FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0873, 447 aa 1>>>pF1KSDA0873 447 - 447 aa - 447 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4350+/-0.000476; mu= 13.1762+/- 0.029 mean_var=105.0870+/-21.613, 0's: 0 Z-trim(111.1): 21 B-trim: 182 in 1/50 Lambda= 0.125112 statistics sampled from 19658 (19667) to 19658 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.231), width: 16 Scan time: 7.920 The best scores are: opt bits E(85289) NP_001015048 (OMIM: 603885) BAG family molecular c ( 447) 2879 530.7 2.9e-150 NP_004864 (OMIM: 603885) BAG family molecular chap ( 447) 2879 530.7 2.9e-150 NP_001015049 (OMIM: 603885) BAG family molecular c ( 488) 2879 530.8 3.1e-150 XP_005270344 (OMIM: 603883,612954,613881) PREDICTE ( 574) 230 52.7 3e-06 NP_004272 (OMIM: 603883,612954,613881) BAG family ( 575) 230 52.7 3e-06 NP_001191807 (OMIM: 603884) BAG family molecular c ( 421) 200 47.2 0.0001 NP_004865 (OMIM: 603884) BAG family molecular chap ( 457) 200 47.2 0.00011 >>NP_001015048 (OMIM: 603885) BAG family molecular chape (447 aa) initn: 2879 init1: 2879 opt: 2879 Z-score: 2818.7 bits: 530.7 E(85289): 2.9e-150 Smith-Waterman score: 2879; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFAC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKC 370 380 390 400 410 420 430 440 pF1KSD KAARKQAVRLAQNILSYLDLKSDEWEY ::::::::::::::::::::::::::: NP_001 KAARKQAVRLAQNILSYLDLKSDEWEY 430 440 >>NP_004864 (OMIM: 603885) BAG family molecular chaperon (447 aa) initn: 2879 init1: 2879 opt: 2879 Z-score: 2818.7 bits: 530.7 E(85289): 2.9e-150 Smith-Waterman score: 2879; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFAC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKC 370 380 390 400 410 420 430 440 pF1KSD KAARKQAVRLAQNILSYLDLKSDEWEY ::::::::::::::::::::::::::: NP_004 KAARKQAVRLAQNILSYLDLKSDEWEY 430 440 >>NP_001015049 (OMIM: 603885) BAG family molecular chape (488 aa) initn: 2879 init1: 2879 opt: 2879 Z-score: 2818.2 bits: 530.8 E(85289): 3.1e-150 Smith-Waterman score: 2879; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:42-488) 10 20 30 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGF :::::::::::::::::::::::::::::: NP_001 PFDRNQELETCIRPLWTPSGSACETEHNKSMDMGNQHPSISRLQEIQKEVKSVEQQVIGF 20 30 40 50 60 70 40 50 60 70 80 90 pF1KSD SGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPH 80 90 100 110 120 130 100 110 120 130 140 150 pF1KSD RIEIQNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIEIQNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARY 140 150 160 170 180 190 160 170 180 190 200 210 pF1KSD HTLTKICAVQEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVLIALLMGVNNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTLTKICAVQEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVLIALLMGVNNN 200 210 220 230 240 250 220 230 240 250 260 270 pF1KSD ETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADTTKAFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADTTKAFDL 260 270 280 290 300 310 280 290 300 310 320 330 pF1KSD RQNHSILKIEKVLKRMREIKNELLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQNHSILKIEKVLKRMREIKNELLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIRE 320 330 340 350 360 370 340 350 360 370 380 390 pF1KSD ARRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNR 380 390 400 410 420 430 400 410 420 430 440 pF1KSD TDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY 440 450 460 470 480 >>XP_005270344 (OMIM: 603883,612954,613881) PREDICTED: B (574 aa) initn: 418 init1: 222 opt: 230 Z-score: 233.1 bits: 52.7 E(85289): 3e-06 Smith-Waterman score: 230; 35.5% identity (79.6% similar) in 93 aa overlap (6-97:417-509) 10 20 30 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSD .::.. ... : ..:...:: : .: : . XP_005 KSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKT 390 400 410 420 430 440 40 50 60 70 80 90 pF1KSD DKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNA-NHPHRIEI ::.: .:. :::.:. .:::: ::..:..:::. ...... .:..:::.: . : .... XP_005 DKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQV 450 460 470 480 490 500 100 110 120 130 140 150 pF1KSD QNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLT .. XP_005 YELQPSNLEADQPLQAIMEMGAVAADKGKKNAGNAEDPHTETQQPEATAAATSNPSSMTD 510 520 530 540 550 560 >>NP_004272 (OMIM: 603883,612954,613881) BAG family mole (575 aa) initn: 282 init1: 222 opt: 230 Z-score: 233.1 bits: 52.7 E(85289): 3e-06 Smith-Waterman score: 230; 35.5% identity (79.6% similar) in 93 aa overlap (6-97:418-510) 10 20 30 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSD .::.. ... : ..:...:: : .: : . NP_004 KSVATEERAAPSTAPAEATPPKPGEAEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKT 390 400 410 420 430 440 40 50 60 70 80 90 pF1KSD DKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNA-NHPHRIEI ::.: .:. :::.:. .:::: ::..:..:::. ...... .:..:::.: . : .... NP_004 DKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQV 450 460 470 480 490 500 100 110 120 130 140 150 pF1KSD QNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLT .. NP_004 YELQPSNLEADQPLQAIMEMGAVAADKGKKNAGNAEDPHTETQQPEATAAATSNPSSMTD 510 520 530 540 550 560 >>NP_001191807 (OMIM: 603884) BAG family molecular chape (421 aa) initn: 377 init1: 200 opt: 200 Z-score: 205.8 bits: 47.2 E(85289): 0.0001 Smith-Waterman score: 200; 41.6% identity (79.2% similar) in 77 aa overlap (8-84:342-418) 10 20 30 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDK :::... .. ..:. .::.: : : . :: NP_001 YGNATSDHPNNQDQSSSLPEECVPSDESTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDK 320 330 340 350 360 370 40 50 60 70 80 90 pF1KSD NYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNI : ::..:::.:.:.:::.: :. ...::::.:. . . .:..::. NP_001 AYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL 380 390 400 410 420 100 110 120 130 140 150 pF1KSD FEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKIC >>NP_004865 (OMIM: 603884) BAG family molecular chaperon (457 aa) initn: 377 init1: 200 opt: 200 Z-score: 205.2 bits: 47.2 E(85289): 0.00011 Smith-Waterman score: 200; 41.6% identity (79.2% similar) in 77 aa overlap (8-84:378-454) 10 20 30 pF1KSD MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDK :::... .. ..:. .::.: : : . :: NP_004 YGNATSDHPNNQDQSSSLPEECVPSDESTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDK 350 360 370 380 390 400 40 50 60 70 80 90 pF1KSD NYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNI : ::..:::.:.:.:::.: :. ...::::.:. . . .:..::. NP_004 AYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL 410 420 430 440 450 100 110 120 130 140 150 pF1KSD FEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKIC 447 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 03:52:09 2016 done: Thu Nov 3 03:52:10 2016 Total Scan time: 7.920 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]