVLLPLET---------RPAEEP 1150 1160 1170 1180 520 530 540 550 560 570 pF1KSD TQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPSASPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 1190 1200 1210 1220 1230 1240 580 590 600 610 620 630 pF1KSD MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM 1250 1260 1270 1280 1290 1300 640 650 pF1KSD ETSPTLLQIPPGPPK ::::::::::::::: XP_005 ETSPTLLQIPPGPPK 1310 1320 >>XP_011531055 (OMIM: 605536) PREDICTED: rab11 family-in (1118 aa) initn: 2514 init1: 2486 opt: 2493 Z-score: 1951.0 bits: 372.1 E(85289): 6.3e-102 Smith-Waterman score: 2493; 89.4% identity (94.7% similar) in 433 aa overlap (144-576:13-438) 120 130 140 150 160 170 pF1KSD HRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNL .::::::::::::::::::::::::::::: XP_011 MSLVQTQMKAGFRWYKLHSKPGKKEKERGEIEVTIQFTRNNL 10 20 30 40 180 190 200 210 220 230 pF1KSD SASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKG 50 60 70 80 90 100 240 250 260 270 280 290 pF1KSD FFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDS 110 120 130 140 150 160 300 310 320 330 340 350 pF1KSD AQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVR 170 180 190 200 210 220 360 370 380 390 400 410 pF1KSD HRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVL 230 240 250 260 270 280 420 430 440 450 460 470 pF1KSD APGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLS 290 300 310 320 330 340 480 490 500 510 520 530 pF1KSD RSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAA :::::::::::::::::::::::::::::::::::::::::::::::::: :... XP_011 RSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPS------LDVS 350 360 370 380 390 540 550 560 570 580 590 pF1KSD PVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQ : ...: .. ..... : .: ... .: :... .: XP_011 P-QSNPFFEELIADIALNSPSPAPSLPSASRASPTPLASPGKALPEWDNTFNVFAASRLR 400 410 420 430 440 450 600 610 620 630 640 650 pF1KSD SAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK XP_011 PEARSEILAPAGVGLEAAGLQDPGPGAMTAKAAEPQGEPGGGGGGGGGGGGRGGSSVWLE 460 470 480 490 500 510 >-- initn: 974 init1: 858 opt: 858 Z-score: 676.3 bits: 136.2 E(85289): 6.2e-31 Smith-Waterman score: 866; 53.9% identity (66.1% similar) in 345 aa overlap (335-653:804-1118) 310 320 330 340 350 pF1KSD TYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYN-----EEPQGP-VRHRSSI :: ....::.. : :..: .. .. . XP_011 EDASPPVSGPCLSAPASCPEGPAPIPCHSKSLALQSQHIWGTPEVGEGPEAPEAQGQDPV 780 790 800 810 820 830 360 370 380 390 400 pF1KSD S---GSLPSSGSLQA---VSSR-----FSEEG---PRSTDDTWPRGSRSNSSSEAVLGQE . ::: :. : :: ::.. : .: : : ... : ::: .: : : XP_011 GEGLGSL-SATSQQADVWVSKEDALNPFLFQGSRDPPSLSSASPPGSRESSIHS---GPE 840 850 860 870 880 410 420 430 440 450 pF1KSD ELSAQAKV------LAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEER :: . . : : ::: ..:. : .:.. : :...:: .: XP_011 ELPTPPEPDFPPPPLPPWASH---HRGGPSPPCSPLSEAWPLTTSSAPPGE--------- 890 900 910 920 930 460 470 480 490 500 510 pF1KSD KPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDP : .:. :. : . : : . ::: : : :..: XP_011 -P--ALLPGPHE--PSPPGGSPALLREDLAAATPASPLVLLPLET---------RPAEEP 940 950 960 970 980 520 530 540 550 560 570 pF1KSD TQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPSASPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 990 1000 1010 1020 1030 1040 580 590 600 610 620 630 pF1KSD MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM 1050 1060 1070 1080 1090 1100 640 650 pF1KSD ETSPTLLQIPPGPPK ::::::::::::::: XP_011 ETSPTLLQIPPGPPK 1110 >>XP_016859277 (OMIM: 605536) PREDICTED: rab11 family-in (1073 aa) initn: 2302 init1: 2274 opt: 2281 Z-score: 1786.0 bits: 341.5 E(85289): 9.7e-93 Smith-Waterman score: 2281; 88.8% identity (94.2% similar) in 400 aa overlap (177-576:1-393) 150 160 170 180 190 200 pF1KSD KLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLE :::::::::::::::::::::::::::::: XP_016 MFDLSMKDKPRSPFSKIRDKMKGKKKYDLE 10 20 30 210 220 230 240 250 260 pF1KSD SASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLA 40 50 60 70 80 90 270 280 290 300 310 320 pF1KSD YQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQG 100 110 120 130 140 150 330 340 350 360 370 380 pF1KSD HLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDT 160 170 180 190 200 210 390 400 410 420 430 440 pF1KSD WPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KSD VAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAK 280 290 300 310 320 330 510 520 530 540 550 560 pF1KSD SSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGS ::::::::::::::::: :...: ...: .. ..... : .: ... .: XP_016 SSWFGLREAKDPTQKPS------LDVSP-QSNPFFEELIADIALNSPSPAPSLPSASRAS 340 350 360 370 380 570 580 590 600 610 620 pF1KSD IQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQEL :... .: XP_016 PTPLASPGKALPEWDNTFNVFAASRLRPEARSEILAPAGVGLEAAGLQDPGPGAMTAKAA 390 400 410 420 430 440 >-- initn: 974 init1: 858 opt: 858 Z-score: 676.6 bits: 136.2 E(85289): 6e-31 Smith-Waterman score: 866; 53.9% identity (66.1% similar) in 345 aa overlap (335-653:759-1073) 310 320 330 340 350 pF1KSD TYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYN-----EEPQGP-VRHRSSI :: ....::.. : :..: .. .. . XP_016 EDASPPVSGPCLSAPASCPEGPAPIPCHSKSLALQSQHIWGTPEVGEGPEAPEAQGQDPV 730 740 750 760 770 780 360 370 380 390 400 pF1KSD S---GSLPSSGSLQA---VSSR-----FSEEG---PRSTDDTWPRGSRSNSSSEAVLGQE . ::: :. : :: ::.. : .: : : ... : ::: .: : : XP_016 GEGLGSL-SATSQQADVWVSKEDALNPFLFQGSRDPPSLSSASPPGSRESSIHS---GPE 790 800 810 820 830 840 410 420 430 440 450 pF1KSD ELSAQAKV------LAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEER :: . . : : ::: ..:. : .:.. : :...:: .: XP_016 ELPTPPEPDFPPPPLPPWASH---HRGGPSPPCSPLSEAWPLTTSSAPPGE--------- 850 860 870 880 890 460 470 480 490 500 510 pF1KSD KPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDP : .:. :. : . : : . ::: : : :..: XP_016 -P--ALLPGPHE--PSPPGGSPALLREDLAAATPASPLVLLPLET---------RPAEEP 900 910 920 930 520 530 540 550 560 570 pF1KSD TQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSASPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 940 950 960 970 980 990 580 590 600 610 620 630 pF1KSD MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIM 1000 1010 1020 1030 1040 1050 640 650 pF1KSD ETSPTLLQIPPGPPK ::::::::::::::: XP_016 ETSPTLLQIPPGPPK 1060 1070 653 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:47:55 2016 done: Thu Nov 3 03:47:57 2016 Total Scan time: 10.450 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]