Result of FASTA (omim) for pF1KSDA0871
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0871, 469 aa
  1>>>pF1KSDA0871 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.3878+/-0.000596; mu= -0.4359+/- 0.037
 mean_var=338.0438+/-70.453, 0's: 0 Z-trim(115.1): 53  B-trim: 336 in 1/57
 Lambda= 0.069757
 statistics sampled from 25226 (25274) to 25226 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.296), width:  16
 Scan time:  8.270

The best scores are:                                      opt bits E(85289)
NP_055776 (OMIM: 611194) protein RUFY3 isoform 2 [ ( 469) 2996 316.1 1.3e-85
NP_001032519 (OMIM: 611194) protein RUFY3 isoform  ( 620) 2846 301.1 5.6e-81
NP_001332769 (OMIM: 611194) protein RUFY3 isoform  ( 416) 2593 275.5   2e-73
NP_001278923 (OMIM: 611194) protein RUFY3 isoform  ( 487) 2593 275.5 2.2e-73
XP_011530057 (OMIM: 611194) PREDICTED: protein RUF ( 529) 2579 274.2 6.2e-73
XP_016863381 (OMIM: 611194) PREDICTED: protein RUF ( 405) 2549 271.0 4.2e-72
NP_001278922 (OMIM: 611194) protein RUFY3 isoform  ( 567) 2443 260.5 8.5e-69
XP_005265713 (OMIM: 611194) PREDICTED: protein RUF ( 638) 2443 260.6 9.2e-69
XP_011530058 (OMIM: 611194) PREDICTED: protein RUF ( 518) 2434 259.6 1.5e-68
NP_001124181 (OMIM: 611194) protein RUFY3 isoform  ( 506) 2429 259.1 2.1e-68
XP_011530056 (OMIM: 611194) PREDICTED: protein RUF ( 586) 2429 259.1 2.3e-68
XP_016863379 (OMIM: 611194) PREDICTED: protein RUF ( 587) 2429 259.1 2.3e-68
XP_011530054 (OMIM: 611194) PREDICTED: protein RUF ( 621) 2429 259.2 2.4e-68
XP_011530055 (OMIM: 611194) PREDICTED: protein RUF ( 621) 2429 259.2 2.4e-68
XP_011530053 (OMIM: 611194) PREDICTED: protein RUF ( 657) 2429 259.2 2.5e-68
XP_011530052 (OMIM: 611194) PREDICTED: protein RUF ( 680) 2429 259.2 2.6e-68
XP_005265715 (OMIM: 611194) PREDICTED: protein RUF ( 556) 2399 256.1 1.8e-67
XP_005270013 (OMIM: 610328) PREDICTED: RUN and FYV ( 585) 1321 147.6 8.5e-35
XP_016865380 (OMIM: 610327) PREDICTED: RUN and FYV ( 578) 1298 145.3 4.2e-34
XP_006714984 (OMIM: 610327) PREDICTED: RUN and FYV ( 686) 1298 145.4 4.7e-34
NP_001317032 (OMIM: 610328) RUN and FYVE domain-co ( 606) 1286 144.1   1e-33
XP_011538244 (OMIM: 610328) PREDICTED: RUN and FYV ( 606) 1286 144.1   1e-33
NP_060457 (OMIM: 610328) RUN and FYVE domain-conta ( 641) 1286 144.1   1e-33
NP_001035541 (OMIM: 610327) RUN and FYVE domain-co ( 600) 1276 143.1   2e-33
NP_001035542 (OMIM: 610327) RUN and FYVE domain-co ( 600) 1276 143.1   2e-33
NP_079434 (OMIM: 610327) RUN and FYVE domain-conta ( 708) 1276 143.2 2.2e-33
XP_005270012 (OMIM: 610328) PREDICTED: RUN and FYV ( 590) 1247 140.2 1.5e-32
NP_001265154 (OMIM: 610328) RUN and FYVE domain-co ( 379)  994 114.5 5.2e-25
NP_001035882 (OMIM: 610328) RUN and FYVE domain-co ( 403)  656 80.5 9.4e-15
XP_005270014 (OMIM: 610328) PREDICTED: RUN and FYV ( 572)  645 79.6 2.5e-14
XP_005270010 (OMIM: 610328) PREDICTED: RUN and FYV ( 607)  645 79.6 2.6e-14
XP_005266050 (OMIM: 610327) PREDICTED: RUN and FYV ( 465)  604 75.3 3.9e-13
XP_016865382 (OMIM: 610327) PREDICTED: RUN and FYV ( 416)  438 58.6 3.8e-08
XP_016865381 (OMIM: 610327) PREDICTED: RUN and FYV ( 438)  378 52.6 2.6e-06
NP_001138298 (OMIM: 605448) RUN domain-containing  ( 400)  376 52.3 2.8e-06
XP_005257021 (OMIM: 605448) PREDICTED: RUN domain- ( 441)  376 52.4   3e-06
XP_016879526 (OMIM: 605448) PREDICTED: RUN domain- ( 469)  376 52.4 3.1e-06
XP_016879529 (OMIM: 605448) PREDICTED: RUN domain- ( 401)  370 51.7 4.3e-06
XP_016879525 (OMIM: 605448) PREDICTED: RUN domain- ( 470)  370 51.8 4.8e-06
XP_016865383 (OMIM: 610327) PREDICTED: RUN and FYV ( 368)  364 51.1 6.2e-06
XP_006714985 (OMIM: 610327) PREDICTED: RUN and FYV ( 368)  364 51.1 6.2e-06
NP_006686 (OMIM: 605448) RUN domain-containing pro ( 405)  361 50.8 8.1e-06
XP_016879528 (OMIM: 605448) PREDICTED: RUN domain- ( 433)  361 50.9 8.5e-06
XP_016879527 (OMIM: 605448) PREDICTED: RUN domain- ( 434)  361 50.9 8.5e-06
NP_001138297 (OMIM: 605448) RUN domain-containing  ( 446)  361 50.9 8.7e-06
XP_016879524 (OMIM: 605448) PREDICTED: RUN domain- ( 474)  361 50.9   9e-06
XP_016865384 (OMIM: 610327) PREDICTED: RUN and FYV ( 310)  339 48.5 3.2e-05


>>NP_055776 (OMIM: 611194) protein RUFY3 isoform 2 [Homo  (469 aa)
 initn: 2996 init1: 2996 opt: 2996  Z-score: 1657.8  bits: 316.1 E(85289): 1.3e-85
Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)

               10        20        30        40        50        60
pF1KSD MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD KALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD YLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVK
              370       380       390       400       410       420

              430       440       450       460         
pF1KSD QKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAANKLIPKHH
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAANKLIPKHH
              430       440       450       460         

>>NP_001032519 (OMIM: 611194) protein RUFY3 isoform 1 [H  (620 aa)
 initn: 2846 init1: 2846 opt: 2846  Z-score: 1574.8  bits: 301.1 E(85289): 5.6e-81
Smith-Waterman score: 2846; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)

               10        20        30        40        50        60
pF1KSD MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD KALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD YLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVK
              370       380       390       400       410       420

              430       440       450       460                    
pF1KSD QKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAANKLIPKHH           
       :::::::::::::::::::::::::                                   
NP_001 QKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKINSLQLEVE
              430       440       450       460       470       480

>>NP_001332769 (OMIM: 611194) protein RUFY3 isoform 6 [H  (416 aa)
 initn: 2593 init1: 2593 opt: 2593  Z-score: 1439.2  bits: 275.5 E(85289): 2e-73
Smith-Waterman score: 2593; 100.0% identity (100.0% similar) in 411 aa overlap (59-469:6-416)

       30        40        50        60        70        80        
pF1KSD CKFRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESAL
                                     ::::::::::::::::::::::::::::::
NP_001                          MRDDTEDPNYLMANERMNLMNMAKLSIKGLIESAL
                                        10        20        30     

       90       100       110       120       130       140        
pF1KSD NLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITA
          40        50        60        70        80        90     

      150       160       170       180       190       200        
pF1KSD SVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAII
         100       110       120       130       140       150     

      210       220       230       240       250       260        
pF1KSD AGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVE
         160       170       180       190       200       210     

      270       280       290       300       310       320        
pF1KSD ELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNR
         220       230       240       250       260       270     

      330       340       350       360       370       380        
pF1KSD KGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQ
         280       290       300       310       320       330     

      390       400       410       420       430       440        
pF1KSD DALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEK
         340       350       360       370       380       390     

      450       460         
pF1KSD DLVKQAKTLNSAANKLIPKHH
       :::::::::::::::::::::
NP_001 DLVKQAKTLNSAANKLIPKHH
         400       410      

>>NP_001278923 (OMIM: 611194) protein RUFY3 isoform 5 [H  (487 aa)
 initn: 2593 init1: 2593 opt: 2593  Z-score: 1438.4  bits: 275.5 E(85289): 2.2e-73
Smith-Waterman score: 2950; 96.3% identity (96.3% similar) in 487 aa overlap (1-469:1-487)

               10        20        30        40        50        60
pF1KSD MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
               10        20        30        40        50        60

                                 70        80        90       100  
pF1KSD ------------------PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQ
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 SWEDLTDLVEQMRDDTEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQ
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KSD QFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGR
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KSD GRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
              190       200       210       220       230       240

            230       240       250       260       270       280  
pF1KSD CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQ
              250       260       270       280       290       300

            290       300       310       320       330       340  
pF1KSD AKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQAL
              310       320       330       340       350       360

            350       360       370       380       390       400  
pF1KSD SEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
              370       380       390       400       410       420

            410       420       430       440       450       460  
pF1KSD ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAAN
              430       440       450       460       470       480

              
pF1KSD KLIPKHH
       :::::::
NP_001 KLIPKHH
              

>>XP_011530057 (OMIM: 611194) PREDICTED: protein RUFY3 i  (529 aa)
 initn: 2579 init1: 2579 opt: 2579  Z-score: 1430.4  bits: 274.2 E(85289): 6.2e-73
Smith-Waterman score: 2579; 100.0% identity (100.0% similar) in 409 aa overlap (61-469:121-529)

               40        50        60        70        80        90
pF1KSD FRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNL
                                     ::::::::::::::::::::::::::::::
XP_011 TPPSPGSPLPFLLLSYPSGGGGSSGSGKHHPNYLMANERMNLMNMAKLSIKGLIESALNL
              100       110       120       130       140       150

              100       110       120       130       140       150
pF1KSD GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
              160       170       180       190       200       210

              160       170       180       190       200       210
pF1KSD KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
              220       230       240       250       260       270

              220       230       240       250       260       270
pF1KSD LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
              280       290       300       310       320       330

              280       290       300       310       320       330
pF1KSD NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
              340       350       360       370       380       390

              340       350       360       370       380       390
pF1KSD PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
              400       410       420       430       440       450

              400       410       420       430       440       450
pF1KSD LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDL
              460       470       480       490       500       510

              460         
pF1KSD VKQAKTLNSAANKLIPKHH
       :::::::::::::::::::
XP_011 VKQAKTLNSAANKLIPKHH
              520         

>>XP_016863381 (OMIM: 611194) PREDICTED: protein RUFY3 i  (405 aa)
 initn: 2549 init1: 2549 opt: 2549  Z-score: 1415.4  bits: 271.0 E(85289): 4.2e-72
Smith-Waterman score: 2549; 100.0% identity (100.0% similar) in 405 aa overlap (65-469:1-405)

           40        50        60        70        80        90    
pF1KSD MDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTL
                                     ::::::::::::::::::::::::::::::
XP_016                               MANERMNLMNMAKLSIKGLIESALNLGRTL
                                             10        20        30

          100       110       120       130       140       150    
pF1KSD DSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLP
               40        50        60        70        80        90

          160       170       180       190       200       210    
pF1KSD GLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVG
              100       110       120       130       140       150

          220       230       240       250       260       270    
pF1KSD LNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHL
              160       170       180       190       200       210

          280       290       300       310       320       330    
pF1KSD NATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQD
              220       230       240       250       260       270

          340       350       360       370       380       390    
pF1KSD RTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSL
              280       290       300       310       320       330

          400       410       420       430       440       450    
pF1KSD RQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQA
              340       350       360       370       380       390

          460         
pF1KSD KTLNSAANKLIPKHH
       :::::::::::::::
XP_016 KTLNSAANKLIPKHH
              400     

>>NP_001278922 (OMIM: 611194) protein RUFY3 isoform 4 [H  (567 aa)
 initn: 2443 init1: 2443 opt: 2443  Z-score: 1356.1  bits: 260.5 E(85289): 8.5e-69
Smith-Waterman score: 2443; 100.0% identity (100.0% similar) in 387 aa overlap (59-445:6-392)

       30        40        50        60        70        80        
pF1KSD CKFRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESAL
                                     ::::::::::::::::::::::::::::::
NP_001                          MRDDTEDPNYLMANERMNLMNMAKLSIKGLIESAL
                                        10        20        30     

       90       100       110       120       130       140        
pF1KSD NLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITA
          40        50        60        70        80        90     

      150       160       170       180       190       200        
pF1KSD SVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAII
         100       110       120       130       140       150     

      210       220       230       240       250       260        
pF1KSD AGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVE
         160       170       180       190       200       210     

      270       280       290       300       310       320        
pF1KSD ELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNR
         220       230       240       250       260       270     

      330       340       350       360       370       380        
pF1KSD KGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQ
         280       290       300       310       320       330     

      390       400       410       420       430       440        
pF1KSD DALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 DALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLR
         340       350       360       370       380       390     

      450       460                                                
pF1KSD DLVKQAKTLNSAANKLIPKHH                                       
                                                                   
NP_001 QAERSRQSAELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELELKQEKERRLQNDRSIP
         400       410       420       430       440       450     

>>XP_005265713 (OMIM: 611194) PREDICTED: protein RUFY3 i  (638 aa)
 initn: 2443 init1: 2443 opt: 2443  Z-score: 1355.5  bits: 260.6 E(85289): 9.2e-69
Smith-Waterman score: 2800; 96.1% identity (96.1% similar) in 463 aa overlap (1-445:1-463)

               10        20        30        40        50        60
pF1KSD MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHED
               10        20        30        40        50        60

                                 70        80        90       100  
pF1KSD ------------------PNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQ
                         ::::::::::::::::::::::::::::::::::::::::::
XP_005 SWEDLTDLVEQMRDDTEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQ
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KSD QFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGR
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KSD GRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANF
              190       200       210       220       230       240

            230       240       250       260       270       280  
pF1KSD CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQ
              250       260       270       280       290       300

            290       300       310       320       330       340  
pF1KSD AKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKGPKQDRTAEGQAL
              310       320       330       340       350       360

            350       360       370       380       390       400  
pF1KSD SEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLR
              370       380       390       400       410       420

            410       420       430       440       450       460  
pF1KSD ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAAN
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_005 ALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNR
              430       440       450       460       470       480

                                                                   
pF1KSD KLIPKHH                                                     
                                                                   
XP_005 LFKQDFGDKINSLQLEVEELTRQRNQLELELKQEKERRLQNDRSIPGRGSQKSESKMDGK
              490       500       510       520       530       540

>>XP_011530058 (OMIM: 611194) PREDICTED: protein RUFY3 i  (518 aa)
 initn: 2434 init1: 2434 opt: 2434  Z-score: 1351.6  bits: 259.6 E(85289): 1.5e-68
Smith-Waterman score: 2434; 97.5% identity (98.0% similar) in 398 aa overlap (61-458:121-518)

               40        50        60        70        80        90
pF1KSD FRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNL
                                     ::::::::::::::::::::::::::::::
XP_011 TPPSPGSPLPFLLLSYPSGGGGSSGSGKHHPNYLMANERMNLMNMAKLSIKGLIESALNL
              100       110       120       130       140       150

              100       110       120       130       140       150
pF1KSD GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
              160       170       180       190       200       210

              160       170       180       190       200       210
pF1KSD KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
              220       230       240       250       260       270

              220       230       240       250       260       270
pF1KSD LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
              280       290       300       310       320       330

              280       290       300       310       320       330
pF1KSD NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
              340       350       360       370       380       390

              340       350       360       370       380       390
pF1KSD PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
              400       410       420       430       440       450

              400       410       420       430       440       450
pF1KSD LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::   . 
XP_011 LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRMGST
              460       470       480       490       500       510

              460         
pF1KSD VKQAKTLNSAANKLIPKHH
         . : ::           
XP_011 KCKRKMLN           
                          

>>NP_001124181 (OMIM: 611194) protein RUFY3 isoform 3 [H  (506 aa)
 initn: 2429 init1: 2429 opt: 2429  Z-score: 1349.0  bits: 259.1 E(85289): 2.1e-68
Smith-Waterman score: 2429; 100.0% identity (100.0% similar) in 385 aa overlap (61-445:121-505)

               40        50        60        70        80        90
pF1KSD FRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNL
                                     ::::::::::::::::::::::::::::::
NP_001 TPPSPGSPLPFLLLSYPSGGGGSSGSGKHHPNYLMANERMNLMNMAKLSIKGLIESALNL
              100       110       120       130       140       150

              100       110       120       130       140       150
pF1KSD GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASV
              160       170       180       190       200       210

              160       170       180       190       200       210
pF1KSD KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG
              220       230       240       250       260       270

              220       230       240       250       260       270
pF1KSD LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGTEGDGQITAILDQKNYVEEL
              280       290       300       310       320       330

              280       290       300       310       320       330
pF1KSD NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYILESNRKG
              340       350       360       370       380       390

              340       350       360       370       380       390
pF1KSD PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDVCEKQDA
              400       410       420       430       440       450

              400       410       420       430       440       450
pF1KSD LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 LVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQR    
              460       470       480       490       500          

              460         
pF1KSD VKQAKTLNSAANKLIPKHH




469 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 03:51:38 2016 done: Thu Nov  3 03:51:39 2016
 Total Scan time:  8.270 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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